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Tau tubulin kinase 2 Antibody

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Western Blot: Tau tubulin kinase 2 Antibody [NBP1-92476] - Analysis in control (vector only transfected HEK293T lysate) and TTBK2 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian ...read more
Immunohistochemistry-Paraffin: Tau tubulin kinase 2 Antibody [NBP1-92476] - Staining of human testis shows weak to moderate cytoplasmic positivity in cells in seminiferous ducts.
Immunohistochemistry-Paraffin: Tau tubulin kinase 2 Antibody [NBP1-92476] - Staining of human Fallopian tube shows strong positivity in cilia in glandular cells.
Immunohistochemistry-Paraffin: Tau tubulin kinase 2 Antibody [NBP1-92476] - Staining of human prostate shows moderate cytoplasmic positivity in smooth muscle cells.
Immunohistochemistry-Paraffin: Tau tubulin kinase 2 Antibody [NBP1-92476] - Staining of human skeletal muscle shows very weak positivity in myocytes.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ICC/IF, IHC, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

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Tau tubulin kinase 2 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: TTEPLDVTKTQTFSVVPNQDKNNEIMKLLTVGTSEISSRDIDPHVEGQIGQVAEMQKNKISKDDDIMSEDLPGHQGDLSTFLHQEGKREKITPRNGELFHCVS
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TTBK2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:500 - 1:1000
  • Immunohistochemistry-Paraffin 1:500 - 1:1000
  • Immunoprecipitation
  • Western Blot 0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF, IP reactivity reported in (PMID : 24982133).
Control Peptide
Tau tubulin kinase 2 Recombinant Protein Antigen (NBP1-92476PEP)
Publications
Read Publications using
NBP1-92476 in the following applications:

Reactivity Notes

Human reactivity reported in scientific literature (PMID: 24982133). Mouse reactivity reported in scientific literature (PMID: 25599390).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Tau tubulin kinase 2 Antibody

  • EC 2.7.11
  • EC 2.7.11.1
  • KIAA0847tau-tubulin kinase 2
  • SCA11
  • spinocerebellar ataxia 11
  • tau tubulin kinase 2
  • TTBK

Background

The Tau tubulin kinase 2 gene encodes a serine-threonine kinase that putatively phosphorylates tau and tubulin proteins. Mutations in thisgene cause spinocerebellar ataxia type 11 (SCA11); a neurodegenerative disease characterized by progressive ataxia andatrophy of the cere

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Tau tubulin kinase 2 Antibody (NBP1-92476)(2)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 2 applications: ICC/IF, IP.


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ICC/IF
(2)
IP
(1)
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(1)
Mouse
(1)
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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol TTBK2