Western Blot: Tau tubulin kinase 2 Antibody [NBP1-92476] - Analysis in control (vector only transfected HEK293T lysate) and TTBK2 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian ...read more
Immunohistochemistry-Paraffin: Tau tubulin kinase 2 Antibody [NBP1-92476] - Staining of human testis shows weak to moderate cytoplasmic positivity in cells in seminiferous ducts.
Immunohistochemistry-Paraffin: Tau tubulin kinase 2 Antibody [NBP1-92476] - Staining of human Fallopian tube shows strong positivity in cilia in glandular cells.
Immunohistochemistry-Paraffin: Tau tubulin kinase 2 Antibody [NBP1-92476] - Staining of human prostate shows moderate cytoplasmic positivity in smooth muscle cells.
Immunohistochemistry-Paraffin: Tau tubulin kinase 2 Antibody [NBP1-92476] - Staining of human skeletal muscle shows very weak positivity in myocytes.
This antibody was developed against Recombinant Protein corresponding to amino acids: TTEPLDVTKTQTFSVVPNQDKNNEIMKLLTVGTSEISSRDIDPHVEGQIGQVAEMQKNKISKDDDIMSEDLPGHQGDLSTFLHQEGKREKITPRNGELFHCVS
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TTBK2
Purity
Immunogen affinity purified
Innovator's Reward
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Human reactivity reported in scientific literature (PMID: 24982133). Mouse reactivity reported in scientific literature (PMID: 25599390).
Packaging, Storage & Formulations
Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified
Alternate Names for Tau tubulin kinase 2 Antibody
EC 2.7.11
EC 2.7.11.1
KIAA0847tau-tubulin kinase 2
SCA11
spinocerebellar ataxia 11
tau tubulin kinase 2
TTBK
Background
The Tau tubulin kinase 2 gene encodes a serine-threonine kinase that putatively phosphorylates tau and tubulin proteins. Mutations in thisgene cause spinocerebellar ataxia type 11 (SCA11); a neurodegenerative disease characterized by progressive ataxia andatrophy of the cere
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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