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TAO Kinase 1 Antibody (TAO1 1.2) - BSA Free

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Western Blot: TAO Kinase 1 Antibody (TAO1 1.2) [NBP2-50324] - HeLa cells were transfected with Negative control siRNA (Neg) or TAO1 siRNAs to assess the extent of protein depletion
Genetic Strategies: Western Blot: TAO Kinase 1 Antibody (TAO1 1.2) [NBP2-50324] - HeLa cells were transfected with Negative control siRNA (Neg) or TAO1 siRNAs to assess the extent of protein depletion

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF, KD
Clone
TAO1 1.2
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml
Validated by:
     

Genetic Strategies

    

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-50324AF350
Alexa Fluor 405
NBP2-50324AF405
Alexa Fluor 488
NBP2-50324AF488
Alexa Fluor 532
NBP2-50324AF532
Alexa Fluor 594
NBP2-50324AF594
Alexa Fluor 647
NBP2-50324AF647
Alexa Fluor 700
NBP2-50324AF700
Alexa Fluor 750
NBP2-50324AF750
Biotin
NBP2-50324B
CoraFluor 1
NBP2-50324CL1
DyLight 350
NBP2-50324UV
DyLight 405
NBP2-50324V
DyLight 488
NBP2-50324G
DyLight 550
NBP2-50324R
DyLight 594
NBP2-50324DL594
DyLight 650
NBP2-50324C
DyLight 680
NBP2-50324FR
DyLight 755
NBP2-50324IR
HRP
NBP2-50324H
Janelia Fluor 525
NBP2-50324JF525
Janelia Fluor 549
NBP2-50324JF549
Janelia Fluor 585
NBP2-50324JF585
Janelia Fluor 635
NBP2-50324JF635
Janelia Fluor 646
NBP2-50324JF646
Janelia Fluor 669
NBP2-50324JF669
mFluor Violet 450 SE
NBP2-50324MFV450
mFluor Violet 500 SE
NBP2-50324MFV500
mFluor Violet 610 SE
NBP2-50324MFV610
View Available Formulations
Catalog# & Formulation Size Price
BSA Free
NBP2-50324-0.025ml
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TAO Kinase 1 Antibody (TAO1 1.2) - BSA Free Summary

Description
Clone also known as TAO_1.2_VMD
Immunogen
His-tagged recombinant human TAO Kinase 1 (722-1001) generated in E.coli
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
TAOK1
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:10 - 1:500
  • Knockdown Validated
  • Western Blot 1:100 - 1:2000
Application Notes
Staining Pattern: Cellular Cortex. Positive control(s): Lysate from HeLa cell line.
Theoretical MW
120 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Protein A purified

Alternate Names for TAO Kinase 1 Antibody (TAO1 1.2) - BSA Free

  • EC 2.7.11
  • FLJ14314
  • hKFC-B
  • hTAOK1
  • KIAA1361
  • KIAA1361STE20-like kinase PSK2
  • Kinase from chicken homolog B
  • MAP3K16
  • MAP3K16EC 2.7.11.1
  • MARK Kinase
  • MARKK
  • MARKKmicrotubule affinity regulating kinase kinase
  • PSK2
  • PSK-2
  • PSK2serine/threonine kinase TAO1
  • serine/threonine-protein kinase TAO1
  • TAO Kinase 1
  • TAO1serine/threonine protein kinase TAO1 homolog
  • TAOK1
  • Thousand and one amino acid protein 1

Background

TAOK1, a member of the Ste20 kinase family, is a TAO type protein kinase that acts as an upstream activator to MARK by phosphorylation. When activated, MARK enhances microtubule dynamics and leads to phosphorylation and detachment of tau or equivalent MAPs from microtubules. Overexpression of MARK eventually leads to microtubule breakdown and cell death, but in neuronal cells the primary effect is to allow the development of neurites during differentiation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol TAOK1