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TAO Kinase 1 Antibody (TAO1 1.2) [DyLight 594]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF, KD
Clone
TAO1 1.2
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 594

Order Details

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TAO Kinase 1 Antibody (TAO1 1.2) [DyLight 594] Summary

Description
Clone also known as TAO_1.2_VMD
Immunogen
His-tagged recombinant human TAO Kinase 1 (722-1001) generated in E.coli
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
TAOK1
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Knockdown Validated
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for TAO Kinase 1 Antibody (TAO1 1.2) [DyLight 594]

  • EC 2.7.11
  • FLJ14314
  • hKFC-B
  • hTAOK1
  • KIAA1361
  • KIAA1361STE20-like kinase PSK2
  • Kinase from chicken homolog B
  • MAP3K16
  • MAP3K16EC 2.7.11.1
  • MARK Kinase
  • MARKK
  • MARKKmicrotubule affinity regulating kinase kinase
  • PSK2
  • PSK-2
  • PSK2serine/threonine kinase TAO1
  • serine/threonine-protein kinase TAO1
  • TAO Kinase 1
  • TAO1serine/threonine protein kinase TAO1 homolog
  • TAOK1
  • Thousand and one amino acid protein 1

Background

TAOK1, a member of the Ste20 kinase family, is a TAO type protein kinase that acts as an upstream activator to MARK by phosphorylation. When activated, MARK enhances microtubule dynamics and leads to phosphorylation and detachment of tau or equivalent MAPs from microtubules. Overexpression of MARK eventually leads to microtubule breakdown and cell death, but in neuronal cells the primary effect is to allow the development of neurites during differentiation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for TAO Kinase 1 Antibody (NBP2-50324DL594) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol TAOK1