Species: Hu, Mu, Rt
Applications: ELISA, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, IHC
Host: Mouse Monoclonal
Species: Hu, Mu, Rt, Po, Bt, Bv, Ca, Ch, Eq, Ha, Pm, Pm, Rb, Xp, Av, Ma-Op
Applications: ELISA, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Description
TAOK1, a member of the Ste20 kinase family, is a TAO type protein kinase that acts as an upstream activator to MARK by phosphorylation. When activated, MARK enhances microtubule dynamics and leads to phosphorylation and detachment of tau or equivalent MAPs from microtubules. Overexpression of MARK eventually leads to microtubule breakdown and cell death, but in neuronal cells the primary effect is to allow the development of neurites during differentiation.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human Human |
Product By Gene ID |
57551 |
Alternate Names |
- EC 2.7.11
- FLJ14314
- hKFC-B
- KIAA1361STE20-like kinase PSK2
- Kinase from chicken homolog B
- MAP3K16EC 2.7.11.1
- MARKKmicrotubule affinity regulating kinase kinase
- PSK2serine/threonine kinase TAO1
- serine/threonine-protein kinase TAO1
- TAO kinase 1
- TAO1serine/threonine protein kinase TAO1 homolog
- Thousand and one amino acid protein 1
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Research Areas for TAO Kinase 1
Find related products by research area and learn more about each of the different research areas below.
GPCRProtein Kinase