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STK39 Antibody

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Western Blot: STK39 Antibody [NBP1-30112] - Whole cell lysate (5, 15 and 50 ug) from HeLa cells. Antibody used at 0.04 ug/ml.
Western Blot: STK39 Antibody [NBP1-30112] - Whole cell lysate (5, 15 and 50 ug) from HeLa cells. Antibody used at 0.04 ug/ml.
Immunohistochemistry: STK39 Antibody [NBP1-30112] - Sample: FFPE section of human testicular seminoma. Antibody: Affinity purified rabbit anti- SPAK used at a dilution of 1:200 (1ug/ml). Detection: DAB

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, IP (-)
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.2 mg/ml

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STK39 Antibody Summary

Immunogen
maps to a region between residue 425 and 450 of human STE20/SPS1-related proline-alanine-rich protein kinase using the numbering given in entry AAC72238.1
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
STK39
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:100 - 1:500
  • Immunohistochemistry-Paraffin 1:100 - 1:500
  • Western Blot 1:2000-1:10000
Application Notes
Immunohistochemistry 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Immunogen affinity purified

Alternate Names for STK39 Antibody

  • DCHTsmall intestine SPAK-like kinase
  • DKFZp686K05124
  • EC 2.7.11
  • EC 2.7.11.1
  • PASK
  • proline-alanine-rich STE20-related kinase
  • serine threonine kinase 39
  • Serine/threonine-protein kinase 39
  • SPAKserine threonine kinase 39 (STE20/SPS1 homolog, yeast)
  • STE20/SPS1 homolog
  • STE20/SPS1-related proline-alanine-rich protein kinase
  • Ste20-like protein kinase
  • Ste-20-related kinase

Background

This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol STK39