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SR-AI/MSR Antibody [PE]

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Product Details

Summary
Reactivity Hu, Mu, Rt, Bv, Ca, Eq, PmSpecies Glossary
Applications WB, Flow, Func, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
PE

Order Details

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SR-AI/MSR Antibody [PE] Summary

Immunogen
Synthetic peptide made to an internal portion of human Macrophage Scavenger Receptor I (within residues 400-450). [Swiss-Prot: P21757]
Localization
Membrane; Single-pass type II membrane protein.
Predicted Species
Rat (92%), Canine (100%), Primate (93%), Equine (100%), Bovine (93%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MSR1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Proximity Ligation Assay
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for SR-AI/MSR Antibody [PE]

  • CD204 antigen
  • CD204
  • Macrophage acetylated LDL receptor I and II
  • macrophage scavenger receptor 1
  • macrophage scavenger receptor type III
  • MSR1
  • phSR1
  • phSR2
  • SCARA1
  • SCARA1macrophage scavenger receptor types I and II
  • Scavenger receptor class A member 1
  • scavenger receptor class A, member 1
  • SR-A
  • SRAI
  • SR-AI

Background

Macrophage scavenger receptors (MSR) are membrane glycoproteins that mediate the recognition and uptake of a variety of macromolecules, including modified lipoproteins, advanced glycation end (AGEs) products and amyloid b-protein (Abeta). While the normal role of MSR is associated with cell adhesion and host defense mechanisms, it also has been implicated in the development of atherosclerosis and Abeta deposition in Alzheimer's disease (AD).

In cell cultures, macrophage scavenger receptor has been shown to mediate adhesion of macrophages and other cell lines to tissue culture plastic. MSR1 antibodies are useful for research on atherosclerosis, Alzheimer's disease, and host defense.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for SR-AI/MSR Antibody (NBP1-00092PE) (0)

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Bioinformatics

Gene Symbol MSR1