Orthogonal Strategies: Immunohistochemistry-Paraffin: SLC5A12 Antibody [NBP2-49322] - Staining in human kidney and skin tissues.. Corresponding SLC5A12 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: SLC5A12 Antibody [NBP2-49322] - Staining of human lymph node shows no positivity in non-germinal center cells as expected.
Immunohistochemistry-Paraffin: SLC5A12 Antibody [NBP2-49322] - Staining of human small intestine shows weak to moderate membranous positivity in glandular cells.
Immunohistochemistry-Paraffin: SLC5A12 Antibody [NBP2-49322] - Staining of human kidney shows strong membranous positivity in cells in proximal tubules.
Immunohistochemistry-Paraffin: SLC5A12 Antibody [NBP2-49322] - Staining of human skin shows no positivity in keratinocytes as expected.
solute carrier family 5 (sodium/glucose cotransporter), member 12
Solute carrier family 5 member 12
Background
Normal blood lactate is maintained at about 1.5 mM, and little filtered lactate is excreted in urine. Reabsorption oflactate is mediated by the low-affinity Na(+)-coupled lactate transporter SLC5A12 in the initial part of the proximaltubule and by the high-affinity Na(+)-coupled lactate transporter SLC5A8 (MIM 608044) in the distal proximal tubule(Gopal et al., 2007 (PubMed 17692818)).(supplied by OMIM)
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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