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Slap Antibody

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Immunocytochemistry/Immunofluorescence: Slap Antibody [NBP2-56463] - Staining of human cell line NB-4 shows localization to nuclear membrane. Antibody staining is shown in green.
Immunocytochemistry/ Immunofluorescence: Slap Antibody [NBP2-56463] - Staining of human cell line NB-4 shows localization to nuclear membrane. Antibody staining is shown in green.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

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Slap Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: PCLTQSTAAPAVRASSSPVTLRQKTVDWRRVSRLQEDPEGTENPLGVDESLFSYGLRESIASYLSLTSEDNTSFDRKKKSISLMYGGSKRKSSFFSSPP
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SLA
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
Slap Recombinant Protein Antigen (NBP2-56463PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for Slap Antibody

  • hSLAP
  • SLA1
  • SLAP
  • SLAP1
  • SLAP-1
  • Src-like-adapter protein 1
  • Src-like-adapter
  • Src-like-adaptor

Background

Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. Involved in the negative regulation of positive selection and mitosis of T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Slap Antibody
NBP2-56463
Slap Antibody
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Applications: ICC/IF

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol SLA