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SH3BP2 Antibody

Images

 
Western Blot: SH3BP2 Antibody [NBP1-58872] - Titration: 1 ug/ml Positive Control: 721_B cell lysate.
Immunohistochemistry: SH3BP2 Antibody [NBP1-58872] - Staining of human liver cross section.
Immunohistochemistry-Paraffin: SH3BP2 Antibody [NBP1-58872] - Human kidney Tissue, antibody concentration 5 ug/ml.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

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SH3BP2 Antibody Summary

Description
The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.
Immunogen
Synthetic peptides corresponding to SH3BP2(SH3-domain binding protein 2) The peptide sequence was selected from the middle region of SH3BP2. Peptide sequence RQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEPQ. The peptide sequence for this immunogen was taken from within the described region.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SH3BP2
Purity
Affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Western Blot 1.0 ug/ml

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, 2% Sucrose
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Affinity purified

Alternate Names for SH3BP2 Antibody

  • Abl-SH3 binding protein 2
  • Cherubism
  • CRBM
  • CRPM
  • FLJ42079
  • FLJ54978,3BP-2,3BP2
  • RES4-23
  • SH3 domain-binding protein 2
  • SH3-domain binding protein 2
  • TNFAIP3 interacting protein 2

Background

SH3BP2 has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases, and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol SH3BP2
Uniprot