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Serpin A6/Cortisol Binding Globulin Antibody (SAIC-42B-10) - Azide and BSA Free

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Immunocytochemistry/Immunofluorescence: Serpin A6/Cortisol Binding Globulin Antibody (SAIC-42B-10) - Azide and BSA Free [NBP3-20108] - Immunofluorescence analysis of paraformaldehyde fixed HepG2 cells stained with the chimeric rabbit IgG version of SAIC-42B-10 (NBP3-20108) (1:100 dilution) for 1h followed by Alexa Fluor(R) 488 secondary antibody (1:1000 dilution), showing membrane and cytoplasmic staining. The nuclear stain is DAPI (blue). Panels show from left-right, top-bottom NBP3-20108, DAPI, merged channels and an isotype control. The isotype control was an unknown specificity antibody followed by staining with Alexa Fluor(R) 488 secondary antibody.
Immunocytochemistry/ Immunofluorescence: Serpin A6/Cortisol Binding Globulin Antibody (SAIC-42B-10) - Azide and BSA Free [NBP3-20108] - Immunofluorescence analysis of paraformaldehyde fixed HepG2 cells stained with the ...read more
Flow Cytometry: Serpin A6/Cortisol Binding Globulin Antibody (SAIC-42B-10) - Azide and BSA Free [NBP3-20108] - Paraformaldehyde fixed HepG2 cells permeabilized with 0.5% Triton were stained with anti-unknown specificity ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, ICC/IF, MS
Clone
SAIC-42B-10
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated
Format
Azide and BSA Free
Concentration
1 mg/ml

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-20108AF350
Alexa Fluor 405
NBP3-20108AF405
Alexa Fluor 488
NBP3-20108AF488
Alexa Fluor 532
NBP3-20108AF532
Alexa Fluor 594
NBP3-20108AF594
Alexa Fluor 647
NBP3-20108AF647
Alexa Fluor 700
NBP3-20108AF700
Alexa Fluor 750
NBP3-20108AF750
Biotin
NBP3-20108B
CoraFluor 1
NBP3-20108CL1
DyLight 350
NBP3-20108UV
DyLight 405
NBP3-20108V
DyLight 488
NBP3-20108G
DyLight 550
NBP3-20108R
DyLight 594
NBP3-20108DL594
DyLight 650
NBP3-20108C
DyLight 680
NBP3-20108FR
DyLight 755
NBP3-20108IR
FITC
NBP3-20108F
HRP
NBP3-20108H
Janelia Fluor 525
NBP3-20108JF525
Janelia Fluor 549
NBP3-20108JF549
Janelia Fluor 646
NBP3-20108JF646
Janelia Fluor 669
NBP3-20108JF669
PerCP
NBP3-20108PCP
mFluor Violet 450 SE
NBP3-20108MFV450
mFluor Violet 500 SE
NBP3-20108MFV500
mFluor Violet 610 SE
NBP3-20108MFV610
View Available Formulations
Catalog# & Formulation Size Price
Azide and BSA Free
NBP3-20108-0.025mg
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Serpin A6/Cortisol Binding Globulin Antibody (SAIC-42B-10) - Azide and BSA Free Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
Peptide "AQLLQGLGFNLTER" derived from the Corticosteroid-binding globulin SERPINA6, conjugated to KLH.
Isotype
IgG Kappa
Clonality
Monoclonal
Host
Rabbit
Gene
SERPINA6
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Mass Spectrometry
  • Western Blot
Application Notes
This Ab can be used in immunoMRM.

Packaging, Storage & Formulations

Storage
Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.
Buffer
PBS
Preservative
0.02% Proclin 300
Concentration
1 mg/ml
Purity
Protein A purified

Alternate Names for Serpin A6/Cortisol Binding Globulin Antibody (SAIC-42B-10) - Azide and BSA Free

  • antitrypsin), member 6
  • CBG
  • CBGcorticosteroid-binding globulin
  • corticosteroid binding globulin
  • member 6
  • serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase
  • Serpin A6
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin)
  • transcortin

Background

Corticol binding globulin (CBG or transcotin) binds with high affinity to cortisol in plasma. Cortisol is the most potent glucocorticoid produced by the human adrenal. It is synthesized from cholesterol and its production is stimulated by pituitary adrenocorticotropic hormone (ACTH) which is regulated by corticotropin releasing factor (CRF). ACTH and CRF secretions are inhibited by high cortisol levels in a negative feedback loop. Cortisol acts through specific intracellular receptors and affects numerous physiologic systems including immune function, glucose counter regulation, vascular tone, and bone metabolism.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol SERPINA6