SERCA2 ATPase Antibody

Sarcoplasmic/endoplasmic reticulum Calcium-ATPase 2 (SERCA2) is a magnesium-dependent pump that catalyzes the hydrolysis of ATP and translocates calcium from the cytosol to the sarcoplasmic reticulum lumen. There are 2 SERCA2 isoforms that differ in the 3' UTR. The SERCA2A isoform is highly expressed in heart and slow twitch skeletal muscle and is important to the regulation of the contraction and relaxation cycle, while the SERCA2B isoform is expressed in smooth muscle and adult epidermis. SERCA2 is also known as ATP2A2, ATP2B, DAR, DD, and MGC45367.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 4 confirmed species: Human, Mouse, Rat, Chicken.

We have publications tested in 5 applications: Chemotaxis, ICC/IF, IP, RIP, WB.

Showing Publications 1 - 10 of 15. Show All 15 Publications. Collapse Publications.

Publications using NB100-237	Applications	Species
Cai B, Ma M, Zhang J et al. LncEDCH1 improves mitochondrial function to reduce muscle atrophy by interacting with SERCA2 Molecular Therapy - Nucleic Acids 2022-03-01 [PMID: 35024244] (RIP, WB, Chicken)	RIP, WB	Chicken
Dunay GA, Paragi P, Sara L et al. Depressed calcium cycling contributes to lower ischemia tolerance in hearts of estrogen-deficient rats. Menopause. 2014-12-15 [PMID: 25513985] (WB, Rat)	WB	Rat
Nensa FM, Neumann MH, Schrotter A et al. Amyloid Beta A4 Precursor Protein-binding Family B Member 1 (FE65) Interactomics Revealed Synaptic Vesicle Glycoprotein 2A (SV2A) and Sarcoplasmic/Endoplasmic Reticulum Calcium ATPase 2 (SERCA2) as New Binding Proteins in the Human Brain. Mol Cell Proteomics 2014-02-01 [PMID: 24284412] (IP, Chemotaxis, WB, Human)	IP, Chemotaxis, WB	Human
Barriga M, Cal R, Cabello N et al. Low Density Lipoproteins Promote Unstable Calcium Handling Accompanied by Reduced SERCA2 and Connexin-40 Expression in Cardiomyocytes PLoS One 2013-01-01 [PMID: 23516438] (WB, Mouse)	WB	Mouse
Wang Y, Bruce AT, Tu C et al. Protein aggregation of SERCA2 mutants associated with Darier disease elicits ER stress and apoptosis in keratinocytes. J Cell Sci. 2011-11-01 [PMID: 22045735] (ICC/IF, Human)	ICC/IF	Human
Anand Mohan Prasad, Giuseppe Inesi Silencing calcineurin A subunit reduces SERCA2 expression in cardiac myocytes American Journal of Physiology - Heart and Circulatory Physiology 2012-01-01 [PMID: 21057045]
Li Q, Hueckstaedt LK, Ren J et al. The protease inhibitor UCF-101 ameliorates streptozotocin-induced mouse cardiomyocyte contractile dysfunction in vitro: role of AMP-activated protein kinase. Exp Physiol 2009-09-01 [PMID: 19561140]
Song J, Zhang XQ, Wang J et al. Regulation of cardiac myocyte contractility by phospholemman: Na+/Ca2+ exchange versus Na+ -K+ -ATPase. Am J Physiol Heart Circ Physiol 2008-10-01 [PMID: 18708446]
Yang J, Pawlyk B, Wen XH et al. Mpp4 is required for proper localization of plasma membrane calcium ATPases and maintenance of calcium homeostasis at the rod photoreceptor synaptic terminals. Hum Mol Genet 2007-05-01 [PMID: 17341488]
Nensa FM. Interaktomstudie zum Alzheimer - relevanten Adapterpro tein FE65 -Durchfuhrung eines Pulldown - Assays mit rekombinant hergestelltem Protein und humanem Hirngewebe Thesis 2016-01-01 (WB, Human)	WB	Human
Rich S, Pogoriler J, Husain AN et al. Long-term effects of epoprostenol on the pulmonary vasculature in idiopathic pulmonary arterial hypertension. Chest 2010-11-01 [PMID: 21051399]
Prasad AM, Inesi G. Effects of thapsigargin and phenylephrine on calcineurin and protein kinase C signaling functions in cardiac myocytes. Am J Physiol Cell Physiol. 2009-05-01 [PMID: 19244478]
Leatherbury L, Yu Q, Chatterjee B et al. A novel mouse model of X-linked cardiac hypertrophy. Am J Physiol Heart Circ Physiol 2008-04-18 [PMID: 18424640]
Luckey, Stephen W et al. Blocking cardiac growth in hypertrophic cardiomyopathy induces cardiac dysfunction decreased survival only in males. Am J Physiol Heart Circ Physiol 292 (2):H838-H845. 2007-01-01 [PMID: 17012357]
Emter, Craig A et al. Low-Intensity Exercise Training Delays the Onset of Decompensated Heart Failure in the Spontaneously Hypertensive Heart Failure (SHHF) RatAJPHC . Physiol 289 (5):H2030-H2038. 2005-01-01 [PMID: 15994855]
Show All 15 Publications. Collapse Publications.

Array NB100-237

• SERCA2 ATPase Antibodies
• SERCA2 ATPase ELISA Kits
• SERCA2 ATPase Proteins