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SERCA2 ATPase Antibody [PerCP]

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Product Details

Summary
Reactivity Hu, Mu, Rt, Ch, Po, Ca, Fe, RbSpecies Glossary
Applications WB, ICC/IF, IP, ChIP
Clonality
Polyclonal
Host
Rabbit
Conjugate
PerCP

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB100-237AF350
Alexa Fluor 405
NB100-237AF405
Alexa Fluor 488
NB100-237AF488
Alexa Fluor 532
NB100-237AF532
Alexa Fluor 594
NB100-237AF594
Alexa Fluor 647
NB100-237AF647
Alexa Fluor 700
NB100-237AF700
Alexa Fluor 750
NB100-237AF750
Allophycocyanin
NB100-237APC
Biotin
NB100-237B
CoraFluor 1
NB100-237CL1
DyLight 350
NB100-237UV
DyLight 405
NB100-237V
DyLight 488
NB100-237G
DyLight 550
NB100-237R
DyLight 594
NB100-237DL594
DyLight 650
NB100-237C
DyLight 680
NB100-237FR
DyLight 755
NB100-237IR
FITC
NB100-237F
HRP
NB100-237H
Janelia Fluor 525
NB100-237JF525
Janelia Fluor 549
NB100-237JF549
Janelia Fluor 646
NB100-237JF646
Janelia Fluor 669
NB100-237JF669
PE
NB100-237PE
Unconjugated
NB100-237
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SERCA2 ATPase Antibody [PerCP] Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 475 and 525 of human ATPase, Ca++ transporter, cardiac muscle, slow twitch 2 using the numbering given in entry NP_733765.1 (GeneID 488).
Localization
Endoplasmic reticulum + Sarcoplasmic reticulum membrane protein
Predicted Species
Porcine (100%), Rabbit (100%), Feline (100%), Canine (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ATP2A2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Chromatin Immunoprecipitation (ChIP)
  • Immunocytochemistry/ Immunofluorescence
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Use in Chicken reported in scientific literature (PMID:35024244) Cat (100%). Mouse reactivity reported in scientific literature (PMID:23516438). Rat reactivity reported in scientific literature (PMID: 25513985)..

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for SERCA2 ATPase Antibody [PerCP]

  • ATP2A2
  • ATP2B
  • ATP2BFLJ20293
  • ATPase, Ca++ dependent, slow-twitch, cardiac muscle-2
  • ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
  • Calcium pump 2
  • Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletalmuscle isoform
  • cardiac Ca2+ ATPase
  • DAR
  • DD
  • EC 3.6.3
  • EC 3.6.3.8
  • Endoplasmic reticulum class 1/2 Ca(2+) ATPase
  • FLJ38063
  • MGC45367
  • sarcoplasmic/endoplasmic reticulum calcium ATPase 2
  • SERCA2 ATPase
  • SERCA2
  • SERCA2DKFZp686P0211
  • SR Ca(2+)-ATPase 2

Background

Sarcoplasmic/endoplasmic reticulum Calcium-ATPase 2 (SERCA2) is a magnesium-dependent pump that catalyzes the hydrolysis of ATP and translocates calcium from the cytosol to the sarcoplasmic reticulum lumen. There are 2 SERCA2 isoforms that differ in the 3' UTR. The SERCA2A isoform is highly expressed in heart and slow twitch skeletal muscle and is important to the regulation of the contraction and relaxation cycle, while the SERCA2B isoform is expressed in smooth muscle and adult epidermis. SERCA2 is also known as ATP2A2, ATP2B, DAR, DD, and MGC45367.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Mending a Broken Heart: New SERCA2 Gene Therapy Fights Heart Disease
While many of the proteins on our antibody database are studied in relation to their expression in diseases; others become therapies in their own right. This is the case with SERCA2 (Sarcoplasmic reticulum Calcium-ATPase 2 pump), which recently hit th...  Read full blog post.
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Bioinformatics

Gene Symbol ATP2A2