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PRPS1 Antibody

Images

 
Immunocytochemistry/ Immunofluorescence: PRPS1 Antibody [NBP2-13813] - Staining of human cell line U-251 MG shows localization to cytosol. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: PRPS1 Antibody [NBP2-13813] - Staining of human prostate shows weak nuclear positivity in smooth muscle cells.
Immunohistochemistry-Paraffin: PRPS1 Antibody [NBP2-13813] - Staining of human endometrium shows moderate nuclear positivity in stromal cells.
Immunohistochemistry-Paraffin: PRPS1 Antibody [NBP2-13813] - Staining of human lymph node shows strong nuclear positivity in non-germinal center cells.
Immunohistochemistry-Paraffin: PRPS1 Antibody [NBP2-13813] - Staining of human pancreas shows low positivity in exocrine glandular cells.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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PRPS1 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: LHASQIQVSVEAKYWCLKGGRKGLMMLKTAEKP
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PRPS1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
PRPS1 Protein (NBP2-13813PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for PRPS1 Antibody

  • CMTX5
  • CMTX5ARTS
  • deafness, X-linked 2, perceptive, congenital
  • DFN2
  • DFNX1
  • DFNX1KIAA0967
  • dJ1070B1.2 (phosphoribosyl pyrophosphate synthetase 1)
  • EC 2.7.6.1
  • Phosphoribosyl pyrophosphate synthase I
  • phosphoribosyl pyrophosphate synthetase 1
  • PPRibP
  • PRPS1
  • PRS I
  • PRSI
  • PRS-I
  • ribose-phosphate diphosphokinase 1
  • ribose-phosphate pyrophosphokinase 1

Background

The PRPS1 gene encodes an enzyme that catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for purine metabolism and nucleotide biosynthesis. Defects in this gene are a cause of phosphoribosylpyrophosp

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

FAQs for PRPS1 Antibody (NBP2-13813) (0)

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Bioinformatics

Gene Symbol PRPS1