PLZF Antibody (6318100) [Allophycocyanin]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Human PLZF is a 74 kDa nuclear protein that belongs to the POK family of transcriptional repressors. It is a 673 amino acid protein that contains an N-terminal BTB domain, followed by an acidic domain, a proline-rich region and a C-terminal zinc-finger domain. PLZF forms homodimers with RAR alpha and LAZ3 with its zinc-finger region. Alternate splice forms exist which are tissue-specific and show a deletion of either the BTB domain, the acidic region, or the proline-rich region. Human PLZF shares 96%, 97%, 96%, and 96% amino acid identity with rat, mouse, canine, and bovine PLZF, respectively.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 1 application: Flow Cytometry.

Showing Publications 1 - 7 of 7.

Publications using IC2944A	Applications	Species
Wan Rong Sia, Ying Ying Hey, Randy Foo, Lin-Fa Wang, Edwin Leeansyah Culture, expansion, and flow-cytometry-based functional analysis of pteropid bat MR1-restricted unconventional T cells STAR Protocols 2021-06-01 [PMID: 34041501]
Todd Bradley, Dimitra Peppa, Isabela Pedroza-Pacheco, Dapeng Li, Derek W. Cain, Ricardo Henao et al. RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody Responses Cell 2018-10-04 [PMID: 30270043]
D Paquin-Pro, BC Greenspun, EA Costa, AC Segurado, EG Kallas, DF Nixon, FE Leal MAIT cells are reduced in frequency and functionally impaired in human T lymphotropic virus type 1 infection: Potential clinical implications PLoS ONE, 2017-04-06;12(4):e0175345. 2017-04-06 [PMID: 28384290] (Flow Cytometry, Human)	Flow Cytometry	Human
Massot B, Michel M, Diem S, Ohnmacht C, Latour S, Dy M, Eberl G, Leite-de-Moraes M TLR-induced cytokines promote effective proinflammatory natural Th17 cell responses. J Immunol, 2014-05-07;192(12):5635-42. 2014-05-07 [PMID: 24808372] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
Leeansyah E, Loh L, Nixon D, Sandberg J Acquisition of innate-like microbial reactivity in mucosal tissues during human fetal MAIT-cell development. Nat Commun, 2014-01-01;5(0):3143. 2014-01-01 [PMID: 24452018] (Flow Cytometry, Human)	Flow Cytometry	Human
Leeansyah E, Ganesh A, Quigley M, Sonnerborg A, Andersson J, Hunt P, Somsouk M, Deeks S, Martin J, Moll M, Shacklett B, Sandberg J Activation, exhaustion, and persistent decline of the antimicrobial MR1-restricted MAIT-cell population in chronic HIV-1 infection. Blood, 2012-12-13;121(7):1124-35. 2012-12-13 [PMID: 23243281] (Flow Cytometry, Human)	Flow Cytometry	Human
Gerart S, Siberil S, Martin E, Lenoir C, Aguilar C, Picard C, Lantz O, Fischer A, Latour S Human iNKT and MAIT cells exhibit a PLZF-dependent proapoptotic propensity that is counterbalanced by XIAP. Blood, 2012-12-06;121(4):614-23. 2012-12-06 [PMID: 23223428] (Flow Cytometry, Human)	Flow Cytometry	Human

Array IC2944A

• PLZF Antibodies
• PLZF Lysate
• PLZF Proteins