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PKLR Antibody [HRP]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, IHC, WB (-)
Clonality
Polyclonal
Host
Rabbit
Conjugate
HRP

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PKLR Antibody [HRP] Summary

Immunogen
Produced in rabbits immunized with purified, recombinant Human PKLR (Accession#: NP_000289.1; Leu47-Ser574)
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PKLR
Purity
Antigen and protein A Affinity-purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
No Preservative
Purity
Antigen and protein A Affinity-purified

Alternate Names for PKLR Antibody [HRP]

  • EC 2.7.1.40
  • PK1
  • PK1PKRL
  • PKL
  • PKLR
  • PKR
  • Pyruvate Kinase 1
  • pyruvate kinase isozyme R/L
  • pyruvate kinase isozymes R/L
  • pyruvate kinase type L
  • pyruvate kinase, liver and blood cell
  • pyruvate kinase, liver and RBC
  • Red cell/liver pyruvate kinase
  • RPK
  • R-type/L-type pyruvate kinase

Background

The protein encoded by the Pyruvate Kinase gene is a pyruvate kinase that catalyzes the transphosphorylation of phosphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PKLR