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PKHD1 Antibody [mFluor Violet 500 SE]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications ELISA, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
mFluor Violet 500 SE

PKHD1 Antibody [mFluor Violet 500 SE] Summary

Immunogen
A synthetic peptide derived from the human PKHD1 protein (within residues 3800-3900). [UniProt# Q8TCZ9]
Localization
Membrane; single-pass type I membrane.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PKHD1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Peptide ELISA
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Immunogen sequence has 86% identity to mouse.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for PKHD1 Antibody [mFluor Violet 500 SE]

  • polycystic kidney and hepatic disease 1 (autosomal recessive)

Background

Found mainly in the cytoplasm and plasma membrane, PKHD1 plays an important role in protein binding and receptor activity. The protein encoded by PKHD1 has a single transmembrane (TM) spanning domain and various copies of an immunoglobulin-like plexin-transcription-factor domain. More specifically, these transcripts encode products which lack the TM and may be secreted. In humans, PKHD1 is highly expressed in the kidney by acting as a receptor protein in the cortical and medullary collecting ducts. Diseases associated with PKHD1 include polycystic kidney and hepatic disease, liver disease, neoplasia, fibrosis, cancer, adenocarcinoma and prostate cancer.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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mFluor Violet Conjugated Antibodies

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Bioinformatics

Gene Symbol PKHD1