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PI 3-Kinase p110 delta Antibody (PIK3CD/4639) - Azide and BSA Free

Images

 
Analysis of Protein Array containing more than 19,000 full-length human proteins using PI 3-Kinase p110 delta antibody (PIK3CD/4639) - Azide and BSA Free
Western blot analysis of THP-1 cell lysate using PI 3-Kinase p110 delta antibody (PIK3CD/4639) - Azide and BSA Free
Formalin-fixed, paraffin-embedded human lymph node stained with PI 3-Kinase p110 delta antibody (PIK3CD/4639) - Azide and BSA Free. Inset: PBS instead of primary antibody; secondary only negative control.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clone
PIK3CD/4639
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
Azide and BSA Free
Concentration
1 mg/ml

Order Details

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PI 3-Kinase p110 delta Antibody (PIK3CD/4639) - Azide and BSA Free Summary

Description
Antibody without azide - store at -20 to -80C.
Immunogen
Recombinant fragment of human PI 3-Kinase p110 delta protein (around aa 520-720) (exact sequence is proprietary)
Localization
Cytoplasm.
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
PIK3CD
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 1-2ug/ml
  • Western Blot 1-2ug/ml
Application Notes
Immunohistochemistry-Paraffin: 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined.

Packaging, Storage & Formulations

Storage
Store at -20 to -80C. Avoid freeze-thaw cycles.
Buffer
10mM PBS
Preservative
No Preservative
Concentration
1 mg/ml
Purity
Protein A or G purified

Alternate Names for PI 3-Kinase p110 delta Antibody (PIK3CD/4639) - Azide and BSA Free

  • EC 2.7.1
  • EC 2.7.1.153
  • p110D
  • P110DELTA
  • Phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta
  • phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • phosphoinositide-3-kinase C
  • phosphoinositide-3-kinase, catalytic, delta polypeptide
  • PI 3Kinase p110 delta
  • PI 3-Kinase p110 delta
  • PI3K
  • PI3K-delta
  • PI3-kinase p110 subunit delta
  • PI3-kinase subunit delta
  • PIK3CD
  • PtdIns-3-kinase subunit delta
  • PtdIns-3-kinase subunit p110-delta

Background

PI3-Kinases (PI3-Ks) are a family of lipid kinases that are implicated in signal transduction. PI3-K consists of two subunits; p85 and p110. The p85 subunit localize PI3-K activity to the plasma membrane while the p110 subunit contains the catalytic domain of PI3-K. Four isoforms of p110 has been found; the alpha, beta, gamma, and the delta subunit. The delta isoform is predominantly expressed in leukocytes and has been shown to interact with p85 and GTP-bound Ras via its SH2/SH3 domain.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Research Areas for PI 3-Kinase p110 delta Antibody (NBP3-24232)

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Blogs on PI 3-Kinase p110 delta.

PI3 Kinase p110 delta - A cell-type specific lipid kinase with essential roles in leukocyte biology
Phosphatidylinositol 3-kinases (PI3Ks) are a group of lipid kinases with important roles in signal transduction. PI3Ks are involved in signal propagation for diverse receptors including tyrosine kinase receptors and G-protein coupled receptors. Cla...  Read full blog post.

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Bioinformatics

Gene Symbol PIK3CD