PI 3-Kinase p110 delta Products

Description

PI3-Kinases (PI3-Ks) are a family of lipid kinases that are implicated in signal transduction. PI3-K consists of two subunits; p85 and p110. The p85 subunit localize PI3-K activity to the plasma membrane while the p110 subunit contains the catalytic domain of PI3-K. Four isoforms of p110 has been found; the alpha, beta, gamma, and the delta subunit. The delta isoform is predominantly expressed in leukocytes and has been shown to interact with p85 and GTP-bound Ras via its SH2/SH3 domain.

Bioinformatics

Entrez	5293 Human
Uniprot	NP_005017 Human O00329 Human
Product By Gene ID	5293
Alternate Names	EC 2.7.1 EC 2.7.1.153 p110D P110DELTA Phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform phosphoinositide-3-kinase C phosphoinositide-3-kinase, catalytic, delta polypeptide PI3K PI3K-delta PI3-kinase p110 subunit delta PI3-kinase subunit delta PtdIns-3-kinase subunit delta PtdIns-3-kinase subunit p110-delta

Research Areas for PI 3-Kinase p110 delta

Find related products by research area and learn more about each of the different research areas below.

Autophagy
mTOR Pathway
Phospho-Specific
Signal Transduction

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PI3 Kinase p110 delta - A cell-type specific lipid kinase with essential roles in leukocyte biology Phosphatidylinositol 3-kinases (PI3Ks) are a group of lipid kinases with important roles in signal transduction. PI3Ks are involved in signal propagation for diverse receptors including tyrosine kinase receptors and G-protein coupled receptors. Cla...    Read more.

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