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Pentraxin 3/TSG-14 Antibody (2B10)

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Western Blot: Pentraxin 3/TSG-14 Antibody (2B10) [H00005806-M02] - PTX3 monoclonal antibody (M02), clone 2B10. Analysis of PTX3 expression in U-2 OS.
Western Blot: Pentraxin 3/TSG-14 Antibody (2B10) [H00005806-M02] - PTX3 monoclonal antibody (M02), clone 2B10. Analysis of PTX3 expression in U-2 OS.
Immunocytochemistry/ Immunofluorescence: Pentraxin 3/TSG-14 Antibody (2B10) [H00005806-M02] - Analysis of monoclonal antibody to PTX3 on HeLa cell. Antibody concentration 10 ug/ml.
Western Blot: Pentraxin 3/TSG-14 Antibody (2B10) [H00005806-M02] - Western Blot analysis of PTX3 expression in PC-12 ( Cat # L012V1 ).
Sandwich ELISA: Pentraxin 3/TSG-14 Antibody (2B10) [H00005806-M02] - Detection limit for recombinant GST tagged PTX3 is approximately 0.03ng/ml as a capture antibody.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF
Clone
2B10
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

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Pentraxin 3/TSG-14 Antibody (2B10) Summary

Description
Quality control test: Antibody Reactive Against Recombinant Protein.
Immunogen
PTX3 (NP_002843, 282 a.a. ~ 380 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. SLWVNGELAATTVEMATGHIVPEGGILQIGQEKNGCCVGGGFDETLAFSGRLTGFNIWDSVLSNEEIRETGGAESCHIRGNIVGWGVTEIQPHGGAQYV
Localization
Secreted
Specificity
PTX3 - pentraxin-related gene, rapidly induced by IL-1 beta
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
PTX3
Purity
IgG purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Sandwich ELISA
  • Western Blot 1:500
Application Notes
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for IF and ELISA.
Publications
Read Publications using H00005806-M02.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
In 1x PBS, pH 7.4
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Pentraxin 3/TSG-14 Antibody (2B10)

  • alpha-induced protein 5
  • pentaxin-related gene, rapidly induced by IL-1 beta, tumor necrosis factor
  • Pentaxin-related protein PTX3
  • Pentraxin 3
  • pentraxin 3, long
  • pentraxin-3
  • pentraxin-related gene, rapidly induced by IL-1 beta
  • pentraxin-related protein PTX3
  • PTX3
  • TNF alpha-induced protein 5
  • TNFAIP5
  • TSG14
  • TSG-14
  • TSG-14pentaxin-related gene, rapidly induced by IL-1 beta
  • Tumor necrosis factor alpha-induced protein 5
  • tumor necrosis factor, alpha-induced protein 5
  • Tumor necrosis factor-inducible gene 14 protein
  • tumor necrosis factor-inducible protein TSG-14

Background

Pentraxin 3 (PTX3) is the prototypic member of the long pentraxin family sharing the C-terminal domain with short pentraxins (C-reactive protein and serum amyloid P component) and containing a unique N-terminal domain. The protein is a soluble pattern recognition receptor and represents a nonredundant component of the humoral innate immunity against selected pathogens. PTX3 is rapidly produced and released at inflammatory sites by diverse cell types including monocytes/macrophages, endothelial cells, vascular smooth muscle cells, fibroblasts, and adipocytes. It interacts with several ligands, including growth factors, extracellular matrix components and selected pathogens. PTX3 has been implicated in vascular damage, angiogenesis, atherosclerosis, and restenosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Pentraxin 3/TSG-14 Antibody (H00005806-M02)(2)


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Bioinformatics

Gene Symbol PTX3
Entrez
OMIM
Uniprot