Novus Biologicals products are now on bio-techne.com

PEDFR/PNPLA2/ATGL Antibody (494702) [Alexa Fluor® 488]

Images

 
Y-79 human retinoblastoma cell line was stained with Mouse Anti-Human PEDF R/PNPLA2 Alexa Fluor® 488-conjugated Monoclonal Antibody (Catalog # FAB5387G, filled histogram) or isotype control antibody (Catalog # ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
494702
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 488

Order Details

PEDFR/PNPLA2/ATGL Antibody (494702) [Alexa Fluor® 488] Summary

Immunogen
E. coli-derived recombinant human PEDF R/PNPLA2
Val162-Thr332
Accession # Q96AD5
Specificity
Detects human PEDF R/PNPLA2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse PEDF R is observed.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
PNPLA2
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 0.25-1 ug/10^6 cells

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes


This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for PEDFR/PNPLA2/ATGL Antibody (494702) [Alexa Fluor® 488]

  • Adipose triglyceride lipase
  • ATGL
  • ATGL1110001C14Rik
  • Calcium-independent phospholipase A2
  • Desnutrin
  • EC 3.1.1.3
  • FP17548
  • IPLA2-zeta
  • patatin-like phospholipase domain containing 2
  • patatin-like phospholipase domain-containing protein 2
  • patatin-like phospholipase domain-containing protein 2-like
  • PEDF R
  • PEDFR
  • PEDF-R
  • Pigment epithelium-derived factor
  • PNPLA2
  • Transport-secretion protein 2
  • transport-secretion protein 2.2
  • triglyceride hydrolase
  • TTS2
  • TTS2.2
  • TTS-2.2
  • TTS2DKFZp667M109

Background

PEDF R (Pigment Epithelium-derived Factor Receptor), also known as PNPLA2, ATGL, TTS2.2, iPLA2 zeta (Calcium-independent Phospholipase A2 zeta) and Desnutrin, is a 82-86 kDa type II transmembrane protein that is a member of the patatin-like phospholipase domain-containing protein family (gene name PNPLA2). PEDF is highly expressed in adipose tissue (both white and brown fat cells), where it the catalyzes formation of diacyglycerol from triglyceride, the transfer of an acyl (CoA-fatty acid) derivative to acyl-glycerol, and releases arachidonic acid from intracellular lipid deposits. It has also been found on retinal pigment epithelium, endothelial cells, hepatocytes, cerebellar granule cells, macrophages, mast cells, ovarian granulosa cells, retinal ganglia neurons and skeletal muscle cells. PEDF R is directly activated by PEDF, and indirectly by  beta 3-AR which promotes CGI-58 association. Human PEDF R shares 85% amino acid (aa) sequence identity with mouse and rat PEDF R within aa 162‑332, the region used as an immunogen.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

DY1177-05
Species: Hu
Applications: ELISA
DVE00
Species: Hu
Applications: ELISA
NB110-37253
Species: Hu, Mu, Rt
Applications: WB
MAB1417
Species: Bv, Hu, Mu
Applications: CyTOF-ready, ICC, IHC, ICFlow
H00051099-M01
Species: Bv, Hu, Pm, Mu, Rt
Applications: ELISA, ICC/IF, IHC, IHC-P, KO, WB
NBP1-88502
Species: Hu
Applications: IHC, IHC-P
NBP2-22106
Species: Hu, Mu, Rt
Applications: IHC, IHC-P, IP, WB
H00008398-D01P
Species: Hu, Mu
Applications: WB
NB110-40760
Species: Fi, Hu, Mu, Po, Rt
Applications: Flow, IMC, ICC/IF, IHC, IHC-P, WB
MAB8306
Species: Hu
Applications: IHC, WB
AF7197
Species: Hu, Mu
Applications: ICC, IHC, WB
NB110-40877
Species: Bv, Hu, Mu, Rt
Applications: Dual ISH-IHC, ICC/IF, IHC, IHC-Fr, IHC-P, Simple Western, WB
NBP1-56853
Species: Hu
Applications: IHC, IHC-P, WB
NB400-114
Species: Ch, Fe, Ha, Hu, Mu, Pl, Po, Pm, Rt
Applications: ICC/IF, IHC, IHC-P, IP, KD, WB
DLP00
Species: Hu
Applications: ELISA
DTSP10
Species: Hu
Applications: ELISA
FAB5387G
Species: Hu
Applications: Flow

Publications for PEDFR/PNPLA2/ATGL Antibody (FAB5387G) (0)

There are no publications for PEDFR/PNPLA2/ATGL Antibody (FAB5387G).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for PEDFR/PNPLA2/ATGL Antibody (FAB5387G) (0)

There are no reviews for PEDFR/PNPLA2/ATGL Antibody (FAB5387G). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for PEDFR/PNPLA2/ATGL Antibody (FAB5387G) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.
mFluor Violet Conjugated Antibodies

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our PEDFR/PNPLA2/ATGL Antibody (494702) [Alexa Fluor® 488] and receive a gift card or discount.

Bioinformatics

Gene Symbol PNPLA2
Uniprot