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PD-L2/B7-DC/PDCD1LG2 Antibody

Images

 
Immunocytochemistry/ Immunofluorescence: PD-L2/B7-DC/PDCD1LG2 Antibody [NBP1-88964] - Staining of human cell line U-2 OS shows localization to cytosol. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: PD-L2/B7-DC/PDCD1LG2 Antibody [NBP1-88964] - Staining of human colon shows moderate cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: PD-L2/B7-DC/PDCD1LG2 Antibody [NBP1-88964] - Staining of human tonsil shows moderate membranous positivity.
Immunohistochemistry-Paraffin: PD-L2/B7-DC/PDCD1LG2 Antibody [NBP1-88964] - Staining of human lung shows moderate cytoplasmic positivity.
Immunohistochemistry-Paraffin: PD-L2/B7-DC/PDCD1LG2 Antibody [NBP1-88964] - Staining of human fallopian tube shows moderate cytoplasmic positivity in glandular cells.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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PD-L2/B7-DC/PDCD1LG2 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: GYPLAEVSWPNVSVPANTSHSRTPEGLYQVTSVLRLKPPPGRNFSCVFWNTHVRELTLASIDLQSQMEPRTHPT
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PDCD1LG2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
PD-L2/B7-DC/PDCD1LG2 Protein (NBP1-88964PEP)
Publications
Read Publications using
NBP1-88964 in the following applications:

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for PD-L2/B7-DC/PDCD1LG2 Antibody

  • B7-DC
  • bA574F11.2
  • Btdc
  • Butyrophilin B7-DC
  • Butyrophilin-like Protein
  • CD273 antigen
  • CD273
  • CD273PD-1 ligand 2
  • MGC142240
  • PD-1-ligand 2
  • PDCD1L2MGC142238
  • PDCD1LG2
  • PDL2
  • PD-L2
  • PDL2B7DC
  • PD-L2PDCD1 ligand 2
  • programmed cell death 1 ligand 2
  • Programmed death ligand 2

Background

B7-DC is also called programmed death ligand 2 (PDL2). It has recently been clustered as CD273. This ligand is a 42 kD member of the immunoglobulin receptor superfamily expressed on a subset of dendritic cells, liver and a small subset of macrophages as well as a few transformed cell lines. B7-DC (CD273) has been reported to be stimulatory on dendritic cells when cross-linked and to inhibit T cell activation upon engaging the PD-1 receptor. B7-DC (CD273) has also been reported to bind to an alternative receptor and to mediate T cell activation through such non-PD1 mediated interactions.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for PD-L2/B7-DC/PDCD1LG2 Antibody (NBP1-88964)(3)

Reviews for PD-L2/B7-DC/PDCD1LG2 Antibody (NBP1-88964) (0)

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

ICC/IF Video Protocol

FAQs for PD-L2/B7-DC/PDCD1LG2 Antibody (NBP1-88964) (0)

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Secondary Antibodies

 

Isotype Controls

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Research Areas for PD-L2/B7-DC/PDCD1LG2 Antibody (NBP1-88964)

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Bioinformatics

Gene Symbol PDCD1LG2