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P2X7/P2RX7 Antibody - BSA Free

Images

 
Western Blot: P2X7/P2RX7 Antibody [NBP2-41300] - Western blot analysis of P2RX7 in 3T3 cell lysate with P2RX7 antibody at (A) 1 and (B) 2 ug/ml.
Immunocytochemistry/ Immunofluorescence: P2X7/P2RX7 Antibody [NBP2-41300] - 3T3 cells with P2RX7 antibody at 5 ug/mL.
Immunocytochemistry/ Immunofluorescence: P2X7/P2RX7 Antibody [NBP2-41300] - Immunofluorescence of P2RX7 in 3T3 cells with P2RX7 antibody at 20 ug/mL.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ELISA, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

Order Details

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P2X7/P2RX7 Antibody - BSA Free Summary

Immunogen
Antibody was raised against a 17 amino acid peptide near the carboxy terminus of human P2RX7. The immunogen is located within the last 50 amino acids of P2RX7. Amino Acid Squence: RWRIRKEFPKSEGQYS
Specificity
Multiple isoforms of P2RX7 are known to exist.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
P2RX7
Purity
Peptide affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence 5-20 ug/mL
  • Western Blot 1-2ug/ml
Theoretical MW
54 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rat: (81%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Peptide affinity purified

Alternate Names for P2X7/P2RX7 Antibody - BSA Free

  • ATP receptor
  • MGC20089
  • P2RX7
  • P2X purinoceptor 7
  • P2X7
  • P2X7P2X7 receptor
  • P2X7R
  • P2Z receptor
  • purinergic receptor P2X, ligand-gated ion channel, 7
  • purinergic receptor P2X7 variant A
  • Purinergic receptor

Background

FUNCTION: Receptor for ATP that acts as a ligand gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells.; Subcellular location: Membrane; Multi-pass membrane protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for P2X7/P2RX7 Antibody (NBP2-41300) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol P2RX7