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P2X7/P2RX7 Antibody [Janelia Fluor® 669]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ELISA, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 669

Order Details

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P2X7/P2RX7 Antibody [Janelia Fluor® 669] Summary

Immunogen
Antibody was raised against a 17 amino acid peptide near the carboxy terminus of human P2RX7. The immunogen is located within the last 50 amino acids of P2RX7. Amino Acid Squence: RWRIRKEFPKSEGQYS
Specificity
Multiple isoforms of P2RX7 are known to exist.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
P2RX7
Purity
Peptide affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rat: (81%)

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Peptide affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for P2X7/P2RX7 Antibody [Janelia Fluor® 669]

  • ATP receptor
  • MGC20089
  • P2RX7
  • P2X purinoceptor 7
  • P2X7
  • P2X7P2X7 receptor
  • P2X7R
  • P2Z receptor
  • purinergic receptor P2X, ligand-gated ion channel, 7
  • purinergic receptor P2X7 variant A
  • Purinergic receptor

Background

FUNCTION: Receptor for ATP that acts as a ligand gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells.; Subcellular location: Membrane; Multi-pass membrane protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for P2X7/P2RX7 Antibody (NBP2-41300JF669) (0)

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Secondary Antibodies

 

Isotype Controls

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Research Areas for P2X7/P2RX7 Antibody (NBP2-41300JF669)

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Bioinformatics

Gene Symbol P2RX7