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OX40/TNFRSF4 Antibody (Ber-ACT35) [Janelia Fluor® 549]

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Product Details

Summary
Reactivity Hu, PmSpecies Glossary
Applications WB, ELISA, Flow, IHC, IP
Clone
Ber-ACT35
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 549

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-62202AF350
Alexa Fluor 405
NBP2-62202AF405
Alexa Fluor 488
NBP2-62202AF488
Alexa Fluor 532
NBP2-62202AF532
Alexa Fluor 594
NBP2-62202AF594
Alexa Fluor 647
NBP2-62202AF647
Alexa Fluor 700
NBP2-62202AF700
Alexa Fluor 750
NBP2-62202AF750
Allophycocyanin
NBP2-62202APC
Biotin
NBP2-62202B
CoraFluor 1
NBP2-62202CL1
DyLight 350
NBP2-62202UV
DyLight 405
NBP2-62202V
DyLight 488
NBP2-62202G
DyLight 550
NBP2-62202R
DyLight 594
NBP2-62202DL594
DyLight 650
NBP2-62202C
DyLight 680
NBP2-62202FR
DyLight 755
NBP2-62202IR
FITC
NBP2-62202F
HRP
NBP2-62202H
Janelia Fluor 525
NBP2-62202JF525
Janelia Fluor 585
NBP2-62202JF585
Janelia Fluor 635
NBP2-62202JF635
Janelia Fluor 646
NBP2-62202JF646
Janelia Fluor 669
NBP2-62202JF669
PE
NBP2-62202PE
PerCP
NBP2-62202PCP
Unconjugated
NBP2-62202
mFluor Violet 450 SE
NBP2-62202MFV450
mFluor Violet 500 SE
NBP2-62202MFV500
mFluor Violet 610 SE
NBP2-62202MFV610
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OX40/TNFRSF4 Antibody (Ber-ACT35) [Janelia Fluor® 549] Summary

Immunogen
HTLV 1-transformed HUT-102 cells
Specificity
The mouse monoclonal antibody Ber-ACT35 (also known as ACT35) recognizes an extracellular epitope of OX40/TNFRSF4, an approximately 50 kDa type I transmembrane glycoprotein expressed on activated T cells.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
TNFRSF4
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for OX40/TNFRSF4 Antibody (Ber-ACT35) [Janelia Fluor® 549]

  • ACT-135
  • ACT35 antigen
  • ACT35ATC35 antigen
  • CD134 antigen
  • CD134
  • Ly-70
  • OX40 cell surface antigen
  • OX40 homologue
  • OX40
  • OX40L receptor
  • OX40lymphoid activation antigene ACT35
  • TAX transcriptionally-activated glycoprotein 1 receptor
  • tax-transcriptionally activated glycoprotein 1 receptor
  • TNFRSF4
  • tumor necrosis factor receptor superfamily member 4
  • tumor necrosis factor receptor superfamily, member 4
  • Txgp1
  • TXGP1L
  • TXGP1LOX40 antigen

Background

The OX40 receptor is also known as CD134, ACT35, and tumor necrosis factor receptor superfamily member 4. This receptor is expressed on activated CD4+ and CD8+ T cells and B cells. The OX40 receptor binds to the OX40 ligand to provide a co-stimulatory signal that is independent of CD28. Blockade of OX40-OX40 ligand interactions has been shown to ameliorate experimental EAE and inflammatory bowel disease, imply that these interactions are important in the pathogenesis of some autoimmune diseases.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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OX40/TNFRSF4
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NBP2-62202JF549
OX40/TNFRSF4 Antibody (Ber-ACT35) [Janelia Fluor® 549]
Species: Hu, Pm
Applications: WB, ELISA, Flow, IHC, IP

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Bioinformatics

Gene Symbol TNFRSF4