Species: Hu
Applications: WB, Flow, IHC, B/N, CyTOF-ready
Host: Sheep Polyclonal
Species: Hu, Pm
Applications: WB, ELISA, Flow, IHC, IP
Host: Mouse Monoclonal
Species: Hu
Applications: WB, ICC/IF, IHC, IP
Host: Rabbit Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Mu
Applications: Bioactivity
Species: Hu
Applications: Bioactivity
Species: Hu
Applications: Bioactivity
Description
The OX40 receptor is also known as CD134, ACT35, and tumor necrosis factor receptor superfamily member 4. This receptor is expressed on activated CD4+ and CD8+ T cells and B cells. The OX40 receptor binds to the OX40 ligand to provide a co-stimulatory signal that is independent of CD28. Blockade of OX40-OX40 ligand interactions has been shown to ameliorate experimental EAE and inflammatory bowel disease, imply that these interactions are important in the pathogenesis of some autoimmune diseases.
Bioinformatics
| Uniprot |
Human
Human
Mouse
|
| Product By Gene ID |
7293 |
| Alternate Names |
- ACT35 antigen
- ACT35ATC35 antigen
- CD134 antigen
- CD134
- OX40 cell surface antigen
- OX40 homologue
- OX40L receptor
- OX40lymphoid activation antigene ACT35
- TAX transcriptionally-activated glycoprotein 1 receptor
- tax-transcriptionally activated glycoprotein 1 receptor
- tumor necrosis factor receptor superfamily member 4
- tumor necrosis factor receptor superfamily, member 4
- TXGP1LOX40 antigen
|
![Western Blot OX40/TNFRSF4 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/OX40_AF3388_Western_Blot_20032.jpg)
![N/A OX40/TNFRSF4 [Biotin]](http://images.novusbio.com/fullsize2/OX40_DY338805_ELISA_2572.jpg)
![Binding Activity OX40/TNFRSF4 [Biotin]](http://images.novusbio.com/fullsize2/avi9969_recombinant-human-ox40-tnfrsf4-his-tag-avi-tag-protein-cf-binding-activity-2942021111448.jpg)
![Flow Cytometry OX40/TNFRSF4 [Alexa Fluor 488]](http://images.novusbio.com/fullsize2/afg3388_recombinant-human-ox40-tnfrsf4-fc-alexa-fluor-488-protein-flow-cytometry-3182021145538.jpg)
![Flow Cytometry OX40/TNFRSF4 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/OX40_AF3388_Flow_Cytometry_8198.jpg)
![Immunohistochemistry OX40/TNFRSF4 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/OX40_AF3388_Immunohistochemistry_21502.jpg)
![Neutralization OX40/TNFRSF4 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/OX40_AF3388_Block_Neutralize_22839.jpg)
![SDS-PAGE OX40/TNFRSF4 [Biotin]](http://images.novusbio.com/fullsize2/avi9969_recombinant-human-ox40-tnfrsf4-his-tag-avi-tag-protein-cf-sds-page-313202111322.jpg)
![SDS-PAGE OX40/TNFRSF4 [Alexa Fluor 488]](http://images.novusbio.com/fullsize2/afg3388_recombinant-human-ox40-tnfrsf4-fc-alexa-fluor-488-protein-sds-page-101020227626.jpg)