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OX40/TNFRSF4 Antibody (443318) [DyLight 350]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, CyTOF-ready
Clone
443318
Clonality
Monoclonal
Host
Rat
Conjugate
DyLight 350

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB3388U-100UG
Alexa Fluor 405
FAB3388V-100UG
Alexa Fluor 488
FAB3388G-100UG
Alexa Fluor 532
FAB3388X
Alexa Fluor 594
FAB3388T-100UG
Alexa Fluor 647
FAB3388R-100UG
Alexa Fluor 700
FAB3388N-100UG
Alexa Fluor 750
FAB3388S-100UG
Allophycocyanin
FAB3388A
Allophycocyanin/Cy7
FAB3388APCCY7
Biotin
FAB3388B
CoraFluor 1
FAB3388CL1
DyLight 405
FAB3388E
DyLight 488
FAB3388K
DyLight 550
FAB3388L
DyLight 594
FAB3388M
DyLight 650
FAB3388W
DyLight 680
FAB3388Y
DyLight 755
FAB3388Z
Fluorescein
FAB3388F
HRP
FAB3388H
Janelia Fluor 525
FAB3388JF525
Janelia Fluor 549
FAB3388I
Janelia Fluor 646
FAB3388J
Janelia Fluor 669
FAB3388JF669
PE/Atto594
FAB3388PEATT594
PE/Cy5.5
FAB3388PECY55
PE/Cy7
FAB3388PECY7
PerCP
FAB3388C
Phycoerythrin
FAB3388P
Unconjugated
MAB3388
mFluor Violet 450 SE
FAB3388MFV450
mFluor Violet 500 SE
FAB3388MFV500
mFluor Violet 610 SE
FAB3388MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB3388
Carrier Free
FAB3388F
Carrier Free
FAB3388P
Carrier Free
MAB3388
Carrier Free
FAB3388A
Carrier Free
MAB3388-SP
Carrier Free
FAB3388V-100UG
Carrier Free
FAB3388U-100UG
Carrier Free
FAB3388T-100UG
Carrier Free
FAB3388S-100UG
Carrier Free
FAB3388R-100UG
Carrier Free
FAB3388N-100UG
Carrier Free
FAB3388G-100UG
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OX40/TNFRSF4 Antibody (443318) [DyLight 350] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human OX40/TNFRSF4
Leu29-Ala216
Accession # P43489
Specificity
Detects human OX40/TNFRSF4 in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human (rh) 4-1BB, rhBAFF R, rhCD27, rhCD30, rhCD40, rhDR3, rhDR6, rhEDAR, rhFAS, rhGITR, rhHVEM, rhLT beta R, rhNGF R, rhRANK, rhRELT, rhTAJ, rhTNF RI, rhTNF RII, rhTRAIL, rhTRAIL R4, rhTRAIL R3, rhTWEAK R, or rhXEDAR is observed.
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
TNFRSF4
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for OX40/TNFRSF4 Antibody (443318) [DyLight 350]

  • ACT-135
  • ACT35 antigen
  • ACT35ATC35 antigen
  • CD134 antigen
  • CD134
  • Ly-70
  • OX40 cell surface antigen
  • OX40 homologue
  • OX40
  • OX40L receptor
  • OX40lymphoid activation antigene ACT35
  • TAX transcriptionally-activated glycoprotein 1 receptor
  • tax-transcriptionally activated glycoprotein 1 receptor
  • TNFRSF4
  • tumor necrosis factor receptor superfamily member 4
  • tumor necrosis factor receptor superfamily, member 4
  • Txgp1
  • TXGP1L
  • TXGP1LOX40 antigen

Background

The OX40 receptor is also known as CD134, ACT35, and tumor necrosis factor receptor superfamily member 4. This receptor is expressed on activated CD4+ and CD8+ T cells and B cells. The OX40 receptor binds to the OX40 ligand to provide a co-stimulatory signal that is independent of CD28. Blockade of OX40-OX40 ligand interactions has been shown to ameliorate experimental EAE and inflammatory bowel disease, imply that these interactions are important in the pathogenesis of some autoimmune diseases.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol TNFRSF4