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NKG2E/KLRC3 Antibody

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Immunohistochemistry: NKG2E/KLRC3 Antibody [NBP2-46867] - Staining of human tonsil shows strong positivity in a subset of cells.
Immunohistochemistry: NKG2E/KLRC3 Antibody [NBP2-46867] - Staining of human tonsil shows strong positivity in a subset of cells.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

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NKG2E/KLRC3 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: NCAMLHVRGLISDQCGSSRIIRRGFIMLTRLVLN
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
KLRC3
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
NKG2E/KLRC3 Recombinant Protein Antigen (NBP2-46867PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for NKG2E/KLRC3 Antibody

  • killer cell lectin-like receptor subfamily C, member 3
  • NK cell receptor E
  • NKG2-E type II integral membrane protein
  • NKG2E
  • NKG2-E-activating NK receptor
  • NKG2ENKG2-E

Background

KLRC3 codes for a protein that works as a receptor for the recognition of MHC molecules by natural killers, and in some cases cytotoxic T-cells. KLRC3 is a gene made up of two isoforms, measuring 240 and 257 amino acids in length, and weighing approximately 27 and 29 kDa respectively. Studies have been done on diseases and disorders relating to this gene including monkeypox. KLRC3 has also been shown to have interactions with KLRD1, TYROBP, HLA-A, and HLA-C in pathways such as the antigen processing and natural killer cell mediated cytotoxicity pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Harnessing Natural Killer Cell Activity for Anti-Tumor Immunotherapy
By Victoria Osinski, PhDWhat’s “Natural” About Natural Killer (NK) Cells?For immunologists, the term cytotoxicity often conjures up images of an army of antigen specific CD8+ T cells deploying to ...  Read full blog post.
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Bioinformatics

Gene Symbol KLRC3
Entrez
Uniprot