Mouse reactivity reported from a verified customer review.
Packaging, Storage & Formulations
Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified
Notes
DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
Alternate Names for NK1R Antibody [DyLight 650]
NK1R
NK-1R
NK1Rneurokinin 1 receptor
NKIR
SPR
SPRsubstance-P receptor
TAC1R
TAC1Rtachykinin 1 receptor (substance P receptor, neurokinin 1 receptor)
tachykinin receptor 1 (substance P receptor; neurokinin-1 receptor)
tachykinin receptor 1NK-1 receptor
TACR1
Background
The tachykinins belong to an evolutionary conserved family of peptide neurotransmitters that share the c-terminal sequence Phe-X-Gly-Leu-Met-NH2 and have an established role in neurotransmission. The mammalian tachykinins include substance P, neurokinin A (NKA) and neurokinin B (NKB) which exert their effects by binding to specific receptors. Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine headache and allergy induced asthma. Three tachykinin receptor types have been characterized, NK-1, NK-2 and NK-3 which have preferential affinities for SP, NKA and NKB respectively. All three receptors share a high degree of sequence homology, have seven transmembrane spanning domains and similar signal transduction mechanisms (e.g. G-protein coupled activation of phospholipase C).
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
FAQs for NK1R Antibody (NB300-119C). (Showing 1 - 1 of 1 FAQ).
We have an inquiry of your product catalog # NB300-119C. Our customer would like to know what is the dilution of the ab for Flow cytometry? Do you have recommend protocol of this application?
The recommended dilution of NB300-119C for flow cytometry is 1:100. Our flow cytometry protocol can be found at this link.
The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.
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