NK1R Antibody (694549)

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

NK1R (Neurokinin-1 receptor), gene name TACR1 (tachykinin receptor-1), is an ~80 kDa 7-transmembrane glycoprotein receptor for the proinflammatory tachykinin neuropeptide, substance P. NK1R is constitutively or inducibly expressed on a wide variety of cells, including monocytes, macrophages, microglia, lymphocytes, neutrophils, mast cells, and neurons. The 407 amino acid (aa) human NK1R contains 89 extracellular aa over multiple segments which collectively share 92% aa identity with corresponding regions of mouse and rat NK1R. A ~50 kDa short isoform that ends at aa 311 lacks almost all of the C-terminal cytoplasmic signaling region. It is the only form expressed in human monocytes and undifferentiated THP-1 cells, and its function appears to differ from the long isoform.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: Western Blot.

Showing Publication 1 - 1 of 1.

Publication using MAB6687	Applications	Species
Sloniecka M, Le Roux S, Boman P, Bystrom B, Zhou Q, Danielson P Expression Profiles of Neuropeptides, Neurotransmitters, and Their Receptors in Human Keratocytes In Vitro and In Situ. PLoS ONE, 2015-07-27;10(7):e0134157. 2015-07-27 [PMID: 26214847] (Western Blot, Human)	Western Blot	Human

Array MAB6687

• NK1R Antibodies
• NK1R Antibody Pack
• NK1R ELISA Kits
• NK1R Lysate
• NK1R Proteins