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NIK/MAP3K14 Antibody

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Western Blot: NIK/MAP3K14 Antibody [NBP1-83414] - Analysis in control (vector only transfected HEK293T lysate) and MAP3K14 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian ...read more
Immunohistochemistry-Paraffin: NIK/MAP3K14 Antibody [NBP1-83414] - Staining of human liver shows negative to very weak positivity in hepatocytes.
Immunohistochemistry-Paraffin: NIK/MAP3K14 Antibody [NBP1-83414] - Staining of human rectum shows strong cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: NIK/MAP3K14 Antibody [NBP1-83414] - Staining of human testis shows moderate to strong cytoplasmic positivity in cells in seminiferous ducts.
Immunohistochemistry-Paraffin: NIK/MAP3K14 Antibody [NBP1-83414] - Staining of human skeletal muscle shows strong cytoplasmic positivity in myocytes.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

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NIK/MAP3K14 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids:SVYKLEAVEKSPVFCGKWEILNDVITKGTAKEGSEAGPAAISIIAQAECENSQEFSPTFSERIFIAGSKQYSQSESLDQIPNNVAHA
Predicted Species
Mouse (92%), Rat (92%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MAP3K14
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
  • Western Blot 0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for NIK/MAP3K14 Antibody

  • EC 2.7.11.25
  • FTDCR1B
  • HS
  • HSNIK
  • HSNIKserine/threonine protein-kinase
  • MAP3K14
  • mitogen-activated protein kinase kinase kinase 14
  • NIK
  • NIKNF-kappa-beta-inducing kinase
  • Serine/threonine-protein kinase NIK

Background

MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14) kinase binds to TRAF2 and stimulates NF-kappaB activity. MAP3K14 is regulated by MAP3K7, RIPK1, TRAF2, TRAF6 and TRAF3. MAP3K14 has been studied in relation to salivary gland cancer, rheumatoid arthritis, t-cell leukemia, ectodermal dysplasia, melanoma and several other diseases and disorders.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol MAP3K14