Western Blot: NCAPD3 Antibody [NB100-1573] - Detection of human CAP-D3 by western blot. Samples: Whole cell lysate (50 ug) from HeLa, 293T, and Jurkat cells prepared using NETN lysis buffer. Antibody: Affinity purified ...read more
Immunoprecipitation: NCAPD3 Antibody [NB100-1573] - Detection of human CAP-D3 by western blot of immunoprecipitates. Samples: Whole cell lysate (1.0 mg per IP reaction; 20% of IP loaded) from 293T cells prepared using ...read more
The immunogen recognized by this antibody maps to a region between residue 1450 and the C-terminus (residue 1507) of human Chromosome-Associated Protein D3 using the numbering given in entry NP_056076.1 (GeneID 23310).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
NCAPD3
Purity
Immunogen affinity purified
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CAP-D3 is a subunit of the heteropentameric condensin II complex. Condensin participates in the condensation of chromosomes during cell division by facilitating positive DNA supercoiling and knotting by topoisomerase I and II, and aids in the proper segregation of sister chromatids. In the condensin II complex CAP-D3 is regulated by protein phosphatase 2A (PP2A) and may participate in centromere resolution. Alternate designations of CAP-D3 include condensin-II complex subunit D3, Non-SMC condensin II complex subunit D3, hCAP-D3, CAPD3, hcp-6, hHCP-6, FLJ42888, MGC1046871, and KIAA0056.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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