MYH Antibody Summary
Immunogen
This antibody was generated by immunizing rabbits with a synthetic peptide corresponding to amino acids 531-546 of human MYH.
Localization
Nuclear
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MUTYH
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Applications/Dilutions
Dilutions
Immunocytochemistry/ Immunofluorescence 18 ug/ml. Use reported in scientific literature Immunohistochemistry 1:10- 1:2000. Use reported in scientific literature Western Blot 2 ug/ml
Application Notes
Western Blot: Predicted molecular weight: 65.5 kDa.
Control
Publications
Read Publications using NB600-1032 in the following applications:
Packaging, Storage & Formulations
Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS containing 0.05% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein G purified
Alternate Names for MYH Antibody
Background
MYH is the eukaryotic homolog to the E. coli protein MutY. It was first identified in HeLa cells and nicks DNA replication errors, specifically A/G mismatches.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Publications for MYH Antibody (NB600-1032)(7)
We have publications tested in 3 confirmed species: Mouse, Rat, Bacteria.
We have publications tested in 2 applications: ICC/IF, WB.
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Showing Publications 1 -
7 of 7.
Publications using NB600-1032
Applications
Species
Fang M, Ohman Strickland PA, Kang HG, Zarbl, H. Uncoupling genotoxic stress responses from circadian control increases susceptibility to mammary carcinogenesis. Oncotarget. 2017-05-16 [PMID: 28427145] (WB, Rat)
WB
Rat
Turco E, Ventura I, Minoprio A et al. Understanding the role of the Q338H MUTYH variant in oxidative damage repair. Nucleic Acids Res 2013-03-04 [PMID: 23460202] (WB, Mouse)
WB
Mouse
Zaika E, Wei J, Yin D et al. p73 protein regulates DNA damage repair. FASEB J. 2011-09-02 [PMID: 21891782]
D'Agostino VG, Minoprio A, Torreri P et al. Functional analysis of MUTYH mutated proteins associated with familial adenomatous polyposis DNA Repair (Amst) 2010-06-04 [PMID: 20418187] (WB, Bacteria)
WB
Bacteria
Molatore S, Russo MT, D'Agostino VG et al. MUTYH mutations associated with familial adenomatous polyposis: functional characterization by a mammalian cell-based assay. Hum Mutat 2010-02-01 [PMID: 19953527] (ICC/IF, WB, Mouse)
ICC/IF, WB
Mouse
Bonde, P, Gao, D, Chen, L, Miyashita, T, Montgomery, E, Harmon, J W, Wei, C. Duodenal Reflux Leads to Down Regulation of DNA Mismatch Repair Pathway in an Animal Model of Esophageal Cancer, . 83, 433-440. 2007-01-01 [PMID: 17257966]
Gao, D et al. Oxidative DNA damage DNA repair enzyme expression inversely related in murine models of fatty liver disease. Am J Physiol: Gastrointestinal Liver Physiology 287:1070-1077. 2004-01-01 [PMID: 15231485]
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Product General Protocols
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Control Lysate(s)
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