MYH Products

Description

MYH encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Bioinformatics

Uniprot	AAH03178 Human NM_001048174 Human NP_001041636.1 Human NP_001041638 Human NP_036354.1 Human Q9UIF7 Human
Product By Gene ID	4595
Alternate Names	EC 3.2.2 EC 3.2.2.- EC 3.2.2.31 hMYH MGC4416 MutY homolog MUTYH Muyth MYH MYHA/G-specific adenine DNA glycosylase

Research Areas for MYH

Find related products by research area and learn more about each of the different research areas below.

Base Excision Repair
Cancer
DNA Repair