Cytochrome P450 1A2 Antibody (OTI8F1)

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 application: ICC/IF.

Showing Publication 1 - 1 of 1.

Publication using NBP2-02563	Applications	Species
Wuensch T, Heucke N, Wizenty J et al. Hepatic CYP1A2 activity in liver tumors and the implications for preoperative volume-function analysis American Journal of Physiology-Gastrointestinal and Liver Physiology 2019-05-01 [PMID: 30869529] (ICC/IF)	ICC/IF

Array NBP2-02563

• Cytochrome P450 1A2 Antibodies
• Cytochrome P450 1A2 ELISA Kits
• Cytochrome P450 1A2 Lysate
• Cytochrome P450 1A2 Proteins