MuSK Antibody

Communication between cells is often mediated by receptors on the surface of the target cell that are triggered by specific ligands released by other cells. Receptor tyrosine kinase activity is strictly regulated by the binding of the appropriate ligand to the extracellular active site of the receptor. These types of receptors play a role critical in the growth and differentiation of different cell types. A muscle specific kinase recently identified, termed MUSK for muscle-specific kinase, and has been shown to be specifically expressed in the muscle cells within the neuromuscular junction. MUSK has been shown to be part of the agrin signaling complex and plays an important role in the development and architectural maintenance of the neuromuscular junction.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publication using NB120-5619	Applications	Species
Louit A, Beaudet MJ, Gros-Louis F, Berthod F Tissue-engineered in vitro modeling of the impact of Schwann cells in amyotrophic lateral sclerosis Biotechnology and bioengineering 2022-03-15 [PMID: 35289393]

Array NB120-5619

• MuSK Antibodies
• MuSK Proteins and Enzymes