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MuSK Antibody (PSH03-51)

Images

 
Western Blot: MuSK Antibody (PSH03-51) [NBP3-32620] - Western blot analysis of MuSK on different lysates with Rabbit anti-MuSK antibody (NBP3-32620) at 1/2,000 dilution. Lane 1: Human brain tissue lysate Lane 2: Mouse ...read more
Immunohistochemistry: MuSK Antibody (PSH03-51) [NBP3-32620] - Immunohistochemical analysis of paraffin-embedded human skeletal muscle tissue with Rabbit anti-MuSK antibody (NBP3-32620) at 1/2,000 dilution. The section ...read more

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC
Clone
PSH03-51
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

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MuSK Antibody (PSH03-51) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
Recombinant protein within human MuSK aa 1-516 / 869. (Uniprot: O15146)
Localization
Postsynaptic cell membrane.
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
MUSK
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:500-1:2000
  • Western Blot 1:2000
Theoretical MW
97 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH7.4), 0.1% BSA and 40% Glycerol
Preservative
0.05% Sodium Azide
Concentration
1 mg/ml
Purity
Protein A purified

Alternate Names for MuSK Antibody (PSH03-51)

  • EC 2.7.10
  • EC 2.7.10.1
  • MGC126323
  • MGC126324
  • muscle, skeletal, receptor tyrosine kinase
  • MuSK
  • skeletal receptor tyrosine-protein kinase

Background

Intercellular communication is often mediated by receptors on the surface of one cell that recognize and are activated by specific protein ligands released by other cells. Members of one class of cell surface receptors, receptor tyrosine kinases (RTKs), are characterized by having a cytoplasmic domain containing intrinsic tyrosine kinase activity. This kinase activity is regulated by the binding of a cognate ligand to the extracellular portion of the receptor. DeChiara et al. (1996) [PubMed 8653786] noted that the RTKs, known to be expressed in cell type-specific fashions, play a role critical for the growth and differentiation of those cell types. For example, members of the neural-specific TRK family that recognize nerve growth factor are absolutely required for the survival and development of discrete neuronal subpopulations, and the receptor tyrosine kinases TIE1 (MIM 600222) and TIE2 (MIM 600221) play a critical role in the development of normal blood vessels.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for MuSK Antibody (NBP3-32620) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol MUSK