This antibody was developed against Recombinant Protein corresponding to amino acids: SSLPFSVEALMSDKKPPKEASPLPAESASAGATLRPLLLSGHGAREAHSPGPLVKPFETASVKSENSEDGAAWMQEPGRYSPPPRHTSPTTCTLRKHKTNRKP
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MSX2
Purity
Immunogen affinity purified
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Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified
Alternate Names for MSX2 Antibody
CRS2
CRS2parietal foramina 1
FPP
Homeobox protein Hox-8
homeobox protein MSX-2
Hox8
HOX8msh homeobox homolog 2 (Drosophila)
msh (Drosophila) homeo box homolog 2
msh homeo box 2
msh homeobox 2
msh homeobox homolog 2
MSH
MSX2
PFM
PFM1
Background
Msx2/Hox8 encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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