| Pouxvielh, K;Marotel, M;Drouillard, A;Villard, M;Moreews, M;Bossan, A;Poiget, M;Khoryati, L;Benezech, S;Fallone, L;Hamada, S;Rousseaux, N;Picq, L;Rocca, Y;Berton, A;Teixeira, M;Mathieu, AL;Ainouze, M;Hasan, U;Fournier, A;Thaunat, O;Marçais, A;Walzer, T; Tumor-induced natural killer cell dysfunction is a rapid and reversible process uncoupled from the expression of immune checkpoints Science advances 2024-08-30 [PMID: 39196934] (Mouse) |
|
Mouse |
| Pinzan, CF;Valero, C;de Castro, PA;da Silva, JL;Earle, K;Liu, H;Horta, MAC;Kniemeyer, O;Krüger, T;Pschibul, A;Cömert, DN;Heinekamp, T;Brakhage, AA;Steenwyk, JL;Mead, ME;Hermsdorf, N;Filler, SG;da Rosa-Garzon, NG;Delbaje, E;Bromley, MJ;Cabral, H;Diehl, C;Angeli, CB;Palmisano, G;Ibrahim, AS;Rinker, DC;Sauters, TJC;Steffen, K;Gumilang, A;Rokas, A;Gago, S;Dos Reis, TF;Goldman, GH; Aspergillus fumigatus conidial surface-associated proteome reveals factors for fungal evasion and host immunity modulation Nature microbiology 2024-08-27 [PMID: 39191887] (Mouse) |
|
Mouse |
| Gabele, L;Bochow, I;Rieke, N;Sieben, C;Michaelsen-Preusse, K;Hosseini, S;Korte, M; H7N7 viral infection elicits pronounced, sex-specific neuroinflammatory responses in vitro Frontiers in cellular neuroscience 2024-08-07 [PMID: 39171200] (Mouse) |
|
Mouse |
| Ohm, M;Hosseini, S;Lonnemann, N;He, W;More, T;Goldmann, O;Medina, E;Hiller, K;Korte, M; The potential therapeutic role of itaconate and mesaconate on the detrimental effects of LPS-induced neuroinflammation in the brain Journal of neuroinflammation 2024-08-20 [PMID: 39164713] (Mouse) |
|
Mouse |
| Sun, L;Apweiler, M;Tirkey, A;Klett, D;Normann, C;Dietz, GPH;Lehner, MD;Fiebich, BL; Anti-Neuroinflammatory Effects of Ginkgo biloba Extract EGb 761 in LPS-Activated BV2 Microglial Cells International journal of molecular sciences 2024-07-25 [PMID: 39125680] (Mouse) |
|
Mouse |
| Mendoza, M;Ballesteros, A;Rendon-Correa, E;Tonk, R;Warren, J;Snow, AL;Stowell, SR;Blois, SM;Dveksler, G; Modulation of galectin-9 mediated responses in monocytes and T-cells by pregnancy-specific glycoprotein 1 The Journal of biological chemistry 2024-08-07 [PMID: 39121996] (Mouse) |
|
Mouse |
| Xu, J;Pickard, JM;Núñez, G; FDA-approved disulfiram inhibits the NLRP3 inflammasome by regulating NLRP3 palmitoylation Cell reports 2024-08-07 [PMID: 39116210] (Mouse) |
|
Mouse |
| Map Schuh, C;Ezquer, F;Mamani, S;Campodónico, PR;Cárcamo, C;Martinez-Gómez, F;Aburto, I;Ezquer, M;Morales, B;Olivares, B; A Natural deep eutectic solvent as an effective material for dual debridement and antibiofilm effects in chronic wound treatment International journal of pharmaceutics 2024-08-03 [PMID: 39103063] (Mouse) |
|
Mouse |
| Huang, Q;Yang, G;Tang, C;Dou, B;Hu, Y;Liu, H;Wu, X;Zhang, H;Wang, H;Xu, L;Yang, XD;Xu, Y;Zheng, Y; Rujin Jiedu decoction protects against influenza virus infection by modulating gut microbiota Heliyon 2024-07-15 [PMID: 39071618] (Mouse) |
|
Mouse |
| Abarikwu, SO;Coimbra, JLP;Campolina-Silva, G;Rocha, ST;Costa, VV;Lacerda, SMSN;Costa, GMJ; Acute effects of atrazine on the immunoexpressions of Sertoli and germ cells molecular markers, cytokines, chemokines, and sex hormones levels in mice testes and epididymides Chemosphere 2024-07-15 [PMID: 39019188] (Mouse) |
|
Mouse |
| Rizzo, GP;Sanches, RC;Chavero, C;Bianchi, DS;Apuzzo, E;Herrera, SE;Agazzi, ML;Keitelman, IA;Trevani, AS;Oliveira, SC;Azzaroni, O;Smaldini, PL;Docena, GH; Poly(allylamine)-tripolyphosphate polymeric nanoparticle as an NLRP3-dependent systemic adjuvant for the vaccine development bioRxiv : the preprint server for biology 2024-07-04 [PMID: 39005275] (Mouse) |
|
Mouse |
| Katsoulis, O;Toussaint, M;Jackson, MM;Mallia, P;Footitt, J;Mincham, KT;Meyer, GFM;Kebadze, T;Gilmour, A;Long, M;Aswani, AD;Snelgrove, RJ;Johnston, SL;Chalmers, JD;Singanayagam, A; Neutrophil extracellular traps promote immunopathogenesis of virus-induced COPD exacerbations Nature communications 2024-07-09 [PMID: 38982052] (Mouse) |
|
Mouse |
| Pourhashem, Z;Nourani, L;Pirahmadi, S;Yousefi, H;J Sani, J;Raz, A;Zakeri, S;Dinparast Djadid, N;Abouie Mehrizi, A; Malaria transmission blocking activity of Anopheles stephensi alanyl aminopeptidase N antigen formulated with MPL, CpG, and QS21 adjuvants PloS one 2024-07-05 [PMID: 38968270] (Mouse) |
|
Mouse |
| Yow, SJ;Rosli, SN;Hutchinson, PE;Chen, KW; Differential signalling requirements for RIPK1-dependent pyroptosis in neutrophils and macrophages Cell death & disease 2024-07-04 [PMID: 38965211] (Mouse, Transgenic Mouse) |
|
Mouse, Transgenic Mouse |
| Lim, PN;Cervantes, MM;Pham, LK;Doherty, S;Tufts, A;Dubey, D;Mai, D;Aderem, A;Diercks, AH;Rothchild, AC; Absence of c-Maf and IL-10 enables Type I IFN enhancement of innate responses to low-dose LPS in alveolar macrophages bioRxiv : the preprint server for biology 2024-05-26 [PMID: 38826239] (Mouse) |
|
Mouse |
| Salesse, L;Duval, A;Sauvanet, P;Da Silva, A;Barnich, N;Godfraind, C;Dalmasso, G;Nguyen, HTT; ATG16L1 in myeloid cells limits colorectal tumor growth in ApcMin/+ mice infected with colibactin-producing Escherichia coli via decreasing inflammasome activation Autophagy 2024-05-31 [PMID: 38818900] (Mouse) |
|
Mouse |
| Flores-Valdez, MA;Peterson, EJR;Aceves-Sánchez, MJ;Baliga, NS;Morita, YS;Sparks, IL;Saini, DK;Yadav, R;Lang, R;Mata-Espinosa, D;León-Contreras, JC;Hernández-Pando, R; Comparison of the transcriptome, lipidome, and c-di-GMP production between BCG?BCG1419c and BCG, with Mincle- and Myd88-dependent induction of proinflammatory cytokines in murine macrophages Scientific reports 2024-05-24 [PMID: 38789479] (Mouse, Transgenic Mouse) |
|
Mouse, Transgenic Mouse |
| Zabala, AS;Conforti, RA;Delsouc, MB;Filippa, V;Montt-Guevara, MM;Giannini, A;Simoncini, T;Vallcaneras, SS;Casais, M; Estetrol Inhibits Endometriosis Development in an In Vivo Murine Model Biomolecules 2024-05-15 [PMID: 38785987] (Mouse) |
|
Mouse |
| Alves, M;Gil, B;Villegas-Salmerón, J;Salari, V;Martins-Ferreira, R;Arribas Blázquez, M;Menéndez Méndez, A;Da Rosa Gerbatin, R;Smith, J;de Diego-Garcia, L;Conte, G;Sierra-Marquez, J;Merino Serrais, P;Mitra, M;Fernandez Martin, A;Wang, Y;Kesavan, J;Melia, C;Parras, A;Beamer, E;Zimmer, B;Heiland, M;Cavanagh, B;Parcianello Cipolat, R;Morgan, J;Teng, X;Prehn, JHM;Fabene, PF;Bertini, G;Artalejo, AR;Ballestar, E;Nicke, A;Olivos-Oré, LA;Connolly, NMC;Henshall, DC;Engel, T; Opposing effects of the purinergic P2X7 receptor on seizures in neurons and microglia in male mice Brain, behavior, and immunity 2024-05-20 [PMID: 38777288] (Transgenic Mouse) |
|
Transgenic Mouse |
| Achi, SC;McGrosso, D;Tocci, S;Ibeawuchi, SR;Sayed, IM;Gonzalez, DJ;Das, S; Proteome profiling identifies a link between the mitochondrial pathways and host-microbial sensor ELMO1 following Salmonella infection bioRxiv : the preprint server for biology 2024-05-03 [PMID: 38746404] (Human) |
|
Human |
| Lee, J;Kim, MY;Kim, HJ;Choi, WS;Kim, HS; Impaired autophagy in myeloid cells aggravates psoriasis-like skin inflammation through the IL-1?/CXCL2/neutrophil axis Cell & bioscience 2024-05-04 [PMID: 38704587] (Transgenic Mouse) |
|
Transgenic Mouse |
| Moon, S;Han, S;Jang, IH;Ryu, J;Rha, MS;Cho, HJ;Yoon, SS;Nam, KT;Kim, CH;Park, MS;Seong, JK;Lee, WJ;Yoon, JH;Chung, YW;Ryu, JH; Airway epithelial CD47 plays a critical role in inducing influenza virus-mediated bacterial super-infection Nature communications 2024-04-30 [PMID: 38693120] (Mouse) |
|
Mouse |
| Sun, L;Wilke Saliba, S;Apweiler, M;Akmermer, K;Herlan, C;Grathwol, C;de Oliveira, ACP;Normann, C;Jung, N;Bräse, S;Fiebich, BL; Anti-Neuroinflammatory Effects of a Macrocyclic Peptide-Peptoid Hybrid in Lipopolysaccharide-Stimulated BV2 Microglial Cells International journal of molecular sciences 2024-04-18 [PMID: 38674048] (Mouse) |
|
Mouse |
| Wang, X;Cheng, Z;Tai, W;Shi, M;Ayazi, M;Liu, Y;Sun, L;Yu, C;Fan, Z;Guo, B;He, X;Sun, D;Young, W;Ren, Y; Targeting foamy macrophages by manipulating ABCA1 expression to facilitate lesion healing in the injured spinal cord Brain, behavior, and immunity 2024-04-16 [PMID: 38636566] (Mouse) |
|
Mouse |
| Krishnamohan, M;Kaplanov, I;Maudi-Boker, S;Yousef, M;Machluf-Katz, N;Cohen, I;Elkabets, M;Titus, J;Bersudsky, M;Apte, RN;Voronov, E;Braiman, A; Tumor Cell-Associated IL-1? Affects Breast Cancer Progression and Metastasis in Mice through Manipulation of the Tumor Immune Microenvironment International journal of molecular sciences 2024-04-02 [PMID: 38612760] (Mouse, Transgenic Mouse) |
|
Mouse, Transgenic Mouse |
| Wang, Y;Gao, JZ;Sakaguchi, T;Maretzky, T;Gurung, P;Narayanan, NS;Short, S;Xiong, Y;Kang, Z; LRRK2 G2019S Promotes Colon Cancer Potentially via LRRK2-GSDMD Axis-Mediated Gut Inflammation Cells 2024-03-23 [PMID: 38607004] (Transgenic Mouse) |
|
Transgenic Mouse |
| Zhang, N;Zhang, J;Yang, Y;Shan, H;Hou, S;Fang, H;Ma, M;Chen, Z;Tan, L;Xu, D; A palmitoylation-depalmitoylation relay spatiotemporally controls GSDMD activation in pyroptosis Nature cell biology 2024-03-27 [PMID: 38538834] (Mouse) |
|
Mouse |
| Dai, F;Hu, C;Li, X;Zhang, Z;Wang, H;Zhou, W;Wang, J;Geng, Q;Dong, Y;Tang, C; Cav3.2 channel regulates cerebral ischemia/reperfusion injury: a promising target for intervention Neural regeneration research 2024-11-01 [PMID: 38526284] (Mouse) |
|
Mouse |
| Anees, F;Montoya, DA;Pisetsky, DS;Payne, CK; DNA corona on nanoparticles leads to an enhanced immunostimulatory effect with implications for autoimmune diseases Proceedings of the National Academy of Sciences of the United States of America 2024-03-12 [PMID: 38442162] (Mouse) |
|
Mouse |
| Kraiem, M;Ben Hamouda, S;Eleroui, M;Ajala, M;Feki, A;Dghim, A;Boujhoud, Z;Bouhamed, M;Badraoui, R;Pujo, JM;Essafi-Benkhadir, K;Kallel, H;Ben Amara, I; Anti-Inflammatory and Immunomodulatory Properties of a Crude Polysaccharide Derived from Green Seaweed Halimeda tuna: Computational and Experimental Evidences Marine drugs 2024-02-11 [PMID: 38393056] (Mouse) |
|
Mouse |
| Pereira, M;Ramalho, T;Andrade, WA;Durso, DF;Souza, MC;Fitzgerald, KA;Golenbock, DT;Silverman, N;Gazzinelli, RT; The IRAK1/IRF5 axis initiates IL-12 response by dendritic cells and control of Toxoplasma gondii infection Cell reports 2024-02-15 [PMID: 38367238] (Mouse) |
|
Mouse |
| Kim, MY;Jeong, B;Lee, GS;Jeon, H;Yang, YM;Yang, H;Han, YH; Panaxydol extracted from Panax ginseng inhibits NLRP3 inflammasome activation to ameliorate NASH-induced liver injury International immunopharmacology 2024-01-22 [PMID: 38262161] (Mouse) |
|
Mouse |
| Zou, Z;Obernuefemann, CLP;Singh, P;Pinkner, JS;Xu, W;Nye, TM;Dodson, KW;Almqvist, F;Hultgren, SJ;Caparon, MG; Dihydrothiazolo ring-fused 2-pyridone antimicrobial compounds treat Streptococcus pyogenes skin and soft tissue infection bioRxiv : the preprint server for biology 2024-01-03 [PMID: 38260261] (Mouse) |
|
Mouse |
| Sluiter, TJ;Tillie, RJHA;de Jong, A;de Bruijn, JBG;Peters, HAB;van de Leijgraaf, R;Halawani, R;Westmaas, M;Starink, LIW;Quax, PHA;Sluimer, JC;de Vries, MR; Myeloid PHD2 Conditional Knockout Improves Intraplaque Angiogenesis and Vascular Remodeling in a Murine Model of Venous Bypass Grafting Journal of the American Heart Association 2024-01-23 [PMID: 38258662] (Transgenic Mouse) |
|
Transgenic Mouse |
| Su, G;Huang, S;Jiang, S;Chen, L;Yang, F;Liu, Z;Wang, G;Huang, J; Porcine ?-Defensin 114: Creating a Dichotomous Response to Inflammation International journal of molecular sciences 2024-01-13 [PMID: 38256090] (Mouse) |
|
Mouse |
| Li, XM;Yang, Y;Jiang, FQ;Hu, G;Wan, S;Yan, WY;He, XS;Xiao, F;Yang, XM;Guo, X;Lu, JH;Yang, XQ;Chen, JJ;Ye, WL;Liu, Y;He, K;Duan, HX;Zhou, YJ;Gan, WJ;Liu, F;Wu, H; Histone lactylation inhibits RAR? expression in macrophages to promote colorectal tumorigenesis through activation of TRAF6-IL-6-STAT3 signaling Cell reports 2024-01-19 [PMID: 38245869] (Mouse) |
|
Mouse |
| Li, Z;Zou, X;Lu, R;Wan, X;Sun, S;Wang, S;Qu, Y;Zhang, Y;Li, Z;Yang, L;Fang, S; Arsenic trioxide alleviates atherosclerosis by inhibiting CD36-induced endocytosis and TLR4/NF-?B-induced inflammation in macrophage and ApoE-/- mice International immunopharmacology 2024-01-17 [PMID: 38237221] (Mouse) |
|
Mouse |
| Liu, Y;Kors, L;Butter, LM;Stokman, G;Claessen, N;Zuurbier, CJ;Girardin, SE;Leemans, JC;Florquin, S;Tammaro, A; NLRX1 Prevents M2 Macrophage Polarization and Excessive Renal Fibrosis in Chronic Obstructive Nephropathy Cells 2023-12-21 [PMID: 38201227] (Mouse) |
|
Mouse |
| Caparon, M;Xu, W;Bradstreet, T;Zou, Z;Hickerson, S;Zhou, Y;He, H;Edelson, B; Reprogramming Short-Chain Fatty Acid Metabolism Mitigates Tissue Damage for Streptococcus pyogenes Necrotizing Skin Infection Research square 2023-12-23 [PMID: 38196634] (Mouse) |
|
Mouse |
| De, M;Sukla, S;Bharatiya, S;Keshri, S;Roy, DG;Roy, S;Dutta, D;Saha, S;Ejazi, SA;Ravichandiran, V;Ali, N;Chatterjee, M;Chinnaswamy, S; IFN-?3 is induced by Leishmania donovani and can inhibit parasite growth in cell line models but not in the mouse model, while it shows a significant association with leishmaniasis in humans Infection and immunity 2024-01-09 [PMID: 38193711] (Mouse) |
|
Mouse |
| Nakajima, S;Demers, G;Machuca-Parra, AI;Pour, ZD;Bairamian, D;Bouyakdan, K;Fisette, A;Kabahizi, A;Robb, J;Rodaros, D;Laurent, C;Ferreira, G;Arbour, N;Alquier, T;Fulton, S; Central activation of the fatty acid sensor GPR120 suppresses microglia reactivity and alleviates sickness- and anxiety-like behaviors Journal of neuroinflammation 2023-12-19 [PMID: 38111048] (Mouse) |
|
Mouse |
| Morais, MÍ;Braga, AV;Silva, RRL;Barbosa, BCM;Costa, SOAM;Rodrigues, FF;Melo, ISF;Matos, RC;Carobin, NV;Sabino, AP;Coelho, MM;Machado, RR; Metformin inhibits paclitaxel-induced mechanical allodynia by activating opioidergic pathways and reducing cytokines production in the dorsal root ganglia and thalamus Cytokine 2023-12-14 [PMID: 38101167] (Mouse) |
|
Mouse |
| Zhu, W;Han, L;Wu, Y;Tong, L;He, L;Wang, Q;Yan, Y;Pan, T;Shen, J;Song, Y;Shen, Y;Zhu, Q;Zhou, J; Keratin 15 protects against cigarette smoke-induced epithelial mesenchymal transformation by MMP-9 Respiratory research 2023-11-25 [PMID: 38007424] (Transgenic Mouse, Mouse) |
|
Transgenic Mouse, Mouse |
| Chuang, WH;Pislyagin, E;Lin, LY;Menchinskaya, E;Chernikov, O;Kozhemyako, V;Gorpenchenko, T;Manzhulo, I;Chaikina, E;Agafonova, I;Silchenko, A;Avilov, S;Stonik, V;Tzou, SC;Aminin, D;Wang, YM; Holothurian triterpene glycoside cucumarioside A2-2 induces macrophages activation and polarization in cancer immunotherapy Cancer cell international 2023-11-24 [PMID: 38001420] (Mouse) |
|
Mouse |
| Lopez-Rodriguez, AB;Murray, CL;Kealy, J;Towns, C;Roche, A;Nazmi, A;Doran, M;Lowry, JP;Cunningham, C; Hyperthermia elevates brain temperature and improves behavioural signs in animal models of autism spectrum disorder Molecular autism 2023-11-15 [PMID: 37968722] (Mouse) |
|
Mouse |
| Pereira, RDD;Rabelo, RAN;Oliveira, NFM;Porto, SLT;Andrade, ACDSP;Queiroz-Junior, CM;Barbosa, CLN;de Souza-Costa, LP;Santos, FRDS;Oliveira, FBR;da Silva, BLV;Umezu, HL;Ferreira, R;da Silva, GSF;Cruz, JS;Teixeira, MM;Costa, VV;Machado, FS; A 5-Lipoxygenase Inhibitor, Zileuton, Modulates Host Immune Responses and Improves Lung Function in a Model of Severe Acute Respiratory Syndrome (SARS) Induced by Betacoronavirus Viruses 2023-10-04 [PMID: 37896826] (Mouse) |
|
Mouse |
| Leinardi, R;Petriglieri, JR;Pochet, A;Yakoub, Y;Lelong, M;Lescoat, A;Turci, F;Lecureur, V;Huaux, F; Distinct Pro-Inflammatory Mechanisms Elicited by Short and Long Amosite Asbestos Fibers in Macrophages International journal of molecular sciences 2023-10-13 [PMID: 37894824] (Mouse, Transgenic Mouse) |
|
Mouse, Transgenic Mouse |
| Huang, HC;Lee, PN;Huang, WC;Yang, HY; Partial Replacement of Diet with Dehulled Adlay Ameliorates Hepatic Steatosis, Inflammation, Oxidative Stress, and Gut Dysbiosis in Rats with Nonalcoholic Fatty Liver Disease Nutrients 2023-10-16 [PMID: 37892450] (Rat) |
|
Rat |
| Firth, W;Robb, JL;Stewart, D;Pye, KR;Bamford, R;Oguro-Ando, A;Beall, C;Ellacott, KL; Regulation of astrocyte metabolism by mitochondrial translocator protein 18kDa bioRxiv : the preprint server for biology 2023-10-02 [PMID: 37873215] (Human) |
|
Human |
| Uemura, M;Maeshige, N;Yamaguchi, A;Ma, X;Matsuda, M;Nishimura, Y;Hasunuma, T;Inoue, T;Yan, J;Wang, J;Kondo, H;Fujino, H; Electrical stimulation facilitates NADPH production in pentose phosphate pathway and exerts an anti-inflammatory effect in macrophages Scientific reports 2023-10-19 [PMID: 37857669] (Mouse) |
|
Mouse |
| Russo, S;Kwiatkowski, M;Wolters, JC;Gerding, A;Hermans, J;Govorukhina, N;Bischoff, R;Melgert, BN; Effects of lysine deacetylase inhibitor treatment on LPS responses of alveolar-like macrophages Journal of leukocyte biology 2023-10-09 [PMID: 37811856] (Mouse) |
|
Mouse |
| Guo, ZF;Tongmuang, N;Li, C;Zhang, C;Hu, L;Capreri, D;Zuo, MX;Summer, R;Sun, J; Inhibiting endothelial cell Mst1 attenuates acute lung injury in mice bioRxiv : the preprint server for biology 2023-09-29 [PMID: 37808846] (Mouse) |
|
Mouse |
| Alchawoosh, A;Hashimoto, K;Kawashima, N;Noda, S;Nozaki, K;Okiji, T; Hydraulic calcium silicate-based root canal sealers mitigate proinflammatory cytokine synthesis and promote osteogenesis in vitro Journal of dental sciences 2023-10-01 [PMID: 37799856] (Mouse) |
|
Mouse |
| Goldman, G;Valero, C;Pinzan, C;de Castro, P;van Rhijn, N;Earle, K;Liu, H;Horta, MA;Kniemeyer, O;Kruger, T;Pschibul, A;Coemert, D;Heinekamp, T;Brakhage, A;Steenwyk, J;Mead, M;Rokas, A;Filler, S;da Rosa-Garzon, N;Delbaje, E;Bromley, M;Angeli, C;Palmisano, G;Ibrahim, A;Gago, S;Reis, TD; A phylogenetic approach to explore the Aspergillus fumigatus conidial surface-associated proteome and its role in pathogenesis Research square 2023-09-18 [PMID: 37790311] (Mouse) |
|
Mouse |
| Wong, MP;Juan, EYW;Chelluri, SS;Wang, P;Pahmeier, F;Castillo-Rojas, B;Blanc, SF;Biering, SB;Vance, RE;Harris, E; The Inflammasome Pathway is Activated by Dengue Virus Non-structural Protein 1 and is Protective During Dengue Virus Infection bioRxiv : the preprint server for biology 2023-09-21 [PMID: 37790301] (Mouse) |
|
Mouse |
| Ribeiro, R;Silva, EG;Moreira, FC;Gomes, GF;Cussat, GR;Silva, BSR;da Silva, MCM;de Barros Fernandes, H;de Sena Oliveira, C;de Oliveira Guarnieri, L;Lopes, V;Ferreira, CN;de Faria, AMC;Maioli, TU;Ribeiro, FM;de Miranda, AS;Moraes, GSP;de Oliveira, ACP;Vieira, LB; Chronic hyperpalatable diet induces impairment of hippocampal-dependent memories and alters glutamatergic and fractalkine axis signaling Scientific reports 2023-09-29 [PMID: 37773430] (Mouse) |
|
Mouse |
| Gruol, DL;Calderon, D;Huitron-Resendiz, S;Cates-Gatto, C;Roberts, AJ; Impact of Elevated Brain IL-6 in Transgenic Mice on the Behavioral and Neurochemical Consequences of Chronic Alcohol Exposure Cells 2023-09-19 [PMID: 37759527] (Mouse) |
|
Mouse |
| Joo, MK;Shin, YJ;Kim, DH; Cefaclor causes vagus nerve-mediated depression-like symptoms with gut dysbiosis in mice Scientific reports 2023-09-19 [PMID: 37726354] (Mouse) |
|
Mouse |
| Fechtner, S;Allen, BE;Chriswell, ME;Jubair, WK;Robertson, CE;Kofonow, JN;Frank, DN;Holers, VM;Kuhn, KA; 3,3-dimethyl-1-butanol and its metabolite 3,3-dimethylbutyrate ameliorate collagen-induced arthritis independent of choline trimethylamine lyase activity Research square 2023-09-05 [PMID: 37720032] (Mouse) |
|
Mouse |
| Kaneki, M;Ohira, C;Takahashi, M;Iwashita, N;Takagi, Y;Nagane, M;Uchiyama, J;Fukuyama, T; Therapeutic potential of ozone water treatment in alleviating atopic dermatitis symptoms in mouse models: Exploring its bactericidal and direct anti-inflammatory properties International immunopharmacology 2023-09-14 [PMID: 37716162] (Mouse) |
|
Mouse |
| Vichare, R;Crelli, C;Liu, L;McCallin, R;Cowan, A;Stratimirovic, S;Herneisey, M;Pollock, JA;Janjic, JM; Folate-conjugated near-infrared fluorescent perfluorocarbon nanoemulsions as theranostics for activated macrophage COX-2 inhibition Scientific reports 2023-09-14 [PMID: 37709807] (Mouse) |
|
Mouse |
| Valero, C;Pinzan, CF;de Castro, PA;van Rhijn, N;Earle, K;Liu, H;Horta, MAC;Kniemeyer, O;Krüger, T;Pschibul, A;Coemert, DN;Heinekamp, T;Brakhage, AA;Steenwyk, JL;Mead, ME;Rokas, A;Filler, SG;da Rosa-Garzon, NG;Cabral, H;Deljabe, E;Bromley, MJ;Angeli, CB;Palmisano, G;Ibrahim, AS;Gago, S;Dos Reis, TF;Goldman, GH; A phylogenetic approach to explore the Aspergillus fumigatus conidial surface-associated proteome and its role in pathogenesis bioRxiv : the preprint server for biology 2023-08-22 [PMID: 37662192] (Mouse) |
|
Mouse |
| Su, N;Villicana, C;Zhang, C;Lee, J;Sinha, S;Yang, A;Yang, F; Aspirin synergizes with mineral particle-coated macroporous scaffolds for bone regeneration through immunomodulation Theranostics 2023-08-15 [PMID: 37649612] (Mouse) |
|
Mouse |
| Schädel, P;Wichmann-Costaganna, M;Czapka, A;Gebert, N;Ori, A;Werz, O; Short-Term Caloric Restriction and Subsequent Re-Feeding Compromise Liver Health and Associated Lipid Mediator Signaling in Aged Mice Nutrients 2023-08-21 [PMID: 37630850] (Mouse) |
|
Mouse |
| Hollifield, IE;Motyka, NI;Fernando, KA;Bitoun, JP; Heat-Labile Enterotoxin Decreases Macrophage Phagocytosis of Enterotoxigenic Escherichia coli Microorganisms 2023-08-21 [PMID: 37630681] (Mouse) |
|
Mouse |
| Das, B;Madhubala, D;Mahanta, S;Patra, A;Puzari, U;Khan, MR;Mukherjee, AK; A Novel Therapeutic Formulation for the Improved Treatment of Indian Red Scorpion (Mesobuthus tamulus) Venom-Induced Toxicity-Tested in Caenorhabditis elegans and Rodent Models Toxins 2023-08-14 [PMID: 37624261] (Mouse) |
|
Mouse |
| Bar-Oz, M;Martini, MC;Alonso, MN;Meir, M;Lore, NI;Miotto, P;Riva, C;Angala, SK;Xiao, J;Masiello, CS;Misiakou, MA;Sun, H;Moy, JK;Jackson, M;Johansen, HK;Cirillo, DM;Shell, SS;Barkan, D; The small non-coding RNA B11 regulates multiple facets of Mycobacterium abscessus virulence PLoS pathogens 2023-08-01 [PMID: 37603560] (Mouse) |
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Mouse |
| Torazza, C;Provenzano, F;Gallia, E;Cerminara, M;Balbi, M;Bonifacino, T;Tessitore, S;Ravera, S;Usai, C;Musante, I;Puliti, A;Van Den Bosch, L;Jafar-Nejad, P;Rigo, F;Milanese, M;Bonanno, G; Genetic Downregulation of the Metabotropic Glutamate Receptor Type 5 Dampens the Reactive and Neurotoxic Phenotype of Adult ALS Astrocytes Cells 2023-07-27 [PMID: 37566031] (Mouse) |
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Mouse |
| Yang, Y;Gao, ZF;Hou, GG;Meng, QG;Hou, Y; Discovery of anti-neuroinflammatory agents from 1,4,5,6-tetrahydrobenzo[2,3]oxepino[4,5-d]pyrimidin-2-amine derivatives by regulating microglia polarization European journal of medicinal chemistry 2023-11-05 [PMID: 37544188] (Mouse) |
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Mouse |
| Matamoros-Recio, A;Merino, J;Gallego-Jiménez, A;Conde-Alvarez, R;Fresno, M;Martín-Santamaría, S; Immune evasion through Toll-like receptor 4: The role of the core oligosaccharides from alpha 2-Proteobacteria atypical lipopolysaccharides Carbohydrate polymers 2023-10-15 [PMID: 37479429] (Mouse) |
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Mouse |
| Micevic, G;Daniels, A;Flem-Karlsen, K;Park, K;Talty, R;McGeary, M;Mirza, H;Blackburn, HN;Sefik, E;Cheung, JF;Hornick, NI;Aizenbud, L;Joshi, NS;Kluger, H;Iwasaki, A;Bosenberg, MW;Flavell, RA; IL-7R licenses a population of epigenetically poised memory CD8+ T cells with superior antitumor efficacy that are critical for melanoma memory Proceedings of the National Academy of Sciences of the United States of America 2023-07-25 [PMID: 37459511] (Mouse) |
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Mouse |
| Wang, Y;Gao, JZ;Sakaguchi, T;Maretzky, T;Gurung, P;Short, S;Xiong, Y;Kang, Z; LRRK2 G2019S promotes the development of colon cancer via modulating intestinal inflammation bioRxiv : the preprint server for biology 2023-06-30 [PMID: 37425755] (Mouse) |
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Mouse |
| Lee, CK;Oliveira, LVN;Akalin, A;Specht, CA;Lourenco, D;Gomez, CL;Ramirez-Ortiz, ZG;Wang, JP;Levitz, SM; Dysregulated Pulmonary Inflammatory Responses Exacerbate the Outcome of Secondary Aspergillosis Following Influenza bioRxiv : the preprint server for biology 2023-06-30 [PMID: 37425745] (Mouse) |
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Mouse |
| Nyariki, JN;Kimani, NM;Kibet, PS;Kinuthia, GK;Isaac, AO; Coenzyme Q10 exhibits anti-inflammatory and immune-modulatory thereby decelerating the occurrence of experimental cerebral malaria Molecular and biochemical parasitology 2023-06-27 [PMID: 37385350] (Mouse) |
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Mouse |
| Merriman, JA;Xu, W;Caparon, MG; Central carbon flux controls growth/damage balance for Streptococcus pyogenes PLoS pathogens 2023-06-29 [PMID: 37384800] (Mouse) |
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Mouse |
| Pinto, EP;da Costa, SOAM;D'Haese, C;Nysten, B;Machado, FP;Rocha, LM;de Souza, TM;Beloqui, A;Machado, RR;Araújo, RS; Poly-?-caprolactone nanocapsules loaded with copaiba essential oil reduce inflammation and pain in mice International journal of pharmaceutics 2023-06-17 [PMID: 37336298] (Mouse) |
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Mouse |
| Hopkin, SJ;Pezhman, L;Begum, J;Kavanagh, D;McGettrick, HM;Iqbal, AJ;Chimen, M; Aging modulates homeostatic leukocyte trafficking to the peritoneal cavity in a sex-specific manner Journal of leukocyte biology 2023-06-13 [PMID: 37309034] (Mouse) |
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Mouse |
| Torres, L;Camila Gonçalves Miranda, M;Dantas Martins, V;Caixeta, F;de Almeida Oliveira, M;Martins Trindade, L;Carvalho de Assis, H;Nascimento, V;Pinheiro Rosa, N;Gomes, E;Oliveira Almeida, S;Marquet, F;Genser, L;Marcelin, G;Clément, K;Russo, M;Maria Caetano Faria, A;Uceli Maioli, T; Obesity-induced hyperglycemia impairs oral tolerance induction and aggravates food allergy Mucosal immunology 2023-06-09 [PMID: 37302712] (Mouse) |
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Mouse |
| Su, P;Wu, M;Yin, X;Li, M;Li, Y;Bai, M;Wang, B;Xu, E; Modified Xiaoyao San reverses lipopolysaccharide-induced depression-like behavior through suppressing microglia M1 polarization via enhancing autophagy involved in PI3K/Akt/mTOR pathway in mice Journal of ethnopharmacology 2023-05-30 [PMID: 37263314] (Mouse) |
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Mouse |
| Kim, TW; Fisetin, an Anti-Inflammatory Agent, Overcomes Radioresistance by Activating the PERK-ATF4-CHOP Axis in Liver Cancer International journal of molecular sciences 2023-05-22 [PMID: 37240422] (Mouse) |
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Mouse |
| Chen, W;Zhu, CS;Qiang, X;Chen, S;Li, J;Wang, P;Tracey, KJ;Wang, H; Development of Procathepsin L (pCTS-L)-Inhibiting Lanosterol-Carrying Liposome Nanoparticles to Treat Lethal Sepsis International journal of molecular sciences 2023-05-12 [PMID: 37239992] (Mouse) |
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Mouse |
| Tarkany Basting, R;Henrique Napimoga, M;Ant�nio Trindade Silva, C;Ballassini Abdalla, H;Campos Durso, B;Henrique Barboza Martins, L;de Abreu Cavalcanti, H;Hammock, BD;Trindade Clemente-Napimoga, J; Soluble epoxide hydrolase inhibitor blockage microglial cell activation in subnucleus caudalis in a persistent model of arthritis International immunopharmacology 2023-05-23 [PMID: 37230034] (Mouse) |
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Mouse |
| Li, C;Ture, SK;Nieves-Lopez, B;Blick-Nitko, SK;Maurya, P;Livada, AC;Stahl, TJ;Kim, M;Pietropaoli, AP;Morrell, CN; Thrombocytopenia Independently Leads to Monocyte Immune Dysfunction bioRxiv : the preprint server for biology 2023-05-12 [PMID: 37214993] (Mouse) |
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Mouse |
| Hamadi, N;Beegam, S;Zaaba, NE;Elzaki, O;Altamimi, MA;Nemmar, A; Neuroinflammation, Oxidative Stress, Apoptosis, Microgliosis and Astrogliosis in the Cerebellum of Mice Chronically Exposed to Waterpipe Smoke Biomedicines 2023-04-06 [PMID: 37189722] (Mouse) |
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Mouse |
| Gschwandtner, M;Gammage, AN;Deligne, C;Mies, LFM;Domaingo, A;Murdamoothoo, D;Loustau, T;Schwenzer, A;Derler, R;Carapito, R;Koch, M;M�rgelin, M;Orend, G;Kungl, AJ;Midwood, KS; Investigating Chemokine-Matrix Networks in Breast Cancer: Tenascin-C Sets the Tone for CCL2 International journal of molecular sciences 2023-05-06 [PMID: 37176074] (Mouse) |
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Mouse |
| YJ Chen, GN Li, XJ Li, LX Wei, MJ Fu, ZL Cheng, Z Yang, GQ Zhu, XD Wang, C Zhang, JY Zhang, YP Sun, H Saiyin, J Zhang, WR Liu, WW Zhu, KL Guan, Y Xiong, Y Yang, D Ye, LL Chen Targeting IRG1 reverses the immunosuppressive function of tumor-associated macrophages and enhances cancer immunotherapy Science Advances, 2023-04-28;9(17):eadg0654. 2023-04-28 [PMID: 37115931] (Mouse) |
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Mouse |
| T Tominaga, J Huang, S Wang, M Noguchi, Y Tong, M Asano-Orit, K Suzuki Collagen-Derived Dipeptides and Amino Acids Have Immunomodulatory Effects in M1-Differentiated RAW264.7 Cells and PBMC International Journal of Molecular Sciences, 2023-04-08;24(8):. 2023-04-08 [PMID: 37108094] (Mouse) |
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Mouse |
| P Schädel, A Czapka, N Gebert, ID Jacobsen, A Ori, O Werz Metabololipidomic and proteomic profiling reveals aberrant macrophage activation and interrelated immunomodulatory mediator release during aging Aging Cell, 2023-04-26;0(0):e13856. 2023-04-26 [PMID: 37101405] (Mouse) |
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Mouse |
| H Liu, S Wang, L Gong, Y Shen, F Xu, Y Wang, L Hu, L Zhu SIRT6 ameliorates LPS-induced apoptosis and tight junction injury in ARDS through the ERK1/2 pathway and autophagy International Journal of Medical Sciences, 2023-03-05;20(5):581-594. 2023-03-05 [PMID: 37082736] (Mouse) |
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Mouse |
| C Zhang, ZF Guo, W Liu, K Kazama, L Hu, X Sun, L Wang, H Lee, L Lu, XF Yang, R Summer, J Sun PIMT is a novel and potent suppressor of endothelial activation Elife, 2023-04-18;12(0):. 2023-04-18 [PMID: 37070640] (Mouse) |
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Mouse |
| H Noda, J Suzuki, Y Matsuoka, A Matsumoto, M Kuwahara, Y Kamei, Y Takada, M Yamashita The histone demethylase Utx controls CD8+ T-cell-dependent antitumor immunity via epigenetic regulation of the effector function Cancer Science, 2023-04-17;0(0):. 2023-04-17 [PMID: 37068788] (ELISA, Mouse) |
ELISA |
Mouse |
| M Baran, C Feriotti, A McGinley, SR Carlile, Z Jiang, R Calderon-G, A Dumigan, J Sá-Pessoa, CE Sutton, J Kearney, RM McLoughlin, KHG Mills, KA Fitzgerald, JA Bengeochea, AG Bowie PYHIN protein IFI207 regulates cytokine transcription and IRF7 and contributes to the establishment of K. pneumoniae infection Cell Reports, 2023-04-04;42(4):112341. 2023-04-04 [PMID: 37018072] (Mouse) |
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Mouse |
| D Levy, SN Abadchi, N Shababi, MR Ravari, NH Pirolli, C Bergeron, A Obiorah, F Mokhtari-E, S Gheshlaghi, JM Abraham, IM Smith, E Powsner, T Solomon, JW Harmon, SM Jay Induced pluripotent stem cell-derived extracellular vesicles promote wound repair in a diabetic mouse model via an anti-inflammatory immunomodulatory mechanism bioRxiv : the preprint server for biology, 2023-03-23;0(0):. 2023-03-23 [PMID: 36993554] (Mouse) |
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Mouse |
| G Feigelman, E Simanovich, P Brockmeyer, MA Rahat Knocking-Down CD147/EMMPRIN Expression in CT26 Colon Carcinoma Forces the Cells into Cellular and Angiogenic Dormancy That Can Be Reversed by Interactions with Macrophages Biomedicines, 2023-03-02;11(3):. 2023-03-02 [PMID: 36979746] (Mouse) |
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Mouse |
| P De Cicco, G Ercolano, C Sirignano, V Rubino, D Rigano, A Ianaro, C Formisano Chamomile essential oils exert anti-inflammatory effects involving human and murine macrophages: Evidence to support a therapeutic action Journal of ethnopharmacology, 2023-03-21;0(0):116391. 2023-03-21 [PMID: 36948263] (Mouse) |
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Mouse |
| S Devi, M Indramohan, E Jäger, J Carriere, LH Chu, L de Almeida, DR Greaves, C Stehlik, A Dorfleutne CARD-only proteins regulate in�vivo inflammasome responses and ameliorate gout Cell Reports, 2023-03-16;42(3):112265. 2023-03-16 [PMID: 36930645] (Mouse) |
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Mouse |
| VP Skulachev, MY Vyssokikh, BV Chernyak, OA Averina, AA Andreev-An, RA Zinovkin, KG Lyamzaev, MV Marey, MV Egorov, OJ Frolova, DB Zorov, MV Skulachev, VA Sadovnichi Mitochondrion-targeted antioxidant SkQ1 prevents rapid animal death caused by highly diverse shocks Scientific Reports, 2023-03-15;13(1):4326. 2023-03-15 [PMID: 36922552] (Mouse) |
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Mouse |
| JH Park, JH Kim, JY Shin, ES Kang, BO Cho Anti-inflammatory effects of Peucedanum japonicum Thunberg leaves extract in Lipopolysaccharide-stimulated RAW264.7�cells Journal of ethnopharmacology, 2023-03-10;309(0):116362. 2023-03-10 [PMID: 36907479] (Mouse) |
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Mouse |
| A Hooftman, CG Peace, DG Ryan, EA Day, M Yang, AF McGettrick, M Yin, EN Montano, L Huo, JE Toller-Kaw, V Zecchini, TAJ Ryan, A Bolado-Car, AM Casey, HA Prag, ASH Costa, G De Los San, M Ishimori, DJ Wallace, S Venuturupa, E Nikitopoul, N Frizzell, C Johansson, A Von Kriegs, MP Murphy, C Jefferies, C Frezza, LAJ O'Neill Macrophage fumarate hydratase restrains mtRNA-mediated interferon production Nature, 2023-03-08;615(7952):490-498. 2023-03-08 [PMID: 36890227] (Mouse, Transgenic Mouse) |
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Mouse, Transgenic Mouse |
| PR Johnsen, C Pinna, L Mattio, MB Strube, M Di Nunzio, S Iametti, S Dallavalle, A Pinto, H Frøkiær Investigation of the Effects of Monomeric and Dimeric Stilbenoids on Bacteria-Induced Cytokines and LPS-Induced ROS Formation in Bone Marrow-Derived Dendritic Cells International Journal of Molecular Sciences, 2023-02-01;24(3):. 2023-02-01 [PMID: 36769058] (Mouse) |
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Mouse |
| LU Teufel, MG Netea, FL van de Vee, CA Dinarello, LAB Joosten, RJW Arts Opposing Effects of Interleukin-36gamma and Interleukin-38 on Trained Immunity International Journal of Molecular Sciences, 2023-01-24;24(3):. 2023-01-24 [PMID: 36768634] (Mouse, Transgenic Mouse) |
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Mouse, Transgenic Mouse |
| P Jordan, A Costa, E Specker, O Popp, A Volkamer, R Piske, T Obrusnik, S Kleissle, K Stuke, A Rex, M Neuenschwa, JP von Kries, M Nazare, P Mertins, H Kettenmann, SA Wolf Small molecule inhibiting microglial nitric oxide release could become a potential treatment for neuroinflammation PLoS ONE, 2023-02-06;18(2):e0278325. 2023-02-06 [PMID: 36745631] (Mouse) |
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Mouse |
| A Oun, E Hoeksema, A Soliman, F Brouwer, F García-Rey, H Pots, M Trombetta-, A Kortholt, AM Dolga Characterization of Lipopolysaccharide Effects on LRRK2 Signaling in RAW Macrophages International Journal of Molecular Sciences, 2023-01-13;24(2):. 2023-01-13 [PMID: 36675159] (Mouse) |
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Mouse |
| M Hureau, L Portier, M Prin, P de Nadai, J Balsamelli, A Tsicopoulo, D Mathieu, P Lassalle, B Grigoriu, A Gaudet, N De Freitas Evaluation of Endocan as a Treatment for Acute Inflammatory Respiratory Failure Cells, 2023-01-07;12(2):. 2023-01-07 [PMID: 36672192] (Mouse) |
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Mouse |
| TTT Nguyen, YH Choi, WK Lee, Y Ji, E Chun, YH Kim, JE Lee, HS Jung, JH Suh, S Kim, M Jin Tryptophan-dependent and -independent secretions of tryptophanyl- tRNA synthetase mediate innate inflammatory responses Cell Reports, 2022-12-30;42(1):111905. 2022-12-30 [PMID: 36640342] (Mouse) |
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Mouse |
| TFR Costa, A Goundry, A Morrot, DJ Grab, JC Mottram, APCA Lima Trypanosoma brucei rhodesiense Inhibitor of Cysteine Peptidase (ICP) Is Required for Virulence in Mice and to Attenuate the Inflammatory Response International Journal of Molecular Sciences, 2022-12-30;24(1):. 2022-12-30 [PMID: 36614101] (Mouse) |
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Mouse |
| H Yu, Z Zhang, G Li, Y Feng, L Xian, F Bakhsh, D Xu, C Xu, T Vong, B Wu, FM Selaru, F Wan, M Donowitz, GW Wong Adipokine C1q/Tumor necrosis factor- Related Protein 3 (CTRP3) Attenuates Intestinal Inflammation via Sirtuin 1 / NF-kappaB Signaling Cellular and Molecular Gastroenterology and Hepatology, 2022-12-30;0(0):. 2022-12-30 [PMID: 36592863] (Mouse) |
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Mouse |
| Y Lin, X Cui, Q Cao, R Bi, Y Liu, D Jing, C Yue, Q Zhao, Y Wang, S Liu, Y Su, K Formoso, S Susperregu, L Birnbaumer, M Freichel, Y Yang, L You, X Gao TRPC absence induces pro-inflammatory macrophages and gut microbe disorder, sensitizing mice to colitis International immunopharmacology, 2022-12-31;115(0):109655. 2022-12-31 [PMID: 36592529] (Mouse) |
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Mouse |
| DC Sarver, C Xu, LM Velez, S Aja, AE Jaffe, MM Seldin, RH Reeves, GW Wong Dysregulated systemic metabolism in a Down syndrome mouse model Molecular Metabolism, 2022-12-29;68(0):101666. 2022-12-29 [PMID: 36587842] (Mouse) |
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Mouse |
| FP Veras, GA Publio, BM Melo, DS Prado, T Norbiato, NT Cecilio, C Hiroki, LEA Damasceno, R Jung, JE Toller-Kaw, TV Martins, SF Assunção, D Lima, MG Alves, GV Vieira, LA Tavares, ALR Alves-Reze, SH Karbach, HI Nakaya, TM Cunha, CS Souza, FQ Cunha, KU Sales, A Waisman, JC Alves-Filh Pyruvate kinase M2 mediates IL-17 signaling in keratinocytes driving psoriatic skin inflammation Cell Reports, 2022-12-27;41(13):111897. 2022-12-27 [PMID: 36577385] (Mouse) |
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Mouse |
| YS Hwang, HJ Cho, ES Park, J Lim, HR Yoon, JT Kim, SR Yoon, H Jung, YK Choe, YH Kim, CH Lee, YT Kwon, BY Kim, HG Lee KLK6/PAR1 Axis Promotes Tumor Growth and Metastasis by Regulating Cross-Talk between Tumor Cells and Macrophages Cells, 2022-12-16;11(24):. 2022-12-16 [PMID: 36552865] (Mouse) |
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Mouse |
| K Chen, LY Cheong, Y Gao, Y Zhang, T Feng, Q Wang, L Jin, E Honoré, KSL Lam, W Wang, X Hui, A Xu Adipose-targeted triiodothyronine therapy counteracts obesity-related metabolic complications and atherosclerosis with negligible side effects Nature Communications, 2022-12-20;13(1):7838. 2022-12-20 [PMID: 36539421] (Mouse) |
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Mouse |
| ARD Santos, TF Fraga-Silv, DF Almeida-Do, AC Finatto, C Marchetti, MI Andrade, OS Arruda, MSP Arruda, J Venturini Is the production of reactive oxygen and nitrogen species by macrophages associated with better infectious control in female mice with experimentally disseminated and pulmonary mucormycosis? PLoS ONE, 2022-12-15;17(12):e0270071. 2022-12-15 [PMID: 36520787] (Mouse) |
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Mouse |
| J Yim, J Lee, S Yi, JY Koo, S Oh, H Park, SS Kim, MA Bae, J Park, SB Park Phenotype-based screening rediscovered benzopyran-embedded microtubule inhibitors as anti-neuroinflammatory agents by modulating the tubulin-p65 interaction Experimental & Molecular Medicine, 2022-12-12;54(12):2200-2209. 2022-12-12 [PMID: 36509830] (Mouse) |
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Mouse |
| Z Zhang, R Venditti, L Ran, Z Liu, K Vivot, A Schürmann, JS Bonifacino, MA De Matteis, R Ricci Distinct changes in endosomal composition promote NLRP3 inflammasome activation Nature Immunology, 2022-11-28;0(0):. 2022-11-28 [PMID: 36443515] (Mouse) |
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Mouse |
| PF Kinoshita, AM Orellana, DZ Andreotti, GA de Souza, NP de Mello, L de Sá Lima, EM Kawamoto, C Scavone Consequences of the Lack of TNFR1 in Ouabain Response in the Hippocampus of C57BL/6J Mice Biomedicines, 2022-11-15;10(11):. 2022-11-15 [PMID: 36428505] (Mouse) |
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Mouse |
| JS Park, SC Yang, HY Jeong, SY Lee, JG Ryu, JW Choi, HY Kang, SM Kim, SH Hwang, ML Cho, SH Park EC-18 prevents autoimmune arthritis by suppressing inflammatory cytokines and osteoclastogenesis Arthritis Research & Therapy, 2022-11-17;24(1):254. 2022-11-17 [PMID: 36397156] (Mouse) |
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Mouse |
| CS Rigazio, N Mariz-Pont, EP Caballero, FN Penas, NB Goren, MH Santamaría, RS Corral Involvement of glycoinositolphospholipid from Trypanosoma cruzi and macrophage migration inhibitory factor in proinflammatory mechanisms promoting cardiovascular injury mechanisms promoting cardiovascular inflammation tThe combined action of glycoinositolphospholipid from Trypanosoma cruzi and macrophage migration inhibitory factor increases proinflammatory mediator production by cardiomyocytes and vascular endothelial cells Microbial pathogenesis, 2022-11-12;0(0):105881. 2022-11-12 [PMID: 36379373] (Mouse) |
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Mouse |
| I Chiulan, DM Panaitescu, A Serafim, ER Radu, G Ioni??, V R?di?oiu, AR Gabor, CA Nicolae, M Ghiurea, DD Baciu Sponges from Plasma Treated Cellulose Nanofibers Grafted with Poly(ethylene glycol)methyl Ether Methacrylate Polymers, 2022-11-04;14(21):. 2022-11-04 [PMID: 36365713] (Mouse) |
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Mouse |
| S Giofrè, A Renda, S Sesana, B Formicola, B Vergani, BE Leone, V Denti, G Paglia, S Groppuso, V Romeo, L Muzio, A Balboni, A Menegon, A Antoniou, A Amenta, D Passarella, P Seneci, S Pellegrino, F Re Dual Functionalized Liposomes for Selective Delivery of Poorly Soluble Drugs to Inflamed Brain Regions Pharmaceutics, 2022-11-07;14(11):. 2022-11-07 [PMID: 36365220] (Mouse) |
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Mouse |
| Z Pan, B Mao, Q Zhang, X Tang, B Yang, J Zhao, S Cui, H Zhang Postbiotics Prepared Using Lactobacillus paracasei CCFM1224 Prevent Nonalcoholic Fatty Liver Disease by Modulating the Gut Microbiota and Liver Metabolism International Journal of Molecular Sciences, 2022-11-04;23(21):. 2022-11-04 [PMID: 36362307] (Mouse) |
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Mouse |
| S Singh, IA Shaikh, SS More, MH Mahnashi, HM Almohaimee, M El-Sherbin, MM Ghoneim, A Umar, HK Soni, H Agrawal, BA Mannasaheb, AA Khan, UM Muddapur, SMS Iqubal Blockage of KHSRP-NLRP3 by MCC950 Can Reverse the Effect of Manganese-Induced Neuroinflammation in N2a Cells and Rat Brain International Journal of Molecular Sciences, 2022-10-30;23(21):. 2022-10-30 [PMID: 36362011] (Mouse, Rat) |
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Mouse, Rat |
| MSJ Mangan, F Gorki, K Krause, A Heinz, A Pankow, T Ebert, D Jahn, K Hiller, V Hornung, M Maurer, FI Schmidt, R Gerhard, E Latz Transcriptional licensing is required for Pyrin inflammasome activation in human macrophages and bypassed by mutations causing familial Mediterranean fever PloS Biology, 2022-11-07;20(11):e3001351. 2022-11-07 [PMID: 36342970] (Human) |
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Human |
| S Rotem, E Bar-Haim, U Elia, H Cohen, S Lazar, O Cohen, T Chitlaru, Y Gal A Novel Approach to Vaccine Development: Concomitant Pathogen Inactivation and Host Immune Stimulation by Peroxynitrite Vaccines, 2022-09-22;10(10):. 2022-09-22 [PMID: 36298458] (Mouse) |
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Mouse |
| V Mulens-Ari, A Nicolás-Bo, F Carn, F Gazeau Cationic Polyethyleneimine (PEI)-Gold Nanocomposites Modulate Macrophage Activation and Reprogram Mouse Breast Triple-Negative MET-1 Tumor Immunological Microenvironment Pharmaceutics, 2022-10-19;14(10):. 2022-10-19 [PMID: 36297669] (Mouse) |
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Mouse |
| Y Jiang, Y Yang, Y Hu, R Yang, J Huang, Y Liu, Y Wu, S Li, C Ma, F Humphries, B Wang, X Wang, Z Hu, S Yang Gasdermin D restricts anti-tumor immunity during PD-L1 checkpoint blockade Cell Reports, 2022-10-25;41(4):111553. 2022-10-25 [PMID: 36288704] (Mouse) |
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Mouse |
| S Li, Y Fang, Y Zhang, M Song, X Zhang, X Ding, H Yao, M Chen, Y Sun, J Ding, Q Wang, M Lu, G Wu, G Hu Microglial NLRP3 inflammasome activates neurotoxic astrocytes in depression-like mice Cell Reports, 2022-10-25;41(4):111532. 2022-10-25 [PMID: 36288697] (Mouse) |
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Mouse |
| AE Pottash, D Levy, A Jeyaram, L Kuo, SM Kronstadt, W Chao, SM Jay Combinatorial microRNA Loading into Extracellular Vesicles for Increased Anti-Inflammatory Efficacy Non-coding RNA, 2022-10-21;8(5):. 2022-10-21 [PMID: 36287123] (Mouse) |
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Mouse |
| H Wang, Y Li, Z Yue, Y Liu, Q Chen, D Hu, J Han Adipose-Derived Stem Cell Exosomes Inhibit Hypertrophic Scaring Formation by Regulating Th17/Treg Cell Balance BioMed Research International, 2022-10-12;2022(0):9899135. 2022-10-12 [PMID: 36277890] (Mouse) |
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Mouse |
| J Liu, L Shi, W Huang, Z Zheng, X Huang, Y Su Homoharringtonine Attenuates Dextran Sulfate Sodium-Induced Colitis by Inhibiting NF-kappaB Signaling Mediators of Inflammation, 2022-09-29;2022(0):3441357. 2022-09-29 [PMID: 36211988] (Mouse) |
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Mouse |
| J Wang, Q Zhu, R Li, J Zhang, X Ye, X Li YAP1 protects against septic liver injury via ferroptosis resistance Cell & bioscience, 2022-10-01;12(1):163. 2022-10-01 [PMID: 36182901] (Mouse) |
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Mouse |
| JK Allen, TC Sutherland, AR Prater, CG Geoffroy, JP Pellois In vivo peptide-based delivery of a gene-modifying enzyme into cells of the central nervous system Science Advances, 2022-09-28;8(39):eabo2954. 2022-09-28 [PMID: 36170360] (Mouse) |
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Mouse |
| N Milad, M Pineault, F Tremblay, J Routhier, A Lechasseur, MJ Beaulieu, S Aubin, MC Morissette Smoking status impacts treatment efficacy in smoke-induced lung inflammation: A pre-clinical study Frontiers in Pharmacology, 2022-09-07;13(0):971238. 2022-09-07 [PMID: 36160400] (Mouse) |
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Mouse |
| L Pérez-Regi, J Guzmán-Cal, N Oberhauser, C Punzón, B Balogh, JR Pedro, E Falomir, A Nurisso, P Mátyus, JC Menéndez, B de Andrés, M Fresno, S Martín-San Small Molecules as Toll-like Receptor 4 Modulators Drug and In-House Computational Repurposing Biomedicines, 2022-09-19;10(9):. 2022-09-19 [PMID: 36140427] (Mouse) |
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Mouse |
| N Millet, NV Solis, D Aguilar, MS Lionakis, RT Wheeler, N Jendzjowsk, M Swidergall IL-23 signaling prevents ferroptosis-driven renal immunopathology during candidiasis Nature Communications, 2022-09-22;13(1):5545. 2022-09-22 [PMID: 36138043] (Mouse) |
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Mouse |
| D Emin, YP Zhang, E Lobanova, A Miller, X Li, Z Xia, H Dakin, DI Sideris, JYL Lam, RT Ranasinghe, A Kouli, Y Zhao, S De, TPJ Knowles, M Vendruscol, FS Ruggeri, FI Aigbirhio, CH Williams-G, D Klenerman Small soluble alpha-synuclein aggregates are the toxic species in Parkinson's disease Nature Communications, 2022-09-20;13(1):5512. 2022-09-20 [PMID: 36127374] (Mouse) |
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| P Boroumand, DC Prescott, T Mukherjee, PJ Bilan, M Wong, J Shen, I Tattoli, Y Zhou, A Li, T Sivasubram, N Shi, LY Zhu, Z Liu, C Robbins, DJ Philpott, SE Girardin, A Klip Bone marrow adipocytes drive the development of tissue invasive Ly6Chigh monocytes during obesity Elife, 2022-09-20;11(0):. 2022-09-20 [PMID: 36125130] (Mouse) |
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| CWS Wanderley, A Maganin, B Adjafre, AS Mendes, CE Anibal Sil, AU Quadros, JPM Luiz, CMS Silva, NR Silva, FF Oliveira, FIF Gomes, JLJ Restrepo, CA Speck-Hern, F Turaça, GVL Silva, GR Pigatto, HI Nakaya, JM Mota, R Barroso-So, JC Alves-Filh, TM Cunha, FQ Cunha PD-1/PD-L1 inhibition enhances chemotherapy-induced neuropathic pain by suppressing neuroimmune antinociceptive signaling Cancer Immunology Research, 2022-11-02;0(0):. 2022-11-02 [PMID: 36083496] (Mouse) |
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| Z Ni, H Li, D Mu, J Hou, X Liu, S Tang, S Zheng Rapamycin Alleviates 2,4,6-Trinitrobenzene Sulfonic Acid-Induced Colitis through Autophagy Induction and NF-kappaB Pathway Inhibition in Mice Mediators of Inflammation, 2022-08-18;2022(0):2923216. 2022-08-18 [PMID: 36032781] (Mouse) |
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| Y Zhang, L Zhu, J Hong, C Chen Extracellular matrix of early pulmonary fibrosis modifies the polarization of alveolar macrophage International immunopharmacology, 2022-08-24;111(0):109179. 2022-08-24 [PMID: 36029666] (Mouse) |
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| Y Ni, GH Wu, JJ Cai, R Zhang, Y Zheng, JQ Liu, XH Yang, X Yang, Y Shen, JM Lai, XM Ye, SJ Mo Tubule-mitophagic secretion of SerpinG1 reprograms macrophages to instruct anti-septic acute kidney injury efficacy of high-dose ascorbate mediated by NRF2 transactivation International journal of biological sciences, 2022-08-08;18(13):5168-5184. 2022-08-08 [PMID: 35982894] (Mouse) |
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| M Pereira, DF Durso, CE Bryant, EA Kurt-Jones, N Silverman, DT Golenbock, RT Gazzinelli The IRAK4 scaffold integrates TLR4-driven TRIF and MYD88 signaling pathways Cell Reports, 2022-08-16;40(7):111225. 2022-08-16 [PMID: 35977521] (Mouse) |
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| SJ Matissek, M Karbalivan, W Han, A Boutilier, E Yzar-Garci, LL Kehoe, DS Gardner, A Hage, K Fleck, V Jeffers, R Rajsbaum, SF Elsawa A novel mechanism of regulation of the oncogenic transcription factor GLI3 by toll-like receptor signaling Oncotarget, 2022-08-03;13(0):944-959. 2022-08-03 [PMID: 35937499] (Mouse) |
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| PHF Sucupira, TR Moura, ILS Gurgel, TTP Pereira, ACB Padovan, MM Teixeira, D Bahia, FM Soriani In vitro and in vivo Characterization of Host-Pathogen Interactions of the L3881 Candida albicans Clinical Isolate Frontiers in Microbiology, 2022-07-11;13(0):901442. 2022-07-11 [PMID: 35898912] (Mouse) |
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| CLD Amaral, ÍCA Martins, ACC Veras, FM Simabuco, MG Ross, M Desai, LM Ignácio-So, M Milanski, AS Torsoni, MA Torsoni Activation of the alpha7 Nicotinic Acetylcholine Receptor Prevents against Microglial-Induced Inflammation and Insulin Resistance in Hypothalamic Neuronal Cells Cells, 2022-07-14;11(14):. 2022-07-14 [PMID: 35883638] (Mouse) |
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| J Hu, Y Zhang, S Yi, C Wang, X Huang, S Pan, J Yang, G Yuan, S Tan, H Li Lithocholic acid inhibits dendritic cell activation by reducing intracellular glutathione via TGR5 signaling International journal of biological sciences, 2022-07-11;18(11):4545-4559. 2022-07-11 [PMID: 35864954] (Mouse) |
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| PS Woods, LM Kimmig, KA Sun, AY Meliton, OR Shamaa, Y Tian, R Cetin-Atal, WW Sharp, RB Hamanaka, GM Mutlu HIF-1alpha induces glycolytic reprograming in tissue-resident alveolar macrophages to promote cell survival during acute lung injury Elife, 2022-07-13;11(0):. 2022-07-13 [PMID: 35822617] (Mouse) |
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| H Sun, X Wan, Y Fan, P Liu, Y Song, N Zhu, Z Duan, Q Wang, F Chen, C Zhou, Y Zheng, P Ding, F Liu, L Feng, KS Kim, L Wang Bacteria reduce flagellin synthesis to evade microglia-astrocyte-driven immunity in the brain Cell Reports, 2022-07-05;40(1):111033. 2022-07-05 [PMID: 35793624] (Mouse) |
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| AL Saraiva, AB Justino, RR Franco, HCG Silva, FDS Arruda, SG Klein, MRN Celes, LR Goulart, FS Espindola Polyphenols-Rich Fraction from Annona muricata Linn. Leaves Attenuates Oxidative and Inflammatory Responses in Neutrophils, Macrophages, and Experimental Lung Injury Pharmaceutics, 2022-05-31;14(6):. 2022-05-31 [PMID: 35745755] (Mouse) |
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| S Zhao, Z Huang, H Jiang, J Xiu, L Zhang, Q Long, Y Yang, L Yu, L Lu, H Gu Sirtuin 1 Induces Choroidal Neovascularization and Triggers Age-Related Macular Degeneration by Promoting LCN2 through SOX9 Deacetylation Oncogene, 2022-06-09;2022(0):1671438. 2022-06-09 [PMID: 35720180] (Mouse) |
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| DJ Brinkman, T Simon, AS Ten Hove, K Zafeiropou, O Welting, PHP van Hamers, RA Willemze, AYFL Yim, C Verseijden, TBM Hakvoort, MD Luyer, MJ Vervoordel, P Blancou, WJ de Jonge Electrical stimulation of the splenic nerve bundle ameliorates dextran sulfate sodium-induced colitis in mice Journal of Neuroinflammation, 2022-06-17;19(1):155. 2022-06-17 [PMID: 35715845] (Mouse) |
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| A Dietschman, S Schruefer, S Westermann, F Henkel, K Castiglion, R Willebrand, J Adam, J Ruland, R Lang, DC Sheppard, J Esser-von-, D Radtke, S Krappmann, D Voehringer Phosphatidylinositol 3-Kinase (PI3K) Orchestrates Aspergillus fumigatus-Induced Eosinophil Activation Independently of Canonical Toll-Like Receptor (TLR)/C-Type-Lectin Receptor (CLR) Signaling MBio, 2022-06-13;0(0):e0123922. 2022-06-13 [PMID: 35695427] (Mouse) |
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| SY Park, H Yang, M Ye, X Liu, I Shim, YT Chang, H Bae Neuroprotective effects of ex vivo-expanded regulatory T cells on trimethyltin-induced neurodegeneration in mice Journal of Neuroinflammation, 2022-06-11;19(1):143. 2022-06-11 [PMID: 35690816] (Mouse) |
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| H Choe, BS Hausman, KM Hujer, O Akkus, PN Rather, Z Lee, RA Bonomo, EM Greenfield Acinetobacter quorum sensing contributes to inflammation-induced inhibition of orthopaedic implant osseointegration Oncogene, 2022-06-09;43(0):267-276. 2022-06-09 [PMID: 35678763] (Mouse) |
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| HI Muendlein, WM Connolly, Z Magri, D Jetton, I Smirnova, A Degterev, S Balachandr, A Poltorak ZBP1 promotes inflammatory responses downstream of TLR3/TLR4 via timely delivery of RIPK1 to TRIF Proceedings of the National Academy of Sciences of the United States of America, 2022-06-06;119(24):e2113872119. 2022-06-06 [PMID: 35666872] (Mouse) |
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| Q Yang, Z Wang, CHH Hor, H Xiao, Z Bian, JJ Wang Asymmetric synthesis of flavanols via Cu-catalyzed kinetic resolution of chromenes and their anti-inflammatory activity Science Advances, 2022-06-03;8(22):eabm9603. 2022-06-03 [PMID: 35658029] (Mouse) |
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| Y Xu, Y Xu, H Blevins, C Guo, S Biby, XY Wang, C Wang, S Zhang Development of sulfonamide-based NLRP3 inhibitors: Further modifications and optimization through structure-activity relationship studies European Journal of Medicinal Chemistry, 2022-05-21;238(0):114468. 2022-05-21 [PMID: 35635948] (Mouse) |
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| K Hayashi, K Sato, S Ochi, S Kawano, S Munesue, A Harashima, Y Oshima, K Kimura, T Kyoi, Y Yamamoto Inhibitory Effects of Saururus chinensis Extract on Receptor for Advanced Glycation End-Products-Dependent Inflammation and Diabetes-Induced Dysregulation of Vasodilation International Journal of Molecular Sciences, 2022-05-20;23(10):. 2022-05-20 [PMID: 35628567] (Mouse) |
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| Z Ferdous, S Al-Salam, P Yuvaraju, BH Ali, A Nemmar Remote effects and biodistribution of pulmonary instilled silver nanoparticles in mice NanoImpact, 2021-03-13;22(0):100310. 2021-03-13 [PMID: 35559967] (Mouse) |
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| AM Jeffries, AJ Suptela, I Marriott Z-DNA binding protein 1 mediates necroptotic and apoptotic cell death pathways in murine astrocytes following herpes simplex virus-1 infection Journal of Neuroinflammation, 2022-05-13;19(1):109. 2022-05-13 [PMID: 35549723] (Mouse) |
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| A Ulu, S Sveiven, A Bilg, JV Velazquez, M Diaz, M Mukherjee, AG Yuil-Valde, S Kota, A Burr, A Najera, TM Nordgren IL-22 regulates inflammatory responses to agricultural dust-induced airway inflammation Toxicology and Applied Pharmacology, 2022-05-05;0(0):116044. 2022-05-05 [PMID: 35525330] (Mouse) |
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| LK Billingham, JS Stoolman, K Vasan, AE Rodriguez, TA Poor, M Szibor, HT Jacobs, CR Reczek, A Rashidi, P Zhang, J Miska, NS Chandel Mitochondrial electron transport chain is necessary for NLRP3 inflammasome activation Nature Immunology, 2022-04-28;0(0):. 2022-04-28 [PMID: 35484407] (Mouse) |
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| MMS Hamoud, NA Osman, S Rezq, H A A Abd El, A E A Hassan, HA Abdel-Fatt, DG Romero, AM Ghanim Design and Synthesis of Novel 1,3,4-Oxadiazole and 1,2,4-Triazole Derivatives as Cyclooxygenase-2 Inhibitors with Anti-inflammatory and Antioxidant activity in LPS-stimulated RAW264.7 Macrophages Bioorganic chemistry, 2022-04-13;124(0):105808. 2022-04-13 [PMID: 35447409] (Mouse) |
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| A Moshensky, CS Brand, H Alhaddad, J Shin, JA Masso-Silv, I Advani, D Gunge, A Sharma, S Mehta, A Jahan, S Nilaad, J Olay, W Gu, T Simonson, D Almarghala, J Pham, S Perera, K Park, R Al-Kolla, H Moon, S Das, M Byun, Z Shah, Y Sari, J Heller Bro, LE Crotty Ale Effects of mango and mint pod-based e-cigarette aerosol inhalation on inflammatory states of the brain, lung, heart, and colon in mice Elife, 2022-04-12;11(0):. 2022-04-12 [PMID: 35411847] (Mouse) |
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| YH Su, JY Lin Menthone Inhalation Alleviates Local and Systemic Allergic Inflammation in Ovalbumin-Sensitized and Challenged Asthmatic Mice International Journal of Molecular Sciences, 2022-04-04;23(7):. 2022-04-04 [PMID: 35409371] (Mouse) |
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| KC Ngamsri, A Fuhr, K Schindler, M Simelitidi, M Hagen, Y Zhang, J Gamper-Tsi, FM Konrad Sevoflurane Dampens Acute Pulmonary Inflammation via the Adenosine Receptor A2B and Heme Oxygenase-1 Cells, 2022-03-24;11(7):. 2022-03-24 [PMID: 35406657] (Mouse) |
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| JT Hinkle, J Patel, N Panicker, SS Karuppagou, D Biswas, B Belingon, R Chen, S Brahmachar, O Pletnikova, JC Troncoso, VL Dawson, TM Dawson STING mediates neurodegeneration and neuroinflammation in nigrostriatal alpha-synucleinopathy Proceedings of the National Academy of Sciences of the United States of America, 2022-04-08;119(15):e2118819119. 2022-04-08 [PMID: 35394877] (Mouse) |
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| H Wang, Y Chen, X Liu, R Zhang, X Wang, Q Zhang, Y Wei, F Fang, Y Yuan, Q Zhou, Y Dong, S Shi, X Jiang, X Li TNF-alpha derived from arsenite-induced microglia activation mediated neuronal necroptosis Ecotoxicology and environmental safety, 2022-04-01;236(0):113468. 2022-04-01 [PMID: 35378400] (Mouse) |
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| Y Hiramatsu, K Suzuki, T Nishida, N Onoda, T Satoh, S Akira, M Ikawa, H Ikeda, J Kamei, S Derouiche, M Tominaga, Y Horiguchi The Mechanism of Pertussis Cough Revealed by the Mouse-Coughing Model MBio, 2022-03-31;0(0):e0319721. 2022-03-31 [PMID: 35357202] (Mouse) |
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| GS McElroy, RP Chakrabart, KB D'Alessand, K Vasan, J Tan, JS Stoolman, SE Weinberg, EM Steinert, PA Reyfman, BD Singer, WC Ladiges, L Gao, J Lopéz-Barn, GRS Budinger, NS Chandel Reduced expression of mitochondrial complex I subunit Ndufs2 does not impact healthspan in mice Scientific Reports, 2022-03-25;12(1):5196. 2022-03-25 [PMID: 35338200] (Mouse) |
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| E Singh, RAM Osmani, R Banerjee, AS Abu Lila, A Moin, K Almansour, HH Arab, HF Alotaibi, ES Khafagy Poly epsilon-Caprolactone Nanoparticles for Sustained Intra-Articular Immune Modulation in Adjuvant-Induced Arthritis Rodent Model Pharmaceutics, 2022-02-26;14(3):. 2022-02-26 [PMID: 35335895] (Mouse) |
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| XAMH van Dieren, F Vrieling, L Smeehuijze, L Deng, JP Boogaard, CA Croes, L Temmerman, S Wetzels, E Biessen, S Kersten, R Stienstra Triglyceride breakdown from lipid droplets regulates the inflammatory response in macrophages Proceedings of the National Academy of Sciences of the United States of America, 2022-03-18;119(12):e2114739119. 2022-03-18 [PMID: 35302892] (Mouse) |
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| DG Barone, A Carnicer-L, P Tourlomous, RS Hamilton, M Prater, AL Rutz, IB Dimov, GG Malliaras, SP Lacour, AAB Robertson, K Franze, JW Fawcett, CE Bryant Prevention of the foreign body response to implantable medical devices by inflammasome inhibition Proceedings of the National Academy of Sciences of the United States of America, 2022-03-17;119(12):e2115857119. 2022-03-17 [PMID: 35298334] (Mouse) |
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| C Ajish, S Yang, SD Kumar, EY Kim, HJ Min, CW Lee, SH Shin, SY Shin A novel hybrid peptide composed of LfcinB6 and KR-12-a4 with enhanced antimicrobial, anti-inflammatory and anti-biofilm activities Scientific Reports, 2022-03-14;12(1):4365. 2022-03-14 [PMID: 35288606] (Mouse) |
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| E Sugisawa, T Kondo, Y Kumagai, H Kato, Y Takayama, K Isohashi, E Shimosegaw, N Takemura, Y Hayashi, T Sasaki, MM Martino, M Tominaga, K Maruyama Nociceptor-derived Reg3gamma prevents endotoxic death by targeting kynurenine pathway in microglia Cell Reports, 2022-03-08;38(10):110462. 2022-03-08 [PMID: 35263589] (Mouse) |
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| F Scopelliti, L Mercurio, C Cattani, V Dimartino, C Albanesi, G Costanzo, C Mirisola, S Madonna, A Cavani The phosphoinositide-3-kinase (PI3K)-delta inhibitor seletalisib impairs monocyte-derived dendritic cells maturation, APC function, and promotes their migration to CCR7 and CXCR4 ligands Journal of leukocyte biology, 2022-02-24;0(0):. 2022-02-24 [PMID: 35199885] (Mouse) |
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| MS Lin, SM Chen, KF Hua, WJ Chen, CC Hsieh, CC Lin Freshwater Clam Extract Mitigates Neuroinflammation and Amplifies Neurotrophic Activity of Glia: Insights from In Vitro Model of Neurodegenerative Pathomechanism Journal of Clinical Medicine, 2022-01-22;11(3):. 2022-01-22 [PMID: 35160004] (Mouse) |
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| S Lee, BG Seok, SJ Lee, SW Chung Inhibition of mitoNEET attenuates LPS-induced inflammation and oxidative stress Cell Death & Disease, 2022-02-08;13(2):127. 2022-02-08 [PMID: 35136051] (Mouse) |
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| C Conrad, D Yildiz, SJ Cleary, A Margraf, L Cook, U Schlomann, B Panaretou, JL Bowser, H Karmouty-Q, J Li, NK Berg, SC Martin, A Aljohmani, SF Moussavi-H, KM Wang, JJ Tian, M Magnen, C Valet, L Qiu, JP Singer, HK Eltzschig, CAPSys Stu, W Bertrams, S Herold, N Suttorp, B Schmeck, ZT Ball, A Zarbock, MR Looney, JW Bartsch ADAM8 signaling drives neutrophil migration and ARDS severity JCI Insight, 2022-02-08;7(3):. 2022-02-08 [PMID: 35132956] (Mouse) |
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| RM van Harten, JLM Tjeerdsma-, A de Greeff, MD Balhuizen, A van Dijk, EJA Veldhuizen, HP Haagsman, MR Scheenstra d-enantiomers of CATH-2 enhance the response of macrophages against Streptococcus suis serotype 2 Journal of advanced research, 2021-05-26;36(0):101-112. 2021-05-26 [PMID: 35127168] (Mouse) |
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| WY Huang, YL Lai, KH Liu, S Lin, HY Chen, CH Liang, HM Wu, KS Hsu TNFalpha-mediated necroptosis in brain endothelial cells as a potential mechanism of increased seizure susceptibility in mice following systemic inflammation Journal of Neuroinflammation, 2022-02-02;19(1):29. 2022-02-02 [PMID: 35109859] (Mouse) |
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| SM Borghi, SKD Bussulo, FA Pinho-Ribe, V Fattori, TT Carvalho, FS Rasquel-Ol, TH Zaninelli, CR Ferraz, AMB Casella, FQ Cunha, TM Cunha, R Casagrande, WA Verri Intense Acute Swimming Induces Delayed-Onset Muscle Soreness Dependent on Spinal Cord Neuroinflammation Frontiers in Pharmacology, 2022-01-07;12(0):734091. 2022-01-07 [PMID: 35069187] (Mouse) |
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| PATS Castro, GM Barbosa, DH Machanocke, RS Peres, TM Cunha, JE Cunha, FFB Oliveira, FS Ramalho, TL Russo, FQ Cunha, TF Salvini Clinical-like cryotherapy in acute knee arthritis of the knee improves inflammation signs, pain, joint swelling, and motor performance in mice PLoS ONE, 2022-01-21;17(1):e0261667. 2022-01-21 [PMID: 35061737] (Mouse) |
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| PR da Silva, RF do Espírit, CO Melo, FE Pachú Cava, TB Costa, YV Barbosa, YMSM E Silva, NF de Sousa, CF Villarreal, RO de Moura, VL Dos Santos The Compound (E)-2-Cyano-N,3-diphenylacrylamide (JMPR-01): A Potential Drug for Treatment of Inflammatory Diseases Pharmaceutics, 2022-01-13;14(1):. 2022-01-13 [PMID: 35057082] (Mouse) |
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| R Pohl, S Feder, EM Haberl, L Rein-Fisch, TS Weiss, M Spirk, A Bruckmann, N McMullen, CJ Sinal, C Buechler Chemerin Overexpression in the Liver Protects against Inflammation in Experimental Non-Alcoholic Steatohepatitis Biomedicines, 2022-01-07;10(1):. 2022-01-07 [PMID: 35052810] (Mouse) |
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| A Nemmar, S Beegam, NE Zaaba, S Alblooshi, S Alseiari, BH Ali The Salutary Effects of Catalpol on Diesel Exhaust Particles-Induced Thrombogenic Changes and Cardiac Oxidative Stress, Inflammation and Apoptosis Biomedicines, 2022-01-04;10(1):. 2022-01-04 [PMID: 35052780] (Mouse) |
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| HI Warheit-Ni, SJ Edwards, S SenGupta, CA Parent, X Zhou, DN O'Dwyer, BB Moore Fibrotic lung disease inhibits innate immune responses to Staphylococcal pneumonia via impaired neutrophil and macrophage function JCI Insight, 2022-02-22;0(0):. 2022-02-22 [PMID: 34990413] (Mouse) |
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| HL Wang, FQ Chen, LJ Wu Ephedrine ameliorates chronic obstructive pulmonary disease (COPD) through restraining endoplasmic reticulum (ER) stress in vitro and in vivo International immunopharmacology, 2021-12-22;103(0):107842. 2021-12-22 [PMID: 34953449] (Mouse) |
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| KC Ngamsri, RA Putri, C Jans, K Schindler, A Fuhr, Y Zhang, J Gamper-Tsi, S Ehnert, FM Konrad CXCR4 and CXCR7 Inhibition Ameliorates the Formation of Platelet-Neutrophil Complexes and Neutrophil Extracellular Traps through Adora2b Signaling International Journal of Molecular Sciences, 2021-12-17;22(24):. 2021-12-17 [PMID: 34948374] (Mouse) |
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| L Huang, W Liang, K Zhou, RA Wassel, ZD Ridge, JX Ma, B Wang Therapeutic Effects of Fenofibrate Nano-Emulsion Eye Drops on Retinal Vascular Leakage and Neovascularization Biology, 2021-12-15;10(12):. 2021-12-15 [PMID: 34943243] (Mouse) |
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| J Tomala, P Weberova, B Tomalova, Z Jiraskova, L Sivak, J Kovarova, M Kovar IL-2/JES6-1 mAb complexes dramatically increase sensitivity to LPS through IFN-gamma production by CD25+Foxp3- T cells Elife, 2021-12-21;10(0):. 2021-12-21 [PMID: 34932467] (Mouse) |
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| NC Williams, DG Ryan, ASH Costa, EL Mills, MP Jedrychows, SM Cloonan, C Frezza, LA O'Neill Signalling metabolite L-2-hydroxyglutarate activates the transcription factor HIF-1alpha in lipopolysaccharide-activated macrophages The Journal of Biological Chemistry, 2021-12-17;0(0):101501. 2021-12-17 [PMID: 34929172] (Mouse) |
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| BY Lee, EKJ Hogg, CR Below, A Kononov, A Blanco-Gom, F Heider, J Xu, C Hutton, X Zhang, T Scheidt, K Beattie, A Lamarca, M McNamara, JW Valle, C Jørgensen Heterocellular OSM-OSMR signalling reprograms fibroblasts to promote pancreatic cancer growth and metastasis Nature Communications, 2021-12-17;12(1):7336. 2021-12-17 [PMID: 34921158] (Mouse) |
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| L Chen, J Deng, A Yu, Y Hu, B Jin, P Du, J Zhou, L Lei, Y Wang, S Vakal, X Li Drug-peptide supramolecular hydrogel boosting transcorneal permeability and pharmacological activity via ligand-receptor interaction Bioactive materials, 2021-09-10;10(0):420-429. 2021-09-10 [PMID: 34901557] (Mouse) |
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| M Estrázulas, RDS Freitas, ET Käfer, APA Dagnino, MM Campos Central and peripheral effects of environmental enrichment in a mouse model of arthritis International immunopharmacology, 2021-11-22;0(0):108386. 2021-11-22 [PMID: 34824037] (Mouse) |
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| KKL Wu, K Long, H Lin, PMF Siu, RLC Hoo, D Ye, A Xu, KKY Cheng The APPL1-Rab5 axis restricts NLRP3 inflammasome activation through early endosomal-dependent mitophagy in macrophages Nature Communications, 2021-11-17;12(1):6637. 2021-11-17 [PMID: 34789781] (Mouse) |
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| J Lücht, N Rolfs, SJ Wowro, F Berger, KRL Schmitt, G Tong Cooling and Sterile Inflammation in an Oxygen-Glucose-Deprivation/Reperfusion Injury Model in BV-2 Microglia Mediators of Inflammation, 2021-11-05;2021(0):8906561. 2021-11-05 [PMID: 34776788] (Mouse) |
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| HM Evans, DF Schultz, AJ Boiman, MC McKell, JE Qualls, GS Deepe Restraint of Fumarate Accrual by HIF-1alpha Preserves miR-27a-Mediated Limitation of Interleukin 10 during Infection of Macrophages by Histoplasma capsulatum MBio, 2021-11-09;0(0):e0271021. 2021-11-09 [PMID: 34749531] (Mouse) |
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| MC Kiritsy, K McCann, D Mott, SM Holland, SM Behar, CM Sassetti, AJ Olive Mitochondrial respiration contributes to the interferon gamma response in antigen-presenting cells Elife, 2021-11-02;10(0):. 2021-11-02 [PMID: 34726598] (Mouse) |
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| LAD Queiroz, JB Assis, JPT Guimarães, ESA Sousa, AC Milhomem, KKS Sunahara, A Sá-Nunes, JO Martins Endangered Lymphocytes: The Effects of Alloxan and Streptozotocin on Immune Cells in Type 1 Induced Diabetes Mediators of Inflammation, 2021-10-19;2021(0):9940009. 2021-10-19 [PMID: 34712101] (Mouse) |
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| YK Wu, ZN Ren, SL Zhu, YZ Wu, G Wang, H Zhang, W Chen, Z He, XL Ye, QX Zhai Sulforaphane ameliorates non-alcoholic fatty liver disease in mice by promoting FGF21/FGFR1 signaling pathway Acta pharmacologica Sinica, 2021-10-15;0(0):. 2021-10-15 [PMID: 34654875] (Mouse) |
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| JR Santin, L Benvenutti, MF Broering, R Nunes, FC Goldoni, YBK Patel, JA de Souza, MAT Kopp, P de Souza, RCV da Silva, MVD Pastor, AB de Souza, LD Testoni, AG Couto, TMB Bresolin, NLM Quintão Sambucus nigra: A traditional medicine effective in reducing inflammation in mice Journal of ethnopharmacology, 2021-10-11;283(0):114736. 2021-10-11 [PMID: 34648899] (Mouse) |
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| N Majumder, M Velayutham, D Bitounis, VK Kodali, MH Hasan Mazu, J Amedro, VV Khramtsov, A Erdely, T Nurkiewicz, P Demokritou, EE Kelley, S Hussain Oxidized carbon black nanoparticles induce endothelial damage through C-X-C chemokine receptor 3-mediated pathway Redox Biology, 2021-10-04;47(0):102161. 2021-10-04 [PMID: 34624601] (Mouse) |
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| AV Ferreira, RF Uijen, O Bulut, MI de Jonge, J Domínguez-, MG Netea Limited role of the spleen in a mouse model of trained immunity: Impact on neutrophilia Journal of leukocyte biology, 2021-10-01;0(0):. 2021-10-01 [PMID: 34596266] (Mouse) |
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| JR Dayton, Y Yuan, LP Pacumio, BG Dorflinger, SC Yoo, MJ Olson, SI Hernández-, MM McMahon, L Cruz-Oreng Expression of IL-20 Receptor Subunit beta Is Linked to EAE Neuropathology and CNS Neuroinflammation Frontiers in Cellular Neuroscience, 2021-09-07;15(0):683687. 2021-09-07 [PMID: 34557075] (Mouse) |
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| J Hu, C Wang, X Huang, S Yi, S Pan, Y Zhang, G Yuan, Q Cao, X Ye, H Li Gut microbiota-mediated secondary bile acids regulate dendritic cells to attenuate autoimmune uveitis through TGR5 signaling Cell Reports, 2021-09-21;36(12):109726. 2021-09-21 [PMID: 34551302] (Mouse) |
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Mouse |
| WJ Melvin, CO Audu, FM Davis, SB Sharma, A Joshi, A DenDekker, S Wolf, E Barrett, K Mangum, X Zhou, M Bame, A Ruan, A Obi, SL Kunkel, BB Moore, KA Gallagher Coronavirus induces diabetic macrophage-mediated inflammation via SETDB2 Proceedings of the National Academy of Sciences of the United States of America, 2021-09-21;118(38):. 2021-09-21 [PMID: 34479991] (Mouse) |
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Mouse |
| E Zajta, K Csonka, A Tóth, L Tiszlavicz, T Németh, A Orosz, Á Novák, M Csikós, C Vágvölgyi, A Mócsai, A Gácser Signaling through Syk or CARD9 Mediates Species-Specific Anti-Candida Protection in Bone Marrow Chimeric Mice MBio, 2021-08-31;12(4):e0160821. 2021-08-31 [PMID: 34465030] (Mouse, Transgenic Mouse) |
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Mouse, Transgenic Mouse |
| W Wang, M Kong, Y Dou, S Xue, Y Liu, Y Zhang, W Chen, Y Li, X Dai, J Meng, J Wang Selective Expression of a SNARE-Cleaving Protease in Peripheral Sensory Neurons Attenuates Pain-Related Gene Transcription and Neuropeptide Release International Journal of Molecular Sciences, 2021-08-17;22(16):. 2021-08-17 [PMID: 34445536] (Mouse) |
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Mouse |
| SKH Chow, C Cui, KYK Cheng, YN Chim, J Wang, CHW Wong, KW Ng, RMY Wong, WH Cheung Acute Inflammatory Response in Osteoporotic Fracture Healing Augmented with Mechanical Stimulation is Regulated In Vivo through the p38-MAPK Pathway International Journal of Molecular Sciences, 2021-08-13;22(16):. 2021-08-13 [PMID: 34445423] (Mouse) |
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Mouse |
| AS Wagner, TJ Hancock, SW Lumsdaine, SJ Kauffman, MM Mangrum, EK Phillips, TE Sparer, TB Reynolds Activation of Cph1 causes �(1,3)-glucan unmasking in Candida albicans and attenuates virulence in mice in a neutrophil-dependent manner PloS Pathogens, 2021-08-25;17(8):e1009839. 2021-08-25 [PMID: 34432857] (Mouse) |
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Mouse |
| N Majumder, WT Goldsmith, VK Kodali, M Velayutham, SA Friend, VV Khramtsov, TR Nurkiewicz, A Erdely, PC Zeidler-Er, V Castranova, JR Harkema, EE Kelley, S Hussain Oxidant-induced epithelial alarmin pathway mediates lung inflammation and functional decline following ultrafine carbon and ozone inhalation co-exposure Redox Biology, 2021-08-05;46(0):102092. 2021-08-05 [PMID: 34418598] (Mouse) |
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Mouse |
| L Gu, R Surolia, JL Larson-Cas, C He, D Davis, J Kang, VB Antony, AB Carter Targeting Cpt1a-Bcl-2 interaction modulates apoptosis resistance and fibrotic remodeling Cell Death and Differentiation, 2021-08-20;0(0):. 2021-08-20 [PMID: 34413485] (Mouse) |
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Mouse |
| SG Lee, DG Lee, YH Joo, N Chung Synergistic inhibitory effects of the oxyresveratrol and dacarbazine combination against melanoma cells Oncology Letters, 2021-07-14;22(3):667. 2021-07-14 [PMID: 34386089] (Mouse) |
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Mouse |
| H Ahn, G Lee, J Kim, J Park, SG Kang, SI Yoon, E Lee, GS Lee NLRP3 Triggers Attenuate Lipocalin-2 Expression Independent with Inflammasome Activation Cells, 2021-07-02;10(7):. 2021-07-02 [PMID: 34359830] (Mouse) |
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Mouse |
| L Ma, KK Dewan, DL Taylor-Mul, SM Wagner, B Linz, I Rivera, Y Su, AD Caulfield, U Blas-Macha, ET Harvill Pertactin contributes to shedding and transmission of Bordetella bronchiseptica PloS Pathogens, 2021-08-04;17(8):e1009735. 2021-08-04 [PMID: 34347835] (Mouse) |
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Mouse |
| F Almutairi, SL Tucker, D Sarr, B Rada PI3K/ NF-kappaB-dependent TNF-alpha and HDAC activities facilitate LPS-induced RGS10 suppression in pulmonary macrophages Cellular Signalling, 2021-07-31;86(0):110099. 2021-07-31 [PMID: 34339853] (Mouse) |
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Mouse |
| L Benvenutti, R Nunes, I Venturi, SA Ramos, MF Broering, FC Goldoni, SE Pavan, MVD Pastor, A Malheiros, NLM Quintão, ES Fernandes, JR Santin Anti-Inflammatory and Healing Activity of the Hydroalcoholic Fruit Extract of Solanum diploconos (Mart.) Bohs Journal of Immunology Research, 2021-07-19;2021(0):9957451. 2021-07-19 [PMID: 34337087] (Mouse) |
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Mouse |
| AM Porras, Q Shi, H Zhou, R Callahan, G Montenegro, N Solomons, IL Brito Geographic differences in gut microbiota composition impact susceptibility to enteric infection Cell Reports, 2021-07-27;36(4):109457. 2021-07-27 [PMID: 34320343] (Mouse) |
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Mouse |
| LS Rocha, BPD Silva, TML Correia, RPD Silva, DA Meireles, R Pereira, LES Netto, FC Meotti, RF Queiroz Peroxiredoxin AhpC1 protects Pseudomonas aeruginosa against the inflammatory oxidative burst and confers virulence Redox Biology, 2021-07-19;46(0):102075. 2021-07-19 [PMID: 34315109] (Mouse) |
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Mouse |
| P Reniewicz, A Kula, E Makuch, M Ochnik, T Lipi?ski, J Siednienko Ligase Pellino3 Regulates Macrophage Action and Survival in Response to VSV Infection in RIG-I-Dependent Path Oxidative Medicine and Cellular Longevity, 2021-07-01;2021(0):6668463. 2021-07-01 [PMID: 34306313] (Mouse) |
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Mouse |
| A Hickey, P Stamou, S Udayan, A Ramón-Vázq, M Esteban-To, F Bottacini, JA Woznicki, O Hughes, S Melgar, M Ventura, D Van Sinder, V Rossini, K Nally Bifidobacterium breve Exopolysaccharide Blocks Dendritic Cell Maturation and Activation of CD4+ T Cells Frontiers in Microbiology, 2021-06-16;12(0):653587. 2021-06-16 [PMID: 34220742] (Mouse) |
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Mouse |
| CC Lin, YR Shen, CC Chang, XY Guo, YY Young, TY Lai, IS Yu, CY Lee, TH Chuang, HY Tsai, LC Hsu Terminal uridyltransferase 7 regulates TLR4-triggered inflammation by controlling Regnase-1 mRNA uridylation and degradation Nature Communications, 2021-06-29;12(1):3878. 2021-06-29 [PMID: 34188032] (Mouse) |
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Mouse |
| DJ Levy, A Goundry, RSS Laires, TFR Costa, CM Novo, DJ Grab, JC Mottram, APCA Lima Role of the inhibitor of serine peptidase 2 (ISP2) of Trypanosoma brucei rhodesiense in parasite virulence and modulation of the inflammatory responses of the host PloS Neglected Tropical Diseases, 2021-06-21;15(6):e0009526. 2021-06-21 [PMID: 34153047] (Mouse) |
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Mouse |
| A Doni, R Parente, I Laface, E Magrini, C Cunha, FS Colombo, JF Lacerda, A Campos, SN Mapelli, F Petroni, R Porte, T Schorn, A Inforzato, T Mercier, K Lagrou, J Maertens, JD Lambris, B Bottazzi, C Garlanda, M Botto, A Carvalho, A Mantovani Serum amyloid P component is an essential element of resistance against Aspergillus fumigatus Nature Communications, 2021-06-18;12(1):3739. 2021-06-18 [PMID: 34145258] (Mouse) |
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Mouse |
| A Ulu, A Burr, AJ Heires, J Pavlik, T Larsen, PA Perez, C Bravo, NV DiPatrizio, M Baack, DJ Romberger, TM Nordgren A high docosahexaenoic acid diet alters lung inflammation and recovery following repetitive exposure to aqueous organic dust extracts: Role of DHA in repetitive organic dust exposure The Journal of nutritional biochemistry, 2021-06-12;0(0):108797. 2021-06-12 [PMID: 34126202] (Mouse) |
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Mouse |
| N Lee, YJ Heo, SE Choi, JY Jeon, SJ Han, DJ Kim, Y Kang, KW Lee, HJ Kim Anti-inflammatory Effects of Empagliflozin and Gemigliptin on LPS-Stimulated Macrophage via the IKK/NF-&kappaB, MKK7/JNK, and JAK2/STAT1 Signalling Pathways Journal of Immunology Research, 2021-06-02;2021(0):9944880. 2021-06-02 [PMID: 34124273] (Mouse) |
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Mouse |
| PJ Chiu, J Rathod, YP Hong, PJ Tsai, YP Hung, WC Ko, JW Chen, D Paredes-Sa, IH Huang Clostridioides difficile spores stimulate inflammatory cytokine responses and induce cytotoxicity in macrophages Anaerobe, 2021-05-31;70(0):102381. 2021-05-31 [PMID: 34082120] (Mouse) |
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Mouse |
| P Diez-Echav, I Martín-Cab, J Garrido-Me, S Langa, T Vezza, JM Landete, L Hidalgo-Ga, F Algieri, MJ Mayer, A Narbad, A García-Laf, M Medina, A Rodríguez-, ME Rodríguez-, J Gálvez, JL Arqués Probiotic and Functional Properties of Limosilactobacillus reuteri INIA P572 Nutrients, 2021-05-29;13(6):. 2021-05-29 [PMID: 34072532] (Mouse) |
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Mouse |
| SE Huang, E Sulistyowa, YY Chao, BN Wu, ZK Dai, JH Hsu, JL Yeh In Vitro Evaluation of the Anti-Inflammatory Effect of KMUP-1 and In Vivo Analysis of Its Therapeutic Potential in Osteoarthritis Biomedicines, 2021-05-28;9(6):. 2021-05-28 [PMID: 34071594] (Mouse) |
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Mouse |
| V Farré-Alin, A Palomino-A, P Narros-Fer, AB Lopez-Rodr, C Decouty-Pe, A Muñoz-Mont, J Zamorano-F, B Mansilla-F, J Giner-Garc, P García-Fei, M Sáez-Alegr, AJ Palpán-Flo, JM Roda-Frade, CS Carabias, JM Rosa, B Civantos-M, S Yus-Teruel, L Gandía, A Lagares, BJ Hernández-, J Egea Serum Amyloid A1/Toll-Like Receptor-4 Axis, an Important Link between Inflammation and Outcome of TBI Patients Biomedicines, 2021-05-25;9(6):. 2021-05-25 [PMID: 34070533] (Mouse) |
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Mouse |
| MTP de Oliveir, DS Coutinho, SS Guterres, AR Pohlmann, PMRE Silva, MA Martins, A Bernardi Resveratrol-Loaded Lipid-Core Nanocapsules Modulate Acute Lung Inflammation and Oxidative Imbalance Induced by LPS in Mice Pharmaceutics, 2021-05-10;13(5):. 2021-05-10 [PMID: 34068619] (Mouse) |
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Mouse |
| L Liu, Y Wu, B Wang, Y Jiang, L Lin, X Li, S Yang DA-DRD5 signaling controls colitis by regulating colonic M1/M2 macrophage polarization Cell Death & Disease, 2021-05-17;12(6):500. 2021-05-17 [PMID: 34001860] (Mouse) |
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Mouse |
| J Wu, N Chen, Y Liu, G Godlewski, HJ Kaplan, SH Shrader, ZH Song, H Shao Studies of involvement of G-protein coupled receptor-3 in cannabidiol effects on inflammatory responses of mouse primary astrocytes and microglia PLoS ONE, 2021-05-13;16(5):e0251677. 2021-05-13 [PMID: 33984046] (Mouse) |
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Mouse |
| MN Rana, J Lu, E Xue, J Ruan, Y Liu, L Zhang, R Dhar, Y Li, Z Hu, J Zhou, W Ma, H Tang PDE9 Inhibitor PF-04447943 Attenuates DSS-Induced Colitis by Suppressing Oxidative Stress, Inflammation, and Regulating T-Cell Polarization Frontiers in Pharmacology, 2021-04-08;12(0):643215. 2021-04-08 [PMID: 33967779] (Mouse) |
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Mouse |
| F Virga, F Cappelless, B Stijlemans, AT Henze, R Trotta, J Van Audena, AS Mirchandan, MA Sanchez-Ga, J Vandewalle, F Orso, C Riera-Domi, A Griffa, C Ivan, E Smits, D Laoui, F Martelli, L Langouche, G Van den Be, O Feron, B Ghesquière, H Prenen, C Libert, SR Walmsley, C Corbet, JA Van Ginder, M Ivan, D Taverna, M Mazzone Macrophage miR-210 induction and metabolic reprogramming in response to pathogen interaction boost life-threatening inflammation Science Advances, 2021-05-07;7(19):. 2021-05-07 [PMID: 33962944] (Mouse) |
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Mouse |
| J Lora, G Weskamp, TM Li, T Maretzky, DTN Shola, S Monette, SF Lichtentha, TT Lu, C Yang, CP Blobel Targeted truncation of the ADAM17 cytoplasmic domain in mice results in protein destabilization and a hypomorphic phenotype The Journal of Biological Chemistry, 2021-05-04;0(0):100733. 2021-05-04 [PMID: 33957124] (Mouse) |
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Mouse |
| B Friedrich, JP Auger, S Dutz, I Cicha, E Schreiber, J Band, AR Boccacccin, G Krönke, C Alexiou, R Tietze Hydroxyapatite-Coated SPIONs and Their Influence on Cytokine Release International Journal of Molecular Sciences, 2021-04-16;22(8):. 2021-04-16 [PMID: 33923700] (Mouse) |
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Mouse |
| B Venkataram, S Almarzooqi, V Raj, AT Alhassani, AS Alhassani, KJ Ahmed, VS Subramania, SK Ojha, S Attoub, TE Adrian, SB Subramanya Thymoquinone, a Dietary Bioactive Compound, Exerts Anti-Inflammatory Effects in Colitis by Stimulating Expression of the Colonic Epithelial PPAR-&gamma Transcription Factor Nutrients, 2021-04-17;13(4):. 2021-04-17 [PMID: 33920708] (Mouse) |
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Mouse |
| JP Martins, LC Silva, MS Nunes, G Rübensam, JR Oliveira, RBM Silva, MM Campos Combined Effects of Exercise and Phytoanabolic Extracts in Castrated Male and Female Mice Nutrients, 2021-04-02;13(4):. 2021-04-02 [PMID: 33918334] (Mouse) |
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Mouse |
| CF Ellefsen, CW Wold, AL Wilkins, F Rise, ABC Samuelsen Water-soluble polysaccharides from Pleurotus eryngii fruiting bodies, their activity and affinity for Toll-like receptor 2 and dectin-1 Carbohydrate polymers, 2021-03-26;264(0):117991. 2021-03-26 [PMID: 33910729] (Mouse) |
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Mouse |
| AM Ghanim, S Rezq, TS Ibrahim, DG Romero, H Kothayer Novel 1,2,4-triazine-quinoline hybrids: The privileged scaffolds as potent multi-target inhibitors of LPS-induced inflammatory response via dual COX-2 and 15-LOX inhibition European Journal of Medicinal Chemistry, 2021-04-20;219(0):113457. 2021-04-20 [PMID: 33892270] (Mouse) |
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Mouse |
| H Shokirova, T Inomata, T Saitoh, J Zhu, K Fujio, Y Okumura, A Yanagawa, K Fujimoto, J Sung, A Eguchi, M Miura, K Nagino, K Hirosawa, M Kuwahara, Y Akasaki, H Nagase, A Murakami Topical administration of the kappa opioid receptor agonist nalfurafine suppresses corneal neovascularization and inflammation Scientific Reports, 2021-04-21;11(1):8647. 2021-04-21 [PMID: 33883646] (Mouse) |
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Mouse |
| S Eto, H Yanai, S Hangai, D Kato, R Nishimura, T Nakagawa The impact of damage-associated molecules released from canine tumor cells on gene expression in macrophages Scientific Reports, 2021-04-19;11(1):8525. 2021-04-19 [PMID: 33875721] (Canine) |
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Canine |
| LA Rojas-Coló, PK Dash, FA Morales-Ví, M Lebrón-Dáv, PA Ferchmin, JB Redell, G Maldonado-, WI Vélez-Torr 4R-cembranoid confers neuroprotection against LPS-induced hippocampal inflammation in mice Journal of Neuroinflammation, 2021-04-19;18(1):95. 2021-04-19 [PMID: 33874954] (Mouse) |
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Mouse |
| R Peruzzo, S Corrà, R Costa, M Brischigli, T Varanita, L Biasutto, C Rampazzo, D Ghezzi, L Leanza, M Zoratti, M Zeviani, C De Pittà, C Viscomi, R Costa, I Szabò Exploiting pyocyanin to treat mitochondrial disease due to respiratory complex III dysfunction Nature Communications, 2021-04-08;12(1):2103. 2021-04-08 [PMID: 33833234] (Mouse) |
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Mouse |
| G Cavalli, IW Tengesdal, M Gresnigt, T Nemkov, RJW Arts, J Domínguez-, R Molteni, D Stefanoni, E Cantoni, L Cassina, S Giugliano, K Schraa, TS Mills, EM Pietras, EZ Eisenmenss, L Dagna, A Boletta, A D'Alessand, LAB Joosten, MG Netea, CA Dinarello The anti-inflammatory cytokine interleukin-37 is an inhibitor of trained immunity Cell Reports, 2021-04-06;35(1):108955. 2021-04-06 [PMID: 33826894] (Mouse) |
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Mouse |
| M Najibi, HH Honwad, JA Moreau, SM Becker, JE Irazoqui A NOVEL NOX/PHOX-CD38-NAADP-TFEB AXIS IMPORTANT FOR MACROPHAGE ACTIVATION DURING BACTERIAL PHAGOCYTOSIS Autophagy, 2021-04-13;0(0):. 2021-04-13 [PMID: 33818279] (Mouse) |
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Mouse |
| D Arsenijevi, B Stojanovic, J Milovanovi, A Arsenijevi, M Simic, M Pergal, I Kodranov, O Cvetkovic, D Vojvodic, E Ristanovic, D Manojlovic, M Milovanovi, N Arsenijevi Hepatoprotective Effect of Mixture of Dipropyl Polysulfides in Concanavalin A-Induced Hepatitis Nutrients, 2021-03-22;13(3):. 2021-03-22 [PMID: 33809904] (Mouse) |
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Mouse |
| M Sebastian-, H Wu, M Al Rahim, R Sanchez, K Kumar, RJ De Vita, GM Pasinetti Discovery and characterization of small molecule inhibitors of NLRP3 and NLRC4 inflammasomes The Journal of Biological Chemistry, 2021-03-26;0(0):100597. 2021-03-26 [PMID: 33781745] (Mouse) |
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Mouse |
| EF Lim, V Hoghooghi, KM Hagen, K Kapoor, A Frederick, TM Finlay, SS Ousman Presence and activation of pro-inflammatory macrophages are associated with CRYAB expression in vitro and after peripheral nerve injury Journal of Neuroinflammation, 2021-03-24;18(1):82. 2021-03-24 [PMID: 33761953] (Mouse) |
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Mouse |
| C Loira-Past, K Vanvarenbe, B Ucakar, M Machado Fr, A Staub, M Lemaire, JC Renauld, R Vanbever Encapsulation of a CpG oligonucleotide in cationic liposomes enhances its local antitumor activity following pulmonary delivery in a murine model of metastatic lung cancer International journal of pharmaceutics, 2021-03-19;600(0):120504. 2021-03-19 [PMID: 33753161] (Mouse) |
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Mouse |
| FR Pinheiro-N, EM Lopes, BT Acha, LDS Gomes, WA Dias, ACD Reis Filho, BS Leal, DCDN Rodrigues, JDN Silva, D Dittz, PMP Ferreira, FRC Almeida &alpha-Phellandrene exhibits antinociceptive and tumor-reducing effects in a mouse model of oncologic pain Toxicology and Applied Pharmacology, 2021-03-17;418(0):115497. 2021-03-17 [PMID: 33744277] (Mouse) |
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Mouse |
| CK Lin, TH Huang, CT Yang, CS Shi Roles of lung-recruited monocytes and pulmonary Vascular Endothelial Growth Factor (VEGF) in resolving Ventilator-Induced Lung Injury (VILI) PLoS ONE, 2021-03-19;16(3):e0248959. 2021-03-19 [PMID: 33740009] (Mouse) |
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Mouse |
| K Phulphagar, LI Kühn, S Ebner, A Frauenstei, JJ Swietlik, J Rieckmann, F Meissner Proteomics reveals distinct mechanisms regulating the release of cytokines and alarmins during pyroptosis Cell Reports, 2021-03-09;34(10):108826. 2021-03-09 [PMID: 33691121] (Mouse) |
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Mouse |
| M Bambouskov, L Potuckova, T Paulenda, M Kerndl, DA Mogilenko, K Lizotte, A Swain, S Hayes, RD Sheldon, H Kim, U Kapadnis, AE Ellis, C Isaguirre, S Burdess, A Laha, GK Amarasingh, V Chubukov, TP Roddy, MS Diamond, RG Jones, DM Simons, MN Artyomov Itaconate confers tolerance to late NLRP3 inflammasome activation Cell Reports, 2021-03-09;34(10):108756. 2021-03-09 [PMID: 33691097] (Mouse) |
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Mouse |
| JK Dowling, R Afzal, LJ Gearing, MP Cervantes-, S Annett, GM Davis, C De Santi, N Assmann, K Dettmer, DJ Gough, GR Bantug, FI Hamid, FK Nally, CP Duffy, AL Gorman, AM Liddicoat, EC Lavelle, C Hess, PJ Oefner, DK Finlay, GP Davey, T Robson, AM Curtis, PJ Hertzog, BRG Williams, CE McCoy Mitochondrial arginase-2 is essential for IL-10 metabolic reprogramming of inflammatory macrophages Nature Communications, 2021-03-05;12(1):1460. 2021-03-05 [PMID: 33674584] (Mouse) |
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Mouse |
| RDC da Cunha d, JJ Simão, VSD Silva, TM Farias, MM Cruz, VJ Antraco, L Armelin-Co, MI Alonso-Val Fish Oil Enriched in EPA, but Not in DHA, Reverses the Metabolic Syndrome and Adipocyte Dysfunction Induced by a High-Fat Diet Nutrients, 2021-02-26;13(3):. 2021-02-26 [PMID: 33652751] (Mouse) |
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Mouse |
| JM Hong, JE Kim, SK Min, KH Kim, SJ Han, JH Yim, H Park, JH Kim, IC Kim Anti-Inflammatory Effects of Antarctic Lichen Umbilicaria antarctica Methanol Extract in Lipopolysaccharide-Stimulated RAW 264.7 Macrophage Cells and Zebrafish Model BioMed Research International, 2021-02-16;2021(0):8812090. 2021-02-16 [PMID: 33644231] (Mouse) |
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Mouse |
| X Xiao, D Liu, S Chen, X Li, M Ge, W Huang Sevoflurane preconditioning activates HGF/Met-mediated autophagy to attenuate hepatic ischemia-reperfusion injury in mice Cellular Signalling, 2021-02-25;0(0):109966. 2021-02-25 [PMID: 33639217] (Mouse) |
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Mouse |
| Y Mishima, T Osaki, A Shimada, S Kamiya, S Hasegawa-I Sex-dependent differences in the gut microbiota following chronic nasal inflammation in adult mice Scientific Reports, 2021-02-25;11(1):4640. 2021-02-25 [PMID: 33633180] (Mouse) |
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Mouse |
| MG Granja, LP Alves, M Leardini-T, ME Saul, LC Bortoni, FM de Moraes, EC Ferreira, BPT de Moraes, VZ da Silva, AFR Dos Santos, AR Silva, CF Gonçalves-, V Bambini-Ju, AS Weyrich, MT Rondina, GA Zimmerman, HC de Castro- Inflammatory, synaptic, motor, and behavioral alterations induced by gestational sepsis on the offspring at different stages of life Journal of Neuroinflammation, 2021-02-25;18(1):60. 2021-02-25 [PMID: 33632243] (Mouse) |
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Mouse |
| M Kalisz, M Chmielowsk, L Marty?ska, A Doma?ska, W Bik, A Litwiniuk All-trans-retinoic acid ameliorates atherosclerosis, promotes perivascular adipose tissue browning, and increases adiponectin production in Apo-E mice Scientific Reports, 2021-02-24;11(1):4451. 2021-02-24 [PMID: 33627760] (Mouse) |
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Mouse |
| CM Restrepo, A Llanes, L Herrera, E Ellis, R Lleonart, PL Fernández Gene expression patterns associated with Leishmania panamensis infection in macrophages from BALB/c and C57BL/6 mice PloS Neglected Tropical Diseases, 2021-02-22;15(2):e0009225. 2021-02-22 [PMID: 33617537] (Mouse) |
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Mouse |
| B Dunkhuntho, C Talabnin, M Murphy, K Thumanu, P Sittisart, G Eumkeb Gymnema inodorum (Lour.) Decne. Extract Alleviates Oxidative Stress and Inflammatory Mediators Produced by RAW264.7 Macrophages Oxidative Medicine and Cellular Longevity, 2021-02-04;2021(0):8658314. 2021-02-04 [PMID: 33613825] (Mouse) |
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Mouse |
| DJ Su, LF Li, SY Wang, Q Yang, YJ Wu, MG Zhao, L Yang Pra-C exerts analgesic effect through inhibiting microglial activation in anterior cingulate cortex in complete Freund's adjuvant-induced mouse model Molecular pain, 2021-01-01;17(0):1744806921990. 2021-01-01 [PMID: 33590786] (Mouse) |
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Mouse |
| A Amend, N Wickli, AL Schäfer, DTL Sprenger, RA Manz, RE Voll, N Chevalier Dual Role of Interleukin-10 in Murine NZB/W F1 Lupus International Journal of Molecular Sciences, 2021-01-29;22(3):. 2021-01-29 [PMID: 33572870] (Mouse) |
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Mouse |
| M Garg, S Johri, S Sagar, A Mundhada, A Agrawal, P Ray, K Chakrabort Cardiolipin-mediated PPAR&gamma S112 phosphorylation impairs IL-10 production and inflammation resolution during bacterial pneumonia Cell Reports, 2021-02-09;34(6):108736. 2021-02-09 [PMID: 33567272] (Mouse) |
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Mouse |
| JS Ha, HR Choi, IS Kim, EA Kim, SW Cho, SJ Yang Hypoxia-Induced S100A8 Expression Activates Microglial Inflammation and Promotes Neuronal Apoptosis International Journal of Molecular Sciences, 2021-01-26;22(3):. 2021-01-26 [PMID: 33530496] (Mouse) |
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Mouse |
| S Estfanous, K Krause, MNK Anne, M Eltobgy, K Caution, A Abu Khweek, K Hamilton, A Badr, K Daily, C Carafice, D Baetzhold, X Zhang, T Li, H Wen, MA Gavrilin, H Haffez, S Soror, AO Amer Gasdermin D restricts Burkholderia cenocepacia infection in vitro and in vivo Scientific Reports, 2021-01-13;11(1):855. 2021-01-13 [PMID: 33441602] (Mouse) |
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Mouse |
| S Covarrubia, AC Vollmers, A Capili, M Boettcher, A Shulkin, MR Correa, H Halasz, EK Robinson, L O'Briain, C Vollmers, J Blau, S Katzman, MT McManus, S Carpenter High-Throughput CRISPR Screening Identifies Genes Involved in Macrophage Viability and Inflammatory Pathways Cell Reports, 2020-12-29;33(13):108541. 2020-12-29 [PMID: 33378675] (Mouse) |
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Mouse |
| F Botelho, A Dubey, EA Ayaub, R Park, A Yip, A Humbles, R Kolbeck, CD Richards IL-33 Mediates Lung Inflammation by the IL-6-Type Cytokine Oncostatin M Mediators of Inflammation, 2020-11-28;2020(0):4087315. 2020-11-28 [PMID: 33376451] (Mouse) |
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Mouse |
| O Dusek, A Fajstova, A Klimova, P Svozilkova, T Hrncir, M Kverka, S Coufal, J Slemin, H Tlaskalova, JV Forrester, J Heissigero Severity of Experimental Autoimmune Uveitis Is Reduced by Pretreatment with Live Probiotic Escherichia coli Nissle 1917 Cells, 2020-12-25;10(1):. 2020-12-25 [PMID: 33375578] (Mouse) |
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Mouse |
| A Fajstova, N Galanova, S Coufal, J Malkova, M Kostovcik, M Cermakova, H Pelantova, M Kuzma, B Sediva, T Hudcovic, T Hrncir, H Tlaskalova, M Kverka, K Kostovciko Diet Rich in Simple Sugars Promotes Pro-Inflammatory Response via Gut Microbiota Alteration and TLR4 Signaling Cells, 2020-12-16;9(12):. 2020-12-16 [PMID: 33339337] (Mouse) |
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Mouse |
| SS Chiang, LS Chen, CY Chu Active food ingredients production from cold pressed processing residues of Camellia oleifera and Camellia sinensis seeds for regulation of blood pressure and vascular function Chemosphere, 2020-12-11;267(0):129267. 2020-12-11 [PMID: 33338714] (Mouse) |
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Mouse |
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| A Taberner-C, Á Vinué, A Herrero-Ce, M Aguilar-Ba, JT Real, DJ Burks, S Martínez-H, H González-N Dapagliflozin Does Not Modulate Atherosclerosis in Mice with Insulin Resistance International Journal of Molecular Sciences, 2020-12-03;21(23):. 2020-12-03 [PMID: 33287201] (Mouse) |
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| MC Gestal, U Blas-Macha, HM Johnson, LN Rubin, KK Dewan, C Bryant, M Tiemeyer, ET Harvill Disrupting Bordetella Immunosuppression Reveals a Role for Eosinophils in Coordinating the Adaptive Immune Response in the Respiratory Tract Microorganisms, 2020-11-17;8(11):. 2020-11-17 [PMID: 33212993] (Mouse) |
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| KY Huang, MS Lin, TC Kuo, CL Chen, CC Lin, YC Chou, TL Chao, YH Pang, HC Kao, RS Huang, S Lin, SY Chang, PC Yang Humanized COVID-19 decoy antibody effectively blocks viral entry and prevents SARS-CoV-2 infection EMBO Mol Med, 2020-11-30;0(0):e12828. 2020-11-30 [PMID: 33159417] (Mouse) |
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| DM de Graaf, RJA Maas, SP Smeekens, E Eisenmesse, JS Redzic, MM Helsen, NE Powers, S Li, V Kalabokis, MS Gresnigt, LAB Joosten, CA Dinarello, FL van de Vee Human recombinant interleukin-38 suppresses inflammation in mouse models of local and systemic disease Cytokine, 2020-10-28;137(0):155334. 2020-10-28 [PMID: 33128926] (Mouse) |
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| P Mandal, AL McCormick, ES Mocarski TNF Signaling Dictates Myeloid and Non-Myeloid Cell Crosstalk to Execute MCMV-Induced Extrinsic Apoptosis Viruses, 2020-10-28;12(11):. 2020-10-28 [PMID: 33126536] (Mouse) |
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| JC DuBois, AK Ray, P Davies, B Shafit-Zag Anti-Axl antibody treatment reduces the severity of experimental autoimmune encephalomyelitis J Neuroinflammation, 2020-10-29;17(1):324. 2020-10-29 [PMID: 33121494] (Mouse) |
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| S Saito, N Kakizaki, A Okuno, T Maekawa, NM Tsuji Lactococcus lactis subsp. Cremoris C60 restores T Cell Population in Small Intestinal Lamina Propria in Aged Interleukin-18 Deficient Mice Nutrients, 2020-10-27;12(11):. 2020-10-27 [PMID: 33121026] (Mouse) |
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| FM de Jesus O, CF Gonçalves-, IMM de Moraes, PA Reis, VN Rocha, PT Bozza, AR Silva, HC de Castro Simvastatin Posttreatment Controls Inflammation and Improves Bacterial Clearance in Experimental Sepsis Mediators Inflamm, 2020-10-14;2020(0):1839762. 2020-10-14 [PMID: 33110395] (Mouse) |
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| JR Yaron, L Zhang, Q Guo, EA Awo, M Burgin, LN Schutz, N Zhang, J Kilbourne, J Daggett-Vo, KM Lowe, AR Lucas Recombinant Myxoma Virus-Derived Immune Modulator M-T7 Accelerates Cutaneous Wound Healing and Improves Tissue Remodeling Pharmaceutics, 2020-10-22;12(11):. 2020-10-22 [PMID: 33105865] (Mouse) |
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| AN Frone, CA Nicolae, MC Eremia, V Tofan, M Ghiurea, I Chiulan, E Radu, CM Damian, DM Panaitescu Low Molecular Weight and Polymeric Modifiers as Toughening Agents in Poly(3-Hydroxybutyrate) Films Polymers (Basel), 2020-10-22;12(11):. 2020-10-22 [PMID: 33105812] (Mouse) |
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| N Ito, H Takemoto, A Hasegawa, C Sugiyama, K Honma, T Nagai, Y Kobayashi, H Odaguchi Neuroinflammaging underlies emotional disturbances and circadian rhythm disruption in young male senescence-accelerated mouse prone 8 mice Exp Gerontol, 2020-10-16;0(0):111109. 2020-10-16 [PMID: 33069781] (Mouse) |
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| F Yang, P Huang, L Shi, F Liu, A Tang, S Xu Phoenixin 14 Inhibits High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Experimental Mice Drug Des Devel Ther, 2020-09-22;14(0):3865-3874. 2020-09-22 [PMID: 33061293] (Mouse) |
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| K Sato, A Tobo, C Mogi, M Tobo, N Yamane, M Tosaka, H Tomura, DS Im, F Okajima The protective role of proton-sensing TDAG8 in the brain injury in a mouse ischemia reperfusion model Sci Rep, 2020-10-14;10(1):17193. 2020-10-14 [PMID: 33057165] (Mouse) |
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| S Lee, S Kim, HY Kang, HR Lim, Y Kwon, M Jo, YM Jeon, SR Kim, K Kim, CM Ha, S Lee, HJ Kim The overexpression of TDP-43 in astrocytes causes neurodegeneration via a PTP1B-mediated inflammatory response J Neuroinflammation, 2020-10-14;17(1):299. 2020-10-14 [PMID: 33054766] (Mouse) |
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| PM Jordan, J Gerstmeier, S Pace, R Bilancia, Z Rao, F Börner, L Miek, Ó Gutiérrez-, V Arakandy, A Rossi, A Ialenti, C González-E, B Löffler, L Tuchscherr, CN Serhan, O Werz Staphylococcus aureus-Derived &alpha-Hemolysin Evokes Generation of Specialized Pro-resolving Mediators Promoting Inflammation Resolution Cell Rep, 2020-10-13;33(2):108247. 2020-10-13 [PMID: 33053344] (Mouse) |
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| XAMH van Dieren, T Sancerni, MC Alves-Guer, R Stienstra The role of uncoupling protein 2 in macrophages and its impact on obesity-induced adipose tissue inflammation and insulin resistance J Biol Chem, 2020-01-01;0(0):. 2020-01-01 [PMID: 33051201] (Mouse) |
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| V Hoghooghi, AL Palmer, A Frederick, Y Jiang, JE Merkens, A Balakrishn, TM Finlay, A Grubb, E Levy, P Gordon, FR Jirik, MD Nguyen, C Schuurmans, F Visser, SE Dunn, SS Ousman Cystatin C Plays a Sex-Dependent Detrimental Role in Experimental Autoimmune Encephalomyelitis Cell Rep, 2020-10-06;33(1):108236. 2020-10-06 [PMID: 33027652] (Mouse) |
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| YH Kim, MS Kwak, B Lee, JM Shin, S Aum, IH Park, MG Lee, JS Shin Secretory autophagy machinery and vesicular trafficking are involved in HMGB1 secretion Autophagy, 2020-10-05;0(0):1-18. 2020-10-05 [PMID: 33017561] (Mouse) |
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| J Sun, DL LaRock, EA Skowronski, JM Kimmey, J Olson, Z Jiang, AJ O'Donoghue, V Nizet, CN LaRock The Pseudomonas aeruginosa protease LasB directly activates IL-1&beta EBioMedicine, 2020-09-23;60(0):102984. 2020-09-23 [PMID: 32979835] (Mouse) |
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| N Virginkar, JK Christians Maternal Obesity Does Not Exacerbate the Effects of LPS Injection on Pregnancy Outcomes in Mice Biology, 2020-09-16;9(9):. 2020-09-16 [PMID: 32947926] (Mouse) |
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| E Susnik, P Taladriz-B, B Drasler, S Balog, A Petri-Fink, B Rothen-Rut Increased Uptake of Silica Nanoparticles in Inflamed Macrophages but Not upon Co-Exposure to Micron-Sized Particles Cells, 2020-09-15;9(9):. 2020-09-15 [PMID: 32942641] (Mouse) |
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| MIDDS Xisto, SS Santos, L Rossato, FSY Yoshikawa, RMT Haido, SR de Almeida, E Barreto-Be Peptidorhamnomannan from Lomentospora prolificans modulates the inflammatory response in macrophages infected with Candida albicans BMC Microbiol., 2020-08-06;20(1):245. 2020-08-06 [PMID: 32762645] (Mouse) |
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| J Wang, C Ortiz, L Fontenot, R Mukhopadhy, Y Xie, IKM Law, DQ Shih, SA Mattai, Z Li, HW Koon Elafin inhibits obesity, hyperglycemia, and liver steatosis in high-fat diet-treated male mice Sci Rep, 2020-07-30;10(1):12785. 2020-07-30 [PMID: 32733043] (Mouse) |
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| JJ Balic, H Albargy, K Luu, FJ Kirby, WSN Jayasekara, F Mansell, DJ Garama, D De Nardo, N Baschuk, C Louis, F Humphries, K Fitzgerald, E Latz, DJ Gough, A Mansell STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1&beta expression Nat Commun, 2020-07-30;11(1):3816. 2020-07-30 [PMID: 32732870] (Mouse) |
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| J Shin, OK Kim, S Kim, D Bae, J Lee, J Park, W Jun Immunomodulatory Effect of a Salvia plebeia R. Aqueous Extract in Forced Swimming Exercise-induced Mice Nutrients, 2020-07-28;12(8):. 2020-07-28 [PMID: 32731626] (Mouse) |
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| M Sohrabi, AM Floden, GD Manocha, MG Klug, CK Combs IGF-1R Inhibitor Ameliorates Neuroinflammation in an Alzheimer's Disease Transgenic Mouse Model Front Cell Neurosci, 2020-07-03;14(0):200. 2020-07-03 [PMID: 32719587] (Mouse) |
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| K Maruyama, H Kidoya, N Takemura, E Sugisawa, O Takeuchi, T Kondo, MMA Eid, H Tanaka, MM Martino, N Takakura, Y Takayama, S Akira, A Vandenbon, Y Kumagai Zinc Finger Protein St18 Protects against Septic Death by Inhibiting VEGF-A from Macrophages Cell Rep, 2020-07-14;32(2):107906. 2020-07-14 [PMID: 32668247] (Mouse) |
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| H Liu, X Yang, K Tang, T Ye, C Duan, P Lv, L Yan, X Wu, Z Chen, J Liu, Y Deng, G Zeng, J Xing, Z Ye, H Xu Sulforaphane elicts dual therapeutic effects on Renal Inflammatory Injury and crystal deposition in Calcium Oxalate Nephrocalcinosis Theranostics, 2020-06-05;10(16):7319-7334. 2020-06-05 [PMID: 32641994] (Mouse) |
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| A Jarneborn, M Mohammad, C Engdahl, Z Hu, M Na, A Ali, T Jin Tofacitinib treatment aggravates Staphylococcus aureus septic arthritis, but attenuates sepsis and enterotoxin induced shock in mice Sci Rep, 2020-07-02;10(1):10891. 2020-07-02 [PMID: 32616791] (Mouse) |
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| B Dunkhuntho, C Talabnin, M Murphy, K Thumanu, P Sittisart, T Hengpratom, G Eumkeb Intracellular ROS Scavenging and Anti-Inflammatory Activities of Oroxylum indicum Kurz (L.) Extract in LPS plus IFN-gamma-Activated RAW264.7 Macrophages Evid Based Complement Alternat Med, 2020-05-27;2020(0):7436920. 2020-05-27 [PMID: 32565874] (Mouse) |
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| T Sakaguchi, R Okumura, C Ono, D Okuzaki, T Kawai, Y Okochi, N Tanimura, M Murakami, H Kayama, E Umemoto, H Kioka, T Ohtani, Y Sakata, K Miyake, Y Okamura, Y Baba, K Takeda TRPM5 Negatively Regulates Calcium-Dependent Responses in Lipopolysaccharide-Stimulated B Lymphocytes Cell Rep, 2020-06-09;31(10):107755. 2020-06-09 [PMID: 32521253] (Mouse) |
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| A Wolf, M Herb, M Schramm, T Langmann The TSPO-NOX1 axis controls phagocyte-triggered pathological angiogenesis in the eye Nat Commun, 2020-06-01;11(1):2709. 2020-06-01 [PMID: 32483169] (Mouse) |
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| MC Montero, M Del Campo, M Bono, MV Simon, J Guerrero, N Lagos Neosaxitoxin Inhibits the Expression of Inflammation Markers of the M1 Phenotype in Macrophages Mar Drugs, 2020-05-27;18(6):. 2020-05-27 [PMID: 32471037] (Mouse) |
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| M Kim, K Jung, Y Ko, IS Kim, K Hwang, JH Jang, JE Shin, KI Park TNF-&alpha Pretreatment Improves the Survival and Function of Transplanted Human Neural Progenitor Cells Following Hypoxic-Ischemic Brain Injury Cells, 2020-05-11;9(5):. 2020-05-11 [PMID: 32403417] (Mouse) |
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| PE Negoro, S Xu, Z Dagher, A Hopke, JL Reedy, MB Feldman, NS Khan, AL Viens, NJ Alexander, NJ Atallah, AK Scherer, RA Dutko, J Jeffery, JF Kernien, JS Fites, JE Nett, BS Klein, JM Vyas, D Irimia, DB Sykes, MK Mansour Spleen Tyrosine Kinase Is a Critical Regulator of Neutrophil Responses to Candida Species MBio, 2020-05-12;11(3):. 2020-05-12 [PMID: 32398316] (Mouse) |
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| P Saha, X Xiao, Y Li, RM Golonka, AA Abokor, BS Yeoh, M Vijay-Kuma Distinct iron homeostasis in C57BL/6 and Balb/c mouse strains Physiol Rep, 2020-05-01;8(9):e14441. 2020-05-01 [PMID: 32385968] (Mouse) |
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| HC Lin, JY Lin M1 Polarization but Anti-LPS-Induced Inflammation and Anti-MCF-7 Breast Cancer Cell Growth Effects of Five Selected Polysaccharides Evid Based Complement Alternat Med, 2020-03-25;2020(0):9450246. 2020-03-25 [PMID: 32308723] (Mouse) |
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| P Silva, M de Almeida, J Silva, S Albino, R Espírito-S, M Lima, C Villarreal, R Moura, V Santos (E)-2-Cyano-3-(1H-Indol-3-yl)-N-Phenylacrylamide, a Hybrid Compound Derived from Indomethacin and Paracetamol: Design, Synthesis and Evaluation of the Anti-Inflammatory Potential Int J Mol Sci, 2020-04-08;21(7):. 2020-04-08 [PMID: 32276463] (Mouse) |
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| M Kittaka, T Yoshimoto, H Hoffman, ME Levitan, Y Ueki RANKL-independent osteoclastogenesis in the SH3BP2 cherubism mice Bone Rep, 2020-03-27;12(0):100258. 2020-03-27 [PMID: 32258251] (Mouse) |
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| V Garcia-Cas, G Marcial, L Albarracín, M Tomokiyo, P Clua, H Takahashi, H Kitazawa, A Garcia-Can, J Villena The Exopolysaccharide of Lactobacillus fermentum UCO-979C Is Partially Involved in Its Immunomodulatory Effect and Its Ability to Improve the Resistance against Helicobacter pylori Infection Microorganisms, 2020-03-27;8(4):. 2020-03-27 [PMID: 32230910] (Mouse) |
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| SH Kim, JH Hong, WK Yang, JH Geum, HR Kim, SY Choi, YM Kang, HJ An, YC Lee Herbal Combinational Medication of Glycyrrhiza glabra, Agastache rugosa Containing Glycyrrhizic Acid, Tilianin Inhibits Neutrophilic Lung Inflammation by Affecting CXCL2, Interleukin-17/STAT3 Signal Pathways in a Murine Model of COPD Nutrients, 2020-03-27;12(4):. 2020-03-27 [PMID: 32230838] (Mouse) |
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| LRC de Oliveir, LAN Mimura, TFC Fraga-Silv, LLW Ishikawa, AAH Fernandes, SFG Zorzella-P, A Sartori Calcitriol Prevents Neuroinflammation and Reduces Blood-Brain Barrier Disruption and Local Macrophage/Microglia Activation Front Pharmacol, 2020-03-12;11(0):161. 2020-03-12 [PMID: 32226379] (Mouse) |
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| E Zechendorf, CE O'Riordan, L Stiehler, N Wischmeyer, F Chiazza, D Collotta, B Denecke, S Ernst, G Müller-New, SM Coldewey, B Wissuwa, M Collino, TP Simon, T Schuerholz, C Stoppe, G Marx, C Thiemerman, L Martin Ribonuclease 1 attenuates septic cardiomyopathy and cardiac apoptosis in a murine model of polymicrobial sepsis JCI Insight, 2020-04-23;5(8):. 2020-04-23 [PMID: 32213712] (Mouse) |
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| A Famà, A Midiri, G Mancuso, C Biondo, G Lentini, R Galbo, MM Giardina, GV De Gaetano, L Romeo, G Teti, C Beninati Nucleic Acid-Sensing Toll-Like Receptors Play a Dominant Role in Innate Immune Recognition of Pneumococci MBio, 2020-03-24;11(2):. 2020-03-24 [PMID: 32209688] (Mouse) |
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| KD Curtis, PR Smith, HW Despres, JP Snyder, TC Hogan, PD Rodriguez, E Amiel Glycogen Metabolism Supports Early Glycolytic Reprogramming and Activation in Dendritic Cells in Response to Both TLR and Syk-Dependent CLR Agonists Cells, 2020-03-14;9(3):. 2020-03-14 [PMID: 32183271] (Mouse) |
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| RDC da Cunha d, MM Cruz, TM de Farias, VS da Silva, J de Jesus S, MM Telles, MIC Alonso-Val Fish oil reverses metabolic syndrome, adipocyte dysfunction, and altered adipokines secretion triggered by high-fat diet-induced obesity Physiol Rep, 2020-02-01;8(4):e14380. 2020-02-01 [PMID: 32109344] (Mouse) |
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| TH Yeh, JY Lin Acorus gramineusand and Euodia ruticarpa Steam Distilled Essential Oils Exert Anti-Inflammatory Effects Through Decreasing Th1/Th2 and Pro-/Anti-Inflammatory Cytokine Secretion Ratios In Vitro Biomolecules, 2020-02-19;10(2):. 2020-02-19 [PMID: 32093087] (Mouse) |
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| A Nemmar, S Al-Salam, S Beegam, P Yuvaraju, NE Zaaba, J Yasin, BH Ali Waterpipe Tobacco Smoke Inhalation Triggers Thrombogenicity, Cardiac Inflammation and Oxidative Stress in Mice: Effects of Flavouring Int J Mol Sci, 2020-02-14;21(4):. 2020-02-14 [PMID: 32075078] (Mouse) |
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| XAMH van Dieren, MA de la Rosa, A Georgiadi, F Mattijssen, W Dijk, M van Weeghe, R Singh, JW Borst, R Stienstra, S Kersten HILPDA Uncouples Lipid Droplet Accumulation in Adipose Tissue Macrophages from Inflammation and Metabolic Dysregulation Cell Rep, 2020-02-11;30(6):1811-1822.e6. 2020-02-11 [PMID: 32049012] (Mouse) |
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| H Ma, J Wang, X Zhao, T Wu, Z Huang, D Chen, Y Liu, G Ouyang Periostin Promotes Colorectal Tumorigenesis through Integrin-FAK-Src Pathway-Mediated YAP/TAZ Activation Cell Rep, 2020-01-21;30(3):793-806.e6. 2020-01-21 [PMID: 31968254] (Mouse) |
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| A Carreras-G, D Barriales, A Palacios, M Montesinos, N Navasa, M Azkargorta, A Peña-Cearr, J Tomás-Cort, I Escobes, MA Pascual-It, J Hradiská, J Kopecký, D Gil-Carton, R Prados-Ros, L Abecia, E Atondo, I Martín, A Pellón, F Elortza, H Rodríguez, J Anguita Regulation of macrophage activity by surface receptors contained within Borrelia burgdorferi-enriched phagosomal fractions PLoS Pathog., 2019-11-18;15(11):e1008163. 2019-11-18 [PMID: 31738806] (Mouse) |
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| T Jin, M Mohammad, Z Hu, Y Fei, ERB Moore, R Pullerits, A Ali A novel mouse model for septic arthritis induced by Pseudomonas aeruginosa Sci Rep, 2019-11-14;9(1):16868. 2019-11-14 [PMID: 31727989] (Mouse) |
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| MJR Ruigrok, J Tomar, HW Frijlink, BN Melgert, WLJ Hinrichs, P Olinga The effects of oxygen concentration on cell death, anti-oxidant transcription, acute inflammation, and cell proliferation in precision-cut lung slices Sci Rep, 2019-11-07;9(1):16239. 2019-11-07 [PMID: 31700101] (Mouse) |
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| M Torvell, DW Hampton, P Connick, AMJ MacLullich, C Cunningham, S Chandran A single systemic inflammatory insult causes acute motor deficits and accelerates disease progression in a mouse model of human tauopathy Alzheimers Dement (N Y), 2019-10-09;5(0):579-591. 2019-10-09 [PMID: 31650014] (Mouse) |
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| D Lou, J Wang, X Wang miR-124 ameliorates depressive-like behavior by targeting STAT3 to regulate microglial activation Mol. Cell. Probes, 2019-10-15;0(0):101470. 2019-10-15 [PMID: 31626919] (Mouse) |
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| Y Song, HY Jeong, JK Lee, YS Choi, DO Kim, D Jang, CS Park, S Maeng, H Kang Enzyme Treatment Alters the Anti-Inflammatory Activity of the Water Extract of Wheat Germ In Vitro and In Vivo Nutrients, 2019-10-16;11(10):. 2019-10-16 [PMID: 31623257] (Mouse) |
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| MM Hughes, A Hooftman, S Angiari, P Tummala, Z Zaslona, MC Runtsch, AF McGettrick, CE Sutton, C Diskin, M Rooke, S Takahashi, S Sundararaj, MG Casarotto, JE Dahlstrom, EM Palsson-Mc, SC Corr, KHG Mills, RJS Preston, N Neamati, Y Xie, JB Baell, PG Board, LAJ O'Neill Glutathione Transferase Omega-1 Regulates NLRP3 Inflammasome Activation through NEK7 Deglutathionylation Cell Rep, 2019-10-01;29(1):151-161.e5. 2019-10-01 [PMID: 31577945] (Mouse) |
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| J Periselner, G Ercoli, T Pollard, S Chimalapat, E Camberlein, G Szylar, C Hyams, G Tomlinson, FC Petersen, RA Floto, M Noursadegh, JS Brown Relative Contributions of Extracellular and Internalized Bacteria to Early Macrophage Proinflammatory Responses to Streptococcus pneumoniae MBio, 2019-09-24;10(5):. 2019-09-24 [PMID: 31551336] (Mouse) |
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| I Chiulan, DM Panaitescu, ER Radu, AN Frone, RA Gabor, CA Nicolae, G Jinescu, V Tofan, G Chinga-Car Comprehensive characterization of silica-modified silicon rubbers J Mech Behav Biomed Mater, 2019-09-10;101(0):103427. 2019-09-10 [PMID: 31539735] (Mouse) |
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| Y Lin, B Li, X Yang, T Liu, T Shi, B Deng, Y Zhang, L Jia, Z Jiang, R He Non-hematopoietic STAT6 induces epithelial tight junction dysfunction and promotes intestinal inflammation and tumorigenesis Mucosal Immunol, 2019-09-18;0(0):. 2019-09-18 [PMID: 31534167] (Mouse) |
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| L Yue, M Yan, ML Tremblay, TJ Lin, H Li, T Yang, X Song, T Xie, Z Xie PTP1B negatively regulates nitric oxide-mediated Pseudomonas aeruginosa killing by neutrophils PLoS ONE, 2019-09-18;14(9):e0222753. 2019-09-18 [PMID: 31532798] (Mouse) |
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| B Liu, AP Henry, S Azimi, S Miller, FK Lee, JC Lee, K Probert, MI Kotlikoff, I Sayers, IP Hall Exposure to lipopolysaccharide (LPS) reduces contractile response of small airways from GSTCD-/- mice PLoS ONE, 2019-09-12;14(9):e0221899. 2019-09-12 [PMID: 31513609] (Mouse) |
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| PM Thwe, DI Fritz, JP Snyder, PR Smith, KD Curtis, A O'Donnell, NA Galasso, LA Sepaniac, BJ Adamik, LR Hoyt, PD Rodriguez, TC Hogan, AF Schmidt, ME Poynter, E Amiel Syk-dependent glycolytic reprogramming in dendritic cells regulates IL-1 β production to β-glucan ligands in a TLR-independent manner J. Leukoc. Biol., 2019-09-11;0(0):. 2019-09-11 [PMID: 31509298] (Mouse) |
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| DR Lacerda, KA Costa, ALM Silveira, DF Rodrigues, AN Silva, JL Sabino, V Pinho, GB Menezes, DD Soares, MM Teixeira, AVM Ferreira Role of adipose tissue inflammation in fat pad loss induced by fasting in lean and mildly obese mice J. Nutr. Biochem., 2019-06-21;72(0):108208. 2019-06-21 [PMID: 31473506] (Mouse) |
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| S De, DR Whiten, FS Ruggeri, C Hughes, M Rodrigues, DI Sideris, CG Taylor, FA Aprile, S Muylderman, TPJ Knowles, M Vendruscol, C Bryant, K Blennow, I Skoog, S Kern, H Zetterberg, D Klenerman Soluble aggregates present in cerebrospinal fluid change in size and mechanism of toxicity during Alzheimer's disease progression Acta Neuropathol Commun, 2019-07-26;7(1):120. 2019-07-26 [PMID: 31349874] (Mouse) |
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| SU Rehman, M Ikram, N Ullah, SI Alam, HY Park, H Badshah, K Choe, MO Kim Neurological Enhancement Effects of Melatonin against Brain Injury-Induced Oxidative Stress, Neuroinflammation, and Neurodegeneration via AMPK/CREB Signaling Cells, 2019-07-21;8(7):. 2019-07-21 [PMID: 31330909] (Mouse) |
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| L Hu, ED Zachariae, UG Larsen, F Vilhardt, SV Petersen The dynamic uptake and release of SOD3 from intracellular stores in macrophages modulates the inflammatory response Redox Biol, 2019-07-02;26(0):101268. 2019-07-02 [PMID: 31326693] (Mouse) |
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Mouse |
| JD Bailey, M Diotallevi, T Nicol, E McNeill, A Shaw, S Chuaiphich, A Hale, A Starr, M Nandi, E Stylianou, H McShane, S Davis, R Fischer, BM Kessler, J McCullagh, KM Channon, MJ Crabtree Nitric Oxide Modulates Metabolic Remodeling in Inflammatory Macrophages through TCA Cycle Regulation and Itaconate Accumulation Cell Rep, 2019-07-02;28(1):218-230.e7. 2019-07-02 [PMID: 31269442] (Mouse, Transgenic Mouse) |
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| B Burger, CMC Kühl, T Candreva, RDS Cardoso, JR Silva, BG Castelucci, SR Consonni, HL Fisk, PC Calder, MAR Vinolo, HG Rodrigues Oral administration of EPA-rich oil impairs collagen reorganization due to elevated production of IL-10 during skin wound healing in mice Sci Rep, 2019-06-24;9(1):9119. 2019-06-24 [PMID: 31235718] (Mouse) |
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| M Mohammad, MT Nguyen, C Engdahl, M Na, A Jarneborn, Z Hu, A Karlsson, R Pullerits, A Ali, F Götz, T Jin The YIN and YANG of lipoproteins in developing and preventing infectious arthritis by Staphylococcus aureus PLoS Pathog., 2019-06-21;15(6):e1007877. 2019-06-21 [PMID: 31226163] (Mouse) |
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| A Nemmar, S Al-Salam, S Beegam, P Yuvaraju, BH Ali Waterpipe Smoke Exposure Triggers Lung Injury and Functional Decline in Mice: Protective Effect of Gum Arabic Oxid Med Cell Longev, 2019-04-21;2019(0):8526083. 2019-04-21 [PMID: 31178975] (Mouse) |
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| G Kalugotla, L He, KJ Weber, S Daemen, A Reller, B Razani, JD Schilling Frontline Science: Acyl-CoA synthetase 1 exacerbates lipotoxic inflammasome activation in primary macrophages J. Leukoc. Biol., 2019-06-05;0(0):. 2019-06-05 [PMID: 31166619] (Mouse) |
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| PS Sung, TF Huang, SL Hsieh Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 Nat Commun, 2019-06-03;10(1):2402. 2019-06-03 [PMID: 31160588] (Mouse) |
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| VN Camargos, G Foureaux, DC Medeiros, VT da Silveir, CM Queiroz-Ju, ALB Matosinhos, AFA Figueiredo, CDF Sousa, TP Moreira, VF Queiroz, ACF Dias, KTO Santana, I Passos, ALCV Real, LC Silva, FAG Mourão, NT Wnuk, MAP Oliveira, S Macari, T Silva, GP Garlet, JA Jackman, FM Soriani, MFD Moraes, EMAM Mendes, FM Ribeiro, GMJ Costa, AL Teixeira, NJ Cho, ACP Oliveira, MM Teixeira, VV Costa, DG Souza In-depth characterization of congenital Zika syndrome in immunocompetent mice: Antibody-dependent enhancement and an antiviral peptide therapy EBioMedicine, 2019-05-23;0(0):. 2019-05-23 [PMID: 31130472] (Mouse) |
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| M Alves, L De Diego G, G Conte, EM Jimenez-Ma, B D'Orsi, A Sanz-Rodri, JH Prehn, DC Henshall, T Engel Context-specific switch from anti- to pro-epileptogenic function of the P2Y1 receptor in experimental epilepsy J. Neurosci., 2019-05-02;0(0):. 2019-05-02 [PMID: 31048325] (Mouse) |
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| S Vander Bek, JC de Vries, B Meier-Schi, P Meyer, D Jiang, A Sindrilaru, FF Ferreira, A Hainzl, S Schatz, J Muschhamme, NJ Scheurmann, P Kampilafko, AM Seitz, L Dürselen, A Ignatius, MA Kluth, C Ganss, M Wlaschek, K Singh, P Maity, NY Frank, MH Frank, K Scharffett Newly defined ABCB5+ dermal mesenchymal stem cells promote healing of chronic iron overload wounds via secretion of interleukin-1 receptor antagonist Stem Cells, 2019-05-13;0(0):. 2019-05-13 [PMID: 31002437] (Mouse) |
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Mouse |
| J Aguilera-H, M García-Qui, R Romero-Flo, MJ McConnell, F Ramos-Mora A Live Salmonella Vaccine Delivering PcrV through the Type III Secretion System Protects against Pseudomonas aeruginosa mSphere, 2019-04-17;4(2):. 2019-04-17 [PMID: 30996108] (Mouse) |
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Mouse |
| JL Fachi, JS Felipe, LP Pral, BK da Silva, RO Corrêa, MCP de Andrade, DM da Fonseca, PJ Basso, NOS Câmara, ÉL de Sales E, F Dos Santos, SES Guima, AM Thomas, JC Setubal, YT Magalhães, FL Forti, T Candreva, HG Rodrigues, MB de Jesus, SR Consonni, ADS Farias, P Varga-Weis, MAR Vinolo Butyrate Protects Mice from Clostridium difficile-Induced Colitis through an HIF-1-Dependent Mechanism Cell Rep, 2019-04-16;27(3):750-761.e7. 2019-04-16 [PMID: 30995474] (Mouse) |
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| I Misumi, J Starmer, T Uchimura, MA Beck, T Magnuson, JK Whitmire Obesity Expands a Distinct Population of T Cells in Adipose Tissue and Increases Vulnerability to Infection Cell Rep, 2019-04-09;27(2):514-524.e5. 2019-04-09 [PMID: 30970254] (Mouse) |
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| VB Lê, J Dubois, C Couture, MH Cavanagh, O Uyar, A Pizzorno, M Rosa-Calat, MÈ Hamelin, G Boivin Human metapneumovirus activates NOD-like receptor protein 3 inflammasome via its small hydrophobic protein which plays a detrimental role during infection in mice PLoS Pathog., 2019-04-09;15(4):e1007689. 2019-04-09 [PMID: 30964929] (Mouse) |
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| Z Moosova, M Pekarova, LS Sindlerova, O Vasicek, L Kubala, L Blaha, O Adamovsky Immunomodulatory effects of cyanobacterial toxin cylindrospermopsin on innate immune cells Chemosphere, 2019-03-29;226(0):439-446. 2019-03-29 [PMID: 30951938] (Mouse) |
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| M McMillin, S Grant, G Frampton, AD Petrescu, E Williams, B Jefferson, A Thomas, A Brahmarout, S DeMorrow Elevated circulating TGF?1 during acute liver failure activates TGF?R2 on cortical neurons and exacerbates neuroinflammation and hepatic encephalopathy in mice J Neuroinflammation, 2019-04-02;16(1):69. 2019-04-02 [PMID: 30940161] (Mouse) |
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| AML Scantleber, M Uil, LM Butter, R Poelman, N Claessen, SE Girardin, S Florquin, JJTH Roelofs, JC Leemans NLRX1 does not play a role in diabetes nor the development of diabetic nephropathy induced by multiple low doses of streptozotocin PLoS ONE, 2019-03-25;14(3):e0214437. 2019-03-25 [PMID: 30908533] (Mouse) |
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| TA Diniz, JCJ Aquino Jún, FC Mosele, C Cabral-San, EA Lima Junio, AAS Teixeira, FS Lira, JC Rosa Neto Exercise-induced AMPK activation and IL-6 muscle production are disturbed in adiponectin knockout mice Cytokine, 2019-03-20;119(0):71-80. 2019-03-20 [PMID: 30903866] (Mouse) |
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| G Thomi, D Surbek, V Haesler, M Joerger-Me, A Schoeberle Exosomes derived from umbilical cord mesenchymal stem cells reduce microglia-mediated neuroinflammation in perinatal brain injury Stem Cell Res Ther, 2019-03-21;10(1):105. 2019-03-21 [PMID: 30898154] (Mouse) |
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| MR Scheenstra, M van den Be, JLM Tjeerdsma-, VAF Schneider, SR Ordonez, A van Dijk, EJA Veldhuizen, HP Haagsman Cathelicidins PMAP-36, LL-37 and CATH-2 are similar peptides with different modes of action Sci Rep, 2019-03-18;9(1):4780. 2019-03-18 [PMID: 30886247] (Mouse) |
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| Z Gong, J Huang, B Xu, Z Ou, L Zhang, X Lin, X Ye, X Kong, D Long, X Sun, X He, L Xu, Q Li, A Xuan Urolithin A attenuates memory impairment and neuroinflammation in APP/PS1 mice J Neuroinflammation, 2019-03-14;16(1):62. 2019-03-14 [PMID: 30871577] (Mouse) |
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| KD Passalacqu, J Lu, I Goodfellow, AO Kolawole, JR Arche, RJ Maddox, KE Carnahan, MXD O'Riordan, CE Wobus Glycolysis Is an Intrinsic Factor for Optimal Replication of a Norovirus MBio, 2019-03-12;10(2):. 2019-03-12 [PMID: 30862747] (Mouse) |
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| A Nemmar, S Al-Salam, S Beegam, P Yuvaraju, BH Ali Gum Arabic Ameliorates Impaired Coagulation and Cardiotoxicity Induced by Water-Pipe Smoke Exposure in Mice Front Physiol, 2019-02-25;10(0):53. 2019-02-25 [PMID: 30858803] (Mouse) |
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| OM Finucane, J Sugrue, A Rubio-Arai, MV Guillot-Se, MA Lynch The NLRP3 inflammasome modulates glycolysis by increasing PFKFB3 in an IL-1?-dependent manner in macrophages Sci Rep, 2019-03-11;9(1):4034. 2019-03-11 [PMID: 30858427] (Mouse) |
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| AR Burmeister, MB Johnson, JJ Yaemmongko, I Marriott Murine astrocytes produce IL-24 and are susceptible to the immunosuppressive effects of this cytokine J Neuroinflammation, 2019-03-02;16(1):55. 2019-03-02 [PMID: 30825881] (Mouse) |
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| AC Luissint, HC Williams, W Kim, S Flemming, V Azcutia, RS Hilgarth, MNO Leary, TL Denning, A Nusrat, CA Parkos Macrophage-dependent neutrophil recruitment is impaired under conditions of increased intestinal permeability in JAM-A-deficient mice Mucosal Immunol, 2019-02-11;0(0):. 2019-02-11 [PMID: 30745566] (Mouse) |
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Mouse |
| AS Ernst, LI Böhler, AM Hagenston, A Hoffmann, S Heiland, C Sticht, M Bendszus, M Hecker, H Bading, HH Marti, T Korff, R Kunze EphB2-dependent signaling promotes neuronal excitotoxicity and inflammation in the acute phase of ischemic stroke Acta Neuropathol Commun, 2019-02-05;7(1):15. 2019-02-05 [PMID: 30722785] (Mouse) |
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Mouse |
| N Pacienza, RH Lee, EH Bae, DK Kim, Q Liu, DJ Prockop, G Yannarelli In�Vitro Macrophage Assay Predicts the In�Vivo Anti-inflammatory Potential of Exosomes from Human Mesenchymal Stromal Cells Mol Ther Methods Clin Dev, 2018-12-15;13(0):67-76. 2018-12-15 [PMID: 30719485] (Mouse) |
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Mouse |
| JH Nho, AH Kim, HK Jung, MJ Lee, JH Jang, BD Yang, HJ Lee, KH Lee, KW Woo, HW Cho Water Extract of Acori Graminei Rhizoma Attenuates Features of Rheumatoid Arthritis in DBA/1 Mice Evid Based Complement Alternat Med, 2019-01-01;2019(0):3637453. 2019-01-01 [PMID: 30713571] (Mouse) |
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Mouse |
| L Whitesell, N Robbins, DS Huang, CA McLellan, T Shekhar-Gu, EV LeBlanc, CS Nation, R Hui, A Hutchinson, C Collins, S Chatterjee, R Trilles, JL Xie, DJ Krysan, S Lindquist, JA Porco, U Tatu, LE Brown, J Pizarro, LE Cowen Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus Nat Commun, 2019-01-24;10(1):402. 2019-01-24 [PMID: 30679438] (Mouse) |
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Mouse |
| H Cui, S Banerjee, S Guo, N Xie, J Ge, D Jiang, M Zörnig, VJ Thannickal, G Liu Long noncoding RNA Malat1 regulates differential activation of macrophage and response to lung injury JCI Insight, 2019-02-21;0(0):. 2019-02-21 [PMID: 30676324] (Mouse) |
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Mouse |
| DC Arruda, IJ Gonzalez, S Finet, L Cordova, V Trichet, GF Andrade, C Hoffmann, P Bigey, WA de Almeida, A Da Silva C, A Malachias, V Escriou Modifying internal organization and surface morphology of siRNA lipoplexes by sodium alginate addition for efficient siRNA delivery J Colloid Interface Sci, 2019-01-14;540(0):342-353. 2019-01-14 [PMID: 30660791] (Mouse) |
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Mouse |
| K Ni, A Gill, D Cao, K Koike, KS Schweitzer, S Garantziot, I Petrache Intravascular heavy chain-modification of hyaluronan during endotoxic shock Biochem Biophys Rep, 2018-12-26;17(0):114-121. 2018-12-26 [PMID: 30623115] (Mouse) |
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Mouse |
| L Subedi, SH Baek, SY Kim Genetically Engineered Resveratrol-Enriched Rice Inhibits Neuroinflammation in Lipopolysaccharide-Activated BV2 Microglia Via Downregulating Mitogen-Activated Protein Kinase-Nuclear Factor Kappa B Signaling Pathway Oxid Med Cell Longev, 2018-12-03;2018(0):8092713. 2018-12-03 [PMID: 30622674] (Mouse) |
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Mouse |
| JH Nho, HJ Lee, HK Jung, JH Jang, KH Lee, AH Kim, TK Sung, HW Cho Effect of Saururus chinensis leaves extract on type II collagen-induced arthritis mouse model BMC Complement Altern Med, 2019-01-03;19(1):2. 2019-01-03 [PMID: 30606189] (Mouse) |
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Mouse |
| M Klier, S Gorressen, MA Urbahn, D Barbosa, M Ouwens, JW Fischer, M Elvers Enzymatic Activity Is Not Required for Phospholipase D Mediated TNF-? Regulation and Myocardial Healing Front Physiol, 2018-11-29;9(0):1698. 2018-11-29 [PMID: 30555342] (Mouse) |
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Mouse |
| H Leelayuwap, S Ruchirawat, S Boonyaratt Rapid synthesis and immunogenicity of mycobacterial (1?5)-?-d-arabinofuranan Carbohydr Polym, 2018-10-24;206(0):262-272. 2018-10-24 [PMID: 30553321] (Mouse) |
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Mouse |
| IM Medeiros-d, CF Gonçalves-, ARM Kurz, FMJ Oliveira, VHP de Abreu, RC Torres, VF Carvalho, V Estato, PT Bozza, M Sperandio, HC de Castro-, AR Silva Omega-9 Oleic Acid, the Main Compound of Olive Oil, Mitigates Inflammation during Experimental Sepsis Oxid Med Cell Longev, 2018-11-13;2018(0):6053492. 2018-11-13 [PMID: 30538802] (Mouse) |
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Mouse |
| V Ciancarell, L Lembo-Fazi, I Paciello, AK Bruno, S Jaillon, S Berardi, M Barbagallo, S Meron-Suda, D Cohen, A Molinaro, G Rossi, C Garlanda, ML Bernardini Role of a fluid-phase PRR in fighting an intracellular pathogen: PTX3 in Shigella infection PLoS Pathog., 2018-12-07;14(12):e1007469. 2018-12-07 [PMID: 30532257] (Mouse) |
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Mouse |
| JW Lee, H Nam, LE Kim, Y Jeon, H Min, S Ha, Y Lee, SY Kim, SJ Lee, EK Kim, SW Yu TLR4 (toll-like receptor 4) activation suppresses autophagy through inhibition of FOXO3 and impairs phagocytic capacity of microglia Autophagy, 2018-12-13;0(0):. 2018-12-13 [PMID: 30523761] (Mouse) |
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Mouse |
| AS Meena, PK Shukla, P Sheth, R Rao EGF receptor plays a role in the mechanism of glutamine-mediated prevention of alcohol-induced gut barrier dysfunction and liver injury J. Nutr. Biochem., 2018-11-06;64(0):128-143. 2018-11-06 [PMID: 30502657] (Mouse) |
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Mouse |
| TM Nordgren, AJ Heires, J Zempleni, BJ Swanson, C Wichman, DJ Romberger Bovine milk-derived extracellular vesicles enhance inflammation and promote M1 polarization following agricultural dust exposure in mice J. Nutr. Biochem., 2018-11-03;64(0):110-120. 2018-11-03 [PMID: 30476878] (Mouse) |
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Mouse |
| JW Nicholatos, AB Francisco, CA Bender, T Yeh, FJ Lugay, JE Salazar, C Glorioso, S Libert Nicotine promotes neuron survival and partially protects from Parkinson's disease by suppressing SIRT6 Acta Neuropathol Commun, 2018-11-08;6(1):120. 2018-11-08 [PMID: 30409187] (Mouse) |
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| CW Hui, X Song, F Ma, X Shen, K Herrup Ibuprofen prevents progression of ataxia telangiectasia symptoms in ATM-deficient mice J Neuroinflammation, 2018-11-06;15(1):308. 2018-11-06 [PMID: 30400801] (Mouse) |
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Mouse |
| P Saz-Leal, C Del Fresno, P Brandi, S Martínez-C, OM Dungan, JD Chisholm, WG Kerr, D Sancho Targeting SHIP-1 in Myeloid Cells Enhances Trained Immunity and Boosts Response to Infection Cell Rep, 2018-10-30;25(5):1118-1126. 2018-10-30 [PMID: 30380404] (Mouse) |
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Mouse |
| LP Leroux, M Nasr, R Valanparam, M Tam, BA Rosa, E Siciliani, DE Hill, DS Zarlenga, M Jaramillo, JV Weinstock, TG Geary, MM Stevenson, JF Urban, M Mitreva, A Jardim Analysis of the Trichuris suis excretory/secretory proteins as a function of life cycle stage and their immunomodulatory properties Sci Rep, 2018-10-29;8(1):15921. 2018-10-29 [PMID: 30374177] (Mouse) |
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Mouse |
| F Fattahi, MW Russell, EA Malan, M Parlett, E Abe, FS Zetoune, PA Ward Harmful Roles of TLR3 and TLR9 in Cardiac Dysfunction Developing during Polymicrobial Sepsis Biomed Res Int, 2018-09-30;2018(0):4302726. 2018-09-30 [PMID: 30364002] (Mouse) |
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| RF Righetti, TM Dos Santos, LDN Camargo, LRCRB Aristótele, S Fukuzaki, FCR de Souza, FPR Santana, MVR de Agrela, MM Cruz, MIC Alonso-Val, IS Genaro, BM Saraiva-Ro, EA Leick, MA Martins, CM Prado, IFLC Tibério Protective Effects of Anti-IL17 on Acute Lung Injury Induced by LPS in Mice Front Pharmacol, 2018-10-04;9(0):1021. 2018-10-04 [PMID: 30337870] (Mouse) |
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| C Wang, KA Bauckman, ASB Ross, JW Symington, MM Ligon, G Scholtes, A Kumar, HW Chang, J Twentyman, BE Fashemi, RJ Xavier, IU Mysorekar A non-canonical autophagy-dependent role of the ATG16L1T300A variant in urothelial vesicular trafficking and uropathogenic Escherichia coli persistence Autophagy, 2018-11-08;0(0):. 2018-11-08 [PMID: 30335568] (Mouse) |
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Mouse |
| C Dollt, J Michel, L Kloss, S Melchers, K Schledzews, K Becker, A Sauer, A Krewer, F Koll, A Schmieder The novel immunoglobulin super family receptor SLAMF9 identified in TAM of murine and human melanoma influences pro-inflammatory cytokine secretion and migration Cell Death Dis, 2018-09-19;9(10):939. 2018-09-19 [PMID: 30232321] (Mouse) |
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Mouse |
| NC Howard, ND Marin, M Ahmed, BA Rosa, J Martin, M Bambouskov, A Sergushich, E Loginichev, N Kurepina, J Rangel-Mor, L Chen, BN Kreiswirth, RS Klein, JM Balada-Lla, JB Torrelles, GK Amarasingh, M Mitreva, MN Artyomov, FF Hsu, B Mathema, SA Khader Mycobacterium tuberculosis carrying a rifampicin drug resistance mutation reprograms macrophage metabolism through cell wall lipid changes Nat Microbiol, 2018-09-17;0(0):. 2018-09-17 [PMID: 30224802] (Mouse) |
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| HR Kim, Y Mun, KS Lee, YJ Park, JS Park, JH Park, BN Jeon, CH Kim, Y Jun, YM Hyun, M Kim, SM Lee, CS Park, SH Im, CD Jun T cell microvilli constitute immunological synaptosomes that carry messages to antigen-presenting cells Nat Commun, 2018-09-07;9(1):3630. 2018-09-07 [PMID: 30194420] (Mouse) |
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| N Eissa, P Jayaprakas, S Azimullah, SK Ojha, M Al-Houqani, FY Jalal, D ?a?ewska, K Kie?-Konon, B Sadek The histamine H3R antagonist DL77 attenuates autistic behaviors in a prenatal valproic acid-induced mouse model of autism Sci Rep, 2018-08-30;8(1):13077. 2018-08-30 [PMID: 30166610] (Mouse) |
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Mouse |
| DN Silva, BSF Souza, CM Azevedo, JF Vasconcelo, PG de Jesus, MS Feitoza, CS Meira, GB Carvalho, BR Cavalcante, R Ribeiro-Do, MBP Soares IGF-1-Overexpressing Mesenchymal Stem/Stromal Cells Promote Immunomodulatory and Proregenerative Effects in Chronic Experimental Chagas Disease Stem Cells Int, 2018-07-24;2018(0):9108681. 2018-07-24 [PMID: 30140292] (Mouse) |
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| S Cicko, TC Köhler, CK Ayata, T Müller, N Ehrat, A Meyer, M Hossfeld, A Zech, F Di Virgili, M Idzko Extracellular ATP is a danger signal activating P2X7 receptor in a LPS mediated inflammation (ARDS/ALI) Oncotarget, 2018-07-17;9(55):30635-30648. 2018-07-17 [PMID: 30093975] (Mouse) |
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| M Blank, T Bashi, J Lachnish, D Ben-Ami-Sh, O Shovman, M Fridkin, M Eisenstein, A Volkov, I Barshack, Y Shoenfeld Helminths-based bi-functional molecule, tuftsin-phosphorylcholine (TPC), ameliorates an established murine arthritis PLoS ONE, 2018-08-08;13(8):e0200615. 2018-08-08 [PMID: 30089122] (Mouse) |
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| K Ren, T Jiang, HF Zhou, Y Liang, GJ Zhao Apigenin Retards Atherogenesis by Promoting ABCA1-Mediated Cholesterol Efflux and Suppressing Inflammation Cell. Physiol. Biochem., 2018-07-05;47(5):2170-2184. 2018-07-05 [PMID: 29975943] (Mouse) |
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| C Delyea, N Bozorgmehr, P Koleva, G Dunsmore, S Shahbaz, V Huang, S Elahi CD71+ Erythroid Suppressor Cells Promote Fetomaternal Tolerance through Arginase-2 and PDL-1 J. Immunol., 2018-05-07;0(0):. 2018-05-07 [PMID: 29735482] (Mouse) |
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| J Zhang, D Malo, R Mott, JJ Panthier, X Montagutel, J Jaubert Identification of new loci involved in the host susceptibility to Salmonella Typhimurium in collaborative cross mice BMC Genomics, 2018-04-27;19(1):303. 2018-04-27 [PMID: 29703142] (Mouse) |
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| Angelica Martins Batista, Lucia Elena Alvarado-, Silvia Marinho Alves, Gloria Melo, Isabela Resende Pereira, Leonardo Alexandre de Sou Ruivo, Andrea Alice Da Silva, Daniel Gibaldi, Thayse Do E S Protásio Da Silva, Virginia Maria Barros De Lorena, Adriene Siqueira De Melo, Ana Karine De Araújo, Michelle Da Silva Barros, Vláudia Maria Assis Costa, Cynthia C Cardoso, Antonio G Pacheco, Cristina Carrazzon, Wilson Oliveira, Milton Ozório Moraes, Joseli Lannes-Vi Genetic Polymorphism at CCL5 Is Associated With Protection in Chagas' Heart Disease: Antagonistic Participation of CCR1+ and CCR5+ Cells in Chronic Chagasic Cardiomyopathy. Frontiers in Immunology, 2018-04-11;0(0):1664-3224. 2018-04-11 [PMID: 29696014] (Mouse) |
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| Y Hayama, T Kimura, Y Takeda, S Nada, S Koyama, H Takamatsu, S Kang, D Ito, Y Maeda, M Nishide, S Nojima, H Sarashina-, T Hosokawa, Y Kinehara, Y Kato, T Nakatani, Y Nakanishi, T Tsuda, T Koba, M Okada, A Kumanogoh Lysosomal Protein Lamtor1 Controls Innate Immune Responses via Nuclear Translocation of Transcription Factor EB J. Immunol., 2018-04-23;0(0):. 2018-04-23 [PMID: 29686050] (Mouse) |
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| GI Lancaster, KG Langley, NA Berglund, HL Kammoun, S Reibe, E Estevez, J Weir, NA Mellett, G Pernes, JRW Conway, MKS Lee, P Timpson, AJ Murphy, SL Masters, S Gerondakis, N Bartonicek, DC Kaczorowsk, ME Dinger, PJ Meikle, PJ Bond, MA Febbraio Evidence that TLR4 Is Not a Receptor for Saturated Fatty Acids but Mediates Lipid-Induced Inflammation by Reprogramming Macrophage Metabolism Cell Metab., 2018-04-19;0(0):. 2018-04-19 [PMID: 29681442] (Mouse) |
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| M Bambouskov, L Gorvel, V Lampropoul, A Sergushich, E Loginichev, K Johnson, D Korenfeld, ME Mathyer, H Kim, LH Huang, D Duncan, H Bregman, A Keskin, A Santeford, RS Apte, R Sehgal, B Johnson, GK Amarasingh, MP Soares, T Satoh, S Akira, T Hai, C de Guzman, K Auclair, TP Roddy, SA Biller, M Jovanovic, E Klechevsky, KM Stewart, GJ Randolph, MN Artyomov Electrophilic properties of itaconate and derivatives regulate the�I?B?-ATF3 inflammatory axis Nature, 2018-04-18;556(7702):501-504. 2018-04-18 [PMID: 29670287] (Mouse) |
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| T Yoshimoto, T Hayashi, T Kondo, M Kittaka, EJ Reichenber, Y Ueki Second-generation SYK inhibitor entospletinib ameliorates fully established inflammation and bone destruction in the cherubism mouse model J. Bone Miner. Res., 2018-05-22;0(0):. 2018-05-22 [PMID: 29669173] (Mouse) |
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| MC Silva, M Davoli-Fer, TS Medina, R Sesti-Cost, GK Silva, CD Lopes, LE Cardozo, FN Gava, K Lyroni, FC Dias, AF Frade, M Baron, HI Nakaya, F Figueiredo, JC Alves-Filh, FQ Cunha, C Tsatsanis, C Chevillard, E Cunha-Neto, E Hirsch, JS Silva, TM Cunha Canonical PI3K? signaling in myeloid cells restricts Trypanosoma cruzi infection and dampens chagasic myocarditis Nat Commun, 2018-04-17;9(1):1513. 2018-04-17 [PMID: 29666415] (Mouse) |
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| F Mouton-Lig, T Rosazza, J Sepulveda-, A Ieang, SM Hassoun, E Claire, G Mangone, A Brice, PP Michel, JC Corvol, O Corti Parkin deficiency modulates NLRP3 inflammasome activation by attenuating an A20-dependent negative feedback loop Glia, 2018-04-17;0(0):. 2018-04-17 [PMID: 29665074] (Mouse) |
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| K Hirai, H Furusho, K Hirota, H Sasaki Activation of hypoxia-inducible factor�1 attenuates periapical inflammation and bone loss Int J Oral Sci, 2018-04-13;10(2):12. 2018-04-13 [PMID: 29654284] (Mouse) |
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| HT Wang, LC Yang, HC Yu, ML Chen, HJ Wang, TJ Lu Characteristics of fucose-containing polysaccharides from submerged fermentation of�Agaricus blazei Murill J Food Drug Anal, 2017-08-18;26(2):678-687. 2017-08-18 [PMID: 29567238] (Mouse) |
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| D Gr?evi?, M Sironi, S Valentino, L Deban, H Cvija, A Inforzato, N Kova?i?, V Katavi?, T Kelava, I Kalajzi?, A Mantovani, B Bottazzi The Long Pentraxin 3 Plays a Role in Bone Turnover and Repair Front Immunol, 2018-03-05;9(0):417. 2018-03-05 [PMID: 29556234] (Mouse) |
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| B Chang, B Koo, H Lee, JS Oh, S Kim Activation of macrophage mediated host defense againstSalmonella typhimuriumbyMorus albaL Food Nutr Res, 2018-02-21;62(0):. 2018-02-21 [PMID: 29545736] (Mouse) |
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| M Murase, T Kawasaki, R Hakozaki, T Sueyoshi, DDP Putri, Y Kitai, S Sato, M Ikawa, T Kawai Intravesicular Acidification Regulates Lipopolysaccharide Inflammation and Tolerance through TLR4 Trafficking J. Immunol., 2018-03-14;0(0):. 2018-03-14 [PMID: 29540576] (Mouse) |
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| SM Jung, J Lee, SY Baek, J Lee, SG Jang, SM Hong, JS Park, ML Cho, SH Park, SK Kwok Fraxinellone Attenuates Rheumatoid Inflammation in Mice Int J Mol Sci, 2018-03-13;19(3):. 2018-03-13 [PMID: 29533969] (Mouse) |
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| TM Finlay, AL Palmer, SS Ousman Murine neutrophils treated with alphaB-crystallin reduce IL-12p40 production by dendritic cells Immunology, 2018-04-17;0(0):. 2018-04-17 [PMID: 29532462] (Mouse) |
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| HL Lu, XY Huang, YF Luo, WP Tan, PF Chen, YB Guo Activation of M1 macrophages play a critical role in the initiation of acute lung injury Biosci. Rep., 2018-04-27;0(0):. 2018-04-27 [PMID: 29531017] (Mouse) |
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| A Carreras-G, N Navasa, I Martín-Rui, JL Lavín, M Azkargorta, E Atondo, D Barriales, N Macías-Cám, MA Pascual-It, L Sampedro, J Tomás-Cort, A Peña-Cearr, A Pellón, R Prados-Ros, L Abecia, F Elortza, AM Aransay, H Rodríguez, J Anguita A multi-omic analysis reveals the regulatory role of CD180 during the response of macrophages to Borrelia burgdorferi Emerg Microbes Infect, 2018-03-07;7(1):19. 2018-03-07 [PMID: 29511161] (Mouse) |
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| LB Martins, MC Oliveira, Z Menezes-Ga, DF Rodrigues, JP Lana, LQ Vieira, MM Teixeira, AVM Ferreira Paradoxical role of tumor necrosis factor on metabolic dysfunction and adipose tissue expansion in mice Nutrition, 2017-07-17;50(0):1-7. 2017-07-17 [PMID: 29510322] (Mouse) |
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| A Nemmar, S Al-Salam, S Beegam, P Yuvaraju, N Hamadi, BH Ali In Vivo Protective Effects of Nootkatone against Particles-Induced Lung Injury Caused by Diesel Exhaust Is Mediated via the NF-?B Pathway Nutrients, 2018-02-26;10(3):. 2018-02-26 [PMID: 29495362] (Mouse) |
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| MJ Park, SH Lee, EK Kim, EJ Lee, JA Baek, SH Park, SK Kwok, ML Cho Interleukin-10 produced by myeloid-derived suppressor cells is critical for the induction of Tregs and attenuation of rheumatoid inflammation in mice Sci Rep, 2018-02-28;8(1):3753. 2018-02-28 [PMID: 29491381] (Mouse) |
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| P Revathikum, J Estelius, U Karmakar, E Le Maître, M Korotkova, PJ Jakobsson, J Lampa Microsomal prostaglandin E synthase-1 gene deletion impairs neuro-immune circuitry of the cholinergic anti-inflammatory pathway in endotoxaemic mouse spleen PLoS ONE, 2018-02-22;13(2):e0193210. 2018-02-22 [PMID: 29470537] (Mouse) |
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| RG Carroll, Z Zas?ona, S Galván-Peñ, EL Koppe, DC Sévin, S Angiari, M Triantafil, K Triantafil, LK Modis, LA O'Neill An unexpected link between fatty acid synthase and cholesterol synthesis in proinflammatory macrophage activation J. Biol. Chem., 2018-02-20;293(15):5509-5521. 2018-02-20 [PMID: 29463677] (Mouse) |
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| M Yurchenko, A Skjesol, L Ryan, GM Richard, RK Kandasamy, N Wang, C Terhorst, H Husebye, T Espevik SLAMF1 is required for TLR4-mediated TRAM-TRIF-dependent signaling in human macrophages J. Cell Biol., 2018-02-12;0(0):. 2018-02-12 [PMID: 29440514] (Mouse) |
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| CFCG Nunes, JS Nogueira, FB Canto, PHO Vianna, BT Ciambarell, PMRE Silva, KR Miranda, LA Lobo, RMCP Domingues, M Busch, GC Atella, AM Vale, M Bellio, A Nóbrega, R Fucs Probiotic treatment during neonatal age provides optimal protection against experimental asthma through the modulation of microbiota and T cells: Neonatal exposure to probiotics prevents asthma Int. Immunol., 2018-04-03;0(0):. 2018-04-03 [PMID: 29420746] (ELISA Capture, Mouse) |
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| MJ Oh, HD Choi, SK Ha, I Choi, HY Park Immunomodulatory effects of polysaccharide fraction isolated from Fagopyrum esculentum on innate immune system Biochem. Biophys. Res. Commun., 2018-01-31;0(0):. 2018-01-31 [PMID: 29402410] (Mouse) |
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| ND Van Skike, NK Minkah, CH Hogan, G Wu, PT Benziger, DG Oldenburg, M Kara, DM Kim-Holzap, DW White, SA Tibbetts, JB French, LT Krug Viral FGARAT ORF75A promotes early events in lytic infection and gammaherpesvirus pathogenesis in mice PLoS Pathog., 2018-02-01;14(2):e1006843. 2018-02-01 [PMID: 29390024] (Mouse) |
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| A Kia, K McAvoy, K Krishnamur, D Trotti, P Pasinelli Astrocytes expressing ALS-linked mutant FUS induce motor neuron death through release of tumor necrosis factor-alpha Glia, 2018-01-30;0(0):. 2018-01-30 [PMID: 29380416] (Mouse) |
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Mouse |
| V Lamontain, T Schmid, D Weber-Stef, D Zeller, Z Jenei-Lanz, H Wajant, RH Straub, DN Männel Stimulation of TNF receptor type 2 expands regulatory T cells and ameliorates established collagen-induced arthritis in mice Cell. Mol. Immunol., 2018-01-29;0(0):. 2018-01-29 [PMID: 29375132] (Mouse) |
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| A Rutkowska, DR Shimshek, AW Sailer, KK Dev EBI2 regulates pro-inflammatory signalling and cytokine release in astrocytes Neuropharmacology, 2018-01-31;133(0):121-128. 2018-01-31 [PMID: 29374507] (Mouse) |
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| N Torika, K Asraf, RN Apte, S Fleisher-B Candesartan ameliorates brain inflammation associated with Alzheimer's disease CNS Neurosci Ther, 2018-01-24;0(0):. 2018-01-24 [PMID: 29365370] (Mouse, Rat) |
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Mouse, Rat |
| JB Herrmann, M Muensterma, L Strobel, A Schubert-U, TM Woodruff, SD Gray-Owen, A Klos, KO Johswich Complement C5a Receptor 1 Exacerbates the Pathophysiology of N.�meningitidis Sepsis and Is a Potential Target for Disease Treatment MBio, 2018-01-23;9(1):. 2018-01-23 [PMID: 29362231] (Mouse) |
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Mouse |
| HS Han, E Jang, JS Shin, KS Inn, JH Lee, G Park, YP Jang, KT Lee Kyungheechunggan-Tang-01, a New Herbal Medication, Suppresses LPS-Induced Inflammatory Responses through JAK/STAT Signaling Pathway in RAW 264.7 Macrophages Evid Based Complement Alternat Med, 2017-11-29;2017(0):7383104. 2017-11-29 [PMID: 29348772] (Mouse) |
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| SY Huang, SH Tai, CC Chang, YF Tu, CH Chang, EJ Lee Magnolol protects against ischemic-reperfusion brain damage following oxygen-glucose deprivation and transient focal cerebral ischemia Int. J. Mol. Med., 2018-01-15;0(0):. 2018-01-15 [PMID: 29336466] (Mouse) |
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| L Boutens, GJ Hooiveld, S Dhingra, RA Cramer, MG Netea, R Stienstra Unique metabolic activation of adipose tissue macrophages in obesity promotes inflammatory responses Diabetologia, 2018-01-14;0(0):. 2018-01-14 [PMID: 29333574] (Mouse) |
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| MS Gresnigt, M Jaeger, RK Subbarao M, O Rasid, G Jouvion, C Fitting, WJG Melchers, TD Kanneganti, A Carvalho, O Ibrahim-Gr, FL van de Vee The Absence of NOD1 Enhances Killing of Aspergillus fumigatus Through Modulation of Dectin-1 Expression Front Immunol, 2017-12-13;8(0):1777. 2017-12-13 [PMID: 29326692] (Mouse) |
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| FN Penas, D Carta, G Dmytrenko, GA Mirkin, CP Modenutti, ÁC Cevey, MJ Rada, MG Ferlin, ME Sales, NB Goren Treatment with a New Peroxisome Proliferator-Activated Receptor Gamma Agonist, Pyridinecarboxylic Acid Derivative, Increases Angiogenesis and Reduces Inflammatory Mediators in the Heart of Trypanosoma cruzi-Infected Mice Front Immunol, 2017-12-11;8(0):1738. 2017-12-11 [PMID: 29312293] (Mouse) |
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| S Paetau, T Rolova, L Ning, CG Gahmberg Neuronal ICAM-5 Inhibits Microglia Adhesion and Phagocytosis and Promotes an Anti-inflammatory Response in LPS Stimulated Microglia Front Mol Neurosci, 2017-12-22;10(0):431. 2017-12-22 [PMID: 29311819] (Mouse) |
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| AJ Smith, B Graves, R Child, PJ Rice, Z Ma, DW Lowman, HE Ensley, KT Ryter, JT Evans, DL Williams Immunoregulatory Activity of the Natural Product Laminarin Varies Widely as a Result of Its Physical Properties J. Immunol., 2017-12-15;0(0):. 2017-12-15 [PMID: 29246954] (Mouse) |
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Mouse |
| M Ivin, A Dumigan, FN de Vasconc, F Ebner, M Borroni, A Kavirayani, KN Przybyszew, RJ Ingram, S Lienenklau, U Kalinke, D Stoiber, JA Bengoechea, P Kovarik Natural killer cell-intrinsic type I IFN signaling controls Klebsiella pneumoniae growth during lung infection PLoS Pathog., 2017-11-07;13(11):e1006696. 2017-11-07 [PMID: 29112952] (Mouse) |
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Mouse |
| HH Lee, SG Lee, JS Shin, HY Lee, K Yoon, YW Ji, DS Jang, KT Lee p-Coumaroyl Anthocyanin Mixture Isolated from Tuber Epidermis of Solanum tuberosum Attenuates Reactive Oxygen Species and Pro-inflammatory Mediators by Suppressing NF-?B and STAT1/3 Signaling in LPS-Induced RAW264.7 Macrophages Biol. Pharm. Bull., 2017-01-01;40(11):1894-1902. 2017-01-01 [PMID: 29093336] (Mouse) |
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| A Singh, B Koduru, C Carlisle, H Akhter, RM Liu, K Schroder, RP Brandes, DM Ojcius NADPH oxidase 4 modulates hepatic responses to lipopolysaccharide mediated by Toll-like receptor-4 Sci Rep, 2017-10-30;7(1):14346. 2017-10-30 [PMID: 29085012] (Mouse) |
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| G Dunsmore, N Bozorgmehr, C Delyea, P Koleva, A Namdar, S Elahi Erythroid Suppressor Cells Compromise Neonatal Immune Response against Bordetella pertussis J. Immunol., 2017-08-04;0(0):. 2017-08-04 [PMID: 28779022] (Mouse) |
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| H Talwar, C Bauerfeld, Y Liu, L Samavati The dataset describes: HIF-1 ? expression and LPS mediated cytokine production in MKP-1 deficient bone marrow derived murine macrophages Data Brief, 2017-07-20;14(0):56-61. 2017-07-20 [PMID: 28765831] (Mouse) |
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| M Coorens, VAF Schneider, AM de Groot, A van Dijk, M Meijerink, JM Wells, MR Scheenstra, EJA Veldhuizen, HP Haagsman Cathelicidins Inhibit Escherichia coli-Induced TLR2 and TLR4 Activation in a Viability-Dependent Manner J. Immunol., 2017-07-14;0(0):. 2017-07-14 [PMID: 28710255] (Mouse) |
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| A Imai, K Satoi, E Fujimoto, K Sato Inducing maternal inflammation promotes leptin production in offspring but does not improve allergic symptoms in a mouse model of allergic rhinitis Heliyon, 2017-06-22;3(6):e00327. 2017-06-22 [PMID: 28707000] (Mouse) |
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Mouse |
| Y Rui, L Tong, J Cheng, G Wang, L Qin, Z Wan Rosmarinic acid suppresses adipogenesis, lipolysis in 3T3-L1 adipocytes, lipopolysaccharide-stimulated tumor necrosis factor-? secretion in macrophages, and inflammatory mediators in 3T3-L1 adipocytes Food Nutr Res, 2017-06-07;61(1):1330096. 2017-06-07 [PMID: 28659738] (Mouse) |
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Mouse |
| L Shmuel-Gal, Y Klug, Z Porat, M Charni, B Zarmi, Y Shai Intramembrane attenuation of the TLR4-TLR6 dimer impairs receptor assembly and reduces microglia mediated neurodegeneration J. Biol. Chem., 2017-06-27;0(0):. 2017-06-27 [PMID: 28655763] (Mouse) |
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Mouse |
| LN Masi, AR Martins, AR Crisma, CL do Amaral, MR Davanso, TDA Serdan, RDC da Cunha d, MM Cruz, MIC Alonso-Val, RP Torres, J Mancini-Fi, JNB Pereira, MM da Silva R, EA Liberti, SM Hirabara, R Curi Combination of a high-fat diet with sweetened condensed milk exacerbates inflammation and insulin resistance induced by each separately in mice Sci Rep, 2017-06-21;7(1):3937. 2017-06-21 [PMID: 28638152] (Mouse) |
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Mouse |
| Á Vinué, J Navarro, A Herrero-Ce, M García-Cub, I Andrés-Bla, S Martínez-H, JT Real, JF Ascaso, H González-N The GLP-1 analogue lixisenatide decreases atherosclerosis in insulin-resistant mice by modulating macrophage phenotype Diabetologia, 2017-06-12;0(0):. 2017-06-12 [PMID: 28608285] (Mouse) |
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Mouse |
| RF Espírito-S, CS Meira, RDS Costa, OP Souza Filh, AF Evangelist, GHG Trossini, GM Ferreira, EDS Velozo, CF Villarreal, MB Pereira So The anti-inflammatory and immunomodulatory potential of braylin: Pharmacological properties and mechanisms by in silico, in vitro and in vivo approaches PLoS ONE, 2017-06-08;12(6):e0179174. 2017-06-08 [PMID: 28594906] (Mouse) |
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| JM Orellana, K Kampe, F Schulze, J Sieber, AW Jehle Fetuin-A aggravates lipotoxicity in podocytes via interleukin-1 signaling Physiol Rep, 2017-05-01;5(10):. 2017-05-01 [PMID: 28554965] (Mouse) |
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Mouse |
| V Neudecker, M Haneklaus, O Jensen, L Khailova, JC Masterson, H Tye, K Biette, P Jedlicka, KS Brodsky, ME Gerich, M Mack, AAB Robertson, MA Cooper, GT Furuta, CA Dinarello, LA O'Neill, HK Eltzschig, SL Masters, EN McNamee Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome J. Exp. Med., 2017-05-09;0(0):. 2017-05-09 [PMID: 28487310] (Mouse) |
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Mouse |
| MC Souza, DM Fonseca, A Kanashiro, L Benevides, TS Medina, MS Dias, WA Andrade, G Bonfá, MAB Silva, A Gozzi, MC Borges, RT Gazzinelli, JC Alves-Filh, FQ Cunha, JS Silva Chronic Toxoplasma gondii Infection Exacerbates Secondary Polymicrobial Sepsis Front Cell Infect Microbiol, 2017-04-07;7(0):116. 2017-04-07 [PMID: 28439500] (Mouse) |
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Mouse |
| A Nemmar, S Al-Salam, S Beegam, P Yuvaraju, BH Ali The acute pulmonary and thrombotic effects of cerium oxide nanoparticles after intratracheal instillation in mice Int J Nanomedicine, 2017-04-10;12(0):2913-2922. 2017-04-10 [PMID: 28435267] (Mouse) |
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| S Kang, S Ahn, J Lee, JY Kim, M Choi, V Gujrati, H Kim, J Kim, EC Shin, S Jon Effects of gold nanoparticle-based vaccine size on lymph node delivery and cytotoxic T-lymphocyte responses J Control Release, 2017-04-18;256(0):56-67. 2017-04-18 [PMID: 28428066] (Mouse) |
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| PC Chen, MH Hsieh, P Wen-ShuoKu, HF Kao, CL Hsu, JY Wang Water-soluble chitosan inhibits nerve growth factor and attenuates allergic inflammation in mite allergen-induced allergic rhinitis J. Allergy Clin. Immunol., 2017-04-12;0(0):. 2017-04-12 [PMID: 28412394] (Mouse) |
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Mouse |
| CT Molloy, JS Andonian, HM Seltzer, MC Procario, ME Watson, JB Weinberg Contributions of CD8 T cells to the pathogenesis of mouse adenovirus type 1 respiratory infection Virology, 2017-04-11;507(0):64-74. 2017-04-11 [PMID: 28410483] (Mouse) |
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Mouse |
| A Nemmar, P Yuvaraju, S Beegam, MA Fahim, BH Ali Cerium Oxide Nanoparticles in Lung Acutely Induce Oxidative Stress, Inflammation, and DNA Damage in Various Organs of Mice Oxid Med Cell Longev, 2017-03-14;2017(0):9639035. 2017-03-14 [PMID: 28392888] (Mouse) |
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Mouse |
| TM Tu, BJ Kolls, EJ Soderblom, V Cantillana, PD Ferrell, MA Moseley, H Wang, HN Dawson, DT Laskowitz Apolipoprotein E mimetic peptide, CN-105, improves outcomes in ischemic stroke Ann Clin Transl Neurol, 2017-03-09;4(4):246-265. 2017-03-09 [PMID: 28382306] (Mouse) |
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| JP Barrett, RJ Henry, S Villapol, BA Stoica, A Kumar, MP Burns, AI Faden, DJ Loane NOX2 deficiency alters macrophage phenotype through an IL-10/STAT3 dependent mechanism: implications for traumatic brain injury J Neuroinflammation, 2017-03-24;14(1):65. 2017-03-24 [PMID: 28340575] (Mouse) |
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| M Lynch, TA Walsh, I Marszalows, AE Webb, M MacAogain, TR Rogers, H Windle, D Kelleher, MJ O'Connell, CE Loscher Surface layer proteins from virulent Clostridium difficile ribotypes exhibit signatures of positive selection with consequences for innate immune response BMC Evol. Biol, 2017-03-23;17(1):90. 2017-03-23 [PMID: 28335725] (Mouse) |
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Mouse |
| LL Ventura, NC Fortes, HC Santiago, MV Caliari, MA Gomes, DR Oliveira Obesity-induced diet leads to weight gain, systemic metabolic alterations, adipose tissue inflammation, hepatic steatosis, and oxidative stress in gerbils (Meriones unguiculatus) PeerJ, 2017-03-02;5(0):e2967. 2017-03-02 [PMID: 28265495] (Gerbil) |
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Gerbil |
| A Nemmar, S Al-Salam, S Beegam, P Yuvaraju, A Oulhaj, BH Ali Water-Pipe Smoke Exposure-Induced Circulatory Disturbances in Mice, and the Influence of Betaine Supplementation Thereon Cell. Physiol. Biochem, 2017-02-27;41(3):1098-1112. 2017-02-27 [PMID: 28245471] (Mouse) |
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Mouse |
| M Koppenol-R, VH Sjoelund, NP Manes, RA Gottschalk, B Dutta, ZL Benet, ID Fraser, A Nita-Lazar Proteome and secretome analysis reveals differential post-transcriptional regulation of Toll-like receptor responses Mol. Cell Proteomics, 2017-02-24;0(0):. 2017-02-24 [PMID: 28235783] (Mouse) |
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| PB McElroy, A Sri Hari, BJ Day, M Patel Post-translational Activation of Glutamate Cysteine Ligase with Dimercaprol: A Novel Mechanism of Inhibiting Neuroinflammation in vitro J. Biol. Chem, 2017-02-15;0(0):. 2017-02-15 [PMID: 28202547] (Mouse) |
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| M Coorens, MR Scheenstra, EJ Veldhuizen, HP Haagsman Interspecies cathelicidin comparison reveals divergence in antimicrobial activity, TLR modulation, chemokine induction and regulation of phagocytosis Sci Rep, 2017-01-19;7(0):40874. 2017-01-19 [PMID: 28102367] (Mouse) |
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| CF Chang, KC Liao, CH Chen 2-Phenylnaphthalene Derivatives Inhibit Lipopolysaccharide-Induced Pro-Inflammatory Mediators by Downregulating of MAPK/NF-?B Pathways in RAW 264.7 Macrophage Cells PLoS ONE, 2017-01-06;12(1):e0168945. 2017-01-06 [PMID: 28060845] (Mouse) |
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| Flavia Regina Sobreira Corrêa Brazilian red propolis improves cutaneous wound healing suppressing inflammation-associated transcription factor NF?B Biomed. Pharmacother, 2016-12-12;86(0):162-171. 2016-12-12 [PMID: 27978495] (Mouse) |
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| Miguel Del Campo Sublethal doses of Dinophysistoxin-1 and Okadaic acid stimulate secretion of inflammatory factors on innate immune cells: Negative health consequences Toxicon, 2016-12-09;0(0):. 2016-12-09 [PMID: 27956244] (Mouse) |
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| Rujin Huang Indoor secondary organic aerosols formation from ozonolysis of monoterpene: An example of d-limonene with ammonia and potential impacts on pulmonary inflammations Sci. Total Environ., 2016-11-11;0(0):. 2016-11-11 [PMID: 27842959] (Mouse) |
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| Jand Venes R Medeiros Carvacrol reduces irinotecan-induced intestinal mucositis through inhibition of inflammation and oxidative damage via TRPA1 receptor activation Chem. Biol. Interact., 2016-11-09;260(0):129-140. 2016-11-09 [PMID: 27838229] (Mouse) |
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| Microbiota-inducible Innate Immune, Siderophore Binding Protein Lipocalin 2 is Critical for Intestinal Homeostasis Cell Mol Gastroenterol Hepatol, 2016-07-01;2(4):482-498.e6. 2016-07-01 [PMID: 27458605] (Mouse) |
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| Eun-Jeong Yoon Contribution of the Ade Resistance-Nodulation-Cell Division-Type Efflux Pumps to Fitness and Pathogenesis of Acinetobacter baumannii MBio, 2016-05-31;7(3):. 2016-05-31 [PMID: 27247231] (Mouse) |
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| Neutrophil Attack Triggers Extracellular Trap-Dependent Candida Cell Wall Remodeling and Altered Immune Recognition PLoS Pathog, 2016-05-25;12(5):e1005644. 2016-05-25 [PMID: 27223610] (Mouse) |
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| Hemocyanins Stimulate Innate Immunity by Inducing Different Temporal Patterns of Proinflammatory Cytokine Expression in Macrophages J Immunol, 2016-04-22;196(11):4650-62. 2016-04-22 [PMID: 27183578] (Mouse) |
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| Immune Cell-Conditioned Media Suppress Prostate Cancer PC-3 Cell Growth Correlating With Decreased Proinflammatory/Anti-inflammatory Cytokine Ratios in the Media Using 5 Selected Crude Polysaccharides Integr Cancer Ther, 2016-04-29;15(4):NP13-NP25. 2016-04-29 [PMID: 27130724] (Mouse) |
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| A Savers, O Rasid, M Parlato, M Brock, G Jouvion, B Ryffel, JM Cavaillon, G Eberl, O Ibrahim-Gr Infection-Mediated Priming of Phagocytes Protects against Lethal Secondary Aspergillus fumigatus Challenge PLoS ONE, 2016-04-14;11(4):e0153829. 2016-04-14 [PMID: 27078879] (Mouse) |
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| Keranen T, Hommo T, Hamalainen M, Moilanen E, Korhonen R Anti-Inflammatory Effects of beta2-Receptor Agonists Salbutamol and Terbutaline Are Mediated by MKP-1. PLoS ONE, 2016-02-05;11(2):e0148144. 2016-02-05 [PMID: 26849227] (Mouse) |
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| Shah D, Romero F, Zhu Y, Duong M, Sun J, Walsh K, Summer R C1q Deficiency Promotes Pulmonary Vascular Inflammation and Enhances the Susceptibility of the Lung Endothelium to Injury. J Biol Chem, 2015-10-20;290(49):29642-51. 2015-10-20 [PMID: 26487714] (Mouse) |
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| Petnicki-Ocwieja T, Kern A, Killpack T, Bunnell S, Hu L Adaptor Protein-3-Mediated Trafficking of TLR2 Ligands Controls Specificity of Inflammatory Responses but Not Adaptor Complex Assembly. J Immunol, 2015-09-30;195(9):4331-40. 2015-09-30 [PMID: 26423153] (Mouse) |
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| Wang H, Sethi G, Loke W, Sim M Des-Aspartate-Angiotensin I Attenuates Mortality of Mice Exposed to Gamma Radiation via a Novel Mechanism of Action. PLoS ONE, 2015-09-17;10(9):e0138009. 2015-09-17 [PMID: 26378927] (Mouse) |
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| Avila L, Bruggemann T, Bobinski F, da Silva M, Oliveira R, Martins D, Mazzardo-Martins L, Duarte M, de Souza L, Dafre A, Vieira R, Santos A, Bonorino K, Hizume Kunzler D Effects of High-Intensity Swimming on Lung Inflammation and Oxidative Stress in a Murine Model of DEP-Induced Injury. PLoS ONE, 2015-09-02;10(9):e0137273. 2015-09-02 [PMID: 26332044] (Mouse) |
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| Yoshida K, Maekawa T, Zhu Y, Renard-Guillet C, Chatton B, Inoue K, Uchiyama T, Ishibashi K, Yamada T, Ohno N, Shirahige K, Okada-Hatakeyama M, Ishii S The transcription factor ATF7 mediates lipopolysaccharide-induced epigenetic changes in macrophages involved in innate immunological memory. Nat Immunol, 2015-08-31;16(10):1034-43. 2015-08-31 [PMID: 26322480] (Mouse) |
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| Wu Y, Wu Y, Mo S, Hsiao H, He Y, Lai M Cellular FLIP Inhibits Myeloid Cell Activation by Suppressing Selective Innate Signaling. J Immunol, 2015-08-03;195(6):2612-23. 2015-08-03 [PMID: 26238491] (Mouse) |
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| Douglas T, Champagne C, Morizot A, Lapointe J, Saleh M The Inflammatory Caspases-1 and -11 Mediate the Pathogenesis of Dermatitis in Sharpin-Deficient Mice. J Immunol, 2015-07-27;195(5):2365-73. 2015-07-27 [PMID: 26216893] (Mouse) |
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| Saulep-Easton D, Vincent F, Quah P, Wei A, Ting S, Croce C, Tam C, Mackay F The BAFF receptor TACI controls IL-10 production by regulatory B cells and CLL B cells. Leukemia, 2015-07-03;30(1):163-72. 2015-07-03 [PMID: 26139429] (Mouse) |
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| Kortman G, Mulder M, Richters T, Shanmugam N, Trebicka E, Boekhorst J, Timmerman H, Roelofs R, Wiegerinck E, Laarakkers C, Swinkels D, Bolhuis A, Cherayil B, Tjalsma H Low dietary iron intake restrains the intestinal inflammatory response and pathology of enteric infection by food-borne bacterial pathogens. Eur J Immunol, 2015-06-23;45(9):2553-67. 2015-06-23 [PMID: 26046550] (Mouse) |
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| Tan Z, Xie N, Cui H, Moellering D, Abraham E, Thannickal V, Liu G Pyruvate dehydrogenase kinase 1 participates in macrophage polarization via regulating glucose metabolism. J Immunol, 2015-05-11;194(12):6082-9. 2015-05-11 [PMID: 25964487] (Mouse) |
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| Alissafi T, Hatzioannou A, Ioannou M, Sparwasser T, Grun J, Grutzkau A, Verginis P De novo-induced self-antigen-specific Foxp3+ regulatory T cells impair the accumulation of inflammatory dendritic cells in draining lymph nodes. J Immunol, 2015-05-06;194(12):5812-24. 2015-05-06 [PMID: 25948818] (Mouse) |
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| Todd D, Gulledge T, Britton E, Oberhofer M, Leyte-Lugo M, Moody A, Shymanovich T, Grubbs L, Juzumaite M, Graf T, Oberlies N, Faeth S, Laster S, Cech N Ethanolic Echinacea purpurea Extracts Contain a Mixture of Cytokine-Suppressive and Cytokine-Inducing Compounds, Including Some That Originate from Endophytic Bacteria. PLoS ONE, 2015-05-01;10(5):e0124276. 2015-05-01 [PMID: 25933416] (Mouse) |
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| Maruhashi T, Kaifu T, Yabe R, Seno A, Chung S, Fujikado N, Iwakura Y DCIR maintains bone homeostasis by regulating IFN-gamma production in T cells. J Immunol, 2015-04-29;194(12):5681-91. 2015-04-29 [PMID: 25926676] (Mouse) |
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| Secor McVoy J, Oughli H, Oh U Liver X receptor-dependent inhibition of microglial nitric oxide synthase 2. J Neuroinflammation, 2015-02-10;12(0):27. 2015-02-10 [PMID: 25889344] (Mouse) |
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| Gillgrass A, Chew M, Krneta T, Ashkar A Overexpression of IL-15 promotes tumor destruction via NK1.1+ cells in a spontaneous breast cancer model. BMC Cancer, 2015-04-16;15(0):293. 2015-04-16 [PMID: 25879689] (Mouse) |
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| Kim S, Joe Y, Kim H, Kim Y, Jeong S, Pae H, Ryter S, Surh Y, Chung H Endoplasmic reticulum stress-induced IRE1alpha activation mediates cross-talk of GSK-3beta and XBP-1 to regulate inflammatory cytokine production. J Immunol, 2015-03-27;194(9):4498-506. 2015-03-27 [PMID: 25821218] (Mouse) |
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| Yang L, Brooks C, Xiao S, Sabbisetti V, Yeung M, Hsiao L, Ichimura T, Kuchroo V, Bonventre J KIM-1-mediated phagocytosis reduces acute injury to the kidney. J Clin Invest, 2015-03-09;125(4):1620-36. 2015-03-09 [PMID: 25751064] (Mouse) |
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| Na Y, Yoon Y, Son D, Jung D, Gu G, Seok S Consistent inhibition of cyclooxygenase drives macrophages towards the inflammatory phenotype. PLoS ONE, 2015-02-13;10(2):e0118203. 2015-02-13 [PMID: 25680189] (Mouse) |
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| Kim J, Sohn J, Lee J, Park J Obesity increases airway hyperresponsiveness via the TNF-alpha pathway and treating obesity induces recovery. PLoS ONE, 2015-02-06;10(2):e0116540. 2015-02-06 [PMID: 25658739] (Mouse) |
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| Herbst S, Shah A, Mazon Moya M, Marzola V, Jensen B, Reed A, Birrell M, Saijo S, Mostowy S, Shaunak S, Armstrong-James D Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus. EMBO Mol Med, 2015-03-01;7(3):240-58. 2015-03-01 [PMID: 25637383] (Mouse) |
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| Ma C, Chang W, Shi G, Chang B, Cheng S, Shih Y, Wu H Recombinant thrombomodulin inhibits lipopolysaccharide-induced inflammatory response by blocking the functions of CD14. J Immunol, 2015-01-21;194(4):1905-15. 2015-01-21 [PMID: 25609841] (Mouse) |
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| Li Y, Chen H, Bannick N, Henry M, Holm A, Metwali A, Urban J, Rothman P, Weiner G, Blazar B, Elliott D, Ince M Intestinal helminths regulate lethal acute graft-versus-host disease and preserve the graft-versus-tumor effect in mice. J Immunol, 2014-12-19;194(3):1011-20. 2014-12-19 [PMID: 25527786] (Mouse) |
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| Barra , Nicole G, Palanivel , Rengasam, Denou , Emmanuel, Chew , Marianne, Gillgrass , Amy, Walker , Tina D, Kong , Josh, Richards , Carl D, Jordana , Manel, Collins , Stephen, Trigatti , Bernardo, Holloway , Alison C, Raha , Sandeep, Steinberg , Gregory, Ashkar , Ali A Interleukin-15 modulates adipose tissue by altering mitochondrial mass and activity. PLoS ONE, 2014-12-17;9(12):e114799. 2014-12-17 [PMID: 25517731] (Mouse) |
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| Bernard N, Finlay C, Tannahill G, Cassidy J, O'Neill L, Mills K A critical role for the TLR signaling adapter Mal in alveolar macrophage-mediated protection against Bordetella pertussis. Mucosal Immunol, 2014-12-17;8(5):982-92. 2014-12-17 [PMID: 25515629] (Mouse) |
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| Role of IL-1β in experimental cystic fibrosis upon P. aeruginosa infection. PLoS ONE, 2014-12-12;9(12):e114884. 2014-12-12 [PMID: 25500839] (Mouse) |
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| Clatworthy M, Harford S, Mathews R, Smith K FcgammaRIIb inhibits immune complex-induced VEGF-A production and intranodal lymphangiogenesis. Proc Natl Acad Sci U S A, 2014-12-04;111(50):17971-6. 2014-12-04 [PMID: 25475856] (Mouse) |
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| Vasanthan T, Rochow N, Mian F, Codini T, DeFrance B, Fusch G, Samiee-Zafarghandy S, Fusch C LPS from bovine serum albumin drives TNF-alpha release during ex-vivo placenta perfusion experiments, contaminates the perfusion system but can be effectively removed by oxidative cleaning. Placenta, 2014-10-18;35(12):1095-8. 2014-10-18 [PMID: 25454474] (Mouse) |
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| Lei B, Mace B, Dawson H, Warner D, Laskowitz D, James M Anti-inflammatory effects of progesterone in lipopolysaccharide-stimulated BV-2 microglia. PLoS ONE, 2014-07-31;9(7):e103969. 2014-07-31 [PMID: 25080336] (Mouse) |
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| Machado GB, de Oliveira AV, Saliba AM, de Lima CD, Suassuna JH, Plotkowski MC Pseudomonas aeruginosa toxin ExoU induces a PAF-dependent impairment of alveolar fibrin turnover secondary to enhanced activation of coagulation and increased expression of plasminogen activator inhibitor-1 in the course of mice pneumosepsis. Respir. Res., 2011-08-05;12(0):104. 2011-08-05 [PMID: 21819560] (Mouse) |
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| Nicholls HT, Kowalski G, Kennedy DJ Hematopoietic cell-restricted deletion of CD36 reduces high-fat diet-induced macrophage infiltration and improves insulin signaling in adipose tissue. Diabetes, 2011-03-04;60(4):1100-10. 2011-03-04 [PMID: 21378177] (Mouse) |
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| Graham BS, Kines RC, Corbett KS, Nicewonger J, Roberts JN, Schiller JT, Buck CB Mucosal delivery of human papillomavirus pseudovirus-encapsidated plasmids improves the potency of DNA vaccination. Mucosal Immunol, 2010-06-16;3(5):475-86. 2010-06-16 [PMID: 20555315] (Mouse) |
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| Li Z, Alam S, Wang J, Sandstrom CS, Janciauskiene S, Mahadeva R Oxidized alpha1-antitrypsin stimulates the release of monocyte chemotactic protein-1 from lung epithelial cells: potential role in emphysema. Am. J. Physiol. Lung Cell Mol. Physiol., 2009-06-12;297(2):L388-400. 2009-06-12 [PMID: 19525388] (Mouse) |
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| Souza DG, Amaral FA, Fagundes CT, Coelho FM, Arantes RM, Sousa LP, Matzuk MM, Garlanda C, Mantovani A, Dias AA, Teixeira MM The long pentraxin PTX3 is crucial for tissue inflammation after intestinal ischemia and reperfusion in mice. Am. J. Pathol., 2009-03-12;174(4):1309-18. 2009-03-12 [PMID: 19286566] (Mouse) |
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| Darniot M, Pitoiset C, Petrella T, Aho S, Pothier P, Manoha C Age-associated aggravation of clinical disease after primary metapneumovirus infection of BALB/c mice. J. Virol., 2009-01-14;83(7):3323-32. 2009-01-14 [PMID: 19144706] (Mouse) |
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| Kaya Z, Goser S, Buss SJ, Leuschner F, Ottl R, Li J, Volkers M, Zittrich S, Pfitzer G, Rose NR, Katus HA Identification of cardiac troponin I sequence motifs leading to heart failure by induction of myocardial inflammation and fibrosis. Circulation, 2008-10-27;118(20):2063-72. 2008-10-27 [PMID: 18955666] (Mouse) |
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| Wang S, Wu D, Matthan NR, Lamon-Fava S, Lecker JL, Lichtenstein AH Reduction in dietary omega-6 polyunsaturated fatty acids: eicosapentaenoic acid plus docosahexaenoic acid ratio minimizes atherosclerotic lesion formation and inflammatory response in the LDL receptor null mouse. Atherosclerosis, 2008-09-02;204(1):147-55. 2008-09-02 [PMID: 18842266] (Mouse) |
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| Miyazaki Y, Shimanoe Y, Wang S, Yoshida H Amelioration of delayed-type hypersensitivity responses by IL-27 administration. Biochem. Biophys. Res. Commun., 2008-06-20;373(3):397-402. 2008-06-20 [PMID: 18572017] (Mouse) |
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| Gaupp S, Cannella B, Raine CS Amelioration of experimental autoimmune encephalomyelitis in IL-4Ralpha-/- mice implicates compensatory up-regulation of Th2-type cytokines. Am. J. Pathol., 2008-06-05;173(1):119-29. 2008-06-05 [PMID: 18535177] (Mouse) |
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| Wan S, Zhou Z, Duan B, Morel L Direct B cell stimulation by dendritic cells in a mouse model of lupus. Arthritis Rheum., 2008-06-01;8(0):1741-50. 2008-06-01 [PMID: 18512810] (Mouse) |
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| Lembo A, Pelletier M, Iyer R, Timko M, Dudda JC, West TE, Wilson CB, Hajjar AM, Skerrett SJ Administration of a synthetic TLR4 agonist protects mice from pneumonic tularemia. J. Immunol., 2008-06-01;180(11):7574-81. 2008-06-01 [PMID: 18490759] (Mouse) |
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| Brandt EB, Mingler MK, Stevenson MD, Wang N, Khurana Hershey GK, Whitsett JA, Rothenberg ME Surfactant protein D alters allergic lung responses in mice and human subjects. J. Allergy Clin. Immunol., 2008-03-19;121(5):1140-1147.e2. 2008-03-19 [PMID: 18355911] (Mouse) |
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| Tiwari N, Wang CC, Brochetta C, Ke G, Vita F, Qi Z, Rivera J, Soranzo MR, Zabucchi G, Hong W, Blank U VAMP-8 segregates mast cell-preformed mediator exocytosis from cytokine trafficking pathways. Blood, 2008-01-18;111(7):3665-74. 2008-01-18 [PMID: 18203950] (Mouse) |
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| Doz E, Noulin N, Boichot E, Guenon I, Fick L, Le Bert M, Lagente V, Ryffel B, Schnyder B, Quesniaux VF, Couillin I Cigarette smoke-induced pulmonary inflammation is TLR4/MyD88 and IL-1R1/MyD88 signaling dependent. J. Immunol., 2008-01-15;180(2):1169-78. 2008-01-15 [PMID: 18178857] (Mouse) |
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| Macedo GC, Magnani DM, Carvalho NB, Bruna-Romero O, Gazzinelli RT, Oliveira SC Central role of MyD88-dependent dendritic cell maturation and proinflammatory cytokine production to control Brucella abortus infection. J. Immunol., 2008-01-15;180(2):1080-7. 2008-01-15 [PMID: 18178848] (Mouse) |
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| Obregon D, Hou H, Bai Y, Nikolic WV, Mori T, Luo D, Zeng J, Ehrhart J, Fernandez F, Morgan D, Giunta B, Town T, Tan J CD40L disruption enhances Abeta vaccine-mediated reduction of cerebral amyloidosis while minimizing cerebral amyloid angiopathy and inflammation. Neurobiol. Dis., 2007-10-16;29(2):336-53. 2007-10-16 [PMID: 18055209] (Mouse) |
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| Matalka KZ, Ali D, Khawad AE, Qa'dan F The differential effect of Eriobotrya japonica hydrophilic leaf extract on cytokines production and modulation. Cytokine, 2007-11-26;40(3):235-40. 2007-11-26 [PMID: 18036829] (Mouse) |
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| Cheng W, Shivshankar P, Li Z, Chen L, Yeh IT, Zhong G Caspase-1 contributes to Chlamydia trachomatis-induced upper urogenital tract inflammatory pathologies without affecting the course of infection. Infect. Immun., 2007-11-19;76(2):515-22. 2007-11-19 [PMID: 18025098] (Mouse) |
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| Natarajan A, Wagner B, Sibilia M The EGF receptor is required for efficient liver regeneration. Proc. Natl. Acad. Sci. U.S.A., 2007-10-16;104(43):17081-6. 2007-10-16 [PMID: 17940036] (Mouse) |
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| Jenkins SJ, Perona-Wright G, Worsley AG, Ishii N, MacDonald AS Dendritic cell expression of OX40 ligand acts as a costimulatory, not polarizing, signal for optimal Th2 priming and memory induction in vivo. J. Immunol., 2007-09-15;179(6):3515-23. 2007-09-15 [PMID: 17785785] (Mouse) |
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| Hwang SA, Wilk KM, Budnicka M, Olsen M, Bangale YA, Hunter RL, Kruzel ML, Actor JK Lactoferrin enhanced efficacy of the BCG vaccine to generate host protective responses against challenge with virulent Mycobacterium tuberculosis. Vaccine, 2007-07-27;25(37):6730-43. 2007-07-27 [PMID: 17698261] (Mouse) |
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| Schell JB, Crane CA, Smith MF, Roberts MR Differential ex vivo nitric oxide production by acutely isolated neonatal and adult microglia. J. Neuroimmunol., 2007-08-15;189(1):75-87. 2007-08-15 [PMID: 17698208] (Mouse) |
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| Hung LC, Lin CC, Hung SK, Wu BC, Jan MD, Liou SH, Fu SL A synthetic analog of alpha-galactosylceramide induces macrophage activation via the TLR4-signaling pathways. Biochem. Pharmacol., 2007-03-12;73(12):1957-70. 2007-03-12 [PMID: 17445776] (Mouse) |
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| Zamboni DS, Campos MA, Torrecilhas AC, Kiss K, Samuel JE, Golenbock DT, Lauw FN, Roy CR, Almeida IC, Gazzinelli RT Stimulation of toll-like receptor 2 by Coxiella burnetii is required for macrophage production of pro-inflammatory cytokines and resistance to infection. J. Biol. Chem., 2004-10-13;279(52):54405-15. 2004-10-13 [PMID: 15485838] (Mouse) |
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Mouse |
| Yarovinsky TO, Powers LS, Butler NS, Bradford MA, Monick MM, Hunninghake GW Adenoviral infection decreases mortality from lipopolysaccharide-induced liver failure via induction of TNF-alpha tolerance. J. Immunol., 2003-09-01;171(5):2453-60. 2003-09-01 [PMID: 12928393] (Mouse) |
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Mouse |
| Gilleron M, Quesniaux VF, Puzo G Acylation state of the phosphatidylinositol hexamannosides from Mycobacterium bovis bacillus Calmette Guerin and mycobacterium tuberculosis H37Rv and its implication in Toll-like receptor response. J. Biol. Chem., 2003-05-29;278(32):29880-9. 2003-05-29 [PMID: 12775723] (Mouse) |
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Mouse |
| van der Kleij D, Latz E, Brouwers JF, Kruize YC, Schmitz M, Kurt-Jones EA, Espevik T, de Jong EC, Kapsenberg ML, Golenbock DT, Tielens AG, Yazdanbakhsh M A novel host-parasite lipid cross-talk. Schistosomal lyso-phosphatidylserine activates toll-like receptor 2 and affects immune polarization. J. Biol. Chem., 2002-09-30;277(50):48122-9. 2002-09-30 [PMID: 12359728] (Mouse) |
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Mouse |
| O'Keeffe M CpG-DNA aided cross-presentation of soluble antigens by dendritic cells. Eur. J. Immunol., 2002-08-01;32(8):2356-64. 2002-08-01 [PMID: 12209649] (Mouse) |
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Mouse |
| O'Garra A Reversal of tumor-induced dendritic cell paralysis by CpG immunostimulatory oligonucleotide and anti-interleukin 10 receptor antibody. J. Exp. Med., 2002-08-19;196(4):541-9. 2002-08-19 [PMID: 12186845] (Mouse) |
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Mouse |
| Alexopoulou , L, Holt , A C, Medzhitov , R, Flavell , R A Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Nature, 2001-10-18;413(6857):732-8. 2001-10-18 [PMID: 11607032] (Mouse) |
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Mouse |
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Show All 746 Publications.
Collapse Publications.
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![N/A IL-6 [HRP]](https://images.novusbio.com/images2/IL-6_M6000_ELISA_415.jpg)
![N/A IL-6 [HRP]](https://images.novusbio.com/images/m6000b_mouse-il-6-quantikine-elisa-kit-44202415433118.jpg)
![N/A IL-10 [Biotin]](https://images.novusbio.com/images2/DATA_IL10_DY417_ELISA_2014.jpg)
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![SDS-PAGE IL-1 beta/IL-1F2 [Unconjugated]](https://images.novusbio.com/images2/IL-1_beta_201-LB_304.jpg)
![Bioactivity IL-1 beta/IL-1F2 [Unconjugated]](https://images.novusbio.com/images2/IL-1_beta_201-LB_306.jpg)
![SEC-MALS IL-1 beta/IL-1F2 [Unconjugated]](https://images.novusbio.com/images/201-lb_recombinant-human-il-1-beta-il-1f2-protein-sec-mals-123202491556.jpg)
![Bioactivity IL-2 [Unconjugated]](https://images.novusbio.com/images/202-il_recombinant-human-il-2-protein-bioactivity-174202314946.jpg)
![Bioactivity IL-4 [Unconjugated]](https://images.novusbio.com/images/protein/6507-ilcf_recombinant-human-il-4-cho-expressed-protein-cf-bioactivity-272020133214.jpg)
![Bioactivity CTLA-4 [Unconjugated]](https://images.novusbio.com/images2/CTLA4_7268CT_2293.jpg)
![N/A C-Reactive Protein/CRP [Biotin]](https://images.novusbio.com/images2/DATA_CReactive_Protein_DY1707_ELISA_1701.jpg)
![N/A CCL2/JE/MCP-1 [HRP]](https://images.novusbio.com/images2/CCL2_DCP00_ELISA_67.jpg)
![N/A CCL2/JE/MCP-1 [HRP]](https://images.novusbio.com/images2/DATA_CCL2_DCP00_ELISA_633.jpg)
![N/A CCL2/JE/MCP-1 [HRP]](https://images.novusbio.com/images2/DATA_CCL2_DCP00_ELISA_634.jpg)
![SDS-PAGE Lymphotoxin-alpha/TNF-beta [Unconjugated]](https://images.novusbio.com/images2/Lymphotoxin-alpha_211-TBB_CF_695.jpg)
![Bioactivity Lymphotoxin-alpha/TNF-beta [Unconjugated]](https://images.novusbio.com/images2/Lymphotoxin-alpha_211-TBB_CF_697.jpg)
![N/A TNF RI/TNFRSF1A [HRP]](https://images.novusbio.com/images2/DATA_TNF_RI_DRT100_ELISA_815.jpg)
![N/A TNF RI/TNFRSF1A [HRP]](https://images.novusbio.com/images2/DATA_TNF_RI_DRT100_ELISA_816.jpg)
![N/A TNF RI/TNFRSF1A [HRP]](https://images.novusbio.com/images2/TNF_RI_DRT100_ELISA_175.jpg)
![Western Blot ERK2 Antibody [Unconjugated]](https://images.novusbio.com/images2/ERK2_AF1230_Western_Blot_5097.jpg)
![Immunohistochemistry ERK2 Antibody [Unconjugated]](https://images.novusbio.com/images2/ERK2_AF1230_Immunohistochemistry_20696.jpg)
![Knockout Validated ERK2 Antibody [Unconjugated]](https://images.novusbio.com/images2/ERK2_AF1230_Knockout_Validated_22864.jpg)
