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Mouse GM-CSF Quantikine ELISA Kit, 2 Plate

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Summary
Reactivity MuSpecies Glossary
Applications ELISA
Conjugate
HRP

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Mouse GM-CSF Quantikine ELISA Kit, 2 Plate Summary

Background
The Quantikine Mouse GM-CSF Immunoassay is a 4.5 hour solid phase ELISA designed to measure mouse GM-CSF in cell culture supernates and serum. It contains E. coli-expressed recombinant mouse GM-CSF and antibodies raised against the recombinant factor. This immunoassay has been shown to quantitate the recombinant mouse GM-CSF accurately. Results obtained using natural mouse GM-CSF sh...owed dose-response curves that were parallel to the standard curves obtained using the recombinant standards. These results indicate that this kit can be used to determine relative mass values for natural mouse GM-CSF.
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Specificity
Natural and recombinant mouse GM-CSF
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
Csf2

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using MGM00.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse GM-CSF Quantikine ELISA Kit, 2 Plate

  • colony stimulating factor 2 (granulocyte-macrophage)
  • Colony-stimulating factor
  • CSF
  • CSF2
  • CSF-2
  • GMCSF
  • GM-CSF
  • GMCSFgranulocyte-macrophage colony-stimulating factor
  • granulocyte-macrophage colony stimulating factor
  • MGC131935
  • MGC138897
  • Molgramostim
  • molgramostin
  • Sargramostim

Background

GM-CSF (Granulocyte-Macrophage Colony Stimulating Factor) induces the development of monocytes, neutrophils, eosinophils, and myeloid and dermal dendritic cells. It also acts as a neutrophil and dendritic cell chemoattractant. GM-CSF promotes Th1 and Th17 cell mediated autoimmune inflammation as well as the inflammatory activation of dendritic cells, microglia, alveolar macrophages, and eosinophils. In addition, it cooperates with G-CSF in promoting tumor cell proliferation and invasion. GM-CSF signals through a receptor complex composed of GM-CSF R alpha and the Common beta Chain (beta c) with Syndecan-2 as a potential co-receptor. The beta c subunit is shared by the receptor complexes for IL-3 and IL-5.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for GM-CSF (MGM00)(36)

We have publications tested in 1 confirmed species: Mouse.


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Mouse
(35)
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Showing Publications 1 - 10 of 36. Show All 36 Publications.
Publications using MGM00 Applications Species
SJ Holtkamp, LM Ince, C Barnoud, MT Schmitt, F Sinturel, V Pilorz, R Pick, S Jemelin, M Mühlstädt, WH Boehncke, J Weber, D Laubender, J Philippou-, CS Chen, L Holtermann, D Vestweber, M Sperandio, BU Schraml, C Halin, C Dibner, H Oster, J Renkawitz, C Scheierman Circadian clocks guide dendritic cells into skin lymphatics Nature Immunology, 2021-10-18;22(11):1375-1381. 2021-10-18 [PMID: 34663979] (Mouse) Mouse
L Mestre, G Alonso, A Feliú, M Mecha, C Martín, LM Villar, C Guaza Aging and neuroinflammation: Changes in immune cell responses, axon integrity, and motor function in a viral model of progressive multiple sclerosis Aging Cell, 2021-08-06;0(0):e13440. 2021-08-06 [PMID: 34355492] (Mouse) Mouse
AA Hastreiter, GG Dos Santos, EN Makiyama, EWC Santos, P Borelli, RA Fock Effects of protein malnutrition on haematopoietic regulatory activity of bone marrow mesenchymal stem cells The Journal of nutritional biochemistry, 2021-03-08;0(0):108626. 2021-03-08 [PMID: 33705953] (Mouse) Mouse
K Tajiri, K Imanaka-Yo, Y Tsujimura, K Matsuo, M Hiroe, K Aonuma, M Ieda, Y Yasutomi A New Mouse Model of Chronic Myocarditis Induced by Recombinant Bacille Calmette-Gu�rin Expressing a T-Cell Epitope of Cardiac Myosin Heavy Chain-&alpha International Journal of Molecular Sciences, 2021-01-14;22(2):. 2021-01-14 [PMID: 33466825] (Mouse) Mouse
DH Park, B Han, MS Shin, GS Hwang Enhanced Intestinal Immune Response in Mice after Oral Administration of Korea Red Ginseng-Derived Polysaccharide Polymers, 2020-09-24;12(10):. 2020-09-24 [PMID: 32987851] (Mouse) Mouse
S Wang, A Raybuck, E Shiuan, SH Cho, Q Wang, DM Brantley-S, D Edwards, MM Allaman, J Nathan, KT Wilson, D DeNardo, S Zhang, R Cook, M Boothby, J Chen Selective inhibition of mTORC1 in tumor vessels increases antitumor immunity JCI Insight, 2020-08-06;5(15):. 2020-08-06 [PMID: 32759497] (Mouse) Mouse
V Chitu, F Biundo, GGL Shlager, ES Park, P Wang, ME Gulinello, ? Gokhan, HC Ketchum, K Saha, MA DeTure, DW Dickson, ZK Wszolek, D Zheng, AL Croxford, B Becher, D Sun, MF Mehler, ER Stanley Microglial Homeostasis Requires Balanced CSF-1/CSF-2 Receptor Signaling Cell Rep, 2020-03-03;30(9):3004-3019.e5. 2020-03-03 [PMID: 32130903] (Mouse) Mouse
M Hetzel, E Lopez-Rodr, A Mucci, AHH Nguyen, T Suzuki, K Shima, T Buchegger, S Dettmer, T Rodt, JP Bankstahl, P Malik, L Knudsen, A Schambach, G Hansen, BC Trapnell, N Lachmann, T Moritz Effective hematopoietic stem cell-based gene therapy in a murine model of hereditary pulmonary alveolar proteinosis Haematologica, 2019-07-09;105(4):1147-1157. 2019-07-09 [PMID: 31289207] (Mouse) Mouse
J Yan, Q Zhao, K Gabrusiewi, LY Kong, X Xia, J Wang, M Ott, J Xu, RE Davis, L Huo, G Rao, SC Sun, SS Watowich, AB Heimberger, S Li FGL2 promotes tumor progression in the CNS by suppressing CD103+ dendritic cell differentiation Nat Commun, 2019-01-25;10(1):448. 2019-01-25 [PMID: 30683885] (Mouse) Mouse
V Kemp, DJM van den Wo, MGM Camps, T van Hall, P Kinderman, N Pronk-van, RC Hoeben Arming oncolytic reovirus with GM-CSF gene to enhance immunity Cancer Gene Ther., 2018-11-23;0(0):. 2018-11-23 [PMID: 30467340]
Show All 36 Publications.

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Bioinformatics

Gene Symbol Csf2