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Mouse CXCL1/KC Quantikine ELISA Kit, 2 Plate

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STAT3 regulates chemoattractive CXCL1 expression.(a) ELISA of CXCL1 levels in lung lysates and BAL at 6 and 13 weeks post AdCre. Data were analysed by Student’s t-test and shown as mean±s.d., n≥7 mice per genotype ...read more

Product Details

Summary
Reactivity MuSpecies Glossary
Applications ELISA
Conjugate
HRP

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Catalog# & Conjugate Size Price

Mouse CXCL1/KC Quantikine ELISA Kit, 2 Plate Summary

Background
The Quantikine Mouse KC Immunoassay is a 4.5 hour solid phase ELISA designed to measure mouse KC in cell culture supernates and mouse serum. It contains E. coli-expressed recombinant mouse KC and antibodies raised against the recombinant factor. This Immunoassay has been shown to quantitate the recombinant mouse KC accurately. Results obtained using natural mouse KC showed dose-resp...onse curves that were parallel to the standard curves obtained using the recombinant kit standards. These results indicate that this kit can be used to determine relative mass values for natural mouse KC.
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Specificity
Natural and recombinant mouse KC
Source
N/A
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
Cxcl1

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using
MKC00B in the following applications:

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse CXCL1/KC Quantikine ELISA Kit, 2 Plate

  • CINC1
  • CINC-1
  • CXCL1
  • FSP
  • GRO alpha
  • GRO1
  • GROa
  • KC
  • MGSA
  • MGSA-a
  • MGSA-alpha
  • NAP-3
  • SCYB1

Background

CXCL1/GRO alpha, also known as KC in mouse and CINC-1 in rat, is a member of the CXC family of chemokines. Human CXCL1/GRO alpha is 107 amino acids (aa) in length with a predicted molecular weight of 11 kDa. The mouse and rat orthologs share 57% and 59% amino acid sequence identity with the human protein, respectively. Genome-wide analysis suggests that the protein encoded by the mouse Cxcl3 gene is homologous to human CXCL1/GRO alpha protein. Human CXCL1/GRO alpha can be cleaved into three isoforms CXCL1/GRO alpha (aa 4-73), CXCL1/GRO alpha (aa 5-73), and CXCL1/GRO alpha (aa 6-73) which show higher activity than the full length protein. CXCL1/GRO alpha is secreted by mast cells and macrophages whereupon it acts as a chemoattractant for neutrophils.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for CXCL1/GRO alpha/KC/CINC-1 (MKC00B)(201)

We have publications tested in 5 confirmed species: Human, Mouse, Rat, Transgenic Mouse, Xenograft.

We have publications tested in 1 application: ELISA Capture.


Filter By Application
ELISA Capture
(1)
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Human
(1)
Mouse
(197)
Rat
(1)
Transgenic Mouse
(1)
Xenograft
(1)
All Species
Showing Publications 1 - 10 of 201. Show All 201 Publications.
Publications using MKC00B Applications Species
Wang, L;Lin, B;Zhai, M;Hull, L;Cui, W;Xiao, M; Endothelial Dysfunction and Impaired Wound Healing Following Radiation Combined Skin Wound Injury International journal of molecular sciences 2024-11-21 [PMID: 39684207] (Mouse) Mouse
Di, Y;Wang, Z;Xiao, J;Zhang, X;Ye, L;Wen, X;Qin, J;Lu, L;Wang, X;He, W; ACSL6-activated IL-18R1-NF-?B promotes IL-18-mediated tumor immune evasion and tumor progression Science advances 2024-09-20 [PMID: 39292786] (Mouse) Mouse
Bernard, A;Eggstein, C;Tang, L;Keller, M;Körner, A;Mirakaj, V;Rosenberger, P; Plexin C1 influences immune response to intracellular LPS and survival in murine sepsis Journal of biomedical science 2024-08-21 [PMID: 39169397] (Transgenic Mouse) Transgenic Mouse
Yan, H;Sasaki, T;Gon, Y;Nishiyama, K;Kanki, H;Mochizuki, H; Driver gene KRAS aggravates cancer-associated stroke outcomes Thrombosis research 2023-11-19 [PMID: 38029547] (Xenograft) Xenograft
Jung, SH;Chung, KS;Na, CS;Ahn, HS;Shin, YK;Lee, KT; Ethanol Extracts from the Aerial Parts of Inula japonica and Potentilla chinensis Alleviate Airway Inflammation in Mice That Inhaled Particulate Matter 10 and Diesel Particulate Matter Nutrients 2023-10-29 [PMID: 37960252] (Mouse) Mouse
Sha, L;Li, J;Shen, H;Wang, Q;Meng, P;Zhang, X;Deng, Y;Zhu, W;Xu, Q; LHPP-mediated inorganic pyrophosphate hydrolysis-driven lysosomal acidification in astrocytes regulates adult neurogenesis Cell reports 2023-08-11 [PMID: 37573508] (Mouse) Mouse
Jadi, PK;Dave, A;Issa, R;Tabbasum, K;Okurowska, K;Samarth, A;Urwin, L;Green, LR;Partridge, LJ;MacNeil, S;Garg, P;Monk, PN;Roy, S; Tetraspanin CD9-derived peptides inhibit Pseudomonas aeruginosa corneal infection and aid in wound healing of corneal epithelial cells The ocular surface 2023-07-03 [PMID: 37406881] (Mouse) Mouse
Shinde, P;Kiepas, A;Zhang, L;Sudhir, S;Konstantopoulos, K;Stamatos, NM; Polysialylation controls immune function of myeloid cells in murine model of pneumococcal pneumonia Cell reports 2023-06-19 [PMID: 37339052] (Mouse) Mouse
Fei, X;Huang, J;Li, F;Wang, Y;Shao, Z;Dong, L;Wu, Y;Li, B;Zhang, X;Lv, B;Zhao, Y;Weng, Q;Chen, K;Zhang, M;Yang, S;Zhang, C;Zhang, M;Li, W;Ying, S;Sun, Q;Chen, Z;Shen, H; The Scap-SREBP1-S1P/S2P lipogenesis signal orchestrates the homeostasis and spatiotemporal activation of NF-?B Cell reports 2023-06-01 [PMID: 37267109] (Mouse) Mouse
Graca, FA;Stephan, A;Minden-Birkenmaier, BA;Shirinifard, A;Wang, YD;Demontis, F;Labelle, M; Platelet-derived chemokines promote skeletal muscle regeneration by guiding neutrophil recruitment to injured muscles Nature communications 2023-05-22 [PMID: 37217480] (Mouse) Mouse
Show All 201 Publications.

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Bioinformatics

Gene Symbol Cxcl1