Mouse CX3CL1/Fractalkine Quantikine ELISA Kit

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

CX3CL1/Fractalkine is a transmembrane adhesion protein with a chemokine domain separated from the membrane by a mucin stalk. It is upregulated on many cell types during inflammation. The chemokine and mucin regions can be shed as a soluble chemokine that signals through the receptor CX3CR1. During extravasation, membrane-bound CX3CL1 traps leukocytes, then is cleaved to allow diapedesis. Soluble CX3CL1 protects neurons from microglial neurotoxicity, recruits macrophages for wound healing, recruits osteoclast precursors for bone resorption, and contributes to pathogenesis in coronary artery disease.

We have publications tested in 2 confirmed species: Mouse, Rat.

Showing Publications 1 - 10 of 12. Show All 12 Publications. Collapse Publications.

Publications using MCX310	Applications	Species
Gupta, N;Somayajulu, M;Gurdziel, K;LoGrasso, G;Aziz, H;Rosati, R;McClellan, S;Pitchaikannu, A;Santra, M;Shukkur, M;Stemmer, P;Hazlett, L;Xu, S; The miR-183/96/182 cluster regulates sensory innervation, resident myeloid cells and functions of the cornea through cell type-specific target genes Scientific reports 2024-04-01 [PMID: 38561433] (Mouse)		Mouse
K Inoue, H Morimoto, M Ohgidani, T Ueki Modulation of inflammatory responses by fractalkine signaling in microglia PLoS ONE, 2021-05-21;16(5):e0252118. 2021-05-21 [PMID: 34019594] (Mouse)		Mouse
A Helmke, AM Hüsing, S Gaedcke, N Brauns, MS Balzer, M Reinhardt, M Hiss, N Shushakova, D de Luca, I Prinz, H Haller, S von Vietin Peritoneal dialysate-range hypertonic glucose promotes T cell IL-17 production that induces mesothelial inflammation Eur. J. Immunol., 2020-09-30;0(0):. 2020-09-30 [PMID: 32926407] (Mouse)		Mouse
R Fu, H Guo, S Janga, M Choi, W Klinngam, MC Edman, SF Hamm-Alvar Cathepsin S activation contributes to elevated CX3CL1 (fractalkine) levels in tears of a Sj�gren's syndrome murine model Sci Rep, 2020-01-29;10(1):1455. 2020-01-29 [PMID: 31996771] (Mouse)		Mouse
MD Dorfman, JE Krull, JD Douglass, R Fasnacht, F Lara-Lince, TH Meek, X Shi, V Damian, HT Nguyen, ME Matsen, GJ Morton, JP Thaler Sex differences in microglial CX3CR1 signalling determine obesity susceptibility in mice Nat Commun, 2017-02-22;8(0):14556. 2017-02-22 [PMID: 28223698] (Mouse)		Mouse
Intravenous hMSCs Ameliorate Acute Pancreatitis in Mice via Secretion of Tumor Necrosis Factor-? Stimulated Gene/Protein 6 Sci Rep, 2016-12-05;6(0):38438. 2016-12-05 [PMID: 27917949] (Mouse)		Mouse
Reed , Johanna, Stone , Matthew, Beadnell , Thomas C, Ryu , Yungil, Griffin , Timothy, Schwertfeger , Kathryn Fibroblast growth factor receptor 1 activation in mammary tumor cells promotes macrophage recruitment in a CX3CL1-dependent manner. PLoS ONE, 2012-09-24;7(9):e45877. 2012-09-24 [PMID: 23029290] (Mouse)		Mouse
Tighe RM, Li Z, Potts EN, Frush S, Liu N, Gunn MD, Foster WM, Noble PW, Hollingsworth JW Ozone inhalation promotes CX3CR1-dependent maturation of resident lung macrophages that limit oxidative stress and inflammation. J. Immunol., 2011-09-19;187(9):4800-8. 2011-09-19 [PMID: 21930959] (Mouse)		Mouse
Ishida Y, Hayashi T, Goto T, Kimura A, Akimoto S, Mukaida N, Kondo T Essential involvement of CX3CR1-mediated signals in the bactericidal host defense during septic peritonitis. J. Immunol., 2008-09-15;181(6):4208-18. 2008-09-15 [PMID: 18768878] (Mouse)		Mouse
Trujillo G, O'Connor EC, Kunkel SL, Hogaboam CM A novel mechanism for CCR4 in the regulation of macrophage activation in bleomycin-induced pulmonary fibrosis. Am. J. Pathol., 2008-04-10;172(5):1209-21. 2008-04-10 [PMID: 18403600] (Mouse)		Mouse
Ren T, Chen Q, Tian Z, Wei H Down-regulation of surface fractalkine by RNA interference in B16 melanoma reduced tumor growth in mice. Biochem. Biophys. Res. Commun., 2007-10-29;364(4):978-84. 2007-10-29 [PMID: 17971299] (Mouse)		Mouse
Laragione T, Yarlett NC, Brenner M, Mello A, Sherry B, Miller EJ, Metz CN, Gulko PS The arthritis severity quantitative trait loci Cia4 and Cia6 regulate neutrophil migration into inflammatory sites and levels of TNF-alpha and nitric oxide. J. Immunol., 2007-02-15;178(4):2344-51. 2007-02-15 [PMID: 17277140] (Rat)		Rat
Show All 12 Publications. Collapse Publications.

Array MCX310

• CX3CL1/Fractalkine Antibodies
• CX3CL1/Fractalkine Antibody Pair
• CX3CL1/Fractalkine ELISA Kit
• CX3CL1/Fractalkine Proteins
• CX3CL1/Fractalkine ELISAs
• CX3CL1/Fractalkine Proteins and Enzymes