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Mouse CX3CL1/Fractalkine DuoSet ELISA, 15 Plate

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications ELISA
Conjugate
Biotin

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Mouse CX3CL1/Fractalkine DuoSet ELISA, 15 Plate Summary

Source
N/A
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
Cx3cl1

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DY472.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse CX3CL1/Fractalkine DuoSet ELISA, 15 Plate

  • ABCD-3
  • C3Xkine
  • chemokine (C-X3-C motif) ligand 1
  • CX3C membrane-anchored chemokine
  • CX3CL1
  • CXC3
  • CXC3C
  • FKN
  • Fractalkine
  • Neurotactin
  • neurotactin)
  • NTNsmall inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine
  • NTTSmall-inducible cytokine D1
  • SCYD1C-X3-C motif chemokine 1
  • small inducible cytokine subfamily D (Cys-X3-Cys), member-1

Background

CX3CL1/Fractalkine is a transmembrane adhesion protein with a chemokine domain separated from the membrane by a mucin stalk. It is upregulated on many cell types during inflammation. The chemokine and mucin regions can be shed as a soluble chemokine that signals through the receptor CX3CR1. During extravasation, membrane-bound CX3CL1 traps leukocytes, then is cleaved to allow diapedesis. Soluble CX3CL1 protects neurons from microglial neurotoxicity, recruits macrophages for wound healing, recruits osteoclast precursors for bone resorption, and contributes to pathogenesis in coronary artery disease.

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Publications for CX3CL1/Fractalkine (DY472)(11)

We have publications tested in 1 confirmed species: Mouse.


Filter By Application
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Filter By Species
Mouse
(10)
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Showing Publications 1 - 10 of 11. Show All 11 Publications.
Publications using DY472 Applications Species
Ribeiro, R;Silva, EG;Moreira, FC;Gomes, GF;Cussat, GR;Silva, BSR;da Silva, MCM;de Barros Fernandes, H;de Sena Oliveira, C;de Oliveira Guarnieri, L;Lopes, V;Ferreira, CN;de Faria, AMC;Maioli, TU;Ribeiro, FM;de Miranda, AS;Moraes, GSP;de Oliveira, ACP;Vieira, LB; Chronic hyperpalatable diet induces impairment of hippocampal-dependent memories and alters glutamatergic and fractalkine axis signaling Scientific reports 2023-09-29 [PMID: 37773430] (Mouse) Mouse
MCM da Silva, GF Gomes, H de Barros, AM da Silva, AL Teixeira, FA Moreira, AS de Miranda, ACP de Oliveir Inhibition of CSF1R, a receptor involved in microglia viability, alters behavioral and molecular changes induced by cocaine Scientific Reports, 2021-08-06;11(1):15989. 2021-08-06 [PMID: 34362959] (Mouse) Mouse
M McMillin, S Grant, G Frampton, AD Petrescu, E Williams, B Jefferson, A Thomas, A Brahmarout, S DeMorrow Elevated circulating TGF?1 during acute liver failure activates TGF?R2 on cortical neurons and exacerbates neuroinflammation and hepatic encephalopathy in mice J Neuroinflammation, 2019-04-02;16(1):69. 2019-04-02 [PMID: 30940161] (Mouse) Mouse
SA O'Sullivan, M Velasco-Es, KK Dev Demyelination induced by oxidative stress is regulated by sphingosine 1-phosphate receptors Glia, 2017-04-04;0(0):. 2017-04-04 [PMID: 28375547]
Bryan Simons PGI2 Controls Pulmonary NK Cells That Prevent Airway Sensitization to House Dust Mite Allergen J. Immunol, 2016-11-28;0(0):. 2016-11-28 [PMID: 27895167] (Mouse) Mouse
Jesús Ávila Glycogen synthase kinase-3? regulates fractalkine production by altering its trafficking from Golgi to plasma membrane: implications for Alzheimer's disease Cell. Mol. Life Sci., 2016-11-10;0(0):. 2016-11-10 [PMID: 27832289] (Mouse) Mouse
Spada R, Rojas J, Perez-Yague S, Mulens V, Cannata-Ortiz P, Bragado R, Barber D NKG2D ligand overexpression in lupus nephritis correlates with increased NK cell activity and differentiation in kidneys but not in the periphery. J Leukoc Biol, 2015-01-12;97(3):583-98. 2015-01-12 [PMID: 25583577] (Mouse) Mouse
Denoyer A, Godefroy D, Celerier I, Frugier J, Riancho L, Baudouin F, Rostene W, Baudouin C CX3CL1 expression in the conjunctiva is involved in immune cell trafficking during toxic ocular surface inflammation. Mucosal Immunol, 2012-06-13;5(0):702. 2012-06-13 [PMID: 22692452] (Mouse) Mouse
Hughes DJ, Kipar A, Leeming GH, Bennett E, Howarth D, Cummerson JA, Papoula-Pereira R, Flanagan BF, Sample JT, Stewart JP Chemokine binding protein M3 of murine gammaherpesvirus 68 modulates the host response to infection in a natural host. PLoS Pathog., 2011-03-17;7(3):e1001321. 2011-03-17 [PMID: 21445235] (Mouse) Mouse
Cardona AE, Sasse ME, Liu L, Cardona SM, Mizutani M, Savarin C, Hu T, Ransohoff RM Scavenging roles of chemokine receptors: chemokine receptor deficiency is associated with increased levels of ligand in circulation and tissues. Blood, 2008-03-17;112(2):256-63. 2008-03-17 [PMID: 18347198] (Mouse) Mouse
Show All 11 Publications.

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Bioinformatics

Gene Symbol Cx3cl1