Western Blot: mGluR2/3 Antibody [NB100-1760] - Analysis of rat brain shows bands migrating at M r =100,000 and 190,000 which may be a dimer of the smaller band.
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified
Alternate Names for mGluR2/3 Antibody - BSA Free
GLUR2
glutamate metabotropic receptor 2
glutamate receptor, metabotropic 2
GPRC1Bmetabotropic glutamate receptor 2
mGlu2
mGluR2
mGluR2/3
MGLUR2glutamate receptor homolog
Background
Metabotropic glutamate receptors (mGluRs) are G-protein coupled receptors activated by glutamate. Based on sequence similarity, transduction mechanisms and agonist potencies, mGluRs are subdivided into three groups: mGluR1/mGluR5, mGluR2/mGluR3, and mGluR4/mGluR6/mGluR7/mGluR8. mGluRs are widely distributed throughout the nervous system and are expressed by both neurons and glial cells. mGluRs have been suggested to play a variety of functional roles, among which is involvement in synaptic plasticity underlying learning and memory as well as chronic pain.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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