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MAP3K12 Antibody

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Immunocytochemistry/Immunofluorescence: MAP3K12 Antibody [NBP2-58000] - Staining of human cell line U-2 OS shows localization to nucleus & cell junctions.
Immunocytochemistry/ Immunofluorescence: MAP3K12 Antibody [NBP2-58000] - Staining of human cell line U-2 OS shows localization to nucleus & cell junctions.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

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MAP3K12 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: LLHGNTMEKLIKKRNVPQKLSPHSKRPDILKTESLLPKLDAALSGVGLPGCPKGPPSPGRSRRGKTRHRKASAKGSCGDL
Predicted Species
Mouse (100%), Rat (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MAP3K12
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
Application Notes
ICC/IF,Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
MAP3K12 Recombinant Protein Antigen (NBP2-58000PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for MAP3K12 Antibody

  • DLKEC 2.7.11.25
  • Dual leucine zipper bearing kinase
  • EC 2.7.11
  • Leucine-zipper protein kinase
  • MAPK-upstream kinase
  • MEKK12
  • mitogen-activated protein kinase kinase kinase 12
  • Mixed lineage kinase
  • MUKdual leucine zipper kinase DLK
  • protein kinase MUK
  • ZPKleucine zipper protein kinase
  • ZPKP1

Background

The protein encoded by the MAP3K12 gene is a member of serine/threonine protein kinase family. This kinase contains a leucine-zipper domain, and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol MAP3K12