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M-CSFR/CD115 Antibody (AFS98) [DyLight 405]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, Flow, IHC, B/N
Clone
AFS98
Clonality
Monoclonal
Host
Rat
Conjugate
DyLight 405

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP1-43363AF350
Alexa Fluor 405
NBP1-43363AF405
Alexa Fluor 488
NBP1-43363AF488
Alexa Fluor 532
NBP1-43363AF532
Alexa Fluor 594
NBP1-43363AF594
Alexa Fluor 647
NBP1-43363AF647
Alexa Fluor 700
NBP1-43363AF700
Alexa Fluor 750
NBP1-43363AF750
Allophycocyanin
NBP1-43363APC
Allophycocyanin/Cy7
NBP1-43363APCCY7
Biotin
NBP1-43363B
Biotin
NBP1-43592-0.5mg
Biotin
NBP1-43592-0.1mg
Biotin
NBP1-43592-0.05mg
CoraFluor 1
NBP1-43363CL1
DyLight 350
NBP1-43363UV
DyLight 488
NBP1-43363G
DyLight 550
NBP1-43363R
DyLight 594
NBP1-43363DL594
DyLight 650
NBP1-43363C
DyLight 680
NBP1-43363FR
DyLight 755
NBP1-43363IR
FITC
NBP1-43363F
HRP
NBP1-43363H
Janelia Fluor 525
NBP1-43363JF525
Janelia Fluor 549
NBP1-43363JF549
Janelia Fluor 585
NBP1-43363JF585
Janelia Fluor 635
NBP1-43363JF635
Janelia Fluor 646
NBP1-43363JF646
Janelia Fluor 669
NBP1-43363JF669
PE
NBP1-43363PE
PE/Atto594
NBP1-43363PEATT594
PE/Cy5.5
NBP1-43363PECY55
PE/Cy7
NBP1-43363PECY7
PerCP
NBP1-43363PCP
Unconjugated
NBP1-43363-0.1mg
mFluor Violet 450 SE
NBP1-43363MFV450
mFluor Violet 500 SE
NBP1-43363MFV500
mFluor Violet 610 SE
NBP1-43363MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP1-43363-0.1mg
BSA Free
NBP1-43363-0.5mg
BSA Free
NBP1-43363-0.1mg
BSA Free
NBP1-43363-0.05mg
BSA Free
NBP1-43363-0.025mg
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M-CSFR/CD115 Antibody (AFS98) [DyLight 405] Summary

Immunogen
The immunogen for this antibody was CD115.
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Rat
Gene
CSF1R
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Block/Neutralize
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Western Blot

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for M-CSFR/CD115 Antibody (AFS98) [DyLight 405]

  • CD115 antigen
  • CD115
  • c-fms
  • colony stimulating factor 1 receptor
  • CSF1R
  • CSF-1-R
  • CSFR
  • EC 2.7.10.1
  • FMS proto-oncogene
  • FMSFIM2
  • macrophage colony stimulating factor I receptor
  • macrophage colony-stimulating factor 1 receptor
  • McDonough feline sarcoma viral (v-fms) oncogene homolog
  • M-CSF R
  • MCSFR
  • M-CSFR
  • Proto-oncogene c-Fms

Background

MCSF Receptor is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a member of the CSF1/PDGF receptor family of tyrosine protein kinases and contains 5 immunoglobulin like C2 type domains. CD115 is expressed by cells of the monocytic lineage and by progenitor cells. Mutations in this gene have been associated with a predisposition to myeloid malignancy.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CSF1R
Entrez
Uniprot