Home » M-CSFR/CD115 » M-CSFR/CD115 Antibodies » M-CSFR/CD115 Antibody (AFS98) [Janelia Fluor® 585]
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M-CSFR/CD115 Antibody (AFS98) [Janelia Fluor® 585]

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Summary
Product Discontinued
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    • Catalog Number
      NBP1-43363JF585
    • Availability
      Product Discontinued

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M-CSFR/CD115 Antibody (AFS98) [Janelia Fluor® 585] Summary

Immunogen
The immunogen for this antibody was CD115.
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Rat
Gene
CSF1R
Purity
Protein A or G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Block/Neutralize
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for M-CSFR/CD115 Antibody (AFS98) [Janelia Fluor® 585]

  • CD115 antigen
  • CD115
  • c-fms
  • colony stimulating factor 1 receptor
  • CSF1R
  • CSF-1-R
  • CSFR
  • EC 2.7.10.1
  • FMS proto-oncogene
  • FMSFIM2
  • macrophage colony stimulating factor I receptor
  • macrophage colony-stimulating factor 1 receptor
  • McDonough feline sarcoma viral (v-fms) oncogene homolog
  • M-CSF R
  • MCSFR
  • M-CSFR
  • Proto-oncogene c-Fms

Background

MCSF Receptor is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a member of the CSF1/PDGF receptor family of tyrosine protein kinases and contains 5 immunoglobulin like C2 type domains. CD115 is expressed by cells of the monocytic lineage and by progenitor cells. Mutations in this gene have been associated with a predisposition to myeloid malignancy.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CSF1R