Species: Hu
Applications: WB, IHC, B/N
Host: Mouse Monoclonal
Species: Mu
Applications: WB, ICC/IF
Host: Sheep Polyclonal
Species: Mu
Applications: WB, Flow, IHC, B/N
Host: Rat Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA, NULL
Species: Hu
Applications: WB
Species: Hu
Applications: Bioactivity
Species: Hu
Applications: Bioactivity
Species: Mu
Applications: Bioactivity
Description
MCSF Receptor is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a member of the CSF1/PDGF receptor family of tyrosine protein kinases and contains 5 immunoglobulin like C2 type domains. CD115 is expressed by cells of the monocytic lineage and by progenitor cells. Mutations in this gene have been associated with a predisposition to myeloid malignancy.
Bioinformatics
| Entrez |
Mouse
Human
Rat
|
| Uniprot |
Human
Human
Human
Human
Human
|
| Product By Gene ID |
1436 |
| Alternate Names |
- CD115 antigen
- CD115
- C-FMS
- colony stimulating factor 1 receptor
- CSF-1-R
- CSFR
- EC 2.7.10.1
- FMS proto-oncogene
- FMSFIM2
- macrophage colony stimulating factor I receptor
- macrophage colony-stimulating factor 1 receptor
- McDonough feline sarcoma viral (v-fms) oncogene homolog
- Proto-oncogene c-Fms
|
Research Areas for M-CSFR/CD115
Find related products by research area and learn more about each of the different research areas below.
Phospho-SpecificProtein Kinase
![Western Blot M-CSFR/CD115 Antibody (61701) [Unconjugated]](http://images.novusbio.com/fullsize2/M-CSF_R_MAB3291_Western_Blot_7396.jpg)
![Neutralization M-CSFR/CD115 Antibody (61701) [Unconjugated]](http://images.novusbio.com/fullsize2/M-CSF_R_MAB3291_Block_Neutralize_2359.jpg)
![Immunohistochemistry M-CSFR/CD115 Antibody (61701) [Unconjugated]](http://images.novusbio.com/fullsize/antibody/mab3291_human-m-csf-r-cd115-mab-clone-61701-immunohistochemistry-10102023145649..jpg)
![Immunocytochemistry M-CSFR/CD115 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/M-CSF_R_AF3818_Immunocytochemistry_10191.jpg)
![N/A M-CSFR/CD115 [Biotin]](http://images.novusbio.com/fullsize2/DATA_MCSF_R_DY329_ELISA_1932.jpg)
![ELISA M-CSFR/CD115 [Biotin]](http://images.novusbio.com/fullsize2/dyc3268-2_human-phospho-m-csf-r-duoset-ic-elisa-2-plate-elisa-3012202093930.png)
![ELISA M-CSFR/CD115 [Biotin]](http://images.novusbio.com/fullsize2/dyc3268-2_human-phospho-m-csf-r-duoset-ic-elisa-2-plate-elisa-3012202094033.png)
![ELISA M-CSFR/CD115 [Biotin]](http://images.novusbio.com/fullsize2/dyc3268-2_human-phospho-m-csf-r-duoset-ic-elisa-2-plate-elisa-3012202094215.png)
