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Leptin R Antibody (55305) [DyLight 488]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow, ELISA, ELISA(Cap), ELISA(Det)
Clone
55305
Clonality
Monoclonal
Host
Rat
Conjugate
DyLight 488

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Leptin R Antibody (55305) [DyLight 488] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Leptin R
Leu21-Leu840 (predicted)
Accession # P48356
Specificity
Detects mouse Leptin R in ELISAs.
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
LEPR
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA Capture (Matched Antibody Pair)
  • ELISA Detection (Matched Antibody Pair)
  • ELISA Standard (Matched Pair)
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Leptin R Antibody (55305) [DyLight 488]

  • B219
  • CD295 antigen
  • CD295
  • DB
  • DKFZp686B1731
  • huB219
  • LEPR
  • LEP-R
  • Leptin R
  • leptin receptor
  • LeptinR
  • OB R
  • OB receptor
  • OB-R
  • OBRCD295

Background

Leptin receptor (OB-R) is a type I cytokine receptor family protein with significant amino acid sequence identity with gp130, G-CSF receptor, and LIF receptor. An OB-R transcript encodes a soluble form of the receptor. The transcript was reported to be expressed predominantly in regions of the hypothalamus previously thought to be important in body weight regulation. OB-R binds leptin with high affinity and is a potent leptin antagonist. Human OB-R encodes a 1 165 amino acid residue precursor protein with a 22 amino acid residue signal peptide, an 816 amino acid residue extracellular domain, a 21 amino acid residue transmembrane domain and a 303 amino acid residue cytoplasmic domain.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs for Leptin R Antibody (FAB497K) (0)

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol LEPR