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LDLR Antibody (C7) [CoraFluor™ 1]

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Product Details

Summary
Reactivity Hu, Rt, Po, BvSpecies Glossary
Applications WB, ELISA, Flow, Func, ICC/IF, IHC, IP, MS
Clone
C7
Clonality
Monoclonal
Host
Mouse
Conjugate
CoraFluor 1

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP1-78159AF350
Alexa Fluor 405
NBP1-78159AF405
Alexa Fluor 488
NBP1-78159AF488
Alexa Fluor 532
NBP1-78159AF532
Alexa Fluor 594
NBP1-78159AF594
Alexa Fluor 647
NBP1-78159AF647
Alexa Fluor 700
NBP1-78159AF700
Alexa Fluor 750
NBP1-78159AF750
Allophycocyanin
NBP1-78159APC
Allophycocyanin/Cy7
NBP1-78159APCCY7
Biotin
NBP1-78159B
DyLight 350
NBP1-78159UV
DyLight 405
NBP1-78159V
DyLight 488
NBP1-78159G
DyLight 550
NBP1-78159R
DyLight 594
NBP1-78159DL594
DyLight 650
NBP1-78159C
DyLight 680
NBP1-78159FR
DyLight 755
NBP1-78159IR
FITC
NBP1-78159F
HRP
NBP1-78159H
Janelia Fluor 525
NBP1-78159JF525
Janelia Fluor 549
NBP1-78159JF549
Janelia Fluor 585
NBP1-78159JF585
Janelia Fluor 635
NBP1-78159JF635
Janelia Fluor 646
NBP1-78159JF646
Janelia Fluor 669
NBP1-78159JF669
PE
NBP1-78159PE
PE/Atto594
NBP1-78159PEATT594
PE/Cy5.5
NBP1-78159PECY55
PE/Cy7
NBP1-78159PECY7
Unconjugated
NBP1-78159
mFluor Violet 450 SE
NBP1-78159MFV450
mFluor Violet 500 SE
NBP1-78159MFV500
mFluor Violet 610 SE
NBP1-78159MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP1-78159
Azide and BSA Free
NBP2-80833
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LDLR Antibody (C7) [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Immunogen
Partially purified bovine LDL receptor [Swiss-Prot# P01131].
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
LDLR
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Electron Microscopy
  • ELISA
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • In vitro assay
  • Proximity Ligation Assay
  • Radioimmunoassay
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Protein G purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for LDLR Antibody (C7) [CoraFluor™ 1]

  • FH
  • FHC
  • LDL R
  • LDL receptor
  • LDLCQ2
  • LDLR
  • low density lipoprotein receptor
  • low-density lipoprotein receptor class A domain-containing protein 3
  • low-density lipoprotein receptor

Background

The low density lipoprotein (LDL) receptor system coordinates the metabolism of cholesterol, an essential component of the plasma membrane of all mammalian cells. Study of this system has led to an enhanced understanding of the cellular basis of cholesterol homeostasis. It has also brought into focus an important mechanism of metabolic regulation--the process of receptor-mediated endocytosis. Data suggest that the juxtamembranous region of the cytoplasmic domain participates in protein:protein interactions that allow the low density lipoprotein receptor to cluster in coated pits. It has been shown that the family of LDL receptors may serve as viral receptors. Endocytosis of the Flaviviridae viruses, hepatitis C virus, GB virus C/hepatitis G virus, and bovine viral diarrheal virus (BVDV) were shown to be mediated by LDL receptors on cultured cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Bioinformatics

Gene Symbol LDLR