LC3B Antibody - BSA Free

Autophagy (macroautophagy) is a catabolic process which targets intracellular components such as proteins and organelles for degradation. Originally described as a bulk degradation process, current research supports its selective nature (1). Selective autophagy targets specific cellular components for degradation including the endoplasmic reticulum (2) (ER-phagy), mitochondria (3) (mitophagy), peroxisomes (3) (pexophagy), ribosomes (4) (ribophagy) and bacteria (5) (xenophagy). Autophagy relies on a newly formed phagophore, a membrane structure which elongates, sequesters cellular content, and fuses to form a double membrane vesicle known as the autophagosome. Fusion of autophagosomes with lysosomes gives rise to the autophagolysosome, where cellular components are degraded by lysosome hydrolases (1).

Autophagic flux is supported by autophagy-related proteins (Atgs) initially identified in yeast (6,7). The core autophagy machinery is comprised of 17 Atg proteins that play specific roles in autophagosome formation. Among these Atg proteins, Atg8 is not only involved in autophagosome formation but also functions in cargo selection. In mammals, several Atg8 homologues have been identified including microtubule-associated protein 1 light chain 3 alpha, beta and gamma - LC3A, LC3B, and LC3C (8) respectively, as well as GABA type A receptor-associated protein (GABARAP), GABARAP-Like1, and GABARAP-Like2 (9). LC3 (predicted molecular weight 14kD) is ubiquitously expressed and undergoes posttranslational processing after synthesis. First, the cysteine protease Atg4 cleaves a carboxy terminal sequence to generate the cytosolic form LC3-I. Next, E1-like (Atg7) and E2-like (Atg3) enzymes conjugate phosphatidylethanolamine to the newly exposed carboxyterminal glycine, generating LC3-II. Finally, the Atg12-Atg5-Atg16L1 complex participates in LC3 lipidation and autophagosome formation (10). LC3B-I to LC3B-II conversion correlates with autophagosome number and is considered the best marker to monitor autophagy.

References

1. Yu, L., Chen, Y., & Tooze, S. A. (2018). Autophagy pathway: Cellular and molecular mechanisms. Autophagy. https://doi.org/10.1080/15548627.2017.1378838

2. Forrester, A., De Leonibus, C., Grumati, P., Fasana, E., Piemontese, M., Staiano, L., ... Settembre, C. (2019). A selective ER -phagy exerts procollagen quality control via a Calnexin- FAM 134B complex. The EMBO Journal. https://doi.org/10.15252/embj.201899847

3. He, X., Zhu, Y., Zhang, Y., Geng, Y., Gong, J., Geng, J., ... Zhong, H. (2019). RNF34 functions in immunity and selective mitophagy by targeting MAVS for autophagic degradation. The EMBO Journal. https://doi.org/10.15252/embj.2018100978

4. Mathai, B., Meijer, A., & Simonsen, A. (2017). Studying Autophagy in Zebrafish. Cells. https://doi.org/10.3390/cells6030021

5. Losier, T. T., Akuma, M., McKee-Muir, O. C., LeBlond, N. D., Suk, Y., Alsaadi, R. M., ... Russell, R. C. (2019). AMPK Promotes Xenophagy through Priming of Autophagic Kinases upon Detection of Bacterial Outer Membrane Vesicles. Cell Reports. https://doi.org/10.1016/j.celrep.2019.01.062

6. Nakatogawa, H., Suzuki, K., Kamada, Y., & Ohsumi, Y. (2009). Dynamics and diversity in autophagy mechanisms: Lessons from yeast. Nature Reviews Molecular Cell Biology. https://doi.org/10.1038/nrm2708

7. Tsukada, M., & Ohsumi, Y. (1993). Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Letters. https://doi.org/10.1016/0014-5793(93)80398-E

8. Wild, P., McEwan, D. G., & Dikic, I. (2014). The LC3 interactome at a glance. Journal of Cell Science. https://doi.org/10.1242/jcs.140426

9. Igloi, G. L. (2001). Cloning, expression patterns, and chromosome localization of three human and two mouse homologues of GABAA receptor-associated protein. Genomics. https://doi.org/10.1006/geno.2001.6555

10. Glick, D., Barth, S., & Macleod, K. F. (2010). Autophagy: Cellular and molecular mechanisms. Journal of Pathology. https://doi.org/10.1002/path.2697

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 9 confirmed species: Human, Mouse, Rat, Bacteria, Bovine, Canine, Porcine, Primate, Zebrafish.

We have publications tested in 15 applications: B/N, EM, FLOW, IB, ICC, ICC/IF, IF/IHC, IHC, IHC-Fr, IHC-FrFl, IHC-P, IP, In Vivo, KD, WB.

Showing Publications 1 - 10 of 397. Show All 397 Publications. Collapse Publications.

Publications using NB600-1384	Applications	Species
Toriyama K, Okuma T, Abe S et al. In vitro anticancer effect of azithromycin targeting hypoxic lung cancer cells via the inhibition of mitophagy Oncology letters 2024-01-01 [PMID: 38028184]
Omary Z Understanding the role of LRBA in patients with inflammatory bowel disease Thesis
Zhang L, Hu Z, Bai W et al. Fucoxanthin ameliorates traumatic brain injury by suppressing the blood-brain barrier disruption iScience 2023-11-01 [PMID: 37965135] (IHC, WB, Mouse) Details: 1:1000 dilution WB, 1:200 dilution IHC	IHC, WB	Mouse
Hurtado KA, Janda J, Schnellmann RG Lasmiditan restores mitochondrial quality control mechanisms and accelerates renal recovery after ischemia-reperfusion injury Biochemical pharmacology 2023-10-21 [PMID: 37866804] (WB, Mouse)	WB	Mouse
Castillo Bautista CM, Eismann K, Gentzel M et al. Obatoclax Rescues FUS-ALS Phenotypes in iPSC-Derived Neurons by Inducing Autophagy Cells 2023-09-11 [PMID: 37759469]
Khamis T, Alsemeh AE, Alanazi A et al. Breast Milk Mesenchymal Stem Cells and/or Derived Exosomes Mitigated Adenine-Induced Nephropathy via Modulating Renal Autophagy and Fibrotic Signaling Pathways and Their Epigenetic Regulations Pharmaceutics 2023-08-16 [PMID: 37631363] (IHC)	IHC
Barreca F, Aventaggiato M, Vitiello L et al. SIRT5 Activation and Inorganic Phosphate Binding Reduce Cancer Cell Vitality by Modulating Autophagy/Mitophagy and ROS Antioxidants (Basel) 2023-08-18 [PMID: 37627630] (B/N)	B/N
Tamargo-Gómez I, Martínez-García GG, Suárez MF et al. Analysis of ATG4C function in vivo Autophagy 2023-07-17 [PMID: 37459465] (WB, Mouse)	WB	Mouse
Xu Y, Geng Y, Wang H et al. Cyclic helix B peptide alleviates proinflammatory cell death and improves functional recovery after traumatic spinal cord injury Redox biology 2023-05-30 [PMID: 37290302] (ICC/IF, WB, Mouse)	ICC/IF, WB	Mouse
Van Acker ZP, Perdok A, Hellemans R et al. Phospholipase D3 degrades mitochondrial DNA to regulate nucleotide signaling and APP metabolism Nature communications 2023-05-24 [PMID: 37225734] (ICC/IF, WB, Human) Details: WB Dilution 1:1000	ICC/IF, WB	Human
Aventaggiato M, Preziosi A, Cheraghi Bidsorkhi H et al. ZnO Nanorods Create a Hypoxic State with Induction of HIF-1 and EPAS1, Autophagy, and Mitophagy in Cancer and Non-Cancer Cells International journal of molecular sciences 2023-04-09 [PMID: 37108134] (WB, Human)	WB	Human
Aventaggiato M, Barreca F, Vitiello L et al. Role of SIRT3 in Microgravity Response: A New Player in Muscle Tissue Recovery Cells 2023-02-22 [PMID: 36899828] (WB, Mouse)	WB	Mouse
Zhang L, Lin Y, Bai W et al. Human umbilical cord mesenchymal stem cell-derived exosome suppresses programmed cell death in traumatic brain injury via PINK1/Parkin-mediated mitophagy CNS neuroscience & therapeutics 2023-03-08 [PMID: 36890626] (WB, ICC/IF, Mouse)	WB, ICC/IF	Mouse
Bjerregaard VA, Levy AM, Batz MS et al. Involvement of Mitochondrial Dysfunction in FOXG1 Syndrome Genes 2023-01-17 [PMID: 36833172] (WB)	WB
Hoffman HK, Prekeris R HOPS-dependent lysosomal fusion controls Rab19 availability for ciliogenesis in polarized epithelial cells bioRxiv 2023-02-08 [PMID: 36798155] (ICC/IF, WB)	ICC/IF, WB
Su S, Xue Y, Lee SK et al. A dual-activity topoisomerase complex promotes both transcriptional activation and repression in response to starvation Nucleic acids research 2023-02-16 [PMID: 36794732] (WB, Human)	WB	Human
Bhatt V, Lan T, Wang W et al. Inhibition of autophagy and MEK promotes ferroptosis in Lkb1-deficient Kras-driven lung tumors Cell Death & Disease 2023-01-26 [PMID: 36702816] (WB)	WB
Yamashita G, Takano N, Kazama H et al. p53 regulates lysosomal membrane permeabilization as well as cytoprotective autophagy in response to DNA-damaging drugs Cell death discovery 2022-12-29 [PMID: 36581628] (WB, Human) Details: Dilution used in WB 1:4,000	WB	Human
Miller K, Wagner MA, Jassey A, Jackson WT SNAP23 is essential for germination of EV-D68 replication organelles Virology 2022-12-12 [PMID: 36527930] (WB, Human)	WB	Human
Ye S, Fang L, Xie S et al. Resveratrol alleviates postpartum depression-like behavior by activating autophagy via SIRT1 and inhibiting AKT/mTOR pathway Behavioural brain research 2022-11-07 [PMID: 36356720] (WB, IHC-Fr, Mouse)	WB, IHC-Fr	Mouse
Chumpen Ramirez S, GOmez-SAnchez R, Verlhac P et al. --Atg9 interactions via its transmembrane domains are required for phagophore expansion during autophagy Autophagy 2022-11-10 [PMID: 36354155]
Humbert M, Seiler K, Mosimann S, Rentsch V Autophagy-mediated degradation of Fatty Acid Synthase (FASN) facilitates ATRA-induced granulocytic differentiation of acute myeloid leukemia (AML) cells bioRxiv Jan 1 2020 (WB, Human)	WB	Human
Gross D, Bischof H, Maier S et al. IKCa channels control breast cancer metabolism including AMPK-driven autophagy Cell death & disease 2022-10-27 [PMID: 36302750] (WB, Mouse)	WB	Mouse
Neupane N, Rajendran J, Kvist J et al. Inter-organellar and systemic responses to impaired mitochondrial matrix protein import in skeletal muscle Communications biology 2022-10-05 [PMID: 36198903] (WB, Mouse)	WB	Mouse
Khayati K, Bhatt V, Lan T et al. Transient Systemic Autophagy Inhibition Is Selectively and Irreversibly Deleterious to Lung Cancer Cancer Research 2022-12-02 [PMID: 36156071] (WB)	WB
Tong F, Xu L, Xu S, Zhang M. Identification of an autophagy-related 12-lncRNA signature and evaluation of NFYC-AS1 as a pro-cancer factor in lung adenocarcinoma Frontiers in Genetics 2022-08-11 [PMID: 36105077] (IHC)	IHC
Park SS, Kim JI, Lee CH et al. Temsirolimus Enhances Anti-Cancer Immunity by Inducing Autophagy-Mediated Degradation of the Secretion of Small Extracellular Vesicle PD-L1 Cancers (Basel) 2022-08-23 [PMID: 36077620]
Khamis T, Alsemeh AE, Abdullah DM Sacubitril/valsartan (LCZ696) ameliorates hyperthyroid-induced cardiac hypertrophy in male rats through modulation of miR-377, let-7 b, autophagy, and fibrotic signaling pathways Scientific reports 2022-08-27 [PMID: 36030321] (IHC-P, Rat)	IHC-P	Rat
Lee J, Kim SJ, Choi GE et al. Sweet taste receptor agonists attenuate macrophage IL-1 beta expression and eosinophilic inflammation linked to autophagy deficiency in myeloid cells Clinical and translational medicine 2022-08-01 [PMID: 35988262] (IHC-P, Mouse) Details: Dilution used 1:400	IHC-P	Mouse
Zhang L, Liu X, Huang M et al. Metformin Inhibits HaCaT Cell Proliferation Under Hyperlipidemia Through Reducing Reactive Oxygen Species via FOXO3 Activation Clinical, Cosmetic and Investigational Dermatology 2022-07-01 [PMID: 35910506] (WB, Human)	WB	Human
Koike T, Takenaka M, Suzuki N et al. Intracellular ferritin heavy chain plays the key role in artesunate-induced ferroptosis in ovarian serous carcinoma cells Journal of Clinical Biochemistry and Nutrition 2022-01-25 [PMID: 35903602] (WB)	WB
Butera A, Quaranta MT, Crippa L et al. CD147 Targeting by AC-73 Induces Autophagy and Reduces Intestinal Fibrosis Associated with TNBS Chronic Colitis Journal of Crohn's & colitis 2022-07-14 [PMID: 35833587] (WB, Mouse)	WB	Mouse
Lou C, Fang M, Ye S et al. Fluoxetine protects against inflammation and promotes autophagy in mice model of post-traumatic stress disorder Behavioural brain research 2022-07-08 [PMID: 35811001] (WB, Mouse) Details: C57BL/6 Mouse Hippocampus, 1:1000, Fig. 4	WB	Mouse
Davidi S, Jacobovitch S, Shteingauz A et al. Tumor Treating Fields (TTFields) Concomitant with Sorafenib Inhibit Hepatocellular Carcinoma In Vitro and In Vivo Cancers 2022-06-15 [PMID: 35740624] (IHC-P, WB, ICC/IF, Human)	IHC-P, WB, ICC/IF	Human
Kondylis V, Schneider F, Schorn F et al. p62 Promotes Survival and Hepatocarcinogenesis in Mice with Liver-Specific NEMO Ablation Cancers 2022-05-15 [PMID: 35626041] (ICC/IF, WB, Mouse)	ICC/IF, WB	Mouse
Garavaglia B, Vallino L, Ferraresi A et al. Butyrate Inhibits Colorectal Cancer Cell Proliferation through Autophagy Degradation of ?-Catenin Regardless of APC and ?-Catenin Mutational Status Biomedicines 2022-05-13 [PMID: 35625868] (WB, ICC/IF)	WB, ICC/IF
Hoch L, Bourg N, Degrugillier F et al. Dual Blockade of Misfolded Alpha-Sarcoglycan Degradation by Bortezomib and Givinostat Combination Frontiers in Pharmacology 2022-04-27 [PMID: 35571097]
Peugnet V, Chwastyniak M, Mulder P et al. Mitochondrial-Targeted Therapies Require Mitophagy to Prevent Oxidative Stress Induced by SOD2 Inactivation in Hypertrophied Cardiomyocytes Antioxidants (Basel) 2022-04-06 [PMID: 35453408]
Huo Y, Sawant A, Tan Y et al. Tumor suppressor PALB2 maintains redox and mitochondrial homeostasis in the brain and cooperates with ATG7/autophagy to suppress neurodegeneration PLoS genetics 2022-04-01 [PMID: 35404932] (WB, Human)	WB	Human
Chen H, Zhou J, Chen H et al. Bmi-1-RING1B prevents GATA4-dependent senescence-associated pathological cardiac hypertrophy by promoting autophagic degradation of GATA4 Clinical and translational medicine 2022-04-01 [PMID: 35390228] (IHC-Fr, WB, Human, Mouse)	IHC-Fr, WB	Human, Mouse
De Maziere A, van der Beek J, van Dijk S et al. An optimized protocol for immuno-electron microscopy of endogenous LC3 Autophagy 2022-04-07 [PMID: 35387562] (ICC/IF, Human)	ICC/IF	Human
Ito A, Hashimoto M, Tanihata J et al. Involvement of Parkin-mediated mitophagy in the pathogenesis of chronic obstructive pulmonary disease-related sarcopenia Journal of cachexia, sarcopenia and muscle 2022-04-03 [PMID: 35373498] (IF/IHC, Mouse)	IF/IHC	Mouse
Moudio S, Rodin F, Albargothy N et al. Exposure of alpha-Synuclein Aggregates to Organotypic Slice Cultures Recapitulates Key Molecular Features of Parkinson's Disease Frontiers in Neurology 2022-02-16 [PMID: 35309552] (IF/IHC, Rat)	IF/IHC	Rat
Shan Y, Lu C, Wang J et al. IGF-1 contributes to liver cancer development in diabetes patients by promoting autophagy Annals of hepatology 2022-03-13 [PMID: 35297369] (WB, ICC/IF, Human)	WB, ICC/IF	Human
Suliman M, Case K, Schmidtke M et al. Inositol depletion regulates phospholipid metabolism and activates stress signaling in HEK293T cells Biochim Biophys Acta Mol Cell Biol Lipids 2022-03-05 [PMID: 35247568]
Puertas-Neyra K, Galindo-Cabello N, HernAndez-RodrIguez LA et al. Programmed Cell Death and Autophagy in an in vitro Model of Spontaneous Neuroretinal Degeneration Frontiers in neuroanatomy 2022-02-11 [PMID: 35221932] (IHC-Fr, Porcine)	IHC-Fr	Porcine
Beillevaire D, Migneault F, Turgeon J et al. Autolysosomes and caspase-3 control the biogenesis and release of immunogenic apoptotic exosomes Cell death & disease 2022-02-11 [PMID: 35149669] (WB, Human, Mouse)	WB	Human, Mouse
Lin Q, Cao J, Du X et al. The HeyL-Aromatase Axis Promotes Cancer Stem Cell Properties by Endogenous Estrogen-Induced Autophagy in Castration-Resistant Prostate Cancer Frontiers in oncology 2022-01-12 [PMID: 35096586] (WB, Human)	WB	Human
Thakur AK, Luthra-Guptasarma M Differences in Cellular Clearing Mechanisms of Aggregates of Two Subtypes of HLA-B27 Frontiers in immunology 2022-01-10 [PMID: 35082784] (WB, Human)	WB	Human
Krishnan B, Yasuhara T, Rumde P et al. Active RB causes visible changes in nuclear organization The Journal of cell biology 2022-03-07 [PMID: 35019938] (ICC/IF, Human)	ICC/IF	Human
Sendino GarvI E, Masereeuw R, Janssen MJ Bioengineered Cystinotic Kidney Tubules Recapitulate a Nephropathic Phenotype Cells 2022-01-05 [PMID: 35011739] (ICC/IF, Human)	ICC/IF	Human
Stempels FC, Janssens MH, Ter Beest M et al. Novel and conventional inhibitors of canonical autophagy differently affect LC3-associated phagocytosis FEBS letters 2022-01-10 [PMID: 35007347] (WB, Human)	WB	Human
Guo Y, Mao R, Xie Q et al. Francisella novicida Mutant XWK4 Triggers Robust Inflammasome Activation Favoring Infection Frontiers in Cell and Developmental Biology 2021-11-18 [PMID: 34869331] (WB)	WB
Xu Y, Hu X, Li F Et al. GDF-11 Protects the Traumatically Injured Spinal Cord by Suppressing Pyroptosis and Necroptosis via TFE3-Mediated Autophagy Augmentation Oxidative medicine and cellular longevity 2021-10-19 [PMID: 34712387] (Mouse)		Mouse
Li R, Hao Y, Wang Q Et al. ECHS1, an interacting protein of LASP1, induces sphingolipid-metabolism imbalance to promote colorectal cancer progression by regulating ceramide glycosylation Cell death & disease 2021-10-06 [PMID: 34615856] (WB, Human)	WB	Human
Smith SJ, Fabian L, Sheikh A Et al. Lysosomes and the pathogenesis of merosin-deficient congenital muscular dystrophy Human molecular genetics 2021-09-25 [PMID: 34568901]
Tu YXI, Sydor AM, Coyaud E et al. Global Proximity Interactome of the Human Macroautophagy Pathway Autophagy 2022-05-04 [PMID: 34524948]
McCarthy CG, Chakraborty S, Singh G et al. Ketone body beta-hydroxybutyrate is an autophagy-dependent vasodilator JCI insight 2021-09-09 [PMID: 34499623] (WB, Rat)	WB	Rat
Miyazaki M, Hiramoto M, Takano N et al. Targeted disruption of GAK stagnates autophagic flux by disturbing lysosomal dynamics International journal of molecular medicine 2021-10-01 [PMID: 34468012] (WB, Human)	WB	Human
Bellanger D, Dziagwa C, Guimaraes C et al. Adipocytes Promote Breast Cancer Cell Survival and Migration through Autophagy Activation Cancers (Basel) 2021-08-03 [PMID: 34359819] (WB, B/N)	WB, B/N
Hattori K, Takano N, Kazama H et al. Induction of synergistic non apoptotic cell death by simultaneously targeting proteasomes with bortezomib and histone deacetylase 6 with ricolinostat in head and neck tumor cells Oncology Letters 2021-07-22 [PMID: 34345305] (WB)	WB
Wang X, Zhu Yt, Zhu Y Et Al. Long-term running exercise alleviates cognitive dysfunction in APP/PSEN1 transgenic mice via enhancing brain lysosomal function Acta pharmacologica Sinica 2021-07-16 [PMID: 34272505] (WB)	WB
Tokarchuk I, Janser Fa, Schlafli Am Et Al. Increased LAMP2A levels correlate with a shorter disease-free survival of HER2 negative breast cancer patients and increased breast cancer cell viability Biochemical and biophysical research communications 2021-07-03 [PMID: 34229122] (WB)	WB
Fontaine A, Bellanger D, Guibon R Et Al. Lipophagy and prostate cancer: association with disease aggressiveness and proximity to periprostatic adipose tissue The Journal of pathology 2021-07-05 [PMID: 34219239] (WB)	WB
Akoumianaki T, Vaporidi K, Diamantaki E et al. Uncoupling of IL-6 signaling and LC3-associated phagocytosis drives immunoparalysis during sepsis Cell host & microbe 2021-06-25 [PMID: 34214493]
Devenport SN, Singhal R, Radyk MD et al. Colorectal cancer cells utilize autophagy to maintain mitochondrial metabolism for cell proliferation under nutrient stress JCI insight 2021-06-17 [PMID: 34138755] (IHC-P, Mouse)	IHC-P	Mouse
Molinari F, Feraco A, Mirabilii S et al. SIRT5 Inhibition Induces Brown Fat-Like Phenotype in 3T3-L1 Preadipocytes Cells 2021-05-07 [PMID: 34066961] (WB, Mouse)	WB	Mouse
Orhon I, Rocchi C, Villarejo-Zori B et al. Autophagy induction during stem cell activation plays a key role in salivary gland self-renewal Autophagy 2021-05-19 [PMID: 34009100]
Ferro I, Gavini J, Gallo S et al. The human vault RNA enhances tumorigenesis and chemoresistance through the lysosome in hepatocellular carcinoma Autophagy 2022-01-02 [PMID: 33960270] (In Vivo)	In Vivo
Ovejero-SAnchez M, GonzAlez-Sarmiento R, Herrero AB Synergistic effect of Chloroquine and Panobinostat in ovarian cancer through induction of DNA damage and inhibition of DNA repair Neoplasia (New York, N.Y.) 2021-04-27 [PMID: 33930758] (WB, ICC/IF, Human)	WB, ICC/IF	Human
SchlAfli A, Tokarchuk I, Parejo S et al. ALK inhibition activates LC3B-independent, protective autophagy in EML4-ALK positive lung cancer cells Scientific Reports 2021-12-01 [PMID: 33907223] (WB, Human)	WB	Human
Li J, Tian M, Hua T et al. Combination of autophagy and NFE2L2/NRF2 activation as a treatment approach for neuropathic pain Autophagy 2021-04-09 [PMID: 33834930]
Tamargo-GOmez I, MartInez-GarcIa GG, SuArez MF et al. ATG4D is the main ATG8 delipidating enzyme in mammalian cells and protects against cerebellar neurodegeneration Cell death and differentiation 2021-04-01 [PMID: 33795848]
Luo Y, Zheng S, Wu Q et al. Long noncoding RNA (lncRNA) EIF3J-DT induces chemoresistance of gastric cancer via autophagy activation Autophagy 2021-03-25 [PMID: 33764843]
Shen Z, Ji K, Cai Z et al. Inhibition of HDAC6 by Tubastatin A reduces chondrocyte oxidative stress in chondrocytes and ameliorates mouse osteoarthritis by activating autophagy Aging (Albany NY) 2021-04-15 [PMID: 33744850] (B/N)	B/N
Humbert M, Seiler K, Mosimann S et al. Reducing FASN expression sensitizes acute myeloid leukemia cells to differentiation therapy Cell Death Differ 2021-03-20 [PMID: 33742137]
Chuang K, Chen F, Tsai M, Shieh J EGR 1 plays a protective role in AMPK inhibitor compound C induced apoptosis through ROS induced ERK activation in skin cancer cells Oncology Letters 2021-02-19 [PMID: 33732380] (WB, Human)	WB	Human
Janser, F A, Ney, P Et al. The Chick Chorioallantoic Membrane (CAM) Assay as a Three-dimensional Model to Study Autophagy in Cancer Cells. Bio Protoc 2019-07-05 [PMID: 33654803] (ICC/IF, Mouse)	ICC/IF	Mouse
Saulle E, Spinello I, Quaranta MT et al. Targeting Lactate Metabolism by Inhibiting MCT1 or MCT4 Impairs Leukemic Cell Proliferation, Induces Two Different Related Death-Pathways and Increases Chemotherapeutic Sensitivity of Acute Myeloid Leukemia Cells Frontiers in Oncology 2021-02-05 [PMID: 33614502] (WB)	WB
Mercier AE, Prudent R, Pepper MS et al Characterization of Signalling Pathways That Link Apoptosis and Autophagy to Cell Death Induced by Estrone Analogues Which Reversibly Depolymerize Microtubules Molecules 2021-02-12 [PMID: 33572896] (FLOW, Human) Details: Citation using the Alexa Fluor 488 version of this antibody.	FLOW	Human
Rai P, Janardhan KS, Meacham J, et al. IRGM1 links mitochondrial quality control to autoimmunity Nature immunology 2021-01-28 [PMID: 33510463] (ICC/IF)	ICC/IF
Park J, Choi H, Kim YD, et al. Aberrant role of ALK in tau proteinopathy through autophagosomal dysregulation Molecular psychiatry 2021-01-15 [PMID: 33452442] (ICC/IF, WB, Human)	ICC/IF, WB	Human
Zhou X, Zhu X, Li C, et al. Stearoyl-CoA Desaturase-Mediated Monounsaturated Fatty Acid Availability Supports Humoral Immunity Cell reports 2021-01-05 [PMID: 33406440] (WB, Mouse)	WB	Mouse
Kong J, Wang J, Gong X et al. Punicalagin Inhibits Tert-Butyl Hydroperoxide-Induced Apoptosis and Extracellular Matrix Degradation in Chondrocytes by Activating Autophagy and Ameliorates Murine Osteoarthritis Drug design, development and therapy 2020-12-15 [PMID: 33364748]
Schulze RJ, Krueger EW, Weller SG et al. Direct lysosome-based autophagy of lipid droplets in hepatocytes Proceedings of the National Academy of Sciences 2020-12-22 [PMID: 33288726] (B/N)	B/N
Li Y, Pan Y, Cao S et al. Podocyte EGFR Inhibits Autophagy Through Upregulation of Rubicon in Type II Diabetic Nephropathy Diabetes 2020-11-25 [PMID: 33239448]
Khayati K, Bhatt V, Hu ZS et al. Autophagy compensates for Lkb1 loss to maintain adult mice homeostasis and survival eLife 2020-11-25 [PMID: 33236987] (WB)	WB
Machiela E, Jeloka R, Caron NS et al. The interaction of aging and oxidative stress contributes to pathogenesis in mouse and human Huntington disease neurons Front Aging Neurosci 2020-11-16 [PMID: 33192449]
Takeda A, Takano N, Kokuba H et al. Macrolide antibiotics enhance the antitumor effect of lansoprazole resulting in lysosomal membrane permeabilization associated cell death Int J Oncol 2020-10-21 [PMID: 33173988] (WB, Human)	WB	Human
Kwon Y, Bang Y, Moon SH et al. Amitriptyline interferes with autophagy-mediated clearance of protein aggregates via inhibiting autophagosome maturation in neuronal cells Cell Death Dis 2020-10-17 [PMID: 33070168]
LosmanovA T, Janser FA, Humbert M et al. Chaperone-Mediated Autophagy Markers LAMP2A and HSC70 Are Independent Adverse Prognostic Markers in Primary Resected Squamous Cell Carcinomas of the Lung Oxid Med Cell Longev 2020-09-21 [PMID: 33029283] (IF/IHC, Human)	IF/IHC	Human
Li Y, Xiang J, Zhang J et al. Inhibition of Brd4 by JQ1 Promotes Functional Recovery From Spinal Cord Injury by Activating Autophagy Frontiers in cellular neuroscience 2020-09-02 [PMID: 32982695] (ICC/IF, WB, Mouse)	ICC/IF, WB	Mouse
Peintner L, Venkatraman A, Waeldin A et al. Loss of PKD1/polycystin-1 impairs lysosomal activity in a CAPN (calpain)-dependent manner Autophagy 2020-09-24 [PMID: 32967521] (WB, Mouse)	WB	Mouse
Chen JL, Wang XX, Chen L et al. A sphingosine kinase 2-mimicking TAT-peptide protects neurons against ischemia-reperfusion injury by activating BNIP3-mediated mitophagy Neuropharmacology 2020-09-20 [PMID: 32966847] (WB, Mouse)	WB	Mouse
Liu EA, Schultz ML, Mochida C et al. Fbxo2 mediates clearance of damaged lysosomes and modifies neurodegeneration in the Niemann-Pick C brain JCI Insight 2020-09-15 [PMID: 32931479] (ICC/IF, Human, Mouse)	ICC/IF	Human, Mouse
Yang RZ, Xu WN, Zheng HL et al. Involvement of oxidative stress-induced annulus fibrosus cell and nucleus pulposus cell ferroptosis in intervertebral disc degeneration pathogenesis J. Cell. Physiol. 2020-09-06 [PMID: 32892384] (WB)	WB
Chen L, Xia YF, Shen SF et al. Syntaxin 17 inhibits ischemic neuronal injury by resuming autophagy flux and ameliorating endoplasmic reticulum stress Free Radic. Biol. Med. 2020-08-20 [PMID: 32828953] (KD, WB, Mouse)	KD, WB	Mouse
Bernard M, Cardin GB, Cahuzac M et al. Dual Inhibition of Autophagy and PI3K/AKT/MTOR Pathway as a Therapeutic Strategy in Head and Neck Squamous Cell Carcinoma Cancers (Basel) 2020-08-21 [PMID: 32825725] (WB, Human)	WB	Human
Zhou K, Zheng Z, Li Y et al. TFE3, a potential therapeutic target for Spinal Cord Injury via augmenting autophagy flux and alleviating ER stress Theranostics 2020-07-23 [PMID: 32802192] (Mouse)		Mouse
Zhou X, Brooks M, Jiang P et al. Loss of Tmem106b exacerbates FTLD pathologies and causes motor deficits in progranulin-deficient mice EMBO Rep. 2020-08-05 [PMID: 32761777]
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Liu HM, Ferrington DA, Baumann CW, Thompson LV. Denervation-Induced Activation of the Standard Proteasome and Immunoproteasome. PLoS ONE. 2016-11-22 [PMID: 27875560] (WB, Mouse)	WB	Mouse
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Qi X, Man SM, Malireddi RK et al. Cathepsin B modulates lysosomal biogenesis and host defense against Francisella novicida infection. J. Exp. Med. 2016-08-22 [PMID: 27551156] (WB, ICC/IF, Mouse)	WB, ICC/IF	Mouse
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Lee SH, Du J, Stitham J et al. Inducing mitophagy in diabetic platelets protects against severe oxidative stress. EMBO Mol Med. 2016-05-23 [PMID: 27221050] (FLOW, Human) Details: This publication used the AF488 conjugated form of this antibody (NB600-1384AF488)	FLOW	Human
Alan L, Spacek T, Pajuelo Reguera D et al. Mitochondrial nucleoid clusters protect newly synthesized mtDNA during Doxorubicin- and Ethidium Bromide-induced mitochondrial stress. Toxicol. Appl. Pharmacol. 2016-04-19 [PMID: 27102948] (WB, Human)	WB	Human
Boman A, Svensson S, Boxer A et al. Distinct Lysosomal Network Protein Profiles in Parkinsonian Syndrome Cerebrospinal Fluid. J Parkinsons Dis 2016-04-02 [PMID: 27061067] (WB)	WB
Gschweitl M, Ulbricht A, Barnes CA et al. A SPOPL/Cullin-3 ubiquitin ligase complex regulates endocytic trafficking by targeting EPS15 at endosomes. Elife. 2016-04-22 [PMID: 27008177] (WB, Human)	WB	Human
Bauckman KA, Mysorekar IU. Ferritinophagy drives uropathogenic Escherichia coli persistence in bladder epithelial cells. Autophagy. 2016-03-22 [PMID: 27002654] (WB, Human)	WB	Human
Santanam U, Banach-Petrosky W, Abate-Shen C et al. Atg7 cooperates with Pten loss to drive prostate cancer tumor growth. CSH Press. 2016-02-15 [PMID: 26883359] (IF/IHC, WB, Mouse)	IF/IHC, WB	Mouse
Myeku N, Clelland CL, Emrani S et al. Tau-driven 26S proteasome impairment and cognitive dysfunction can be prevented early in disease by activating cAMP-PKA signaling. Nat. Med. 2016-01-01 [PMID: 26692334] (WB, Mouse)	WB	Mouse
Wang Y, Chen B, Longtine MS, Nelson DM Punicalagin promotes autophagy to protect primary human syncytiotrophoblasts from apoptosis. Reproduction 2016-02-01 [PMID: 26659860]
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Koukourakis MI, Kalamida D, Giatromanolaki A et al. Autophagosome Proteins LC3A, LC3B and LC3C Have Distinct Subcellular Distribution Kinetics and Expression in Cancer Cell Lines. PLoS One 2015-01-01 [PMID: 26378792] (WB, Human)	WB	Human
Brigger D, Schlafli AM, Garattini E, Tschan MP. Activation of RARa induces autophagy in SKBR3 breast cancer cells and depletion of key autophagy genes enhances ATRA toxicity. Cell Death Dis 2015-08-28 [PMID: 26313912] (WB, ICC/IF, Human)	WB, ICC/IF	Human
Chourasia AH, Tracy K, Frankenberger C et al. Mitophagy defects arising from BNip3 loss promote mammary tumor progression to metastasis. EMBO Rep 2015-09-01 [PMID: 26232272] (WB)	WB
Dever SM, Rodriguez M, Lapierre J et al. Differing roles of autophagy in HIV-associated neurocognitive impairment and encephalitis with implications for morphine co-exposure. Front Microbiol 2015-01-01 [PMID: 26217309] (IF/IHC)	IF/IHC
Rushika M. Perera, Svetlana Stoykova, Brandon N. Nicolay et al. Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism. Nature 2015-07-13 [PMID: 26168401] (WB, Human)	WB	Human
Owczarczyk AB, Schaller MA, Reed M et al. Sirtuin 1 Regulates Dendritic Cell Activation and Autophagy during Respiratory Syncytial Virus-Induced Immune Responses J. Immunol. 2015-07-08 [PMID: 26157176] (ICC/IF, Mouse)	ICC/IF	Mouse
Schlafli AM, Berezowska S, Adams O et al. Reliable LC3 and p62 autophagy marker detection in formalin fixed paraffin embedded human tissue by immunohistochemistry. Eur J Histochem 2015-01-01 [PMID: 26150155] (Human)		Human
Hu G, McQuiston T, Bernard A et al. A conserved mechanism of TOR-dependent RCK-mediated mRNA degradation regulates autophagy. Nat Cell Biol 2015-07-01 [PMID: 26098573] (IP)	IP
Dickinson JD, Alevy Y, Malvin NP et al. IL13 activates autophagy to regulate secretion in airway epithelial cells. Autophagy 2015-06-10 [PMID: 26062017] (WB)	WB
Milkereit R, Persaud A, Vanoaica L et al. LAPTM4b recruits the LAT1-4F2hc Leu transporter to lysosomes and promotes mTORC1 activation. Nat Commun. 2015-05-22 [PMID: 25998567] (ICC/IF, WB, Human) Details: LC3B/MAP1LC3B antibody was used for WB and ICC-IF assays on samples from HeLa cells which were stably knocked down for LAPTM4b or control and were starved - treated with 50?uM chloroquine. ICC-IF assay employed 4% paraformaldehyde fixation, permeablization for 15?minutes with cold 95% methanol, 1 hour blocking with 1% BSA, use of primary at 1:200 dilution with 4C ON incubation.	ICC/IF, WB	Human
Del Mar N, von Buttlar X, Yu AS et al. A novel closed-body model of spinal cord injury caused by high-pressure air blasts produces extensive axonal injury and motor impairments. Exp. Neurol. 2015-05-07 [PMID: 25957630] (ICC/IF, Mouse)	ICC/IF	Mouse
Zhang L, Wang H, Ding K, Xu J. FTY720 induces autophagy-related apoptosis and necroptosis in human glioblastoma cells. Toxicol. Lett. 2015-07-02 [PMID: 25939952] (ICC/IF, WB, Human)	ICC/IF, WB	Human
Munoz-Saez E, de Munck Garcia E, Arahuetes Portero RM et al. Analysis of B-N-methylamino-l-alanine (L-BMAA) neurotoxicity in rat cerebellum. Neurotoxicology. 2015-04-18 [PMID: 25898785] (WB, Rat)	WB	Rat
Akizu N, Cantagrel V, Zaki MS et al. Biallelic mutations in SNX14 cause a syndromic form of cerebellar atrophy and lysosome-autophagosome dysfunction Nat. Genet. 2015-05-01 [PMID: 25848753] (WB, Human)	WB	Human
Sharifi MN, Mowers EE, Drake LE, Macleod KF. Measuring autophagy in stressed cells. Methods Mol. Biol. 2015-03-25 [PMID: 25804753] (WB, Human)	WB	Human
Stander XX, Stander BA, Joubert AM. Synergistic Anticancer Potential of Dichloroacetate and Estradiol Analogue Exerting their Effect via ROS-JNK-Bcl-2-Mediated Signalling Pathways Cell. Physiol. Biochem. 2015-03-31 [PMID: 25791820] (FLOW, Human)	FLOW	Human
Fjeld K, Weiss FU, Lasher D et al. A recombined allele of the lipase gene CEL and its pseudogene CELP confers susceptibility to chronic pancreatitis. Nat. Genet. 2015-03-16 [PMID: 25774637] (WB, Human)	WB	Human
Strohecker AM, Joshi S, Possemato R et al. Identification of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase as a novel autophagy regulator by high content shRNA screening. Oncogene. 2015-03-16 [PMID: 25772235] (WB, Human)	WB	Human
Wengrod J, Wang D, Weiss S et al. Phosphorylation of eIF2alpha triggered by mTORC1 inhibition and PP6C activation is required for autophagy and is aberrant in PP6C-mutated melanoma. Sci Signal 2015-03-10 [PMID: 25759478] (IF/IHC, Human)	IF/IHC	Human
Polletta L, Vernucci E, Carnevale I et al. SIRT5 regulation of ammonia-induced autophagy and mitophagy. Autophagy 2015-01-01 [PMID: 25700560]
Xie X, Koh JY, Price S et al. Atg7 overcomes senescence and promotes growth of BRAFV600E-driven melanoma Cancer Discov. 2015-02-11 [PMID: 25673642] (WB, Mouse)	WB	Mouse
Bernard M, DieudeM, Yang B et al. Autophagy fosters myofibroblast differentiation through MTORC2 activation and downstream upregulation of CTGF. Autophagy. 2014-12-12 [PMID: 25495560] (WB)	WB
Yang Q, Stevenson HL, Scott MJ, Ismail N. Type I Interferon Contributes to Noncanonical Inflammasome Activation, Mediates Immunopathology, and Impairs Protective Immunity during Fatal Infection with Lipopolysaccharide-Negative Ehrlichiae. Am. J. Pathol. 2014-12-04 [PMID: 25481711] (WB, Mouse) Details: LC3B antibody used for WB at dilution 1:2500 on liver lysates of naive, Nlrp3-/- , Casp1-/-, Ifnar1-/- and WT mice (Figure 10A).	WB	Mouse
Lee Jm, Wagner M, Xiao R et al. Nutrient-sensing nuclear receptors coordinate autophagy. Nature. 2014-11-12 [PMID: 25383539]
Toops Ka, Tan Lx, Jiang Z et al. Cholesterol-mediated activation of acid sphingomyelinase disrupts autophagy in the retinal pigment epithelium Mol. Biol. Cell et al. 2014-11-05 [PMID: 25378587] (WB, Porcine) Details: LC3B/MAP1LC3B antibody used for WB on porcine primary retinal pigment epithelium/RPE cells.	WB	Porcine
Wang J, Gu S, Huang J et al. Inhibition of autophagy potentiates the efficacy of Gli inhibitor GAnT-61 in MYCn-amplified neuroblastoma cells. BMC Cancer. 2014-10-23 [PMID: 25323222] (WB, Human)	WB	Human
Mathew TS, Ferris RK, Downs RM et al. Caffeine promotes autophagy in skeletal muscle cells by increasing the calcium-dependent activation of AMP-activated protein kinase. Biochem. Biophys. Res. Commun. 2014-09-28 [PMID: 25268764] (WB, ICC/IF, Mouse) Details: LC3B antibody used for WB and ICC-IF in experiments involving C2C12 cells (mouse myoblast cell line).	WB, ICC/IF	Mouse
Juarez E, Carranza C, Hernandez-Sanchez F et al. Nucleotide-oligomerizing domain-1 (NOD1) receptor activation induces pro-inflammatory responses and autophagy in human alveolar macrophages. BMC Pulm Med. 2014-09-25 [PMID: 25253572] (WB, EM, Human)	WB, EM	Human
Pacheco FJ, Almaguel FG, Evans W et al. Docosahexanoic acid antagonizes TNF-alpha-induced necroptosis by attenuating oxidative stress, ceramide production, lysosomal dysfunction, and autophagic features. Inflamm Res 2014-10-01 [PMID: 25095742] (WB)	WB
Frendo-Cumbo S Identification of New IRS1 Interactors in the Regulation of Insulin Signalling and Cell Proliferation Thesis 2021-01-01 (WB)	WB
Vodicka P, Lim J, Williams DT et al. Assessment of Chloroquine Treatment for Modulating Autophagy Flux in Brain of WT and HD Mice. J Huntingtons Dis 2014-07-02 [PMID: 25062859] (WB, Mouse) Details: LC3B antibody used for WB in lysates of brain and muscle tissues of WT and HD (Q175/Q175) mice that received or not the intraperitoneal injections of chloroquine.	WB	Mouse
Haimovici Aladin, Brigger Daniel, Torbett Bruce E et al. Induction of the autophagy-associated gene MAP1S via PU.1 supports APL differentiation. Leuk Res. 2014-07-01 [PMID: 25043887] (Human)		Human
Li Y, Chen C, Yao F et al. AMPK inhibits cardiac hypertrophy by promoting autophagy via mTORC1. Arch. Biochem. Biophys. 2014-07-04 [PMID: 25009141] (WB, Rat, Mouse) Details: LC3B antibody used for WB on hearts of male C57BL/6J mice subjected or not (sham) to cardiac hypertrophy induced by pressure overload performed by descending aortic banding/AB (Fig. 1A). Antibody also used for WB on sham or AB groups treated or not with AMPK activator AICAR or metformin. LC3B WB also performed on cultured Rat's cardiomyocytes transfected with Ad-CA-AMPK or Ad-GFP - treated or not with phenylephrine/PE and/or Rapamycin (Fig. 4A, 4C; Fig. 6C).	WB	Rat, Mouse
Brigger D, Proikas-Cezanne T, Tschan MP. WIPI-dependent autophagy during neutrophil differentiation of NB4 acute promyelocytic leukemia cells. Cell Death Dis 2014-07-04 [PMID: 24991767] (ICC/IF, WB, Human) Details: LC3B antibody used for WB for measuring autophagic flux in SHC002 and shWIPI-1 or shWIPI-2 expressing NB4 cells (human acute promyelocytic leukemic/APL cell lines NB4) upon 1 uM ATRA treatment at day 4 in the presence or absence of bafilomycin A1 (Figure 4a). Antibody also used for ICC-IF application.	ICC/IF, WB	Human
Zhou Y,Sun K,Ma Y et al. Autophagy inhibits chemotherapy-induced apoptosis through downregulating Bad and Bim in hepatocellular carcinoma cells Sci Rep. 2014-06-20 [PMID: 24947039] (WB, Human) Details: LC3B antibody used for WB in human hepatocellular carcinoma cells/HCC cell line SMMC-7721 and HepG2 (transiently transfected with GFP-LC3 plasmids) cultured under low glucose and hypoxia (LH) conditions in the presence or absence of CQ or 3-MA for 8 h (Figure 1C).	WB	Human
Sheng R, Zhang TT, Felice VD et al. Preconditioning stimuli induce autophagy via sphingosine kinase 2 in mouse cortical neurons. J. Biol. Chem. 2014-06-13 [PMID: 24928515] (ICC/IF, IHC-FrFl, Mouse) Details: Used for ICC-IF on murine cortical neurons and IHC-FrFl on mouse brain free floating sections. ICC-IF - Neurons grown on coverglasses fixed for 15 min with 4% PFA and permeablized with PBS/0.1% Triton X-100 for 30 min, blocked with 2% BSA for 1 h at RT, incubated with LC3 (1:800; Novus; NB600-1384) or SPK2 (1:500) at 4°C for 24 h followed by Cy3-conjugated anti-rabbit IgG for 2 h (FIGURE 2A). IHC-FrFl - 24h past isoflurane, C57 mice perfused with PBS/4% PFA-PBS, brains postfixed in 4% PFA/ON, 40 micron-thick coronal sections cut and blocked in 5% normal goat serum, 1% BSA, 0.2% Triton X-100, 0.03% H2O2 in PBS/1 h RT, incubated with 1:800 dilution of LC3-antibody for 48 h at 4C followed by biotinylated anti-rabbit secondary antibody/2 h RT and ABC -DAB detection (FIGURE 6C).	ICC/IF, IHC-FrFl	Mouse
Yang Annan, Rajeshkumar N V, Wang Xiaoxu et al. Autophagy is critical for pancreatic tumor growth and progression in tumors with p53 alterations. Cancer Discov. 2014-05-29 [PMID: 24875860]
Karsli-Uzunbas G, Guo JY, Price SM et al. Autophagy is Required for Glucose Homeostasis and Lung Tumor Maintenance. Cancer Discov. 2014-05-29 [PMID: 24875857] (WB, Mouse)	WB	Mouse
Stein LR, Imai SI. Specific ablation of Nampt in adult neural stem cells recapitulates their functional defects during aging. EMBO J. 2014-05-08 [PMID: 24811750] (WB, Mouse)	WB	Mouse
Stein LR, Wozniak DF, Dearborn JT et al. Expression of nampt in hippocampal and cortical excitatory neurons is critical for cognitive function. J. Neurosci. 2014-04-18 [PMID: 24760840] (WB, Mouse)	WB	Mouse
Pang Y, Si M, Sun B et al. DHA2, a synthesized derivative of bisbibenzyl, exerts antitumor activity against ovarian cancer through inhibition of XIAP and Akt/mTOR pathway. Food Chem. Toxicol. 2014-04-23 [PMID: 24751974] (ICC/IF, WB, Human)	ICC/IF, WB	Human
van der Welle REN, Jobling R, Burns C, Sanza P VPS41 recessive mutation causes ataxia and dystonia with retinal dystrophy and mental retardation by inhibiting HOPS function and mTORC1 signaling bioRxiv (WB, Human)	WB	Human
Meunier E, Dick MS, Dreier RF et al. Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases. Nature. 2014-04-16 [PMID: 24739961] (ICC/IF, Mouse)	ICC/IF	Mouse
Akbari M, Keijzers G, Maynard S et al. Overexpression of DNA ligase III in mitochondria protects cells against oxidative stress and improves mitochondrial DNA base excision repair. DNA Repair (Amst). 2014-02-27 [PMID: 24674627]
Stellrecht CM, Vangapandu HV, Le XF et al. ATP directed agent, 8-chloro-adenosine, induces AMP activated protein kinase activity, leading to autophagic cell death in breast cancer cells. J Hematol Oncol 2014-03-21 [PMID: 24628795] (WB, Human)	WB	Human
Ohshima J, Lee Y et al. Role of mouse and human autophagy proteins in IFN-gamma-induced cell-autonomous responses against Toxoplasma gondii. J Immunol 2014-01-04 [PMID: 24563254] (WB, Mouse)	WB	Mouse
Cebotaru V, Cebotaru L, Kim H et al. Polycystin-1 negatively regulates polycystin-2 expression via the aggresome/autophagosome pathway. J. Biol. Chem. 2014-01-24 [PMID: 24459142] (WB, Canine)	WB	Canine
Takasaka N, Araya J, Hara H et al. Autophagy Induction by SIRT6 through Attenuation of Insulin-like Growth Factor Signaling Is Involved in the Regulation of Human Bronchial Epithelial Cell Senescence. J Immunol 2013-12-23 [PMID: 24367027] (WB, Human)	WB	Human
Lai AY, Lan CP, Hasan S et al. scyllo-Inositol promotes robust mutant Huntingtin protein degradation. J Biol Chem 2013-12-18 [PMID: 24352657] (WB, Rat)	WB	Rat
Huang YL, Chang CL, Tang CH et al. Extrinsic sphingosine 1-phosphate activates S1P5 and induces autophagy through generating endoplasmic reticulum stress in human prostate cancer PC-3 cells. Cell Signal 2013-12-11 [PMID: 24333325] (WB, Human)	WB	Human
Han J, Jung S, Jang J et al. OCIAD2 activates gamma-secretase to enhance amyloid beta production by interacting with nicastrin. Cell Mol Life Sci. 2013-11-24 [PMID: 24270855] (WB, Human)	WB	Human
Karuppan MKM, Ojha CR, Rodriguez M, Lapierre J Zika virus infection during pregnancy and induced brain pathology in beclin1-deficient mouse model bioRxiv 2019-11-15 (WB, Mouse)	WB	Mouse
Chua JPC. Characterizing molecular modifiers of pathogenesis in spinobulbar muscular atrophy. Thesis. 2015-01-01 (WB, Rat)	WB	Rat
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Chua JP, Reddy SL, Merry DE et al. Transcriptional activation of TFEB/ZKSCAN3 target genes underlies enhanced autophagy in spinobulbar muscular atrophy. Hum Mol Genet. 2013-10-31 [PMID: 24150846] (WB, Mouse)	WB	Mouse
Schulze RJ, Weller SG, Schroeder B et al. Lipid droplet breakdown requires Dynamin 2 for vesiculation of autolysosomal tubules in hepatocytes. J Cell Biol. 2013-10-28 [PMID: 24145164]
Chang Megan A, Morgado Micaela, Warren Curtis R et al. p62/SQSTM1 is required for cell survival of apoptosis-resistant bone metastatic prostate cancer cell lines. Prostate. 2014-02-01 [PMID: 24122957] (WB, ICC/IF, Human)	WB, ICC/IF	Human
Dai Y, Zheng K, Clark J et al. Rapamycin drives selection against a pathogenic heteroplasmic mitochondrial DNA mutation. Hum Mol Genet. 2013-10-06 [PMID: 24101601] (ICC/IF, Human)	ICC/IF	Human
Karanasios E, Ktistakis NT. Studying Autophagy: List of Useful Antibodies Produced via a Community Effort. Autophagy at the Cell, Tissue and Organismal Level. 2016-04-24
Armstrong A, Mattsson N, Appelqvist H et al. Lysosomal Network Proteins as Potential Novel CSF Biomarkers for Alzheimer's Disease. Neuromolecular Med. 2013-10-08 [PMID: 24101586] (WB, Human)	WB	Human
Behrens C, Binotti B, Schmidt C et al. Crystal Structure of the Human Short Coiled Coil Protein and Insights into SCOC-FEZ1 Complex Formation. PLoS One. 2013-10-01 [PMID: 24098481] (ICC/IF, WB, Human)	ICC/IF, WB	Human
Gorbea C, Rechsteiner M, Vallejo JG et al. Depletion of the 26S Proteasome Adaptor Ecm29 Increases Toll-Like Receptor 3 Signaling. Sci Signal. 2013-10-01 [PMID: 24084648]
Hung HH, Huang WP, Pan CY. Dopamine- and zinc-induced autophagosome formation facilitates PC12 cell survival. Cell Biol Toxicol. 2013-09-28 [PMID: 24077806] (WB, Rat)	WB	Rat
Zhirnov OP, Klenk HD. Influenza A virus proteins NS1 and HA along with M2 are involved in stimulation of autophagy in infected cells. J Virol. 2013-09-11 [PMID: 24027311] (WB, Primate, Canine, Human)	WB	Primate, Canine, Human
Capurro M, Prashar A, Gao X, Jones N Survival of intracellular pathogens in response to mTORC1- or TRPML1-TFEB-induced xenophagy Autophagy Reports 2023-12-31 (WB)	WB
Hamalainen RH, Manninen T, Koivumaki H et al. Tissue- and cell-type-specific manifestations of heteroplasmic mtDNA 3243A>G mutation in human induced pluripotent stem cell-derived disease model. Proc Natl Acad Sci U S A. 2013-09-17 [PMID: 24003133] (ICC/IF, Human)	ICC/IF	Human
Murray LS, Lu Y, Taggart A et al. Chemical chaperone treatment reduces intracellular accumulation of mutant collagen IV and ameliorates the cellular phenotype of a COL4A2 mutation that causes haemorrhagic stroke. Hum. Mol. Genet. 2014-01-15 [PMID: 24001601] (WB, Human) Details: Primary dermal fibroblasts, Fig 5A, B. ATF6 (1/2000 Imgenex).	WB	Human
Magnaghi P, D'Alessio R, Valsasina B et al. Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death. Nat Chem Biol 2013-07-28 [PMID: 23892893] (WB, Human)	WB	Human
Liu YQ, Ji Y, Li XZ et al. Retigeric acid B-induced mitophagy by oxidative stress attenuates cell death against prostate cancer cells in vitro. Acta Pharmacol Sin 2013-07-29 [PMID: 23892275]
Brigger D, Torbett BE, Chen J et al. Inhibition of GATE-16 attenuates ATRA-induced neutrophil differentiation of APL cells and interferes with autophagosome formation. Biochem Biophys Res Commun 2013-07-24 [PMID: 23891751] (WB, Human)	WB	Human
Guo JY, Karsli-Uzunbas G, Mathew R et al. Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis. Genes Dev 2013-07-01 [PMID: 23824538] (WB, Mouse)	WB	Mouse
Xingyong C, Xicui S, Huanxing S et al. Upregulation of myeloid cell leukemia-1 potentially modulates beclin-1-dependent autophagy in ischemic stroke in rats. BMC Neurosci 2013-05-20 [PMID: 23688351] (IHC-Fr, WB, ICC/IF, Rat)	IHC-Fr, WB, ICC/IF	Rat
Schutz I. Uptake and intracellular delivery of nanoparticles into mammalian cells. Thesis 2016-07-01 (WB, ICC/IF, IF/IHC)	WB, ICC/IF, IF/IHC
Greer AH, Yong T, Fennell K et al. Knockdown of core binding factorbeta alters sphingolipid metabolism. J Cell Physiol 2013-06-29 [PMID: 23813439] (WB, Human)	WB	Human
Ciccia F, Accardo-Palumbo A, Rizzo A et al. Evidence that autophagy, but not the unfolded protein response, regulates the expression of IL-23 in the gut of patients with ankylosing spondylitis and subclinical gut inflammation. Ann Rheum Dis 2013-06-05 [PMID: 23740229]
Clancey LF, Beirl AJ, Linbo TH, Cooper CD. Maintenance of Melanophore Morphology and Survival Is Cathepsin and vps11 Dependent in Zebrafish. PLoS One 2013-05-27 [PMID: 23724125] (WB, Zebrafish)	WB	Zebrafish
Baranski Madrigal Z. Osteosarcoma: searching for new treatment options. Thesis 2016-05-26
Kenzelmann Broz D, Spano Mello S, Bieging KT et al. Global genomic profiling reveals an extensive p53-regulated autophagy program contributing to key p53 responses. Genes Dev 2013-05-01 [PMID: 23651856] (WB, Mouse)	WB	Mouse
Doi H, Adachi H, Katsuno Met al. p62/SQSTM1 Differentially Removes the Toxic Mutant Androgen Receptor via Autophagy and Inclusion Formation in a Spinal and Bulbar Muscular Atrophy Mouse Model. J Neurosci 2013-05-01 [PMID: 23637164] (WB, Rat)	WB	Rat
Roy C, Gagne V, Fernandes MJ, Marceau Fet al. High affinity capture and concentration of quinacrine in polymorphonuclear neutrophils via vacuolar ATPase-mediated ion trapping: Comparison with other peripheral blood leukocytes and implications for the distribution of cationic drugs. Toxicol Appl Pharmacol 2013-04-17 [PMID: 23603060] (WB, Human)	WB	Human
Moriya S, Che XF, Komatsu S et al. Macrolide antibiotics block autophagy flux and sensitize to bortezomib via endoplasmic reticulum stress-mediated CHOP induction in myeloma cells. Int J Oncol 2013-05-01 [PMID: 23546223] (WB, Human)	WB	Human
Lupfer C, Thomas PG, AnPK et al. Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection Nat Immunol 2013-03-24 [PMID: 23525089] (ICC/IF, WB, Mouse)	ICC/IF, WB	Mouse
Wengrod J, Martin L, Wang D et al. The inhibition of nonsense mediated RNA decay activates autophagy Mol Cell Biol 2013-03-18 [PMID: 23508110] (WB, Human)	WB	Human
Selvakumaran M, Amaravadi RK, Vasilevskaya IA, O'Dwyer PJ. Autophagy inhibition sensitizes colon cancer cells to antiangiogenic and cytotoxic therapy. Clin Cancer Res 2013-06-01 [PMID: 23461901] (WB, Human)	WB	Human
Guo L, Stripay JL, Zhang X et al. CaMKIalpha Regulates AMP Kinase-Dependent, TORC-1-Independent Autophagy during Lipopolysaccharide-Induced Acute Lung Neutrophilic Inflammation. J Immunol 2013-04-01 [PMID: 23447692] (IF/IHC, WB, ICC/IF, Mouse)	IF/IHC, WB, ICC/IF	Mouse
Raina K, Agarwal C, Wadhwa R et al. Energy deprivation by silibinin in colorectal cancer cells: a double-edged sword targeting both apoptotic and autophagic machineries. Autophagy 2013-05-01 [PMID: 23445752]
Pallet N, Sirois I, Bell Cet al. A comprehensive characterization of membrane vesicles released by autophagic human endothelial cells. Proteomics 2013-02-22 [PMID: 23436686] (FLOW, Human)	FLOW	Human
Verhaar R, Drukarch B, Bol JG et al. Tissue transglutaminase cross-links beclin 1 and regulates autophagy in MPP+-treated human SH-SY5Y cells. Neurochem Int 2013-02-01 [PMID: 23380076] (WB, Human)	WB	Human
Humbert M, Medova M, Aebersold DM et al. Protective autophagy is involved in resistance towards MET inhibitors in human gastric adenocarcinoma cells Biochem Biophys Res Commun 2013-01-09 [PMID: 23313490] (WB, Human)	WB	Human
Efeyan A, Zoncu R, Chang S et al. Regulation of mTORC1 by the Rag GTPases is necessary for neonatal autophagy and survival Nature 2012-12-23 [PMID: 23263183] (WB, Mouse)	WB	Mouse
Martinet W, Schrijvers DM, Timmermans JP et al. Immunohistochemical analysis of macroautophagy: Recommendations and limitations. Autophagy 2012-12-14 [PMID: 23242143]
Monastyrska I, Ulasli M, Rottier PJ et al. An autophagy-independent role for LC3 in equine arteritis virus replication. Autophagy 2012-11-26 [PMID: 23182945]
Bess AS, Ryde IT, Hinton DE, Meyer JN. UVC-Induced Mitochondrial Degradation via Autophagy Correlates with mtDNA Damage Removal in Primary Human Fibroblasts J Biochem Mol Toxicol 2012-11-06 [PMID: 23132756] (WB, Human)	WB	Human
Gwak HS, Kim TH, Jo GH et al. Silencing of MicroRNA-21 Confers Radio-Sensitivity through Inhibition of the PI3K/AKT Pathway and Enhancing Autophagy in Malignant Glioma Cell Lines PLoS One 2012-01-01 [PMID: 23077620] (WB, Human)	WB	Human
Liao CC, Ho MY, Liang SM, Liang CM. Recombinant protein rVP1 upregulates BECN1-independent autophagy, MAPK1/3 phosphorylation and MMP9 activity via WIPI1/WIPI2 to promote macrophage migration. Autophagy. 2013-01-01 [PMID: 23051912]
Tomoda T, Sumitomo A, Hirota-Tsuyada Y et al. BDNF controls neuropsychiatric manifestation via autophagic regulation of p62 and GABAA receptor trafficking bioRxiv 2018-05-30 (WB, Mouse)	WB	Mouse
Zhang F, Li Y, Tang Z et al. Proliferative and Survival Effects of PUMA Promote Angiogenesis Cell Rep 2012-10-31 [PMID: 23122957] (WB, ICC/IF, Mouse)	WB, ICC/IF	Mouse
Ott CJ, Kopp N, Bird L et al. BET bromodomain inhibition targets both c-Myc and IL7R in high-risk acute lymphoblastic leukemia Blood 2012-10-04 [PMID: 22904298]
Elrick MJ, Yu T, Chung C, Lieberman AP. Impaired proteolysis underlies autophagic dysfunction in Niemann-Pick type C disease Hum Mol Genet 2012-08-23 [PMID: 22872701] (ICC/IF, IF/IHC, Mouse)	ICC/IF, IF/IHC	Mouse
Bray K, Mathew R, Lau A et al. Autophagy Suppresses RIP Kinase-Dependent Necrosis Enabling Survival to mTOR Inhibition plos One 2012-01-01 [PMID: 22848625] (ICC/IF, WB, Human)	ICC/IF, WB	Human
Gal J, Bang Y, Choi HJ. SIRT2 interferes with autophagy-mediated degradation of protein aggregates in neuronal cells under proteasome inhibition Neurochem Int 2012-07-20 [PMID: 22819792] (WB, Human)	WB	Human
Lai AY, McLaurin J. Inhibition of amyloid-beta peptide aggregation rescues the autophagic deficits in the TgCRND8 mouse model of Alzheimer disease Biochim Biophys Acta 2012-07-16 [PMID: 22800931] (WB, Mouse)	WB	Mouse
Wang C, Mendonsa GR, Symington JW et al. Atg16L1 deficiency confers protection from uropathogenic Escherichia coli infection in vivo Proc Natl Acad Sci U S A 2012-06-19 [PMID: 22715292] (IF/IHC, ICC/IF, Mouse)	IF/IHC, ICC/IF	Mouse
Sirois I, Groleau J, Pallet N et al. Caspase activation regulates the extracellular export of autophagic vacuoles. Autophagy 2012-06-01 [PMID: 22692030]
Hancock MK, Hermanson SB, Dolman NJ et al. A quantitative TR-FRET plate reader immunoassay for measuring autophagy Autophagy 2012-08-01 [PMID: 22622129]
Jarboe JS, Anderson JC, Duarte CW et al. MARCKS Regulates Growth and Radiation Sensitivity and Is a Novel Prognostic Factor for Glioma Clin Cancer Res 2012-06-01 [PMID: 22619307] (WB, Human)	WB	Human
Agholme L, Hallbeck M, Benedikz E et al. Amyloid-beta secretion, generation, and lysosomal sequestration in response to proteasome inhibition: involvement of autophagy J Alzheimers Dis 2012-01-01 [PMID: 22555375]
Glick D, Zhang W, Beaton M et al. BNip3 Regulates Mitochondrial Function and Lipid Metabolism in the Liver Mol Cell Biol 2012-07-01 [PMID: 22547685] (WB, Mouse)	WB	Mouse
Chang Y, Yan W, He X et al. miR-375 Inhibits Autophagy and Reduces Viability of Hepatocellular Carcinoma Cells Under Hypoxic Conditions. Gastroenterology. 2012-04-12 [PMID: 22504094] (WB, Human)	WB	Human
Scheibye-Knudsen M, Ramamoorthy M, Sykora P, Maynard S, Lin PC, Minor RK, Wilson Iii DM, Cooper M, Spencer R, de Cabo R, Croteau DL, Bohr VA. Cockayne syndrome group B protein prevents the accumulation of damaged mitochondria by promoting mitochondrial autophagy. J Exp Med;209(4):855-69. 2012-04-09 [PMID: 22473955] (WB, Human)	WB	Human
Delk NA, Farach-Carson MC. Interleukin-6: a bone marrow stromal cell paracrine signal that induces neuroendocrine differentiation and modulates autophagy in bone metastatic PCa cells Autophagy 2012-04-01 [PMID: 22441019]
Ordonez MP, Roberts EA, Kidwell CU et al. Disruption and therapeutic rescue of autophagy in a human neuronal model of Niemann Pick type C1. Hum Mol Genet. 2012-04-11 [PMID: 22437840] (WB, Human)	WB	Human
Kawano A, Tsukimoto M, Mori D et al. Regulation of P2X7-dependent inflammatory functions by P2X4 receptor in mouse macrophages Biochem Biophys Res Commun. 2012-03-30 [PMID: 22405772] (WB, Mouse)	WB	Mouse
Dehvari N, Mahmud T, Persson J et al. Amyloid precursor protein accumulates in aggresomes in response to proteasome inhibitor. Neurochem Int 2012-04-01 [PMID: 22366649] Details: Using the Biotin conjugated version of NB600-1384, catalog number NB600-1384B.
Congdon EE, Wu JW, Myeku N et al. Methylthioninium chloride (methylene blue) induces autophagy and attenuates tauopathy in vitro and in vivo Autophagy 2012-04-01 [PMID: 22361619]
Ma X, Jin M, Cai Y et al. Mitochondrial electron transport chain complex III is required for antimycin A to inhibit autophagy. Chem Biol 2011-11-23 [PMID: 22118681]
Zheng L, Terman A, Hallbeck M et al. Macroautophagy-generated increase of lysosomal amyloid b-protein mediates oxidant-induced apoptosis of cultured neuroblastoma cells. Autophagy 2011-01-01 [PMID: 22108004] Details: Using the Biotin conjugated version of NB600-1384, catalog number NB600-1384B.
AnPK, Tait SW, Lamkanfi M et al. TLR2 and RIP2 pathways mediate autophagy of Listeria monocytogenes via ERK activation. J Biol Chem. 2011-10-27 [PMID: 22033934]
Yu Z, Wang AM, Adachi H et al. Macroautophagy Is Regulated by the UPR-Mediator CHOP and Accentuates the Phenotype of SBMA Mice. PLoS Genet;7(10). 2011-10-01 [PMID: 22022281]
Zois CE, Giatromanolaki A, Sivridis E et al. Autophagic flux in normal mouse tissues: focus on endogenous LC3A processing. Autophagy 2011-11-01 [PMID: 21997374] (WB, Mouse)	WB	Mouse
Morris S, Swanson MS, Lieberman A et al. Autophagy-Mediated Dendritic Cell Activation Is Essential for Innate Cytokine Production and APC Function with Respiratory Syncytial Virus Responses. J Immunol;187(8):3953-61. 2011-10-15 [PMID: 21911604]
Garcia L, Verdejo HE, Kuzmicic J, Zalaquett R, Gonzalez S, Lavandero S, Corbalan R. Impaired cardiac autophagy in patients developing postoperative atrial fibrillation. J Thorac Cardiovasc Surg;143(2):451-9. 2012-02-01 [PMID: 21885071] (WB, EM, Human)	WB, EM	Human
Sobolewska A, Motyl T, Gajewska M. Role and regulation of autophagy in the development of acinar structures formed by bovine BME-UV1 mammary epithelial cells. Eur J Cell Biol. 2011-08-23 [PMID: 21868124] (WB, Bovine)	WB	Bovine
Castino R, Fiorentino I, Cagnin M et al. Chelation of lysosomal iron protects dopaminergic SH-SY5Y neuroblastoma cells from hydrogen peroxide toxicity by precluding autophagy and Akt dephosphorylation. Toxicol Sci. 2011-07-08 [PMID: 21742779]
Desmolaize B, Rose S, Wilhelm C et al. Combinations of macrolide resistance determinants in field isolates of Mannheimia haemolytica and Pasteurella multocida. Antimicrob Agents Chemother 2011-09-01 [PMID: 21709086]
Ling Y-H, Aracil M, Zou Y et al. PM02734 Induces Caspase-Independent Cell Death Associated with Features of Autophagy, Inhibition of the Akt/mTOR Signaling Pathway, and Activation of DAP Kinase. Clin Cancer Res. 2011-06-20 [PMID: 21690574] (WB, IHC-P, Human)	WB, IHC-P	Human
Crisan TO, Plantinga TS, van de Veerdonk FL et al. Inflammasome-Independent Modulation of Cytokine Response by Autophagy in Human Cells. PLoS ONE. 2011-04-07 [PMID: 21490934]
Haspel J, Shaik RS, Ifedigbo E et al. Characterization of macroautophagic flux in vivo using a leupeptin-based assay. Autophagy 2011-06-01 [PMID: 21460622] (WB, Mouse)	WB	Mouse
Yang S, Wang X, Contino G et al. Pancreatic cancers require autophagy for tumor growth. Genes Dev. 2011-03-15 [PMID: 21406549]
Xu P, Das M, Reilly J, Davis RJ. JNK regulates FoxO-dependent autophagy in neurons. Genes Dev;25(4):310-322. 2011-02-15 [PMID: 21325132] (IHC-P, WB, ICC/IF, Mouse)	IHC-P, WB, ICC/IF	Mouse
Kudo LC, Parfenova L, Ren G et al. Puromycin-Sensitive Aminopeptidase (PSA/NPEPPS) Impedes Development of Neuropathology in hPSA/TAUP301L Double Transgenic Mice. Hum Mol Genet. 2011-02-14 [PMID: 21320871]
Appelqvist H, Nilsson C, Garner B et al. Attenuation of the lysosomal death pathway by lysosomal cholesterol accumulation Am J Pathol. 2011-02-01 [PMID: 21281795] (WB)	WB
Lithanatudom P, Wannatung T, Leecharoenkiat A, Svasti S, Fucharoen S, Smith DR. Enhanced activation of autophagy in ?-thalassemia/Hb E erythroblasts during erythropoiesis. Ann Hematol;90(7):747-58. 2011-07-01 [PMID: 21221583] (WB, ICC/IF, Human)	WB, ICC/IF	Human
Thomas KJ, McCoy MK, Blackinton J et al. DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy. Hum Mol Genet;20(1):40-50. 2011-01-01 [PMID: 20940149]
Koesters R, Kaissling B, Lehir M et al. Tubular overexpression of transforming growth factor-beta1 induces autophagy and fibrosis but not mesenchymal transition of renal epithelial cells. Am J Pathol 2010-08-01 [PMID: 20616344] (IHC-P, Mouse)	IHC-P	Mouse
Fukaya T, Takagi H, Sato Y et al. Crucial roles of B7-H1 and B7-DC expressed on mesenteric lymph node dendritic cells in the generation of antigen-specific CD4+Foxp3+ regulatory T cells in the establishment of oral tolerance. Blood 2010-09-30 [PMID: 20574047] (WB, Mouse)	WB	Mouse
Li X, Wang CE, Huang S et al. Inhibiting the ubiquitin-proteasome system leads to preferential accumulation of toxic N-terminal mutant huntingtin fragments. Hum Mol Genet 2010-06-15 [PMID: 20354076] (WB, Mouse, Human)	WB	Mouse, Human
Liu M-T, Kuan Y-H, Wang J et al. 5-HT4 Receptor-Mediated Neuroprotection Neurogenesis in the Enteric Nervous System of Adult Mice. J Neurosci;29(31):9683-9699. 2009-01-01 [PMID: 19657021] (ICC/IF, Mouse)	ICC/IF	Mouse
Yu WH, Dorado B, Figueroa HY et al. Metabolic Activity Determines Efficacy of Macroautophagic Clearance of Pathological Oligomeric {alpha}-Synuclein. Am J Pathol 175(2):736-747. 2009-01-01 [PMID: 19628769] (ICC/IF, WB, Human, Mouse)	ICC/IF, WB	Human, Mouse
Dien Bard J, Gelebart P, Anand M et al. IL-21 contributes to JAK3/STAT3 activation and promotes cell growth in ALK-positive anaplastic large cell lymphoma. Am J Pathol 2009-08-01 [PMID: 19608866] (ICC/IF, Human)	ICC/IF	Human
Wei J, Fujita M, Nakai M et al. Protective role of endogenous gangliosides for lysosomal pathology in a cellular model of synucleinopathies. Am J Pathol 2009-05-01 [PMID: 19349362] (ICC/IF, WB, Human)	ICC/IF, WB	Human
Montie HL, Cho MS, Holder L et al. Cytoplasmic retention of polyglutamine-exped rogen receptor ameliorates disease via autophagy in a mouse model of spinal bulbar muscular atrophy. Hum Mol Genet;18(11):1937-1950. 2009-01-01 [PMID: 19279159] (WB, ICC/IF, Mouse)	WB, ICC/IF	Mouse
Ulasov IV, Sonabend AM, Nandi S et al. Combination of adenoviral virotherapy and temozolomide chemotherapy eradicates malignant glioma through autophagic and apoptotic cell death in vivo. Br J Cancer 2009-04-07 [PMID: 19277041] (FLOW, IHC-P, Human)	FLOW, IHC-P	Human
Jiang H, White EJ, Conrad C et al. Autophagy pathways in glioblastoma. Methods Enzymol 2009-01-01 [PMID: 19216911]
Gao M, Yeh PY, Lu YS et al. OSU-03012, a novel celecoxib derivative, induces reactive oxygen species-related autophagy in hepatocellular carcinoma. Cancer Res;68(22):9348-57. 2008-11-15 [PMID: 19010909] (WB, ICC/IF, Human)	WB, ICC/IF	Human
Tafani M, Schito L, Anwar T et al. Induction of autophagic cell death by a novel molecule is increased by hypoxia. Autophagy;4(4):467-75. 2008-01-01 [PMID: 18927491] (WB, ICC/IF, Human)	WB, ICC/IF	Human
Aoki H, Kondo Y, Aldape K et al. Autophagy. Monitoring autophagy in glioblastoma with antibody against isoform B of human microtubule-associated protein 1 light chain 3. 2008-05-16 [PMID: 18259115] (WB, IHC-P, ICC/IF, IHC-Fr, Human)	WB, IHC-P, ICC/IF, IHC-Fr	Human
Pyo JO, Nah J, Kim HJ et al. Compensatory activation of ERK1/2 in Atg5-deficient mouse embryo fibroblasts suppresses oxidative stress-induced cell death. Autophagy;4(3):315-21. 2008-04-01 [PMID: 18196969]
Show All 397 Publications. Collapse Publications.

Images	Ratings	Applications	Species	Date	Details
	5 reviewed by: Verified Customer	WB	Mouse	04/16/2022	View Summary Application Western Blot Sample Tested CT26 cells Species Mouse Lot NB600-1384
Enlarge	4 reviewed by: Verified Customer	WB	Mouse	07/17/2019	View Summary Application Western Blot Sample Tested Bone Marrrow Derived Macrophages Species Mouse Lot CF-1 Comments Comments Secondary antibody used: Alexa Fluor 488
Enlarge	4 reviewed by: Verified Customer	WB	Human	06/04/2018	View Summary Application Western Blot Sample Tested Hek 293T cell lysate Species Human Lot CC-1
Enlarge	5 reviewed by: Bo Ding	WB	Mouse	02/20/2018	View Summary Application Western Blot Sample Tested 20 ug whole cell lysate Species Mouse Lot CJ-1
Enlarge	4 reviewed by: Verified Customer	WB	Mouse	07/22/2016	View Summary Application Western Blot Sample Tested Whole cell lysate Species Mouse Lot BQ
Enlarge	5 reviewed by: Verified Customer	WB	Mouse	06/28/2016	View Summary Application Western Blot Sample Tested mice primary macrophages Species Mouse Lot BO
Enlarge	5 reviewed by: Verified Customer	Immunocytochemistry-Paraffin	Human	02/04/2015	View Summary Application Immunocytochemistry-Paraffin Species Human
	4 reviewed by: Verified Customer	IF	Mouse	12/23/2014	View Summary Application Immunofluorescence Sample Tested See PMID 23525089 Species Mouse
	5 reviewed by: Verified Customer	IF	Rat	12/23/2014	View Summary Application Immunofluorescence Sample Tested See PMID 23688351 Species Rat
Enlarge	5 reviewed by: Verified Customer	WB	Human	11/25/2014	View Summary Application Western Blot Sample Tested IB3-1 whole cell lysate Species Human Lot trial sample
Enlarge	4 reviewed by: Verified Customer	WB	Mouse	11/23/2014	View Summary Application Western Blot Sample Tested mouse hearts Species Mouse
Enlarge	5 reviewed by: Verified Customer	WB	Rat	11/01/2014	View Summary Application Western Blot Sample Tested Rat brain Species Rat
	4 reviewed by: Verified Customer	WB	Mouse	10/03/2014	View Summary Application Western Blot Sample Tested Whole cell lysate alveolar macrophages Species Mouse
Enlarge	4 reviewed by: Mohammad Abedi	WB	Human	07/10/2014	View Summary Application Western Blot Sample Tested Neuroblastoma whole cell lysate Species Human Lot 1384
Enlarge	4 reviewed by: Bryan Tinsley	WB	Human	06/10/2014	View Summary Application Western Blot Species Human
Enlarge	5 reviewed by: Bryan Tinsley	ICC	Human	06/10/2014	View Summary Application Immunocytochemistry Species Human
	3 reviewed by: Verified Customer	IHC	Human	10/19/2010	View Summary Application Immunohistochemistry Sample Tested Human Esophagus tissue Species Human
	2 reviewed by: Verified Customer	IF	Other	08/28/2009	View Summary Application Immunofluorescence Sample Tested Human Oral Keratinocyte Species Other Lot K
	4 reviewed by: Verified Customer	WB	Mouse	05/26/2009	View Summary Application Western Blot Sample Tested mouse liver tissue, Sample Amount: 100 Species Mouse Lot I1

Array NB600-1384

• LC3B Antibodies
• LC3B Proteins